Vault-13

REVOLUTION MEDICINES INC RVMD

COM · Common Stock · CUSIP 76155X100 · ISIN US76155X1000

Company in Redwood City, United States

690 institutional holders +176 vs Q1 2026
213,814,172213.8m shares reported held*
99.8% of all shares outstanding*
$40.1bnreported value*
234 new 241 added 147 reduced 60 sold out net bought ≈ $2.7bn (+12.4m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($52.1m this quarter). Holder counts are more reliable. Shares outstanding: 214.3m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $187.58. Options: 27 managers hold calls ($741.6m notional), 22 hold puts ($391.4m).

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

0250500750Q3 22: 142Q4 22: 136Q1 23: 153Q2 23: 140Q3 23: 169Q4 23: 185Q1 24: 211Q2 24: 224Q3 24: 256Q4 24: 283Q1 25: 286Q2 25: 310Q3 25: 324Q4 25: 388Q1 26: 514Q2 26: 690690Q3 22Q3 23Q3 24Q3 25Q2 26
Numbers
QuarterHolders
Q3 2022142
Q4 2022136
Q1 2023153
Q2 2023140
Q3 2023169
Q4 2023185
Q1 2024211
Q2 2024224
Q3 2024256
Q4 2024283
Q1 2025286
Q2 2025310
Q3 2025324
Q4 2025388
Q1 2026514
Q2 2026690

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
5000500Q3 24: 142 bought or addedQ3 24: 85 cut or sold outQ4 24: 166 bought or addedQ4 24: 89 cut or sold outQ4 24Q1 25: 141 bought or addedQ1 25: 129 cut or sold outQ2 25: 169 bought or addedQ2 25: 124 cut or sold outQ2 25Q3 25: 181 bought or addedQ3 25: 132 cut or sold outQ4 25: 222 bought or addedQ4 25: 139 cut or sold outQ4 25Q1 26: 321 bought or addedQ1 26: 165 cut or sold outQ2 26: 475 bought or addedQ2 26: 207 cut or sold outQ2 26
Numbers
QuarterBought or addedCut or sold out
Q3 202414285
Q4 202416689
Q1 2025141129
Q2 2025169124
Q3 2025181132
Q4 2025222139
Q1 2026321165
Q2 2026475207

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$200m$400m$600m$800mQ3 25 calls: $128.5mQ3 25 puts: $47.0mQ3 25P/C 0.37Q4 25 calls: $243.0mQ4 25 puts: $38.2mQ4 25P/C 0.16Q1 26 calls: $326.4mQ1 26 puts: $519.4mQ1 26P/C 1.59Q2 26 calls: $741.6mQ2 26 puts: $391.4mQ2 26P/C 0.53
Numbers
QuarterCallsPutsP/C
Q3 2025$128.5m$47.0m0.37
Q4 2025$243.0m$38.2m0.16
Q1 2026$326.4m$519.4m1.59
Q2 2026$741.6m$391.4m0.53

Biggest buyers

Darwin Global Management, Ltd. Added +8,418,804+8.4m
Capital World Investors New +4,008,244+4.0m
FMR LLC Added +3,736,108+3.7m
JPMORGAN CHASE & CO Added +2,996,673+3.0m
BlackRock, Inc. Added +2,483,084+2.5m
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ New +2,012,317+2.0m
BAKER BROS. ADVISORS LP Added +1,888,000+1.9m
Nearwater Capital Markets, Ltd Added +1,419,000+1.4m
AQR CAPITAL MANAGEMENT LLC Added +1,178,663+1.2m
UBS Group AG Added +1,061,573+1.1m

Biggest sellers

ADAGE CAPITAL PARTNERS GP, L.L.C. Reduced -4,878,385-4.9m
WELLINGTON MANAGEMENT GROUP LLP Reduced -2,184,404-2.2m
Vestal Point Capital, LP Reduced -1,925,000-1.9m
Abu Dhabi Investment Council Co P.J.S.C Reduced -1,603,139-1.6m
Logos Global Management LP Reduced -1,300,000-1.3m
Alyeska Investment Group, L.P. Reduced -1,226,542-1.2m
Holocene Advisors, LP Reduced -1,109,375-1.1m
D. E. Shaw & Co., Inc. Reduced -1,009,898-1.0m
WESTFIELD CAPITAL MANAGEMENT CO LP Reduced -955,757-955.8k
PRICE T ROWE ASSOCIATES INC /MD/ Reduced -841,910-841.9k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $182.4m973.9k shares
Caption Management, LLC Added $126.9m677.8k shares
JANE STREET GROUP, LLC Added $97.9m522.7k shares
CITADEL ADVISORS LLC Added $85.2m454.9k shares
IMC-Chicago, LLC Added $48.8m260.6k shares
Caligan Partners LP Added $47.2m251.8k shares
JPMORGAN CHASE & CO New $40.8m211.8k shares
GROUP ONE TRADING LLC Added $25.9m138.5k shares
D. E. Shaw & Co., Inc. Added $16.8m89.6k shares
SIMPLEX TRADING, LLC Added $10.5m55.8k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $126.2m674.0k shares
Integral Health Asset Management, LLC Reduced $56.2m300.0k shares
Caption Management, LLC Reduced $37.3m199.2k shares
PEAK6 LLC New $36.5m194.8k shares
JANE STREET GROUP, LLC Reduced $32.8m175.3k shares
CITADEL ADVISORS LLC Reduced $31.4m167.6k shares
JPMORGAN CHASE & CO Reduced $14.8m76.8k shares
IMC-Chicago, LLC Reduced $13.4m71.6k shares
LMR Partners LLP Reduced $13.1m70.0k shares
D. E. Shaw & Co., Inc. Added $6.6m35.5k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Farallon Capital Partners, L.P. 13G · passive investor -0.4 pts · filed 2026-02-09 7.5% -0.4 pts 14.6m≈ $2.7bn 2026-02-09
FARALLON CAPITAL MANAGEMENT, L.L.C. 13G · institution filed 2026-08-13 6.4% 13.6m≈ $2.5bn 2026-08-13
BlackRock, Inc. 13G · institution +1.2 pts · filed 2026-07-29 5.7% +1.2 pts 12.2m≈ $2.3bn 2026-07-29
BAKER BROS. ADVISORS LP 13G · institution +0.4 pts · filed 2026-08-14 5.3% +0.4 pts 11.4m≈ $2.1bn 2026-08-14
Janus Henderson Group Ltd. 13G · institution +0.2 pts · filed 2026-08-13 5.1% +0.2 pts 10.7m≈ $2.0bn 2026-08-13

Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), WELLINGTON MANAGEMENT GROUP LLP (3.6%, 2026-02-10)

Insider purchases and sales since 1 Apr 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
10010Q4 24: 1 buyingQ4 24: 7 sellingQ1 25: 0 buyingQ1 25: 5 sellingQ1 25Q2 25: 0 buyingQ2 25: 6 sellingQ3 25: 0 buyingQ3 25: 6 sellingQ3 25Q4 25: 0 buyingQ4 25: 5 sellingQ1 26: 0 buyingQ1 26: 8 sellingQ1 26Q2 26: 0 buyingQ2 26: 7 sellingQ3 26: 0 buyingQ3 26: 9 sellingQ3 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20241$60.0m7$13.1m$13.1m
Q1 20250—5$1.0m$1.0m
Q2 20250—6$1.7m$1.7m
Q3 20250—6$7.4m$7.4m
Q4 20250—5$16.8m$16.8m
Q1 20260—8$19.0m$19.0m
Q2 20260—7$42.9m$42.2m
Q3 20260—9$76.7m$76.7m
DateInsiderTradeSharesPrice ValueTheir holding
2026-09-25 Mancini Anthony Officer Sold plan 3,121 $200.54 $625.9k3.1k shares -7%
2026-09-25 Cislini Jeff SVP & General Counsel Sold plan 765 $207.32 $158.6k765 shares -2%
2026-09-24 Mancini Anthony Officer Sold plan 587 $200.00 $117.4k587 shares -2%
2026-09-22 ANDERSON ELIZABETH M Director Sold plan 10,143 $193.04 $2.0m10.1k shares -70%
2026-09-18 Mancini Anthony Officer Sold plan 1,764 $196.94 $347.4k1.8k shares -4%
2026-09-16 GOLDSMITH MARK A Officer, director Sold plan 13,988 $199.23 $2.8m14.0k shares -5%
2026-09-16 Kelsey Stephen Michael Officer Sold plan 5,569 $199.23 $1.1m5.6k shares -2%
2026-09-16 Horn Margaret A Chief Operating Officer Sold plan 4,967 $199.23 $989.6k5.0k shares -3%
2026-09-16 Anders Jack Chief Financial Officer Sold plan 4,053 $199.24 $807.5k4.1k shares -3%
2026-09-16 Cislini Jeff SVP & General Counsel Sold plan 3,366 $199.23 $670.6k3.4k shares -6%
2026-09-16 Mancini Anthony Officer Sold plan 1,774 $199.24 $353.4k1.8k shares -4%
2026-09-16 Sandler Alan B. Chief Development Officer Sold plan 341 $199.24 $67.9k341 shares -1%
2026-09-11 Kelsey Stephen Michael Officer Sold plan 92,531 $202.36 $18.7m92.5k shares -24%
2026-09-10 Mancini Anthony Officer Sold plan 15,448 $204.16 $3.2m15.4k shares -26%
2026-09-08 Kim Lorence H. Director · Trust Sold plan 17,090 $209.82 $3.6m17.1k shares -100%
2026-08-31 Kim Lorence H. Director · Trust Sold plan 56,000 $203.24 $11.4m56.0k shares -77%
2026-08-21 GOLDSMITH MARK A Officer, director Sold plan 80,000 $209.20 $16.7m80.0k shares -23%
2026-08-21 Cislini Jeff General Counsel Sold plan 56,894 $209.24 $11.9m56.9k shares -50%
2026-08-21 GOLDSMITH MARK A Officer, director Sold plan 3,127 $209.31 $654.5k3.1k shares -5%
2026-08-21 GOLDSMITH MARK A Officer, director · Trust Sold plan 2,873 $209.08 $600.7k2.9k shares -4%
2026-06-29 Patel Sushil Director Sold plan 5,580 $187.99 $1.0m5.6k shares -20%
2026-06-24 Anders Jack Chief Financial Officer Sold plan 20,000 $168.33 $3.4m20.0k shares -14%
2026-06-17 Horn Margaret A Chief Operating Officer Sold plan 29,600 $160.12 $4.7m29.6k shares -16%
2026-06-16 GOLDSMITH MARK A Officer, director Sold plan 10,020 $156.12 $1.6m10.0k shares -4%
2026-06-16 Mancini Anthony Officer Sold 4,615 $156.12 $720.5k4.6k shares -8%
2026-06-16 Kelsey Stephen Michael Officer Sold plan 4,175 $156.12 $651.8k4.2k shares -1%
2026-06-16 Anders Jack Chief Financial Officer Sold plan 2,722 $156.12 $425.0k2.7k shares -2%
2026-06-16 Cislini Jeff General Counsel Sold plan 2,157 $156.12 $336.8k2.2k shares -4%
2026-06-15 Horn Margaret A Chief Operating Officer Sold plan 60,400 $160.17 $9.7m60.4k shares -28%
2026-06-11 Horn Margaret A Chief Operating Officer Sold plan 10,000 $148.01 $1.5m10.0k shares -6%

The latest 30 of 33 trades.

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 BlackRock, Inc. 0.04% of their portfolio New York, NY 13,695,79013.7m $2.6bn $2.6bn 0.04% Added +2.5m +2,483,084
2 FARALLON CAPITAL MANAGEMENT, L.L.C. 14.86% of their portfolio SAN FRANCISCO, CA 13,550,79613.6m $2.5bn $2.5bn 14.86% Reduced -54.0k -54,000
3 FMR LLC 0.10% of their portfolio BOSTON, MA 12,200,42212.2m $2.3bn $2.3bn 0.10% Added +3.7m +3,736,108
4 BAKER BROS. ADVISORS LP 10.74% of their portfolio NEW YORK, NY 11,443,35711.4m $2.1bn $2.1bn 10.74% Added +1.9m +1,888,000
5 Jupiter Topco LLC 0.82% of their portfolio NEW YORK, NY 10,736,14510.7m $2.0bn $2.0bn 0.82% First filing
6 Darwin Global Management, Ltd. 54.45% of their portfolio ST. HELIER, Y9 10,629,82210.6m $2.0bn $2.0bn 54.45% Added +8.4m +8,418,804
7 VANGUARD CAPITAL MANAGEMENT LLC 0.04% of their portfolio MALVERN, PA 9,088,6619.1m $1.7bn $1.7bn 0.04% Added +726.4k +726,377
8 VANGUARD PORTFOLIO MANAGEMENT LLC 0.07% of their portfolio MALVERN, PA 8,294,8558.3m $1.6bn $1.6bn 0.07% Added +792.2k +792,232
9 Nextech Invest Ltd. 67.55% of their portfolio Zurich, V8 7,601,0877.6m $1.4bn $1.4bn 67.55% Unchanged
10 Paradigm Biocapital Advisors LP 22.31% of their portfolio NEW YORK, NY 6,361,3236.4m $1.2bn $1.2bn 22.31% Reduced -294.4k -294,380
11 UBS Group AG 0.16% of their portfolio ZURICH, V8 5,448,3645.4m $1.0bn $1.0bn 0.16% Added +1.1m +1,061,573
12 STATE STREET CORP 0.03% of their portfolio BOSTON, MA 4,897,0514.9m $917.1m $917.1m 0.03% Added +494.4k +494,389
13 Capital World Investors 0.09% of their portfolio LOS ANGELES, CA 4,008,2444.0m $750.7m $750.7m 0.09% New
14 GEODE CAPITAL MANAGEMENT, LLC 0.04% of their portfolio BOSTON, MA 3,942,6763.9m $736.8m $736.8m 0.04% Added +604.5k +604,534
15 WELLINGTON MANAGEMENT GROUP LLP 0.12% of their portfolio Boston, MA 3,843,4153.8m $719.8m $719.8m 0.12% Reduced -2.2m -2,184,404
16 JPMORGAN CHASE & CO 0.04% of their portfolio NEW YORK, NY 3,298,0663.3m $636.9m $636.9m 0.04% Added +3.0m +2,996,673
17 BVF INC/IL 14.20% of their portfolio San Francisco, CA 2,965,1603.0m $555.3m $555.3m 14.20% Added +108.4k +108,378
18 Alphabet Inc. 0.56% of their portfolio Mountain View, CA 2,946,6192.9m $551.8m $551.8m 0.56% Reduced -345.9k -345,906
19 Casdin Capital, LLC 24.16% of their portfolio New York, NY 2,577,3332.6m $482.7m $482.7m 24.16% Unchanged
20 DEERFIELD MANAGEMENT COMPANY, L.P. 4.67% of their portfolio New York, NY 2,392,0002.4m $448.0m $448.0m 4.67% Added +95.0k +95,000
21 PRICE T ROWE ASSOCIATES INC /MD/ 0.04% of their portfolio BALTIMORE, MD 2,390,3032.4m $447.7m $447.7m 0.04% Reduced -841.9k -841,910
22 Avoro Capital Advisors LLC 3.86% of their portfolio NEW YORK, NY 2,297,0002.3m $430.2m $430.2m 3.86% Reduced -47.4k -47,444
23 NORGES BANK 0.04% of their portfolio OSLO, Q8 2,157,4792.2m $404.1m $404.1m 0.04% Not comparable
24 GOLDMAN SACHS GROUP INC 0.04% of their portfolio NEW YORK, NY 2,133,1012.1m $399.5m $399.5m 0.04% Reduced -52.4k -52,399
25 Nearwater Capital Markets, Ltd 6.77% of their portfolio NEW YORK, NY 2,097,0002.1m $392.7m $392.7m 6.77% Added +1.4m +1,419,000
26 MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.12% of their portfolio Boston, MA 2,012,3172.0m $376.8m $376.8m 0.12% New
27 Woodline Partners LP 1.16% of their portfolio San Francisco, CA 2,002,8632.0m $375.1m $375.1m 1.16% Reduced -503.7k -503,707
28 Caligan Partners LP 17.73% of their portfolio NEW YORK, NY 1,961,7952.0m $367.4m $367.4m 17.73% Added +309.0k +308,987
29 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.05% of their portfolio SAN FRANCISCO, CA 1,917,0251.9m $359.0m $359.0m 0.05% Added +181.5k +181,549
30 Integral Health Asset Management, LLC 11.53% of their portfolio New York, NY 1,500,0001.5m $280.9m $280.9m 11.53% Unchanged
31 FRANKLIN RESOURCES INC 0.06% of their portfolio San Mateo, CA 1,488,3941.5m $278.7m $278.7m 0.06% Added +354.8k +354,848
32 Holocene Advisors, LP 0.58% of their portfolio New York, NY 1,359,2691.4m $254.6m $254.6m 0.58% Reduced -1.1m -1,109,375
33 AQR CAPITAL MANAGEMENT LLC 0.08% of their portfolio Greenwich, CT 1,295,4501.3m $242.6m $242.6m 0.08% Added +1.2m +1,178,663
34 VANGUARD FIDUCIARY TRUST CO 0.05% of their portfolio MALVERN, PA 1,291,1411.3m $241.8m $241.8m 0.05% Added +157.8k +157,822
35 NORTHERN TRUST CORP 0.02% of their portfolio CHICAGO, IL 1,117,1101.1m $209.2m $209.2m 0.02% Added +162.9k +162,854
36 Rock Springs Capital Management LP 10.10% of their portfolio Baltimore, MD 1,105,2101.1m $207.0m $207.0m 10.10% Reduced -104.3k -104,255
37 NATIONAL BANK OF CANADA /FI/ 0.18% of their portfolio MONTREAL, A8 1,096,0251.1m $205.3m $205.3m 0.18% Reduced -653.0k -652,975
38 Bellevue Group AG 4.13% of their portfolio ZURICH, V8 1,048,0141.0m $196.3m $196.3m 4.13% Reduced -496.4k -496,442
39 AMERIPRISE FINANCIAL INC 0.04% of their portfolio MINNEAPOLIS, MN 1,039,7021.0m $194.7m $194.7m 0.04% Reduced -540.1k -540,091
40 Pictet Asset Management Holding SA 0.18% of their portfolio CAROUGE, V8 1,014,8941.0m $190.8m $190.8m 0.18% Added +457.3k +457,334
41 BANK OF AMERICA CORP /DE/ 0.01% of their portfolio CHARLOTTE, NC 983,911983.9k $184.3m $184.3m 0.01% Added +369.8k +369,754
42 a16z Capital Management, L.L.C. 1.21% of their portfolio MENLO PARK, CA 921,099921.1k $172.5m $172.5m 1.21% Unchanged
43 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.03% of their portfolio NEW YORK, NY 912,335912.3k $170.9m $170.9m 0.03% Added +411.7k +411,740
44 Siren, L.L.C. 3.42% of their portfolio New York, NY 900,000900.0k $168.6m $168.6m 3.42% Reduced -211.0k -210,980
45 DEUTSCHE BANK AG\ 0.05% of their portfolio FRANKFURT AM MAIN, 2M 888,019888.0k $166.3m $166.3m 0.05% Added +422.3k +422,261
46 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 838,249838.2k $157.0m $157.0m 0.01% Added +132.5k +132,456
47 LORD, ABBETT & CO. LLC 0.42% of their portfolio JERSEY CITY, NJ 789,241789.2k $147.8m $147.8m 0.42% Added +655.0k +655,008
48 DIMENSIONAL FUND ADVISORS LP 0.03% of their portfolio AUSTIN, TX 763,434763.4k $143.1m $143.1m 0.03% Reduced -81.2k -81,180
49 TWO SIGMA INVESTMENTS, LP 0.10% of their portfolio NEW YORK, NY 737,697737.7k $138.2m $138.2m 0.10% Reduced -821.1k -821,110
50 Logos Global Management LP 5.64% of their portfolio San Francisco, CA 700,000700.0k $131.1m $131.1m 5.64% Reduced -1.3m -1,300,000
51 Polar Capital Holdings Plc 0.37% of their portfolio London, X0 690,316690.3k $129.3m $129.3m 0.37% Reduced -443.6k -443,614
52 Alyeska Investment Group, L.P. 0.32% of their portfolio CHICAGO, IL 659,279659.3k $123.5m $123.5m 0.32% Reduced -1.2m -1,226,542
53 Bank of New York Mellon Corp 0.02% of their portfolio NEW YORK, NY 601,056601.1k $112.6m $112.6m 0.02% Reduced -34.3k -34,310
54 WESTFIELD CAPITAL MANAGEMENT CO LP 0.37% of their portfolio BOSTON, MA 600,821600.8k $112.5m $112.5m 0.37% Reduced -955.8k -955,757
55 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.16% of their portfolio Boston, MA 597,226597.2k $111.8m $111.8m 0.16% Reduced -4.9m -4,878,385
56 CITADEL ADVISORS LLC 0.06% of their portfolio MIAMI, FL 589,906589.9k $110.5m $110.5m 0.06% Added +189.9k +189,853
57 T. Rowe Price Investment Management, Inc. 0.07% of their portfolio BALTIMORE, MD 579,382579.4k $108.5m $108.5m 0.07% Reduced -84.7k -84,665
58 Invesco Ltd. 0.01% of their portfolio ATLANTA, GA 578,287578.3k $108.3m $108.3m 0.01% Added +185.4k +185,443
59 DAFNA Capital Management LLC 20.09% of their portfolio LOS ANGELES, CA 562,630562.6k $105.4m $105.4m 20.09% Reduced -18.0k -18,048
60 Candriam S.C.A. 0.47% of their portfolio STRASSEN, N4 556,392556.4k $104.1m $104.1m 0.47% Reduced -24.3k -24,285
61 BNP PARIBAS FINANCIAL MARKETS 0.05% of their portfolio PARIS, I0 552,710552.7k $103.5m $103.5m 0.05% Added +130.3k +130,267
62 MIC Capital Management UK LLP 25.25% of their portfolio LONDON, X0 531,733531.7k $99.6m $99.6m 25.25% Reduced -264.0k -264,000
63 PERCEPTIVE ADVISORS LLC 1.53% of their portfolio NEW YORK, NY 527,600527.6k $98.8m $98.8m 1.53% Added +269.0k +269,000
64 Boxer Capital Management, LLC 7.05% of their portfolio San Diego, CA 500,000500.0k $93.6m $93.6m 7.05% Unchanged
65 MPM BIOIMPACT LLC 5.62% of their portfolio BOSTON, MA 492,483492.5k $92.2m $92.2m 5.62% Reduced -14.3k -14,293
66 Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 4.91% of their portfolio WARSZAWA, R9 479,080479.1k $89.7m $89.7m 4.91% Unchanged
67 Nuveen, LLC 0.02% of their portfolio CHARLOTTE, NC 475,231475.2k $89.0m $89.0m 0.02% Added +134.6k +134,620
68 BOOTHBAY FUND MANAGEMENT, LLC 1.64% of their portfolio NEW YORK, NY 465,787465.8k $87.2m $87.2m 1.64% Added +27.2k +27,192
69 Swiss National Bank 0.04% of their portfolio ZURICH, V8 456,331456.3k $85.5m $85.5m 0.04% Added +30.9k +30,900
70 Vestal Point Capital, LP 1.97% of their portfolio NEW YORK, NY 450,000450.0k $84.3m $84.3m 1.97% Reduced -1.9m -1,925,000
71 First Turn Management, LLC 8.32% of their portfolio DEL MAR, CA 415,307415.3k $77.8m $77.8m 8.32% Reduced -53.1k -53,069
72 Checkpoint Capital L.P. 19.72% of their portfolio SAN FRANCISCO, CA 410,353410.4k $76.9m $76.9m 19.72% Added +147.8k +147,814
73 Assenagon Asset Management S.A. 0.05% of their portfolio SENNINGERBERG, N4 400,972401.0k $75.1m $75.1m 0.05% New
74 Duquesne Family Office LLC 1.72% of their portfolio New York, NY 399,587399.6k $74.8m $74.8m 1.72% Added +83.7k +83,727
75 Legal & General Group Plc 0.01% of their portfolio London, X0 381,366381.4k $71.4m $71.4m 0.01% Added +40.2k +40,218
76 GENERAL ATLANTIC, L.P. 2.31% of their portfolio New York, NY 357,791357.8k $67.0m $67.0m 2.31% Reduced -350.0k -350,000
77 California Public Employees Retirement System 0.04% of their portfolio Sacramento, CA 349,929349.9k $65.5m $65.5m 0.04% Added +68.0k +67,969
78 Mass General Brigham, Inc 17.85% of their portfolio SOMERVILLE, MA 344,091344.1k $64.4m $64.4m 17.85% Unchanged
79 TCG Crossover Management, LLC 1.53% of their portfolio PALO ALTO, CA 340,899340.9k $63.8m $63.8m 1.53% Reduced -235.6k -235,574
80 Qube Research & Technologies Ltd 0.07% of their portfolio LONDON, X0 314,365314.4k $58.9m $58.9m 0.07% Reduced -238.9k -238,925
81 1832 Asset Management L.P. 0.07% of their portfolio TORONTO, A6 309,200309.2k $57.9m $57.9m 0.07% New
82 Sumitomo Mitsui Trust Group, Inc. 0.03% of their portfolio CHIYODA-KU, TOKYO, M0 306,300306.3k $57.4m $57.4m 0.03% Added +35.3k +35,328
83 AIHC Capital Management Ltd 54.46% of their portfolio CENTRAL, K3 303,133303.1k $56.8m $56.8m 54.46% Reduced -525.8k -525,841
84 JENNISON ASSOCIATES LLC 0.03% of their portfolio NEW YORK, NY 280,933280.9k $52.6m $52.6m 0.03% Reduced -26.4k -26,444
85 Patient Square Capital LP 8.01% of their portfolio MENLO PARK, CA 276,000276.0k $51.7m $51.7m 8.01% New
86 National Pension Service 0.03% of their portfolio JEONJU-SI, JEOLLABUK-DO, M5 273,604273.6k $51.2m $51.2m 0.03% New
87 Amundi 0.01% of their portfolio Paris, I0 269,701269.7k $50.5m $50.5m 0.01% Added +131.1k +131,141
88 BAILLIE GIFFORD & CO 0.04% of their portfolio EDINBURGH, X0 263,466263.5k $49.3m $49.3m 0.04% Added +76.4k +76,394
89 FRED ALGER MANAGEMENT, LLC 0.16% of their portfolio NEW YORK, NY 259,468259.5k $48.6m $48.6m 0.16% Added +238.1k +238,094
90 Chicago Capital, LLC 1.14% of their portfolio Chicago, IL 251,847251.8k $47.2m $47.2m 1.14% New
91 Affinity Asset Advisors, LLC 2.29% of their portfolio NEW YORK, NY 250,000250.0k $46.8m $46.8m 2.29% Added +150.0k +150,000
92 CITIGROUP INC 0.02% of their portfolio NEW YORK, NY 247,052247.1k $46.3m $46.3m 0.02% Added +157.3k +157,310
93 Nicholas Investment Partners, LP 2.58% of their portfolio RANCHO SANTA FE, CA 244,594244.6k $45.8m $45.8m 2.58% Reduced -16.6k -16,572
94 MARSHALL WACE, LLP 0.04% of their portfolio LONDON, X0 244,544244.5k $45.8m $45.8m 0.04% Added +27.9k +27,883
95 Seven Fleet Capital Management LP 7.48% of their portfolio MOUNTAIN VIEW, CA 242,029242.0k $45.3m $45.3m 7.48% Added +161.2k +161,237
96 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.04% of their portfolio WEST SACRAMENTO, CA 238,463238.5k $44.7m $44.7m 0.04% Added +73.2k +73,186
97 VICTORY CAPITAL MANAGEMENT INC 0.02% of their portfolio San Antonio, TX 230,909230.9k $43.2m $43.2m 0.02% Added +88.3k +88,331
98 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.04% of their portfolio BALA CYNWYD, PA 227,985228.0k $42.7m $42.7m 0.04% Added +176.6k +176,600
99 EVENTIDE ASSET MANAGEMENT, LLC 0.57% of their portfolio Boston, MA 227,845227.8k $42.7m $42.7m 0.57% Reduced -33.6k -33,580
100 ROYAL BANK OF CANADA 0.01% of their portfolio TORONTO, A6 226,210226.2k $42.4m $42.4m 0.01% Reduced -145.5k -145,533