ORBIMED ADVISORS LLC

New York, NY · CIK 1055951 · 13F filing filed 2026-08-14

SEC-registered investment adviser since 2002 · limited liability company

Assets managed$20.6bn
Staff118 · 86 in investment roles
Main clients (by assets)Private funds 100%
Private funds24 (5 hedge) · $19.0bn gross assets
Form ADV · 2026-08-18SEC adviser record

Legal entityORBIMED ADVISORS LLC (US)

$5.3bn reported value +15.1% vs Q1 2026

121positions

43.0%in top 10

35 new 32 added 26 reduced 22 sold out vs Q1 2026

Options: 6 call positions ($68.5m notional), 2 put positions ($48.8m notional) – listed below, not included above.

This report includes the holdings of 1 other manager that shares the investment decisions:

ORBIMED CAPITAL LLC – reports through this filing

Shares in two reports are counted once in each security's totals.

Holdings, Q2 2026

The small lines show how much was held over the last 4 quarters (adjusted for stock splits).

#	Security	Ticker	Shares	Value	% of portfolio	Change	Shares change
1	EDGEWISE THERAPEUTICS INC COM EWTX	EWTX	15,518,492	$630.5m11.94%	11.94%	Unchanged
2	ENLIVEN THERAPEUTICS INC COM ELVN	ELVN	6,776,632	$343.9m6.51%	6.51%	Reduced -1.2m	-1,182,906 -14.9%
3	ELI LILLY & CO COM LLY	LLY	257,900	$309.3m5.86%	5.86%	Added +21.1k	+21,100 8.9%
4	MBX BIOSCIENCES INC COM MBX	MBX	3,428,736	$189.3m3.58%	3.58%	Reduced -209.2k	-209,151 -5.8%
5	SINOVAC BIOTECH LTD SHS SVA	SVA	2,718,735	$184.5m3.49%	3.49%	Unchanged
6	ASTRAZENECA PLC ORD AZN	AZN	915,700	$171.1m3.24%	3.24%	Added +245.5k	+245,500 36.6%
7	STRUCTURE THERAPEUTICS INC SPONSORED ADS GPCR	GPCR	2,209,400	$118.6m2.25%	2.25%	Added +734.0k	+733,997 49.8%
8	SIONNA THERAPEUTICS INC COM SION	SION	2,555,877	$112.4m2.13%	2.13%	Reduced -974.8k	-974,825 -27.6%
9	CORVUS PHARMACEUTICALS INC COM CRVS	CRVS	7,165,006	$107.0m2.03%	2.03%	Unchanged
10	ARRIVENT BIOPHARMA INC COM AVBP	AVBP	3,027,328	$105.2m1.99%	1.99%	Unchanged
11	GUARDANT HEALTH INC COM GH	GH	583,700	$87.6m1.66%	1.66%	Added +148.5k	+148,500 34.1%
12	ARGENX SE SPONSORED ADR ARGX	ARGX	92,880	$86.2m1.63%	1.63%	Reduced -44.0k	-44,020 -32.1%
13	MERCK & CO INC COM MRK	MRK	663,400	$85.2m1.61%	1.61%	Unchanged
14	UNIQURE NV SHS QURE	QURE	1,807,486	$83.3m1.58%	1.58%	Reduced -328.7k	-328,663 -15.4%
15	PRAXIS PRECISION MEDICINES I COM NEW PRAX	PRAX	230,100	$77.0m1.46%	1.46%	Added +57.6k	+57,600 33.4%
16	EDWARDS LIFESCIENCES CORP COM EW	EW	834,900	$75.5m1.43%	1.43%	Reduced -395.7k	-395,700 -32.2%
17	PRELUDE THERAPEUTICS INC COM PRLD	PRLD	13,724,571	$73.2m1.39%	1.39%	Added +2.8m	+2,815,315 25.8%
18	ABIVAX SA SPONSORED ADS ABVX	ABVX	546,522	$72.8m1.38%	1.38%	Added +80.8k	+80,822 17.4%
19	DYNE THERAPEUTICS INC COM DYN	DYN	3,235,684	$71.9m1.36%	1.36%	Added +317.8k	+317,800 10.9%
20	NATERA INC COM NTRA	NTRA	262,000	$71.1m1.35%	1.35%	Unchanged
21	CG ONCOLOGY INC COM CGON	CGON	972,800	$69.1m1.31%	1.31%	Added +24.5k	+24,533 2.6%
22	UNITEDHEALTH GROUP INC COM UNH	UNH	161,100	$67.0m1.27%	1.27%	New
23	ARS PHARMACEUTICALS INC COM SPRY	SPRY	8,288,510	$66.4m1.26%	1.26%	Unchanged
24	ASCENDIS PHARMA A/S ORD SHS ASND	ASND	244,456	$65.2m1.24%	1.24%	New
25	HUMANA INC COM HUM	HUM	164,100	$65.2m1.23%	1.23%	New
26	COGENT BIOSCIENCES INC COM COGT	COGT	1,681,300	$65.1m1.23%	1.23%	Added +1.4m	+1,359,200 422.0%
27	BOSTON SCIENTIFIC CORP COM BSX	BSX	1,483,200	$63.3m1.20%	1.20%	Reduced -898.9k	-898,900 -37.7%
28	INTUITIVE SURGICAL INC COM NEW ISRG	ISRG	157,900	$62.8m1.19%	1.19%	Reduced -50.8k	-50,800 -24.3%
29	MINERALYS THERAPEUTICS INC COM MLYS	MLYS	2,110,300	$56.9m1.08%	1.08%	Added +57.4k	+57,400 2.8%
30	ODYSSEY THERAPEUTICS INC COMMON STOCK ODTX	ODTX	3,001,198	$56.2m1.06%	1.06%	New
31	XENON PHARMACEUTICALS INC COM XENE	XENE	892,471	$53.9m1.02%	1.02%	Reduced -167.5k	-167,500 -15.8%
32	ARCUTIS BIOTHERAPEUTICS INC COM ARQT	ARQT	2,042,000	$53.5m1.01%	1.01%	New
33	BRISTOL-MYERS SQUIBB CO COM BMY	BMY	925,000	$53.3m1.01%	1.01%	Unchanged
34	Q32 BIO INC COM QTTB	QTTB	4,127,987	$52.6m1.00%	1.00%	Added +1.9m	+1,875,000 83.2%
35	STRYKER CORPORATION COM SYK	SYK	159,100	$50.1m0.95%	0.95%	Reduced -23.4k	-23,400 -12.8%
36	CARIS LIFE SCIENCES INC COM CAI	CAI	2,806,811	$50.0m0.95%	0.95%	Unchanged
37	THERMO FISHER SCIENTIFIC INC COM TMO	TMO	90,700	$45.5m0.86%	0.86%	Added +44.2k	+44,200 95.0%
38	PALVELLA THERAPEUTICS INC NE COM PVLA	PVLA	292,360	$44.7m0.85%	0.85%	Added +157.8k	+157,760 117.2%
39	ELEVANCE HEALTH INC COM ELV	ELV	114,700	$44.4m0.84%	0.84%	Unchanged
40	SHATTUCK LABS INC COM STTK	STTK	6,306,127	$43.8m0.83%	0.83%	Unchanged
41	UPSTREAM BIO INC COM UPB	UPB	5,693,589	$39.4m0.75%	0.75%	Unchanged
42	CRINETICS PHARMACEUTICALS IN COM CRNX	CRNX	999,000	$37.4m0.71%	0.71%	Unchanged
43	RHYTHM PHARMACEUTICALS INC COM RYTM	RYTM	322,900	$35.9m0.68%	0.68%	Added +8.8k	+8,800 2.8%
44	SYNDAX PHARMACEUTICALS INC COM SNDX	SNDX	1,542,000	$33.7m0.64%	0.64%	Added +579.7k	+579,700 60.2%
45	FORTE BIOSCIENCES INC COM NEW FBRX	FBRX	1,577,705	$33.5m0.64%	0.64%	Added +380.8k	+380,750 31.8%
46	COMPASS THERAPEUTICS INC COM CMPX	CMPX	15,219,994	$33.3m0.63%	0.63%	Unchanged
47	NEKTAR THERAPEUTICS COM NEW NKTR	NKTR	465,346	$32.5m0.62%	0.62%	Added +190.3k	+190,346 69.2%
48	KRYSTAL BIOTECH INC COM KRYS	KRYS	83,200	$30.9m0.59%	0.59%	Added +14.1k	+14,100 20.4%
49	N/A 0 0		5,680,186	$30.3m0.57%	0.57%	Reduced -530.7k	-530,713 -8.5%
50	AXSOME THERAPEUTICS INC COM AXSM	AXSM	117,578	$28.8m0.55%	0.55%	Reduced -96.3k	-96,343 -45.0%
51	KINIKSA PHARMACEUTICALS INTL ORD SHS CL A KNSA	KNSA	420,600	$26.9m0.51%	0.51%	Added +240.0k	+240,001 132.9%
52	TREVI THERAPEUTICS INC COM TRVI	TRVI	1,430,293	$26.7m0.51%	0.51%	Reduced -1.0m	-1,024,107 -41.7%
53	DISC MEDICINE INC COM IRON	IRON	357,535	$26.2m0.50%	0.50%	Reduced -710.0k	-710,015 -66.5%
54	WEST PHARMACEUTICAL SVSC INC COM WST	WST	70,600	$25.3m0.48%	0.48%	New
55	RELMADA THERAPEUTICS INC COM RLMD	RLMD	3,631,195	$25.1m0.48%	0.48%	Reduced -1.1m	-1,084,669 -23.0%
56	UROGEN PHARMA LTD COM URGN	URGN	676,187	$24.9m0.47%	0.47%	Reduced -199.3k	-199,300 -22.8%
57	SUTRO BIOPHARMA INC COM SHS STRO	STRO	743,944	$24.7m0.47%	0.47%	Reduced -57.2k	-57,200 -7.1%
58	SAVARA INC COM SVRA	SVRA	3,959,900	$24.4m0.46%	0.46%	Added +3.3m	+3,324,900 523.6%
59	NEUROPACE INC COM NPCE	NPCE	1,505,125	$23.9m0.45%	0.45%	Reduced -591.4k	-591,402 -28.2%
60	AURA BIOSCIENCES INC COM AURA	AURA	3,333,333	$23.7m0.45%	0.45%	New
61	ORIC PHARMACEUTICALS INC COM ORIC	ORIC	2,015,000	$21.8m0.41%	0.41%	Reduced -678.9k	-678,929 -25.2%
62	CYBIN INC COM NEW COM NEW		3,271,400	$21.6m0.41%	0.41%	Reduced -561.4k	-561,443 -14.7%
63	BIOCRYST PHARMACEUTICALS INC COM BCRX	BCRX	1,852,000	$18.5m0.35%	0.35%	Added +426.8k	+426,800 29.9%
64	BIOAGE LABS INC COM BIOA	BIOA	752,153	$18.4m0.35%	0.35%	Added +40.3k	+40,342 5.7%
65	LEXEO THERAPEUTICS INC COM LXEO	LXEO	3,947,850	$18.4m0.35%	0.35%	Added +345.4k	+345,400 9.6%
66	AADI BIOSCIENCE INC COM WHWK	WHWK	3,934,296	$18.0m0.34%	0.34%	Reduced -231.7k	-231,704 -5.6%
67	DEFINIUM THERAPEUTICS INC COM SHS DFTX	DFTX	365,400	$17.2m0.33%	0.33%	Reduced -438.6k	-438,600 -54.5%
68	SPYRE THERAPEUTICS INC COM NEW SYRE	SYRE	186,145	$16.5m0.31%	0.31%	New
69	CORBUS PHARMACEUTICALS HLDGS COM NEW CRBP	CRBP	1,737,287	$16.3m0.31%	0.31%	Unchanged
70	VERA THERAPEUTICS INC CL A VERA	VERA	369,596	$15.9m0.30%	0.30%	Unchanged
71	ALUMIS INC COM ALMS	ALMS	548,163	$15.4m0.29%	0.29%	Unchanged
72	EYEPOINT PHARMACEUTICALS INC COM NEW EYPT	EYPT	1,069,147	$15.3m0.29%	0.29%	Unchanged
73	WATERS CORP COM WAT	WAT	40,300	$15.1m0.29%	0.29%	New
74	MONOPAR THERAPEUTICS INC COM NEW MNPR	MNPR	157,423	$14.6m0.28%	0.28%	New
75	TRAVERE THERAPEUTICS INC COM TVTX	TVTX	253,000	$14.4m0.27%	0.27%	New
76	TAYSHA GENE THERAPIES INC COM SHS TSHA	TSHA	2,000,000	$13.6m0.26%	0.26%	New
77	BIOGEN INC COM BIIB	BIIB	61,600	$13.3m0.25%	0.25%	Unchanged
78	REVOLUTION MEDICINES INC COM RVMD	RVMD	70,500	$13.2m0.25%	0.25%	Added +18.5k	+18,500 35.6%
79	DIANTHUS THERAPEUTICS INC COM DNTH	DNTH	115,000	$11.2m0.21%	0.21%	New
80	SPRUCE BIOSCIENCES INC COM NEW SPRB	SPRB	200,000	$10.8m0.20%	0.20%	New
81	LIFESTANCE HEALTH GROUP INC COM LFST	LFST	947,400	$10.1m0.19%	0.19%	Added +447.4k	+447,400 89.5%
82	ERASCA INC COM ERAS	ERAS	495,900	$9.1m0.17%	0.17%	New
83	PROTARA THERAPEUTICS INC COM STK TARA	TARA	2,220,000	$8.5m0.16%	0.16%	New
84	KEROS THERAPEUTICS INC COM KROS	KROS	759,155	$8.1m0.15%	0.15%	Unchanged
85	JANUX THERAPEUTICS INC COM JANX	JANX	524,700	$8.1m0.15%	0.15%	Reduced -458.9k	-458,900 -46.7%
86	TECTONIC THERAPEUTIC INC COM TECX	TECX	226,600	$7.8m0.15%	0.15%	Unchanged
87	ADICET BIO INC COM NEW ACET	ACET	844,787	$7.3m0.14%	0.14%	Reduced -183.2k	-183,157 -17.8%
88	PHARVARIS N V COM PHVS	PHVS	205,400	$7.1m0.13%	0.13%	Unchanged
89	ALTO NEUROSCIENCE INC COM SHS ANRO	ANRO	257,852	$6.8m0.13%	0.13%	Added +90.4k	+90,352 53.9%
90	ZENTALIS PHARMACEUTICALS INC COM ZNTL	ZNTL	1,390,576	$6.7m0.13%	0.13%	New
91	BRIGHT MINDS BIOSCIENCES INC COM NEW DRUG	DRUG	93,000	$6.5m0.12%	0.12%	Added +53.0k	+53,000 132.5%
92	ALX ONCOLOGY HLDGS INC COM ALXO	ALXO	2,866,256	$5.9m0.11%	0.11%	Unchanged
93	TRAVERE THERAPEUTICS INC NOTE 0.500% 5/1 · principal TVTX 0.5 05.15.32 · principal	TVTX 0.5 05.15.32	5,000,000	$5.9m0.11%	0.11%	New
94	XILIO THERAPEUTICS INC COM XLO	XLO	592,300	$5.7m0.11%	0.11%	New
95	BICARA THERAPEUTICS INC COM BCAX	BCAX	191,100	$5.7m0.11%	0.11%	Reduced -476.2k	-476,200 -71.4%
96	IMAGENEBIO INC COM IMA	IMA	909,269	$5.4m0.10%	0.10%	Added +530.7k	+530,713 140.2%
97	PROTAGONIST THERAPEUTICS INC COM PTGX	PTGX	42,100	$5.2m0.10%	0.10%	Unchanged
98	ALNYLAM PHARMACEUTICALS INC COM ALNY	ALNY	17,000	$5.1m0.10%	0.10%	Reduced -102.0k	-102,000 -85.7%
99	PALISADE BIO INC COM PALI	PALI	2,333,000	$4.9m0.09%	0.09%	Unchanged
100	REVOLUTION MEDICINES INC NOTE 0.500% 5/0 · principal RVMD 0.5 05.01.33 · principal	RVMD 0.5 05.01.33	3,500,000	$4.4m0.08%	0.08%	New

Sold out since Q1 2026

Security	Ticker	Shares held before	Value then
MYRIAD GENETICS INC MYGN	MYGN	125,000,000	$122.9m125.0m shares
PFIZER INC PFE	PFE	1,946,500	$54.7m1.9m shares
DANAHER CORPORATION DHR	DHR	265,800	$50.4m265.8k shares
ASCENDIS PHARMA A/S		181,977	$41.6m182.0k shares
AVITA MEDICAL INC RCEL	RCEL	40,500,000	$40.5m40.5m shares
ESPERION THERAPEUTICS INC NE ESPR	ESPR	10,570,300	$29.0m10.6m shares
BRIGHTSPRING HEALTH SVCS INC BTSG	BTSG	497,800	$21.2m497.8k shares
AMGEN INC AMGN	AMGN	39,900	$14.0m39.9k shares
ALIGNMENT HEALTHCARE INC ALHC	ALHC	791,000	$13.9m791.0k shares
REGENERON PHARMACEUTICALS REGN	REGN	14,700	$11.4m14.7k shares
CARLSMED INC CARL	CARL	1,252,600	$11.3m1.3m shares
GILEAD SCIENCES INC GILD	GILD	59,600	$8.3m59.6k shares
HERON THERAPEUTICS INC HRTX	HRTX	9,816,940	$7.9m9.8m shares
AVALO THERAPEUTICS INC AVTX	AVTX	475,165	$7.1m475.2k shares
COMPASS PATHWAYS PLC CMPS	CMPS	1,150,646	$6.4m1.2m shares
ADC THERAPEUTICS SA ADCT	ADCT	1,318,026	$4.9m1.3m shares
CULLINAN THERAPEUTICS INC CGEM	CGEM	243,006	$3.5m243.0k shares
JADE BIOSCIENCES INC JBIO	JBIO	185,011	$2.6m185.0k shares
C4 THERAPEUTICS INC CCCC	CCCC	856,353	$2.3m856.4k shares
AVITA MEDICAL INC RCEL	RCEL	544,895	$2.0m544.9k shares
KALVISTA PHARMACEUTICALS INC KALV	KALV	94,400	$1.9m94.4k shares
VISTAGEN THERAPEUTICS INC VTGN	VTGN	3,060,000	$1.7m3.1m shares

Options (notional value)

Underlying	Ticker	Type	Shares controlled	Notional	Change
SPDR SER TR XBI · Put	XBI	Put	300,000	$47.5m300.0k shares	New
ABIVAX SA ABVX · Call	ABVX	Call	200,000	$26.7m200.0k shares	New
PROTAGONIST THERAPEUTICS INC PTGX · Call	PTGX	Call	150,000	$18.4m150.0k shares	New
REVOLUTION MEDICINES INC RVMD · Call	RVMD	Call	50,000	$9.4m50.0k shares	New
PALVELLA THERAPEUTICS INC NE PVLA · Call	PVLA	Call	40,000	$6.1m40.0k shares	Reduced
UNITEDHEALTH GROUP INC UNH · Call	UNH	Call	10,000	$4.2m10.0k shares	New
ELEVANCE HEALTH INC ELV · Call	ELV	Call	10,000	$3.9m10.0k shares	New
SELLAS LIFE SCIENCES GROUP I SLS · Put	SLS	Put	92,500	$1.4m92.5k shares	New

Stakes above 5%

Companies where this manager has reported owning more than 5% of a class of shares, on Schedule 13D (may seek influence) or 13G (passive): its latest filing for each, from 19 Dec 2024 on.

Company	Ticker	Stake	Change	Schedule	Last filed
PRELUDE THERAPEUTICS INC PRLD · 13D · filed 2026-04-23	PRLD	16.0%≈ $68.9m		13D	2026-04-23
EDGEWISE THERAPEUTICS INC EWTX · 13D · filed 2025-05-12	EWTX	14.5%≈ $619.7m		13D	2025-05-12
Q32 BIO INC QTTB · 13D · filed 2026-07-20	QTTB	13.9%≈ $52.6m	-3.5 pts	13D	2026-07-20
IKENA ONCOLOGY INC 13D · filed 2026-04-29		13.1%	+6.2 pts	13D	2026-04-29
TRAWS PHARMA INC TRAW · 13D · filed 2026-05-05	TRAW	11.9%≈ $1.6m	-8.0 pts	13D	2026-05-05
CORVUS PHARMACEUTICALS INC CRVS · 13D · filed 2026-01-27	CRVS	10.3%≈ $128.6m	-1.9 pts	13D	2026-01-27
SHATTUCK LABS INC STTK · 13D · filed 2026-06-15	STTK	10.0%≈ $62.6m	no change	13D	2026-06-15
XILIO THERAPEUTICS INC XLO · 13G · filed 2026-05-15	XLO	10.0%	new	13G	2026-05-15
ENLIVEN THERAPEUTICS INC ELVN · 13D · filed 2026-06-24	ELVN	9.5%≈ $343.8m	-1.4 pts	13D	2026-06-24
COMPASS THERAPEUTICS INC CMPX · 13D · filed 2025-08-15	CMPX	8.9%≈ $33.3m	-2.1 pts	13D	2025-08-15
ADICET BIO INC 13D · filed 2026-04-10		8.8%	-0.8 pts	13D	2026-04-10
INSPIREMD INC NSPR · 13G · filed 2026-02-17	NSPR	7.4%≈ $2.2m	+3.3 pts	13G	2026-02-17
AADI BIOSCIENCE INC WHWK · 13G · filed 2026-08-14	WHWK	7.3%≈ $18.0m	-1.6 pts	13G	2026-08-14
SIONNA THERAPEUTICS INC SION · 13D · filed 2026-04-20	SION	6.6%≈ $130.6m	-1.8 pts	13D	2026-04-20
MBX BIOSCIENCES INC MBX · 13D · filed 2026-08-10	MBX	6.4%≈ $169.7m	-1.3 pts	13D	2026-08-10
FORTE BIOSCIENCES INC FBRX · 13G · filed 2026-08-14	FBRX	6.2%≈ $26.9m	+1.9 pts	13G	2026-08-14
CORBUS PHARMACEUTICALS HLDGS CRBP · 13G · filed 2025-02-14	CRBP	5.9%≈ $6.7m		13G	2025-02-14
ARRIVENT BIOPHARMA INC AVBP · 13D · filed 2026-10-08	AVBP	5.8%≈ $99.9m	-1.7 pts	13D	2026-10-08
IMMUNIC INC 13G · filed 2026-08-14		5.3%	new	13G	2026-08-14

Trades reported as a company insider since 1 Apr 2026

Owning 10% or more of a company, or having someone on its board, makes this manager an insider there: it reports its trades in that company's shares on Form 4 within two business days. Open-market and private purchases and sales only.

Date	Company	Ticker	Trade	Shares	Value	Their holding
2026-07-07	SIONNA THERAPEUTICS INC Director · See footnotes	SION	Sold	85,918	$3.9m85.9k shares	-3%
2026-06-30	SIONNA THERAPEUTICS INC Director · See footnotes	SION	Sold	115,844	$5.3m115.8k shares	-4%
2026-06-22	ENLIVEN THERAPEUTICS INC 10% owner · See Footnotes	ELVN	Sold	860,123	$39.0m860.1k shares	-12%
2026-06-15	ENLIVEN THERAPEUTICS INC 10% owner · See Footnotes	ELVN	Sold	281,408	$12.7m281.4k shares	-4%
2026-05-28	Q32 BIO INC Director · See footnotes	QTTB	Bought	1,875,000	$15.0m1.9m shares	new
2026-05-27	SIONNA THERAPEUTICS INC Director · See footnotes	SION	Sold	101	$4.5k101 shares	-<1%
2026-05-11	SIONNA THERAPEUTICS INC Director · See footnotes(	SION	Sold	184,639	$8.5m184.6k shares	-6%
2026-05-08	SIONNA THERAPEUTICS INC Director · See footnotes(	SION	Sold	59,767	$2.7m59.8k shares	-2%
2026-05-07	SIONNA THERAPEUTICS INC Director · See footnotes(	SION	Sold	48,546	$2.2m48.5k shares	-2%
2026-04-21	PRELUDE THERAPEUTICS INC Director · See footnotes	PRLD	Bought	2,815,315	$12.5m2.8m shares	new
2026-04-18	SIONNA THERAPEUTICS INC Director · See footnotes	SION	Sold	2,948	$131.2k2.9k shares	-<1%
2026-04-17	SIONNA THERAPEUTICS INC Director · See footnotes	SION	Sold	52,397	$2.3m52.4k shares	-2%
2026-04-16	SIONNA THERAPEUTICS INC Director · See footnotes	SION	Sold	226,906	$10.3m226.9k shares	-7%
2026-04-16	TRAWS PHARMA INC 10% owner · See Footnote	TRAW	Bought	597,729	$998.2k597.7k shares	+99%
2026-04-15	SIONNA THERAPEUTICS INC Director · See footnotes	SION	Sold	235,863	$10.5m235.9k shares	-7%
2026-04-14	SIONNA THERAPEUTICS INC Director · See footnotes	SION	Sold	47,814	$2.1m47.8k shares	-1%
2026-04-08	ADICET BIO INC 10% owner · See footnotes	ACET	Sold	72,939	$468.1k72.9k shares	-100%
2026-04-07	ADICET BIO INC 10% owner · See footnotes	ACET	Sold	31,719	$206.8k31.7k shares	-49%