ALUMIS INC ALMS
COM · Common Stock · CUSIP 022307102
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($329.9k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $28.12. Options: 11 managers hold calls ($27.3m notional), 6 hold puts ($5.2m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q2 2024 | 30 |
| Q3 2024 | 53 |
| Q4 2024 | 65 |
| Q1 2025 | 73 |
| Q2 2025 | 113 |
| Q3 2025 | 130 |
| Q4 2025 | 134 |
| Q1 2026 | 196 |
| Q2 2026 | 198 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 38 | 16 |
| Q4 2024 | 36 | 10 |
| Q1 2025 | 46 | 14 |
| Q2 2025 | 100 | 15 |
| Q3 2025 | 71 | 45 |
| Q4 2025 | 75 | 59 |
| Q1 2026 | 142 | 57 |
| Q2 2026 | 101 | 85 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $154.6k | $10.5m | 67.76 |
| Q4 2025 | $2.0m | $4.0m | 1.97 |
| Q1 2026 | $22.5m | $9.5m | 0.42 |
| Q2 2026 | $27.3m | $5.2m | 0.19 |
Biggest buyers
| FMR LLC | Added | +5.8m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +1.9m |
| NOVO HOLDINGS A/S | New | +1.1m |
| BlackRock, Inc. | Added | +1.0m |
| Woodline Partners LP | New | +486.1k |
| D. E. Shaw & Co., Inc. | Added | +396.1k |
| STATE STREET CORP | Added | +385.5k |
| CITIGROUP INC | Added | +286.5k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +250.1k |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Added | +208.6k |
Biggest sellers
| UBS Group AG | Reduced | -2.1m |
| MARSHALL WACE, LLP | Reduced | -804.7k |
| Weiss Asset Management LP | Reduced | -786.0k |
| Cormorant Asset Management, LP | Reduced | -663.6k |
| Yu Fan | Reduced | -524.2k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | Reduced | -428.2k |
| Deep Track Capital, LP | Reduced | -424.0k |
| PRUDENTIAL FINANCIAL INC | Reduced | -376.1k |
| MPM BIOIMPACT LLC | Reduced | -367.5k |
| Point72 Asset Management, L.P. | Sold out | -363.0k |
Biggest calls
| Ikarian Capital, LLC | Added | $10.0m356.3k shares |
| DIADEMA PARTNERS LP | Added | $5.6m200.0k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | $2.9m104.6k shares |
| Caption Management, LLC | Unchanged | $2.8m100.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.5m88.5k shares |
| CITADEL ADVISORS LLC | Reduced | $1.6m56.2k shares |
| JANE STREET GROUP, LLC | Reduced | $681.0k24.2k shares |
| Persistent Asset Partners Ltd | Added | $443.7k508 shares |
| Point72 Asset Management, L.P. | Added | $343.3k12.2k shares |
| SIMPLEX TRADING, LLC | Reduced | $202.6k7.2k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.0m72.5k shares |
| CITADEL ADVISORS LLC | Reduced | $1.2m43.5k shares |
| JANE STREET GROUP, LLC | Added | $1.1m40.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $377.1k13.4k shares |
| Point72 Asset Management, L.P. | Added | $343.3k12.2k shares |
| GROUP ONE TRADING LLC | Reduced | $118.2k4.2k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Foresite Capital Fund VI LP
13D · may seek influence
-1.4 pts · filed 2026-04-03
Stated purposeThe Reporting Persons hold their securities of the Issuer for investment purposes. Depending on the factors discussed herein, the Reporting Persons may, from time to time, acquire additional shares of Common Stock and/or retain and/or sell all or a portion of the Common Stock held by the Reporting Persons in the open market or in privately negotiated transactions, and/or may distribute the Common Stock held by the Reporting Persons to their respective members or limited partners. Any actions the Reporting Persons might undertake will be dependent upon the Reporting Persons' review of numerous factors, including, among other things, the price levels of the Common Stock; general market and economic conditions; ongoing evaluation of the Issuer's business, financial condition, operations and p… Full filing |
12.7% |
| AyurMaya Capital Management Company, LP 13D · may seek influence -3.5 pts · filed 2026-07-02 | 12.3% |
| Deep Track Capital, LP 13G · passive investor new · filed 2026-04-07 | 6.0% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-27 | 5.7% |
| FMR LLC 13G · institution new · filed 2026-08-06 | 5.5% |
| Samsara BioCapital, L.P. 13D · may seek influence +0.1 pts · filed 2026-01-13 | 5.4% |
Fell to 5% or below in the last year: venBio Global Strategic Fund IV, L.P. (4.8%, 2025-11-17)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 4 | $1.9m | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 2 | $12.7m | 0 | — | — |
| Q1 2026 | 2 | $17.0m | 0 | — | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 1 | $10.7m | 7 | $1.5m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-08 | AKKARAJU SRINIVAS Director · By Samsara BioCapital, L.P. | Bought | $2.9m273.3k shares |
| 2026-09-08 | AKKARAJU SRINIVAS Director · By Samsara Opportunity Fund, L.P. | Bought | $2.9m273.3k shares |
| 2026-09-08 | AKKARAJU SRINIVAS Director · By Samsara BioCapital, L.P. | Sold | $507.1k48.1k shares |
| 2026-09-08 | AKKARAJU SRINIVAS Director · By Samsara Opportunity Fund, L.P. | Sold | $507.1k48.1k shares |
| 2026-09-04 | AKKARAJU SRINIVAS Director · By Samsara BioCapital, L.P. | Bought | $2.5m220.1k shares |
| 2026-09-04 | AKKARAJU SRINIVAS Director · By Samsara Opportunity Fund, L.P. | Bought | $2.5m220.1k shares |
| 2026-08-03 | Schroer John R. Chief Financial Officer | Sold | $86.5k3.3k shares |
| 2026-08-03 | Hardiman Roy C. Chief Business & Strategy Ofcr | Sold | $71.0k2.7k shares |
| 2026-08-03 | Goldstein David M Chief Scientific Officer | Sold | $68.5k2.6k shares |
| 2026-08-03 | Bradley Mark Christopher Chief Development Officer | Sold | $67.8k2.6k shares |
| 2026-08-03 | Drappa Jorn Chief Medical Officer | Sold | $64.5k2.4k shares |
| 2026-08-03 | Pangali Sanam Chief Legal Officer | Sold | $36.0k1.4k shares |
| 2026-07-06 | Pangali Sanam Chief Legal Officer | Sold | $140.0k5.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| AyurMaya Capital Management Company, LP 100.00% of their portfolio | 15.1m $426.0m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 8.2m $231.3m | Added +1.0m |
| FMR LLC 0.01% of their portfolio | 6.8m $190.5m | Added +5.8m |
| Deep Track Capital, LP 2.63% of their portfolio | 6.3m $178.6m | Reduced -424.0k |
| SAMSARA BIOCAPITAL, LLC 14.67% of their portfolio | 6.3m $178.6m | Unchanged |
| Foresite Capital Management V, LLC 45.81% of their portfolio | 5.9m $165.9m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 5.2m $146.3m | Added +1.9m |
| venBio Partners LLC 24.53% of their portfolio | 4.5m $127.4m | Unchanged |
| Foresite Capital Management VI LLC 18.60% of their portfolio | 4.2m $119.5m | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 4.2m $118.6m | Added +183.4k |
| Nextech Invest Ltd. 4.73% of their portfolio | 3.5m $99.6m | Unchanged |
| Cormorant Asset Management, LP 4.74% of their portfolio | 3.3m $92.5m | Reduced -663.6k |
| Saturn V Capital Management LP 11.76% of their portfolio | 2.9m $82.0m | Reduced -286.6k |
| Octagon Capital Advisors LP 7.31% of their portfolio | 2.8m $79.7m | Unchanged |
| Jupiter Topco LLC 0.03% of their portfolio | 2.4m $66.2m | First filing |
| STATE STREET CORP 0.00% of their portfolio | 2.2m $61.5m | Added +385.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.2m $61.0m | Added +250.1k |
| MPM BIOIMPACT LLC 3.46% of their portfolio | 2.0m $56.8m | Reduced -367.5k |
| BAKER BROS. ADVISORS LP 0.28% of their portfolio | 2.0m $56.6m | Unchanged |
| SR One Capital Management, LP 5.31% of their portfolio | 2.0m $55.2m | Unchanged |
| Invesco Ltd. 0.00% of their portfolio | 1.2m $33.0m | Reduced -338.0k |
| NOVO HOLDINGS A/S 1.80% of their portfolio | 1.1m $31.0m | New |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 1.1m $30.1m | Added +10.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 969.6k $26.4m | Added +108.0k |
| D. E. Shaw & Co., Inc. 0.02% of their portfolio | 968.2k $27.2m | Added +396.1k |
| UBS Group AG 0.00% of their portfolio | 951.8k $26.8m | Reduced -2.1m |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 921.2k $25.9m | Added +208.6k |
| Ikarian Capital, LLC 4.01% of their portfolio | 870.5k $24.5m | Reduced -343.0k |
| GREAT POINT PARTNERS LLC 5.68% of their portfolio | 856.1k $24.1m | Unchanged |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 831.9k $23.4m | Added +113.9k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 723.8k $20.4m | Added +160.3k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 700.1k $19.7m | Added +64.7k |
| Integral Health Asset Management, LLC 0.81% of their portfolio | 700.0k $19.7m | Reduced -100.0k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 660.1k $18.6m | Added +53.9k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 612.0k $17.2m | Added +84.7k |
| Opaleye Management Inc. 1.40% of their portfolio | 550.0k $15.5m | Unchanged |
| ORBIMED ADVISORS LLC 0.29% of their portfolio | 548.2k $15.4m | Unchanged |
| ROYCE & ASSOCIATES LP 0.12% of their portfolio | 525.3k $14.8m | Added +48.9k |
| Woodline Partners LP 0.04% of their portfolio | 486.1k $13.7m | New |
| Spruce Street Capital LP 2.17% of their portfolio | 392.6k $11.0m | Unchanged |
| Trium Capital LLP 6.92% of their portfolio | 390.3k $11.0m | Added +198.9k |
| CITIGROUP INC 0.01% of their portfolio | 385.4k $10.8m | Added +286.5k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 376.1k $10.6m | Reduced -282.0k |
| MARSHALL WACE, LLP 0.01% of their portfolio | 368.0k $10.4m | Reduced -804.7k |
| MORGAN STANLEY 0.00% of their portfolio | 321.2k $9.0m | Added +96.1k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.04% of their portfolio | 320.9k $9.0m | Reduced -428.2k |
| Weiss Asset Management LP 0.10% of their portfolio | 311.4k $8.8m | Reduced -786.0k |
| Artia Global Partners LP 1.49% of their portfolio | 278.5k $7.8m | Reduced -46.5k |
| BARCLAYS PLC 0.00% of their portfolio | 273.7k $7.7m | Added +51.1k |
| Yu Fan 6.59% of their portfolio | 252.7k $7.1m | Reduced -524.2k |
| Nuveen, LLC 0.00% of their portfolio | 243.9k $6.9m | Reduced -75.3k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.13% of their portfolio | 242.5k $6.8m | Reduced -103.6k |
| Omega Fund Management, LLC 3.66% of their portfolio | 241.3k $6.8m | Unchanged |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 236.8k $6.4m | Added +99.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 226.6k $6.4m | Added +19.9k |
| TOWERVIEW LLC 4.10% of their portfolio | 222.3k $6.3m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 207.8k $5.8m | Added +80.0k |
| Exome Asset Management LLC 3.55% of their portfolio | 204.4k $5.8m | Reduced -74.8k |
| HighVista Strategies LLC 1.28% of their portfolio | 200.0k $5.6m | Added +87.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 179.8k $5.1m | Reduced -59.4k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 174.9k $4.9m | Added +88.2k |
| Susquehanna Portfolio Strategies, LLC 0.08% of their portfolio | 172.8k $4.9m | Unchanged |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 162.6k $4.6m | Reduced -376.1k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 153.9k $4.3m | Reduced -8.3k |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 147.0k $4.1m | Reduced -22.5k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 146.4k $4.1m | Reduced -245 |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 138.4k $3.9m | Added +64.5k |
| MOORE CAPITAL MANAGEMENT, LP 0.09% of their portfolio | 136.8k $3.8m | Added +95.4k |
| Swiss National Bank 0.00% of their portfolio | 135.9k $3.8m | Added +8.1k |
| STEMPOINT CAPITAL LP 0.66% of their portfolio | 135.7k $3.8m | Reduced -323.4k |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.01% of their portfolio | 134.8k $3.8m | New |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 132.3k $3.7m | Added +49.7k |
| Quantinno Capital Management LP 0.00% of their portfolio | 131.1k $3.7m | Added +4.0k |
| Elmind Capital, LP 0.92% of their portfolio | 130.0k $3.7m | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 112.1k $3.2m | Added +30.1k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 110.1k $3.1m | Reduced -99.7k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 104.4k $2.3m | Added +36.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 100.2k $2.8m | Reduced -54.4k |
| Ghisallo Capital Management LLC 0.06% of their portfolio | 100.0k $2.8m | Unchanged |
| TD Asset Management Inc 0.00% of their portfolio | 97.0k $2.7m | Reduced -94.2k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 96.8k $2.7m | Added +12.5k |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 94.0k $2.6m | Added +27.9k |
| Harvest Investment Services, LLC 0.40% of their portfolio | 92.8k $2.6m | Reduced -7.1k |
| Caption Management, LLC 0.09% of their portfolio | 90.0k $2.5m | Added +70.0k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 84.1k $2.4m | Added +26.0k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 78.8k $2.2m | Reduced -2.0k |
| Ally Bridge Group (NY) LLC 2.77% of their portfolio | 76.5k $2.2m | Reduced -90.5k |
| Mariner, LLC 0.00% of their portfolio | 71.7k $2.0m | Reduced -1.4k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 58.7k $1.7m | Reduced -135.6k |
| ALGERT GLOBAL LLC 0.02% of their portfolio | 57.8k $1.6m | Reduced -100.1k |
| Legal & General Group Plc 0.00% of their portfolio | 54.9k $1.5m | Added +4.3k |
| ACT CAPITAL MANAGEMENT, LLC 0.95% of their portfolio | 51.6k $1.5m | Reduced -122.7k |
| VANGUARD ASSET MANAGEMENT, Ltd 0.00% of their portfolio | 50.6k $1.4m | Added +8.4k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 50.4k $1.4m | Added +5.9k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 49.8k $1.4m | Added +7.5k |
| Squarepoint Ops LLC 0.00% of their portfolio | 47.6k $1.3m | Reduced -66.6k |
| MetLife Investment Management, LLC 0.01% of their portfolio | 46.3k $1.3m | Added +8.8k |
| FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio | 43.1k $1.2m | New |
| Creative Planning 0.00% of their portfolio | 41.8k $1.2m | Added +735 |
| Handelsbanken Fonder AB 0.00% of their portfolio | 36.4k $1.0m | New |