VISTAGEN THERAPEUTICS INC VTGN
COM · Common Stock · CUSIP 92840H400
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $0.22. Options: 9 managers hold calls ($333.1k notional), 5 hold puts ($32.4k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q2 2023 | 33 |
| Q3 2023 | 35 |
| Q4 2023 | 46 |
| Q1 2024 | 42 |
| Q2 2024 | 43 |
| Q3 2024 | 48 |
| Q4 2024 | 55 |
| Q1 2025 | 49 |
| Q2 2025 | 52 |
| Q3 2025 | 58 |
| Q4 2025 | 55 |
| Q1 2026 | 56 |
| Q2 2026 | 49 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 17 | 17 |
| Q4 2024 | 30 | 18 |
| Q1 2025 | 15 | 27 |
| Q2 2025 | 23 | 15 |
| Q3 2025 | 33 | 17 |
| Q4 2025 | 31 | 31 |
| Q1 2026 | 28 | 23 |
| Q2 2026 | 25 | 30 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $2.7m | $574.5k | 0.21 |
| Q4 2025 | $776.0k | $643.8k | 0.83 |
| Q1 2026 | $321.4k | $25.5k | 0.08 |
| Q2 2026 | $333.1k | $32.4k | 0.10 |
Biggest buyers
| Commodore Capital LP | New | +2.8m |
| RENAISSANCE TECHNOLOGIES LLC | Added | +439.2k |
| TWO SIGMA INVESTMENTS, LP | Added | +378.4k |
| GROUP ONE TRADING LLC | Added | +284.5k |
| ACADIAN ASSET MANAGEMENT LLC | Added | +204.9k |
| AdvisorShares Investments LLC | Added | +161.5k |
| Verdad Advisers, LP | Added | +108.4k |
| CITADEL ADVISORS LLC | New | +68.8k |
| Virtu Financial LLC | New | +66.0k |
| OSAIC HOLDINGS, INC. | Added | +39.8k |
Biggest sellers
| ORBIMED ADVISORS LLC | Sold out | -3.1m |
| TCG Crossover Management, LLC | Sold out | -2.7m |
| STEMPOINT CAPITAL LP | Reduced | -616.7k |
| MILLENNIUM MANAGEMENT LLC | Sold out | -430.4k |
| ADAR1 Capital Management, LLC | Reduced | -400.0k |
| Shay Capital LLC | Sold out | -144.5k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Sold out | -142.6k |
| JANE STREET GROUP, LLC | Reduced | -108.0k |
| TUDOR INVESTMENT CORP ET AL | Sold out | -106.2k |
| DIADEMA PARTNERS LP | Sold out | -105.4k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $95.5k415.4k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $69.3k306.6k shares |
| SIMPLEX TRADING, LLC | Added | $42.1k186.4k shares |
| TUDOR INVESTMENT CORP ET AL | New | $37.7k167.0k shares |
| CITADEL ADVISORS LLC | Reduced | $33.7k149.0k shares |
| GROUP ONE TRADING LLC | Added | $24.0k106.2k shares |
| JANE STREET GROUP, LLC | Added | $17.3k76.5k shares |
| DIADEMA PARTNERS LP | New | $13.0k57.7k shares |
| Persistent Asset Partners Ltd | New | $394147 shares |
Biggest puts
| SIMPLEX TRADING, LLC | Added | $12.7k56.4k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $10.2k44.3k shares |
| JANE STREET GROUP, LLC | New | $5.5k24.5k shares |
| CITADEL ADVISORS LLC | Reduced | $3.4k15.1k shares |
| GROUP ONE TRADING LLC | New | $5202.3k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| TCG Crossover GP II, LLC 13G · passive investor filed 2026-05-15 | 10.0% |
| BIOTECHNOLOGY VALUE FUND L P 13G · passive investor filed 2025-02-14 | 10.0% |
| Commodore Capital LP 13G · passive investor no change · filed 2026-08-14 | 9.9% |
| TCG Crossover GP I, LLC 13G · passive investor filed 2026-08-14 | 6.7% |
Fell to 5% or below in the last year: ORBIMED ADVISORS LLC (0.0%, 2026-08-14), JANUS HENDERSON GROUP PLC (0.0%, 2026-02-17), GREAT POINT PARTNERS LLC (5.0%, 2026-02-17), STEMPOINT CAPITAL LP (1.5%, 2026-02-17), Nantahala Capital Management, LLC (4.7%, 2026-02-13), VANGUARD GROUP INC (4.6%, 2026-01-30)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported since 1 Apr 2026.
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Commodore Capital LP 0.04% of their portfolio | 2.8m $630.2k | New |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.6m $355.8k | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 848.0k $191.6k | Added +378.4k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 794.6k $178.0k | Added +204.9k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 730.5k $165.1k | Added +439.2k |
| STEMPOINT CAPITAL LP 0.00% of their portfolio | 616.7k $17.3k | Reduced -616.7k |
| Ikarian Capital, LLC 0.02% of their portfolio | 519.1k $117.3k | Unchanged |
| AdvisorShares Investments LLC 0.01% of their portfolio | 438.6k $99.1k | Added +161.5k |
| LUMINUS MANAGEMENT LLC 0.06% of their portfolio | 403.1k $91.1k | Added +7.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 365.0k $82.5k | Reduced -88.4k |
| ADAR1 Capital Management, LLC 0.00% of their portfolio | 351.1k $79.4k | Reduced -400.0k |
| BlackRock, Inc. 0.00% of their portfolio | 345.4k $78.1k | Reduced -103.1k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 304.4k $68.8k | Added +284.5k |
| Verdad Advisers, LP 0.06% of their portfolio | 293.3k $66.3k | Added +108.4k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 217.7k $49.2k | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 164.8k $37.3k | Reduced -108.0k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.00% of their portfolio | 134.6k $30.4k | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 121.1k $27.4k | Unchanged |
| XTX Topco Ltd 0.00% of their portfolio | 118.4k $26.8k | Reduced -34.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 80.8k $18.3k | Added +8.2k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 68.8k $15.6k | New |
| Virtu Financial LLC 0.00% of their portfolio | 66.0k $15.0k | New |
| UBS Group AG 0.00% of their portfolio | 57.8k $13.1k | Reduced -20.9k |
| GSA CAPITAL PARTNERS LLP 0.00% of their portfolio | 54.6k $12.0k | Added +4.7k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 43.9k $10.1k | Added +39.8k |
| Confluence Wealth Services, Inc. 0.00% of their portfolio | 32.6k $7.4k | New |
| Scientech Research LLC 0.01% of their portfolio | 30.3k $6.8k | New |
| R Squared Ltd 0.00% of their portfolio | 27.7k $6.3k | New |
| Kestra Advisory Services, LLC 0.00% of their portfolio | 26.0k $5.9k | Unchanged |
| HighTower Advisors, LLC 0.00% of their portfolio | 20.6k $4.7k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 18.1k $4.1k | Added +16.6k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 16.6k $3.7k | New |
| Truvestments Capital LLC 0.00% of their portfolio | 15.5k $3.5k | Reduced -1.5k |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 15.0k $3.4k | New |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 14.9k $3.4k | Reduced -33 |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 14.3k $3.2k | Reduced -75.4k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 12.0k $2.8k | New |
| StoneX Group Inc. 0.00% of their portfolio | 10.8k $6.6k | Reduced -4.4k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 10.8k $2.4k | Unchanged |
| Performa Ltd (US), LLC 0.00% of their portfolio | 5.5k $1.2k | Reduced -2.0k |
| CITIGROUP INC 0.00% of their portfolio | 3.8k $864 | Added +3.8k |
| Integrated Wealth Concepts LLC 0.00% of their portfolio | 556 $126 | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 500 $0 | Reduced -1.6k |
| MORGAN STANLEY 0.00% of their portfolio | 298 $67 | Added +297 |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 289 $65 | Added +1 |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 114 $80 | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 82 $62 | Added +66 |
| Fairman Group, LLC 0.00% of their portfolio | 29 $7 | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 6 $1 | Reduced -7 |