ADICET BIO INC ACET
COM NEW · Common Stock · CUSIP 007002207
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBoston, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $8.64. Options: 2 managers hold calls ($92.9k notional), 4 hold puts ($452.7k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q4 2025 | 48 |
| Q1 2026 | 48 |
| Q2 2026 | 56 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2026 | 21 | 20 |
| Q2 2026 | 32 | 15 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $0 | $0 | — |
| Q4 2025 | $14.3k | $3.4k | 0.24 |
| Q1 2026 | $372.5k | $3.4k | 0.01 |
| Q2 2026 | $92.9k | $452.7k | 4.87 |
Biggest buyers
| Schonfeld Strategic Advisors LLC | New | +195.5k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | New | +86.0k |
| MARSHALL WACE, LLP | New | +79.5k |
| REGENERON PHARMACEUTICALS, INC. | New | +60.5k |
| TWO SIGMA INVESTMENTS, LP | Added | +53.7k |
| CITADEL ADVISORS LLC | Added | +50.9k |
| Quadrature Capital Ltd | New | +36.2k |
| Trexquant Investment LP | Added | +34.3k |
| JANE STREET GROUP, LLC | Added | +33.5k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +33.4k |
Biggest sellers
| Woodline Partners LP | Sold out | -313.1k |
| Prosight Management, LP | Sold out | -250.2k |
| RA CAPITAL MANAGEMENT, L.P. | Reduced | -250.0k |
| ORBIMED ADVISORS LLC | Reduced | -183.2k |
| ADAR1 Capital Management, LLC | Sold out | -53.8k |
| BARCLAYS PLC | Sold out | -25.0k |
| UBS Group AG | Reduced | -8.6k |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | -5.5k |
| Rangeley Capital, LLC | Reduced | -5.1k |
| NewEdge Advisors, LLC | Sold out | -3.9k |
Biggest calls
| CITADEL ADVISORS LLC | New | $92.5k10.7k shares |
| SIMPLEX TRADING, LLC | Reduced | $3971.7k shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $197.0k22.8k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $169.3k19.6k shares |
| SIMPLEX TRADING, LLC | Added | $83.8k9.7k shares |
| GROUP ONE TRADING LLC | Added | $2.6k300 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor -2.4 pts · filed 2026-08-14 | 9.9% |
| FRANKLIN TEMPLETON INC 13G · institution +1.2 pts · filed 2026-10-28 | 7.7% |
| Zedek Daniel Clayton 13G · passive investor new · filed 2026-10-23 | 5.4% |
Fell to 5% or below in the last year: Woodline Partners LP (3.3%, 2026-05-15), TANG CAPITAL MANAGEMENT LLC (0.1%, 2026-02-17)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-04-08 | ORBIMED ADVISORS LLC +7 10% owner · See footnotes | Sold | $468.1k72.9k shares |
| 2026-04-07 | ORBIMED ADVISORS LLC +7 10% owner · See footnotes | Sold | $206.8k31.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 0.07% of their portfolio | 932.6k $8.1m | Reduced -250.0k |
| ORBIMED ADVISORS LLC 0.14% of their portfolio | 844.8k $7.3m | Reduced -183.2k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 626.6k $5.4m | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 432.7k $3.7m | Added +50.9k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 343.2k $3.0m | Added +6.7k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio | 274.4k $2.4m | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 265.9k $2.3m | Added +33.4k |
| Stonepine Capital Management, LLC 1.61% of their portfolio | 245.5k $2.1m | Added +23.6k |
| Alyeska Investment Group, L.P. 0.00% of their portfolio | 203.8k $1.8m | Unchanged |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 195.5k $1.7m | New |
| Carlyle Group Inc. 0.02% of their portfolio | 184.3k $1.6m | Unchanged |
| NEXTBio Capital Management LP 0.63% of their portfolio | 157.8k $1.4m | Unchanged |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 124.8k $1.1m | Added +6.7k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 96.8k $836.7k | Added +53.7k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 95.6k $826.7k | Reduced -5.5k |
| DAFNA Capital Management LLC 0.15% of their portfolio | 93.8k $810.5k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 86.0k $742.7k | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 79.5k $686.8k | New |
| Trexquant Investment LP 0.00% of their portfolio | 78.0k $673.9k | Added +34.3k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 70.6k $609.6k | Added +33.5k |
| Burkehill Global Management, LP 0.02% of their portfolio | 62.5k $540.0k | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 62.1k $536.8k | Added +25.5k |
| REGENERON PHARMACEUTICALS, INC. 0.30% of their portfolio | 60.5k $522.8k | New |
| Rangeley Capital, LLC 0.41% of their portfolio | 50.9k $439.7k | Reduced -5.1k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 50.7k $437.8k | Added +336 |
| RBF Capital, LLC 0.01% of their portfolio | 38.6k $333.3k | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 36.2k $313.0k | Unchanged |
| Quadrature Capital Ltd 0.00% of their portfolio | 36.2k $312.7k | New |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 31.6k $273.0k | Added +20.8k |
| UBS Group AG 0.00% of their portfolio | 29.8k $257.6k | Reduced -8.6k |
| Verdad Advisers, LP 0.21% of their portfolio | 25.2k $217.7k | New |
| XTX Topco Ltd 0.00% of their portfolio | 24.3k $209.8k | Added +5.2k |
| JOHNSON & JOHNSON 0.02% of their portfolio | 22.8k $196.8k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 20.6k $178.4k | New |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 18.6k $160.3k | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 18.4k $159.3k | Reduced -764 |
| OCCUDO QUANTITATIVE STRATEGIES LP 0.01% of their portfolio | 16.6k $143.7k | Added +1.5k |
| Squarepoint Ops LLC 0.00% of their portfolio | 15.3k $131.8k | New |
| Vontobel Holding Ltd. 0.00% of their portfolio | 13.8k $119.0k | Reduced -471 |
| AXQ CAPITAL, LP 0.01% of their portfolio | 11.0k $95.0k | New |
| Jump Financial, LLC 0.00% of their portfolio | 10.9k $94.5k | New |
| Arax Advisory Partners 0.00% of their portfolio | 6.0k $51.8k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 5.2k $45.1k | Unchanged |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 4.8k $41.6k | Added +3.4k |
| MORGAN STANLEY 0.00% of their portfolio | 2.3k $19.8k | Reduced -1.2k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 1.7k $15.0k | Added +2 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 277 $2.4k | Reduced -1.1k |
| Avion Wealth 0.00% of their portfolio | 246 $2.0k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 196 $1.7k | Added +188 |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 50 $432 | Unchanged |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 47 $406 | Added +44 |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 24 $207 | Added +5 |
| NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio | 17 $146 | Unchanged |
| FMR LLC 0.00% of their portfolio | 6 $52 | New |
| TD Waterhouse Canada Inc. 0.00% of their portfolio | 3 $26 | New |
| DANSKE BANK A/S 0.00% of their portfolio | 1 $9 | Unchanged |