GUARDANT HEALTH INC GH
COM · Common Stock · CUSIP 40131M109 · ISIN US40131M1099
American biotechnology company
- SectorHealth care
- IndustryServices-Medical Laboratories
- HeadquartersPalo Alto, CA
- Founded2012
- Websiteguardanthealth.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($92.1m this quarter). Holder counts are more reliable. Shares outstanding: 134.2m as of 2026-07-24, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $149.52. Options: 14 managers hold calls ($153.9m notional), 17 hold puts ($148.2m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 329 |
| Q4 2022 | 293 |
| Q1 2023 | 281 |
| Q2 2023 | 303 |
| Q3 2023 | 299 |
| Q4 2023 | 296 |
| Q1 2024 | 260 |
| Q2 2024 | 284 |
| Q3 2024 | 273 |
| Q4 2024 | 300 |
| Q1 2025 | 345 |
| Q2 2025 | 368 |
| Q3 2025 | 397 |
| Q4 2025 | 499 |
| Q1 2026 | 488 |
| Q2 2026 | 598 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 134 | 128 |
| Q4 2024 | 145 | 122 |
| Q1 2025 | 178 | 154 |
| Q2 2025 | 193 | 161 |
| Q3 2025 | 202 | 170 |
| Q4 2025 | 275 | 181 |
| Q1 2026 | 254 | 236 |
| Q2 2026 | 346 | 220 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $156.4m | $173.1m | 1.11 |
| Q4 2025 | $243.1m | $124.0m | 0.51 |
| Q1 2026 | $78.8m | $111.7m | 1.42 |
| Q2 2026 | $153.9m | $148.2m | 0.96 |
Biggest buyers
| JANE STREET GROUP, LLC | Added | +1.8m |
| AMERIPRISE FINANCIAL INC | Added | +1.7m |
| FMR LLC | Added | +1.4m |
| D. E. Shaw & Co., Inc. | Added | +828.2k |
| HRT FINANCIAL LP | New | +703.9k |
| MILLENNIUM MANAGEMENT LLC | Added | +701.1k |
| CITADEL ADVISORS LLC | Added | +673.6k |
| Artisan Partners Limited Partnership | Added | +664.4k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | +568.1k |
| Squarepoint Ops LLC | Added | +388.4k |
Biggest sellers
| BlackRock, Inc. | Reduced | -3.9m |
| BAILLIE GIFFORD & CO | Reduced | -1.6m |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | -987.3k |
| Alyeska Investment Group, L.P. | Reduced | -841.7k |
| T. Rowe Price Investment Management, Inc. | Reduced | -737.8k |
| GOLDMAN SACHS GROUP INC | Reduced | -659.9k |
| STATE STREET CORP | Reduced | -621.1k |
| UBS Group AG | Reduced | -539.8k |
| Invesco Ltd. | Reduced | -516.7k |
| ALLIANCEBERNSTEIN L.P. | Reduced | -510.4k |
Biggest calls
| JANE STREET GROUP, LLC | Added | $53.3m355.2k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $33.7m224.3k shares |
| CITADEL ADVISORS LLC | Reduced | $18.4m122.5k shares |
| GROUP ONE TRADING LLC | Added | $10.9m72.5k shares |
| MILLENNIUM MANAGEMENT LLC | Reduced | $9.4m62.7k shares |
| Walleye Trading LLC | Reduced | $7.0m46.7k shares |
| Squarepoint Ops LLC | New | $5.9m39.2k shares |
| IMC-Chicago, LLC | Added | $4.9m32.8k shares |
| Point72 Asset Management, L.P. | Reduced | $4.9m32.5k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.1m14.1k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $60.3m402.2k shares |
| Parallax Volatility Advisers, L.P. | Added | $28.5m190.0k shares |
| Portman Square Capital LLP | Reduced | $14.2m94.8k shares |
| CITADEL ADVISORS LLC | Added | $7.5m50.3k shares |
| JANE STREET GROUP, LLC | Reduced | $7.2m47.8k shares |
| SIMPLEX TRADING, LLC | Added | $5.1m33.7k shares |
| Squarepoint Ops LLC | New | $4.4m29.4k shares |
| IMC-Chicago, LLC | Added | $4.3m28.8k shares |
| CITIGROUP INC | New | $3.8m25.2k shares |
| Jefferies Financial Group Inc. | Reduced | $3.4m22.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution -2.3 pts · filed 2026-07-28 | 5.2% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.0% |
Fell to 5% or below in the last year: PRICE T ROWE ASSOCIATES INC /MD/ (4.9%, 2026-08-14), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 4 | $625.1k | $175.4k |
| Q1 2025 | 0 | — | 3 | $170.4k | $19.3k |
| Q2 2025 | 0 | — | 6 | $12.9m | $12.7m |
| Q3 2025 | 0 | — | 7 | $23.2m | $5.1m |
| Q4 2025 | 0 | — | 12 | $44.7m | $5.9m |
| Q1 2026 | 0 | — | 5 | $6.3m | $2.1m |
| Q2 2026 | 1 | $78.5k | 13 | $92.2m | $72.9m |
| Q3 2026 | 0 | — | 10 | $30.7m | $201.9k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-16 | Krognes Steve E. Director | Sold | $1.2m6.7k shares |
| 2026-09-16 | Azar Alex M II Director | Sold plan | $144.6k826 shares |
| 2026-09-16 | Tariq Musa Director | Sold plan | $20.3k116 shares |
| 2026-09-15 | Chudova Darya Chief Technology Officer | Sold | $1.4m7.7k shares |
| 2026-09-11 | Kalia Kumud Chief Information Officer | Sold | $632.2k4.0k shares |
| 2026-08-21 | Talasaz AmirAli Co-Chief Executive Officer, director · Shares held by the Talasaz Family Foundation | Sold | $6.3m37.5k shares |
| 2026-08-17 | Tariq Musa Director | Sold plan | $18.1k116 shares |
| 2026-08-12 | Monroe Terilyn J. Chief People Officer | Sold | $7.6m46.3k shares |
| 2026-08-10 | Freeman Chris Chief Commercial Officer | Sold | $10.8m63.6k shares |
| 2026-08-05 | Hidalgo Medina Manuel Director | Sold | $279.2k1.7k shares |
| 2026-08-04 | CLARK IAN T Director · By The Thornton-Clark Family Trust, J Thornton-Clark & I Clark TTE Account | Sold | $2.3m14.2k shares |
| 2026-07-16 | Tariq Musa Director | Sold plan | $18.9k116 shares |
| 2026-06-29 | Talasaz AmirAli Co-Chief Executive Officer, director · Shares held by Talasaz and Eskandari 2017 Family Trust | Sold plan | $21.7m143.0k shares |
| 2026-06-26 | Talasaz AmirAli Co-Chief Executive Officer, director · Shares held by Talasaz and Eskandari 2017 Family Trust | Sold plan | $17.6m117.0k shares |
| 2026-06-22 | Tariq Musa Director | Sold plan | $255.9k2.0k shares |
| 2026-06-22 | POTTER MYRTLE S Director | Sold plan | $204.1k1.6k shares |
| 2026-06-16 | Tariq Musa Director | Sold plan | $15.1k116 shares |
| 2026-06-15 | Kalia Kumud Chief Information Officer | Sold | $78.6k600 shares |
| 2026-06-15 | Kalia Kumud Chief Information Officer | Bought | $78.5k600 shares |
| 2026-06-11 | Kalia Kumud Chief Information Officer | Sold | $445.2k3.4k shares |
| 2026-06-10 | Kalia Kumud Chief Information Officer | Sold | $652.0k5.0k shares |
| 2026-06-10 | Kalia Kumud Chief Information Officer | Sold | $78.5k600 shares |
| 2026-06-05 | Eltoukhy Helmy Co-Chief Executive Officer, director · Shares held by Helmy A. Eltoukhy Revocable Trust | Sold | $12.6m100.0k shares |
| 2026-06-05 | Bell Michael Brian Chief Financial Officer | Sold | $257.2k2.0k shares |
| 2026-06-04 | Krognes Steve E. Director | Sold | $1.2m9.3k shares |
| 2026-06-03 | Joyce Meghan V. Director | Sold plan | $1.3m10.0k shares |
| 2026-05-28 | Hidalgo Medina Manuel Director | Sold | $130.1k1.0k shares |
| 2026-05-27 | Saia John G. Chief Legal Officer | Sold plan | $1.3m10.0k shares |
| 2026-05-22 | Freeman Chris Chief Commercial Officer | Sold | $2.9m24.4k shares |
| 2026-05-20 | Talasaz AmirAli Co-Chief Executive Officer, director · Shares held by Talasaz and Eskandari 2017 Family Trust | Sold plan | $23.1m210.0k shares |
The latest 30 of 37 trades.
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.02% of their portfolio | 7.6m $1.1bn | Reduced -3.9m |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.10% of their portfolio | 6.5m $977.4m | Reduced -508.7k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.02% of their portfolio | 5.8m $863.6m | Added +131.7k |
| FMR LLC 0.04% of their portfolio | 5.5m $823.4m | Added +1.4m |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.04% of their portfolio | 5.4m $817.0m | Reduced -392.2k |
| Invesco Ltd. 0.05% of their portfolio | 4.4m $664.6m | Reduced -516.7k |
| GOLDMAN SACHS GROUP INC 0.06% of their portfolio | 3.8m $566.5m | Reduced -659.9k |
| TWO SIGMA INVESTMENTS, LP 0.42% of their portfolio | 3.7m $558.0m | Reduced -510.2k |
| Capital International Investors 0.11% of their portfolio | 3.4m $510.0m | Reduced -81.7k |
| Deep Track Capital, LP 7.50% of their portfolio | 3.4m $509.1m | Added +55.1k |
| FRANKLIN RESOURCES INC 0.11% of their portfolio | 3.2m $485.5m | Reduced -212.1k |
| AMERIPRISE FINANCIAL INC 0.10% of their portfolio | 3.2m $472.8m | Added +1.7m |
| FULLER & THALER ASSET MANAGEMENT, INC. 1.07% of their portfolio | 2.6m $394.4m | Added +78.7k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 2.5m $378.4m | Reduced -987.3k |
| BAILLIE GIFFORD & CO 0.31% of their portfolio | 2.3m $342.7m | Reduced -1.6m |
| STATE STREET CORP 0.01% of their portfolio | 2.3m $339.6m | Reduced -621.1k |
| FEDERATED HERMES, INC. 0.43% of their portfolio | 2.0m $299.9m | Added +111.6k |
| EVENTIDE ASSET MANAGEMENT, LLC 3.93% of their portfolio | 2.0m $293.8m | Reduced -404.6k |
| LORD, ABBETT & CO. LLC 0.78% of their portfolio | 1.8m $272.1m | Reduced -85.6k |
| JANE STREET GROUP, LLC 0.17% of their portfolio | 1.8m $267.6m | Added +1.8m |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.80% of their portfolio | 1.6m $243.7m | Added +261.9k |
| MILLENNIUM MANAGEMENT LLC 0.16% of their portfolio | 1.6m $243.4m | Added +701.1k |
| NORGES BANK 0.02% of their portfolio | 1.5m $232.3m | Not comparable |
| Driehaus Capital Management LLC 1.33% of their portfolio | 1.5m $230.1m | Added +9.7k |
| RTW INVESTMENTS, LP 1.90% of their portfolio | 1.5m $222.2m | Unchanged |
| Artisan Partners Limited Partnership 0.36% of their portfolio | 1.5m $221.9m | Added +664.4k |
| CITADEL ADVISORS LLC 0.12% of their portfolio | 1.4m $217.5m | Added +673.6k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.04% of their portfolio | 1.4m $216.0m | Reduced -183.7k |
| Hood River Capital Management LLC 1.52% of their portfolio | 1.4m $209.3m | Added +85.2k |
| ALLIANCEBERNSTEIN L.P. 0.04% of their portfolio | 1.4m $128.9m | Reduced -510.4k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.16% of their portfolio | 1.4m $208.6m | Added +184.6k |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.59% of their portfolio | 1.3m $196.7m | Added +360.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.03% of their portfolio | 1.3m $190.3m | Reduced -183.2k |
| D. E. Shaw & Co., Inc. 0.12% of their portfolio | 1.3m $188.4m | Added +828.2k |
| MORGAN STANLEY 0.01% of their portfolio | 1.1m $163.3m | Reduced -398.8k |
| Temasek Holdings (Private) Ltd 0.42% of their portfolio | 1.0m $153.6m | Added +38.4k |
| Bank of New York Mellon Corp 0.02% of their portfolio | 994.7k $149.2m | Reduced -396.5k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 976.8k $146.5m | Added +81.6k |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 3.77% of their portfolio | 967.7k $145.2m | Added +104.8k |
| Point72 Asset Management, L.P. 0.21% of their portfolio | 920.8k $138.1m | Added +224.9k |
| UBS Group AG 0.02% of their portfolio | 866.0k $129.9m | Reduced -539.8k |
| VANGUARD FIDUCIARY TRUST CO 0.03% of their portfolio | 848.5k $127.3m | Reduced -41.5k |
| CADIAN CAPITAL MANAGEMENT, LP 8.60% of their portfolio | 757.4k $113.6m | Reduced -22.3k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 743.8k $111.6m | Reduced -368.7k |
| HRT FINANCIAL LP 0.25% of their portfolio | 703.9k $105.6m | New |
| Alyeska Investment Group, L.P. 0.25% of their portfolio | 647.8k $97.2m | Reduced -841.7k |
| Allspring Global Investments Holdings, LLC 0.17% of their portfolio | 646.5k $110.4m | Added +37.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.09% of their portfolio | 644.1k $96.6m | Added +568.1k |
| WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio | 621.5k $93.2m | Reduced -351.1k |
| AMERICAN CENTURY COMPANIES INC 0.04% of their portfolio | 608.7k $91.3m | Reduced -258.8k |
| ORBIMED ADVISORS LLC 1.66% of their portfolio | 583.7k $87.6m | Added +148.5k |
| Squarepoint Ops LLC 0.17% of their portfolio | 580.1k $87.0m | Added +388.4k |
| Erste Asset Management GmbH 0.69% of their portfolio | 577.3k $88.8m | Reduced -238.6k |
| SAMLYN CAPITAL, LLC 1.40% of their portfolio | 561.9k $84.3m | Added +312.7k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 549.1k $85.3m | Added +244.8k |
| ARK Investment Management LLC 0.49% of their portfolio | 506.4k $76.0m | Added +19.7k |
| VOYA INVESTMENT MANAGEMENT LLC 0.06% of their portfolio | 480.8k $72.1m | Reduced -24.2k |
| BROWN ADVISORY INC 0.10% of their portfolio | 445.6k $66.8m | Added +116.0k |
| Aristotle Atlantic Partners, LLC 2.75% of their portfolio | 442.8k $66.4m | Reduced -2.7k |
| First Light Asset Management, LLC 4.03% of their portfolio | 441.6k $66.3m | Added +161.3k |
| FRED ALGER MANAGEMENT, LLC 0.21% of their portfolio | 416.6k $62.5m | Reduced -205.7k |
| Sumitomo Mitsui Trust Group, Inc. 0.03% of their portfolio | 404.8k $60.7m | Reduced -79.0k |
| Amova Asset Management Americas, Inc. 0.78% of their portfolio | 403.8k $60.5m | Reduced -79.7k |
| VICTORY CAPITAL MANAGEMENT INC 0.03% of their portfolio | 392.0k $58.8m | Reduced -1.9k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.08% of their portfolio | 371.8k $55.8m | Reduced -444.3k |
| 1832 Asset Management L.P. 0.07% of their portfolio | 369.0k $55.4m | New |
| EMERALD ADVISERS, LLC 1.29% of their portfolio | 364.0k $54.6m | Reduced -477.9k |
| JENNISON ASSOCIATES LLC 0.03% of their portfolio | 356.0k $53.4m | Added +152.2k |
| SEI INVESTMENTS CO 0.05% of their portfolio | 346.4k $52.0m | Added +5.4k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.02% of their portfolio | 341.6k $51.2m | New |
| RAYMOND JAMES FINANCIAL INC 0.01% of their portfolio | 337.2k $50.6m | Reduced -1.2k |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.07% of their portfolio | 330.1k $49.5m | Added +95.8k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.28% of their portfolio | 322.2k $48.3m | Added +314.2k |
| Handelsbanken Fonder AB 0.13% of their portfolio | 301.0k $45.2m | Added +185.2k |
| Eagle Health Investments LP 7.48% of their portfolio | 300.7k $45.1m | Reduced -9.6k |
| Nuveen, LLC 0.01% of their portfolio | 289.3k $43.4m | Reduced -149.0k |
| Clearbridge Investments, LLC 0.03% of their portfolio | 280.3k $42.1m | New |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 274.1k $41.1m | Added +35.6k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.05% of their portfolio | 272.7k $40.9m | Added +123.1k |
| EMERALD MUTUAL FUND ADVISERS TRUST 1.43% of their portfolio | 271.4k $40.7m | Reduced -248.2k |
| ROYAL BANK OF CANADA 0.01% of their portfolio | 264.3k $39.6m | Added +117.9k |
| Stephens Investment Management Group LLC 0.41% of their portfolio | 254.3k $38.2m | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.06% of their portfolio | 250.0k $37.5m | Added +6.0k |
| Swiss National Bank 0.02% of their portfolio | 243.5k $36.5m | Added +21.4k |
| SEGALL BRYANT & HAMILL, LLC 0.42% of their portfolio | 236.3k $35.5m | Added +4.1k |
| RHUMBLINE ADVISERS 0.03% of their portfolio | 231.6k $34.7m | Added +73.7k |
| Sicart Associates LLC 8.49% of their portfolio | 231.0k $34.7m | Added +912 |
| California Public Employees Retirement System 0.02% of their portfolio | 228.9k $34.3m | Added +13.4k |
| Connor, Clark & Lunn Investment Management Ltd. 0.06% of their portfolio | 215.4k $32.3m | Reduced -39.4k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.02% of their portfolio | 210.5k $32.4m | Added +209.7k |
| Russell Investments Group, Ltd. 0.03% of their portfolio | 210.1k $31.5m | Added +21.9k |
| Science & Technology Partners, L.P. 5.28% of their portfolio | 208.8k $31.3m | New |
| NEXT CENTURY GROWTH INVESTORS LLC 1.60% of their portfolio | 200.7k $30.1m | Added +173.7k |
| TREMBLANT CAPITAL GROUP 0.85% of their portfolio | 197.8k $29.7m | New |
| PICTON MAHONEY ASSET MANAGEMENT 0.27% of their portfolio | 191.9k $28.8m | Reduced -58.1k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 185.4k $27.8m | Added +584 |
| MARSHALL WACE, LLP 0.02% of their portfolio | 185.2k $27.8m | New |
| Casdin Capital, LLC 1.39% of their portfolio | 185.0k $27.8m | Reduced -130.0k |
| Atika Capital Management LLC 2.69% of their portfolio | 181.0k $27.2m | Added +90.0k |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 179.5k $26.9m | Reduced -393.2k |