DIANTHUS THERAPEUTICS INC DNTH
COM · Common Stock · CUSIP 252828108
Biotechnology company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersNew York, NY
- Websitemagentatx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.5m this quarter). Holder counts are more reliable. Shares outstanding: 55.9m as of 2026-08-03, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $97.32. Options: 6 managers hold calls ($24.8m notional), 6 hold puts ($24.0m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2023 | 31 |
| Q4 2023 | 40 |
| Q1 2024 | 77 |
| Q2 2024 | 75 |
| Q3 2024 | 92 |
| Q4 2024 | 97 |
| Q1 2025 | 100 |
| Q2 2025 | 104 |
| Q3 2025 | 140 |
| Q4 2025 | 166 |
| Q1 2026 | 241 |
| Q2 2026 | 270 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 54 | 26 |
| Q4 2024 | 49 | 37 |
| Q1 2025 | 44 | 41 |
| Q2 2025 | 48 | 53 |
| Q3 2025 | 94 | 47 |
| Q4 2025 | 117 | 44 |
| Q1 2026 | 172 | 74 |
| Q2 2026 | 175 | 102 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $15.6m | $14.3m | 0.92 |
| Q4 2025 | $914.9k | $3.0m | 3.31 |
| Q1 2026 | $19.7m | $22.3m | 1.14 |
| Q2 2026 | $24.8m | $24.0m | 0.97 |
Biggest buyers
| T. Rowe Price Investment Management, Inc. | Added | +2.6m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +1.4m |
| STATE STREET CORP | Added | +958.5k |
| BlackRock, Inc. | Added | +948.1k |
| WELLINGTON MANAGEMENT GROUP LLP | Added | +634.1k |
| Assenagon Asset Management S.A. | New | +561.3k |
| JENNISON ASSOCIATES LLC | Added | +536.6k |
| FMR LLC | Added | +432.2k |
| Logos Global Management LP | Added | +400.0k |
| UBS Group AG | Added | +359.0k |
Biggest sellers
| RA CAPITAL MANAGEMENT, L.P. | Sold out | -2.6m |
| Avidity Partners Management LP | Reduced | -2.1m |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | Sold out | -836.0k |
| Point72 Asset Management, L.P. | Sold out | -643.6k |
| CITADEL ADVISORS LLC | Reduced | -635.6k |
| Catalio Capital Management, LP | Reduced | -527.4k |
| Balyasny Asset Management L.P. | Reduced | -312.1k |
| Sio Capital Management, LLC | Reduced | -310.8k |
| BRAIDWELL LP | Reduced | -304.8k |
| SILVERARC CAPITAL MANAGEMENT, LLC | Reduced | -264.7k |
Biggest calls
| Caption Management, LLC | Unchanged | $10.1m103.9k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $9.1m93.7k shares |
| JANE STREET GROUP, LLC | Added | $4.5m46.0k shares |
| CITADEL ADVISORS LLC | Added | $740.8k7.6k shares |
| GROUP ONE TRADING LLC | Unchanged | $243.7k2.5k shares |
| SIMPLEX TRADING, LLC | New | $39.0k400 shares |
Biggest puts
| Caption Management, LLC | Added | $7.5m77.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $7.1m73.0k shares |
| CITADEL ADVISORS LLC | Added | $4.2m43.4k shares |
| JANE STREET GROUP, LLC | Added | $4.0m40.9k shares |
| SIMPLEX TRADING, LLC | Added | $584.9k6.0k shares |
| GROUP ONE TRADING LLC | Reduced | $536.1k5.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +1.0 pts · filed 2025-11-05 | 15.0% |
| T. Rowe Price Investment Management, Inc. 13G · institution +5.0 pts · filed 2026-08-07 | 12.1% |
| BlackRock, Inc. 13G · institution +1.3 pts · filed 2026-07-28 | 6.4% |
| WELLINGTON MANAGEMENT GROUP LLP 13G · institution +1.1 pts · filed 2026-08-13 | 5.9% |
Fell to 5% or below in the last year: Sirenia Capital Management LP (3.1%, 2026-08-14), Point72 Asset Management, L.P. (1.2%, 2026-05-15), RA CAPITAL MANAGEMENT, L.P. (4.8%, 2026-05-15), Octagon Capital Advisors LP (3.6%, 2026-05-14), Fairmount Funds Management LLC (4.9%, 2025-11-25), Avidity Partners Management LP (4.9%, 2025-11-19), Deep Track Capital, LP (0.0%, 2025-11-14), BCLS Fund III Investments, LP (3.1%, 2025-11-14), Vestal Point Capital, LP (3.0%, 2025-11-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 1 | $700.0k | $700.0k |
| Q4 2025 | 0 | — | 2 | $8.3m | $8.3m |
| Q1 2026 | 0 | — | 5 | $28.0m | $28.0m |
| Q2 2026 | 0 | — | 4 | $5.6m | $5.6m |
| Q3 2026 | 0 | — | 7 | $29.3m | $29.3m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-17 | CARR EDWARD CHIEF ACCOUNTING OFFICER | Sold plan | $2.0m20.0k shares |
| 2026-09-01 | Randhawa Simrat EVP, Head of R&D | Sold plan | $2.5m23.1k shares |
| 2026-08-19 | Read Simon Director | Sold plan | $326.6k2.8k shares |
| 2026-08-10 | Veness Adam M SVP, General Counsel and Sec. | Sold plan | $1.8m16.2k shares |
| 2026-08-10 | McGeorge Anne Director | Sold plan | $844.8k7.8k shares |
| 2026-08-10 | Read Simon Director | Sold plan | $304.2k2.8k shares |
| 2026-08-07 | Garcia Marino CEO AND PRESIDENT, director | Sold plan | $17.9m166.0k shares |
| 2026-08-07 | Veness Adam M SVP, General Counsel and Sec. | Sold plan | $424.3k3.8k shares |
| 2026-07-09 | Savitz Ryan EVP, CFO & CBO | Sold plan | $3.2m31.2k shares |
| 2026-06-17 | Veness Adam M SVP, General Counsel and Sec. | Sold plan | $2.4m30.0k shares |
| 2026-06-01 | Randhawa Simrat EVP, Head of R&D | Sold plan | $2.4m26.5k shares |
| 2026-05-08 | Soteropoulos Paula Director | Sold plan | $51.2k599 shares |
| 2026-04-09 | Savitz Ryan EVP, CFO & CBO | Sold plan | $738.8k8.2k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.03% of their portfolio | 8.2m $799.3m | Added +432.2k |
| BlackRock, Inc. 0.01% of their portfolio | 4.1m $402.0m | Added +948.1k |
| T. Rowe Price Investment Management, Inc. 0.25% of their portfolio | 3.9m $379.0m | Added +2.6m |
| WELLINGTON MANAGEMENT GROUP LLP 0.05% of their portfolio | 3.2m $314.8m | Added +634.1k |
| Fairmount Funds Management LLC 16.35% of their portfolio | 2.5m $247.3m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio | 2.5m $245.2m | Added +1.4m |
| STATE STREET CORP 0.01% of their portfolio | 2.4m $229.8m | Added +958.5k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.2m $210.5m | Added +128.3k |
| Avidity Partners Management LP 32.85% of their portfolio | 2.1m $205.1m | Reduced -2.1m |
| Octagon Capital Advisors LP 16.48% of their portfolio | 1.8m $179.5m | Reduced -105.0k |
| TCG Crossover Management, LLC 3.93% of their portfolio | 1.7m $163.4m | Unchanged |
| FRED ALGER MANAGEMENT, LLC 0.42% of their portfolio | 1.3m $127.0m | Added +140.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 1.3m $122.7m | Added +342.3k |
| Venrock Adviser, LLC 3.49% of their portfolio | 1.2m $115.0m | Unchanged |
| UBS Group AG 0.02% of their portfolio | 1.1m $111.2m | Added +359.0k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 1.14% of their portfolio | 1.1m $109.7m | Added +105.5k |
| JENNISON ASSOCIATES LLC 0.06% of their portfolio | 1.0m $99.6m | Added +536.6k |
| Polar Capital Holdings Plc 0.28% of their portfolio | 1.0m $99.3m | Reduced -57.3k |
| CITADEL ADVISORS LLC 0.05% of their portfolio | 974.9k $95.0m | Reduced -635.6k |
| FRANKLIN RESOURCES INC 0.02% of their portfolio | 969.0k $94.5m | Added +801 |
| BAKER BROS. ADVISORS LP 0.42% of their portfolio | 852.2k $83.1m | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.02% of their portfolio | 834.1k $70.0m | Reduced -91.9k |
| Logos Global Management LP 3.36% of their portfolio | 800.0k $78.0m | Added +400.0k |
| Cormorant Asset Management, LP 3.75% of their portfolio | 750.0k $73.1m | Reduced -200.0k |
| BRAIDWELL LP 2.14% of their portfolio | 594.6k $58.0m | Reduced -304.8k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 570.1k $55.6m | Added +220.7k |
| Assenagon Asset Management S.A. 0.04% of their portfolio | 561.3k $54.7m | New |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 532.0k $51.9m | Added +102.9k |
| Woodline Partners LP 0.15% of their portfolio | 500.5k $48.8m | Added +67.1k |
| BARCLAYS PLC 0.01% of their portfolio | 431.8k $42.1m | Added +52.1k |
| LORD, ABBETT & CO. LLC 0.12% of their portfolio | 422.2k $41.2m | Added +123.0k |
| MPM BIOIMPACT LLC 2.50% of their portfolio | 420.0k $40.9m | Reduced -4.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 411.8k $40.1m | Added +108.0k |
| Affinity Asset Advisors, LLC 1.91% of their portfolio | 400.0k $39.0m | Added +50.0k |
| SILVERARC CAPITAL MANAGEMENT, LLC 4.23% of their portfolio | 390.0k $38.0m | Reduced -264.7k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 382.2k $37.3m | Reduced -165.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 366.0k $35.7m | Added +60.5k |
| Bain Capital Life Sciences Investors, LLC 2.10% of their portfolio | 362.5k $35.3m | Unchanged |
| Spruce Street Capital LP 6.79% of their portfolio | 354.8k $34.6m | Reduced -18.5k |
| Vivo Capital, LLC 3.15% of their portfolio | 354.0k $34.5m | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 321.5k $31.3m | Reduced -3.9k |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.10% of their portfolio | 314.9k $30.7m | New |
| VANGUARD FIDUCIARY TRUST CO 0.01% of their portfolio | 302.5k $29.5m | Added +52.8k |
| Driehaus Capital Management LLC 0.17% of their portfolio | 295.3k $28.8m | Reduced -22.0k |
| First Turn Management, LLC 2.98% of their portfolio | 285.8k $27.9m | Added +64.8k |
| TANG CAPITAL MANAGEMENT LLC 1.17% of their portfolio | 264.7k $25.8m | Unchanged |
| Artisan Partners Limited Partnership 0.04% of their portfolio | 258.3k $25.2m | Reduced -123.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 256.8k $25.0m | Added +68.1k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 256.4k $25.0m | Added +68.0k |
| RTW INVESTMENTS, LP 0.21% of their portfolio | 248.1k $24.2m | Unchanged |
| EMERALD ADVISERS, LLC 0.57% of their portfolio | 247.8k $24.2m | New |
| Pictet Asset Management Holding SA 0.02% of their portfolio | 247.3k $24.1m | Added +242.4k |
| TD Asset Management Inc 0.02% of their portfolio | 225.3k $22.0m | Added +108.8k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.29% of their portfolio | 225.3k $22.0m | Unchanged |
| LMR Partners LLP 0.16% of their portfolio | 224.0k $21.8m | Added +107.6k |
| Candriam S.C.A. 0.09% of their portfolio | 204.2k $19.9m | Reduced -9.3k |
| STEMPOINT CAPITAL LP 3.39% of their portfolio | 200.9k $19.6m | Added +29.8k |
| Qube Research & Technologies Ltd 0.02% of their portfolio | 196.9k $19.2m | Added +166.6k |
| SAMLYN CAPITAL, LLC 0.32% of their portfolio | 196.3k $19.1m | Reduced -234.8k |
| Nicholas Investment Partners, LP 1.03% of their portfolio | 186.8k $18.2m | Added +135.5k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.03% of their portfolio | 185.0k $18.0m | Added +25.0k |
| Ensign Peak Advisors, Inc 0.03% of their portfolio | 174.2k $17.0m | Reduced -30.1k |
| TimesSquare Capital Management, LLC 0.24% of their portfolio | 166.4k $16.2m | New |
| Atika Capital Management LLC 1.60% of their portfolio | 165.0k $16.1m | Added +36.2k |
| Artia Global Partners LP 3.02% of their portfolio | 163.0k $15.9m | Unchanged |
| Balyasny Asset Management L.P. 0.03% of their portfolio | 162.0k $15.8m | Reduced -312.1k |
| NEUBERGER BERMAN GROUP LLC 0.01% of their portfolio | 157.6k $15.4m | Added +98.5k |
| Alyeska Investment Group, L.P. 0.04% of their portfolio | 150.6k $14.7m | Added +98.3k |
| Russell Investments Group, Ltd. 0.01% of their portfolio | 143.4k $14.0m | Added +14.4k |
| Eagle Health Investments LP 2.12% of their portfolio | 131.3k $12.8m | New |
| EMERALD MUTUAL FUND ADVISERS TRUST 0.45% of their portfolio | 131.0k $12.8m | New |
| MARSHALL WACE, LLP 0.01% of their portfolio | 128.7k $12.5m | Reduced -213.2k |
| PFM Health Sciences, LP 1.03% of their portfolio | 121.2k $11.8m | Reduced -50.9k |
| Tri Locum Partners LP 1.45% of their portfolio | 120.7k $11.8m | Reduced -24.8k |
| Nuveen, LLC 0.00% of their portfolio | 119.5k $11.6m | Reduced -98.0k |
| ORBIMED ADVISORS LLC 0.21% of their portfolio | 115.0k $11.2m | New |
| Patient Square Capital LP 1.63% of their portfolio | 108.0k $10.5m | Added +14.1k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 107.5k $10.5m | New |
| MORGAN STANLEY 0.00% of their portfolio | 106.4k $10.4m | Added +8.9k |
| SEVEN GRAND MANAGERS, LLC 0.39% of their portfolio | 100.0k $9.7m | Unchanged |
| FIRST TRUST ADVISORS LP 0.01% of their portfolio | 94.2k $9.2m | New |
| SEI INVESTMENTS CO 0.01% of their portfolio | 92.3k $9.0m | Added +51 |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 91.8k $9.0m | Reduced -170.1k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 88.3k $8.6m | Added +72.7k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 87.9k $8.6m | Added +8.8k |
| Rhenman & Partners Asset Management AB 0.79% of their portfolio | 86.1k $8.4m | Added +4.5k |
| Invesco Ltd. 0.00% of their portfolio | 85.6k $8.3m | Reduced -45.1k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 75.4k $7.3m | Added +15.0k |
| Moody Aldrich Partners LLC 1.31% of their portfolio | 74.6k $7.3m | Reduced -7.6k |
| Swiss National Bank 0.00% of their portfolio | 73.8k $7.2m | Added +4.8k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 69.8k $6.8m | Added +38.3k |
| MERCER GLOBAL ADVISORS INC /ADV 0.01% of their portfolio | 65.7k $6.4m | New |
| LPL Financial LLC 0.00% of their portfolio | 65.3k $6.4m | Added +24.5k |
| Seven Fleet Capital Management LP 1.04% of their portfolio | 64.7k $6.3m | Reduced -16.1k |
| SummitTX Capital, L.P. 0.16% of their portfolio | 63.9k $6.2m | Reduced -36.2k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 62.8k $6.1m | Reduced -2.4k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.01% of their portfolio | 60.0k $5.9m | Added +12.1k |
| Sio Capital Management, LLC 0.99% of their portfolio | 59.3k $5.8m | Reduced -310.8k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 58.5k $5.7m | Added +13.3k |
| Jones Hill Capital LP 1.18% of their portfolio | 57.1k $5.6m | New |