BRAIDWELL LP

STAMFORD, CT · CIK 1920938 · 13F filing filed 2026-08-14

SEC-registered investment adviser since 2022 · limited partnership

Assets managed$3.6bn
Staff32 · 19 in investment roles
Main clients (by assets)Private funds 100%
Private funds12 (11 hedge) · $3.6bn gross assets
Websitebraidwell.com
Form ADV · 2026-09-22SEC adviser record

$2.7bn reported value -9.8% vs Q1 2026

86positions

31.6%in top 10

24 new 21 added 36 reduced 26 sold out vs Q1 2026

Holdings, Q2 2026

The small lines show how much was held over the last 4 quarters (adjusted for stock splits).

#	Security	Ticker	Shares	Value	% of portfolio	Change	Shares change
1	CARIS LIFE SCIENCES INC COM CAI	CAI	8,256,032	$147.1m5.44%	5.44%	Added +246.6k	+246,585 3.1%
2	HINGE HEALTH INC CL A HNGE	HNGE	1,330,127	$110.4m4.08%	4.08%	Reduced -125.0k	-124,996 -8.6%
3	GLAUKOS CORP COM GKOS	GKOS	591,927	$82.7m3.06%	3.06%	Reduced -171.6k	-171,578 -22.5%
4	EDGEWISE THERAPEUTICS INC COM EWTX	EWTX	1,996,965	$81.1m3.00%	3.00%	Reduced -350.6k	-350,618 -14.9%
5	SPYRE THERAPEUTICS INC COM NEW SYRE	SYRE	879,467	$78.1m2.89%	2.89%	Reduced -53.4k	-53,356 -5.7%
6	IRHYTHM TECHNOLOGIES INC COM IRTC	IRTC	654,262	$77.8m2.88%	2.88%	Added +44.1k	+44,070 7.2%
7	NEOGENOMICS INC COM NEW NEO	NEO	4,918,202	$71.8m2.65%	2.65%	Reduced -699.2k	-699,200 -12.4%
8	KODIAK SCIENCES INC COM KOD	KOD	1,787,318	$69.6m2.58%	2.58%	Reduced -31.3k	-31,347 -1.7%
9	XENON PHARMACEUTICALS INC COM XENE	XENE	1,131,452	$68.3m2.53%	2.53%	Reduced -207.0k	-207,000 -15.5%
10	ALPHATEC HLDGS INC NOTE 0.750% 3/1 · principal ATEC 0.75 03.15.30 · principal	ATEC 0.75 03.15.30	69,121,000	$66.2m2.45%	2.45%	Added +7.5m	+7,500,000 12.2%
11	MONTE ROSA THERAPEUTICS INC COM GLUE	GLUE	2,451,562	$59.3m2.19%	2.19%	Reduced -755.0k	-755,012 -23.6%
12	DIANTHUS THERAPEUTICS INC COM DNTH	DNTH	594,562	$58.0m2.14%	2.14%	Reduced -304.8k	-304,802 -33.9%
13	NEUROCRINE BIOSCIENCES INC COM NBIX	NBIX	336,171	$56.7m2.10%	2.10%	Reduced -315.9k	-315,950 -48.5%
14	ALPHATEC HLDGS INC COM NEW ATEC	ATEC	6,531,439	$56.5m2.09%	2.09%	Added +4.4m	+4,358,714 200.6%
15	GENERATE BIOMEDICINES INC COM SHS GENB	GENB	3,283,844	$55.4m2.05%	2.05%	Reduced -309.2k	-309,155 -8.6%
16	MARAVAI LIFESCIENCES HLDGS I COM CL A MRVI	MRVI	8,702,921	$54.3m2.01%	2.01%	Reduced -1.5m	-1,537,243 -15.0%
17	KRYSTAL BIOTECH INC COM KRYS	KRYS	128,975	$47.9m1.77%	1.77%	Reduced -53.5k	-53,450 -29.3%
18	HUMANA INC COM HUM	HUM	114,500	$45.5m1.68%	1.68%	New
19	THERMO FISHER SCIENTIFIC INC COM TMO	TMO	89,395	$44.8m1.66%	1.66%	Reduced -3.5k	-3,520 -3.8%
20	KYMERA THERAPEUTICS INC COM KYMR	KYMR	378,163	$43.4m1.60%	1.60%	Added +40.6k	+40,604 12.0%
21	RHYTHM PHARMACEUTICALS INC COM RYTM	RYTM	381,128	$42.3m1.57%	1.57%	Added +70.5k	+70,500 22.7%
22	DAMORA THERAPEUTICS INC COM NEW COM NEW		1,620,377	$42.1m1.56%	1.56%	Added +725.5k	+725,531 81.1%
23	ACADIA PHARMACEUTICALS INC COM ACAD	ACAD	1,646,399	$41.7m1.54%	1.54%	Reduced -824.8k	-824,800 -33.4%
24	BRIGHTSPRING HEALTH SVCS INC COM BTSG	BTSG	596,753	$41.6m1.54%	1.54%	Reduced -419.8k	-419,809 -41.3%
25	TRANSMEDICS GROUP INC COM TMDX	TMDX	609,715	$40.5m1.50%	1.50%	Added +280.3k	+280,324 85.1%
26	MBX BIOSCIENCES INC COM MBX	MBX	710,880	$39.2m1.45%	1.45%	Reduced -781.6k	-781,587 -52.4%
27	CLIMB BIO INC COM CLYM	CLYM	2,797,375	$36.5m1.35%	1.35%	Added +1.3m	+1,267,700 82.9%
28	CAREDX INC COM CDNA	CDNA	1,220,602	$34.8m1.29%	1.29%	Reduced -952.5k	-952,544 -43.8%
29	MAZE THERAPEUTICS INC COM MAZE	MAZE	1,140,040	$34.0m1.26%	1.26%	New
30	BRIGHT MINDS BIOSCIENCES INC COM NEW DRUG	DRUG	483,822	$34.0m1.26%	1.26%	Reduced -55.9k	-55,886 -10.3%
31	ACADIA HEALTHCARE COMPANY IN COM ACHC	ACHC	1,141,477	$33.7m1.25%	1.25%	Added +495.6k	+495,577 76.7%
32	NEKTAR THERAPEUTICS COM NEW NKTR	NKTR	473,617	$33.1m1.22%	1.22%	Added +250.9k	+250,916 112.7%
33	CORVUS PHARMACEUTICALS INC COM CRVS	CRVS	2,126,298	$31.8m1.18%	1.18%	Added +373.5k	+373,500 21.3%
34	NURIX THERAPEUTICS INC COM NRIX	NRIX	1,286,769	$31.2m1.15%	1.15%	Reduced -464.0k	-463,997 -26.5%
35	INSPIRE MED SYS INC COM INSP	INSP	677,570	$30.2m1.12%	1.12%	Unchanged
36	AVALO THERAPEUTICS INC COM NEW AVTX	AVTX	1,629,182	$30.1m1.11%	1.11%	New
37	ALAMAR BIOSCIENCES INC COMMON STOCK ALMR	ALMR	1,083,983	$29.4m1.09%	1.09%	New
38	DANAHER CORPORATION COM DHR	DHR	150,627	$28.7m1.06%	1.06%	Added +11.3k	+11,300 8.1%
39	INTUITIVE SURGICAL INC COM NEW ISRG	ISRG	70,137	$27.9m1.03%	1.03%	Reduced -7.2k	-7,160 -9.3%
40	ORUKA THERAPEUTICS INC COM ORKA	ORKA	278,164	$26.5m0.98%	0.98%	New
41	AVALYN PHARMACEUTICALS INC COM SHS AVLN	AVLN	801,395	$26.4m0.98%	0.98%	New
42	AVEANNA HEALTHCARE HLDGS INC COM AVAH	AVAH	3,065,106	$26.3m0.97%	0.97%	Added +861.6k	+861,600 39.1%
43	BIOAGE LABS INC COM BIOA	BIOA	1,033,129	$25.3m0.94%	0.94%	Reduced -167.5k	-167,458 -13.9%
44	BOSTON SCIENTIFIC CORP COM BSX	BSX	587,567	$25.1m0.93%	0.93%	Added +241.1k	+241,100 69.6%
45	VERA THERAPEUTICS INC CL A VERA	VERA	564,724	$24.2m0.90%	0.90%	Added +40.9k	+40,900 7.8%
46	REPLIGEN CORP COM RGEN	RGEN	177,100	$24.2m0.89%	0.89%	Added +129.6k	+129,600 272.8%
47	ZURA BIO LTD CLASS A ORD SHS ZURA	ZURA	3,980,295	$23.5m0.87%	0.87%	Reduced -8.7k	-8,694 -0.2%
48	GUARDANT HEALTH INC COM GH	GH	147,850	$22.2m0.82%	0.82%	Reduced -351.9k	-351,862 -70.4%
49	EVOLUS INC COM EOLS	EOLS	3,155,209	$21.9m0.81%	0.81%	Added +50.0k	+50,000 1.6%
50	NATERA INC COM NTRA	NTRA	79,500	$21.6m0.80%	0.80%	Reduced -49.5k	-49,500 -38.4%
51	ORTHOPEDIATRICS CORP COM KIDS	KIDS	1,100,370	$21.1m0.78%	0.78%	Unchanged
52	ELEVANCE HEALTH INC COM ELV	ELV	53,960	$20.9m0.77%	0.77%	Reduced -8.1k	-8,120 -13.1%
53	TECTONIC THERAPEUTIC INC COM TECX	TECX	596,900	$20.5m0.76%	0.76%	Reduced -250.3k	-250,251 -29.5%
54	DYNE THERAPEUTICS INC COM DYN	DYN	921,598	$20.5m0.76%	0.76%	Reduced -760.4k	-760,400 -45.2%
55	NEOGENOMICS INC NOTE 0.250% 1/1 · principal NEO 0.25 01.15.28 · principal	NEO 0.25 01.15.28	18,011,000	$16.9m0.62%	0.62%	Reduced -82.4m	-82,370,000 -82.1%
56	IMMUNOCORE HLDGS PLC ADS IMCR	IMCR	521,327	$16.6m0.61%	0.61%	New
57	REPLIGEN CORP NOTE 1.000%12/1 · principal RGEN 1 12.15.28 · principal	RGEN 1 12.15.28	16,000,000	$16.4m0.61%	0.61%	Reduced -85.0m	-85,000,000 -84.2%
58	ARGENX SE SPONSORED ADR ARGX	ARGX	17,707	$16.4m0.61%	0.61%	Reduced -67.2k	-67,232 -79.2%
59	CELLDEX THERAPEUTICS INC NEW COM NEW CLDX	CLDX	436,646	$16.2m0.60%	0.60%	Reduced -919.4k	-919,436 -67.8%
60	OVID THERAPEUTICS INC COM OVID	OVID	5,919,464	$15.9m0.59%	0.59%	New
61	MANNKIND CORP COM NEW MNKD	MNKD	3,458,429	$14.7m0.54%	0.54%	New
62	UNIQURE NV SHS QURE	QURE	301,652	$13.9m0.51%	0.51%	New
63	X4 PHARMACEUTICALS INC COM NEW XFOR	XFOR	2,922,754	$13.6m0.50%	0.50%	Reduced -350.2k	-350,200 -10.7%
64	ORIC PHARMACEUTICALS INC COM ORIC	ORIC	1,214,540	$13.2m0.49%	0.49%	Added +86.5k	+86,500 7.7%
65	KINIKSA PHARMACEUTICALS INTL ORD SHS CL A KNSA	KNSA	183,822	$11.8m0.43%	0.43%	Reduced -88.7k	-88,700 -32.5%
66	OCULIS HOLDING AG ORDINARY SHARES OCS	OCS	834,183	$11.6m0.43%	0.43%	New
67	ACLARIS THERAPEUTICS INC COM ACRS	ACRS	2,142,348	$11.3m0.42%	0.42%	Added +443.2k	+443,232 26.1%
68	SEAPORT THERAPEUTICS INC COMMON STOCK SPTX	SPTX	500,000	$10.9m0.40%	0.40%	New
69	VOR BIOPHARMA INC COM NEW VOR	VOR	573,104	$10.6m0.39%	0.39%	Added +106.3k	+106,330 22.8%
70	SURROZEN INC COM NEW SRZN	SRZN	390,753	$10.1m0.38%	0.38%	Reduced -5.3k	-5,347 -1.4%
71	IMMUNIC INC COM NEW IMUX	IMUX	645,010	$9.9m0.37%	0.37%	New
72	HELIX ACQUISITION CORP III USD CL A ORD SHS HLXC	HLXC	900,000	$9.5m0.35%	0.35%	Unchanged
73	IONIS PHARMACEUTICALS INC COM IONS	IONS	116,762	$9.3m0.34%	0.34%	Reduced -14.1k	-14,100 -10.8%
74	QUEST DIAGNOSTICS INC COM DGX	DGX	43,200	$9.2m0.34%	0.34%	New
75	ADLAI NORTYE LTD SPONSORED ADS ANL	ANL	795,214	$9.1m0.34%	0.34%	New
76	TENAX THERAPEUTICS INC COM NEW TENX	TENX	584,412	$8.5m0.31%	0.31%	New
77	KARDIGAN INC COM KARD	KARD	300,000	$7.2m0.26%	0.26%	New
78	AMANAT ACQUISITION CORP CL A ORD AMAN	AMAN	700,000	$7.1m0.26%	0.26%	New
79	HEMAB THERAPEUTICS HLDGS INC COM SHS COAG	COAG	160,000	$5.9m0.22%	0.22%	New
80	GH RESEARCH PLC ORDINARY SHARES GHRS	GHRS	207,240	$5.6m0.21%	0.21%	New
81	WATERS CORP COM WAT	WAT	14,040	$5.3m0.19%	0.19%	New
82	RESEARCH ALLIANCE CORP III ORD SHS CL A RACC	RACC	400,000	$4.3m0.16%	0.16%	New
83	JATT II ACQUISITION CORP ORD SHS JATT	JATT	250,000	$2.8m0.11%	0.11%	New
84	PULMONX CORP COM LUNG	LUNG	752,541	$978.3k0.04%	0.04%	Unchanged
85	VYNE THERAPEUTICS INC COM COM		916,077	$596.1k0.02%	0.02%	Unchanged
86	CYCLERION THERAPEUTICS INC COM COM		156,890	$531.9k0.02%	0.02%	New

Sold out since Q1 2026

Security	Ticker	Shares held before	Value then
GUARDANT HEALTH INC GH 1.25 02.15.31	GH 1.25 02.15.31	60,954,000	$102.6m61.0m shares
CENTESSA PHARMACEUTICALS PLC		1,986,768	$78.9m2.0m shares
NUVALENT INC		700,429	$71.8m700.4k shares
CG ONCOLOGY INC CGON	CGON	984,783	$66.7m984.8k shares
APOGEE THERAPEUTICS INC		478,667	$40.3m478.7k shares
PENUMBRA INC PEN	PEN	105,352	$34.6m105.4k shares
SOLENO THERAPEUTICS INC SLNO	SLNO	959,259	$32.1m959.3k shares
ILLUMINA INC ILMN	ILMN	229,215	$28.3m229.2k shares
BIOMARIN PHARMACEUTICAL INC BMRN	BMRN	497,020	$28.1m497.0k shares
ESTABLISHMENT LABS HLDGS INC ESTA	ESTA	463,600	$26.3m463.6k shares
FULCRUM THERAPEUTICS INC FULC	FULC	3,134,922	$24.0m3.1m shares
CVS HEALTH CORP CVS	CVS	290,700	$20.9m290.7k shares
TARSUS PHARMACEUTICALS INC TARS	TARS	265,715	$18.6m265.7k shares
ENGENE HOLDINGS INC		2,456,870	$16.7m2.5m shares
ZENAS BIOPHARMA INC ZBIO 2.5 04.01.32	ZBIO 2.5 04.01.32	13,000,000	$13.5m13.0m shares
TG THERAPEUTICS INC TGTX	TGTX	358,800	$11.9m358.8k shares
CENTENE CORP DEL CNC	CNC	330,000	$10.8m330.0k shares
COMPASS THERAPEUTICS INC CMPX	CMPX	1,965,106	$10.4m2.0m shares
REVOLUTION MEDICINES INC RVMD	RVMD	84,900	$8.3m84.9k shares
GRAIL INC GRAL	GRAL	142,755	$7.4m142.8k shares
DENALI THERAPEUTICS INC DNLI	DNLI	296,324	$5.7m296.3k shares
HARROW INC HROW	HROW	156,419	$5.5m156.4k shares
REVVITY INC RVTY	RVTY	48,400	$4.2m48.4k shares
CELCUITY INC CELC	CELC	29,198	$3.3m29.2k shares
PRAXIS PRECISION MEDICINES I PRAX	PRAX	9,976	$3.2m10.0k shares

Stakes above 5%

Companies where this manager has reported owning more than 5% of a class of shares, on Schedule 13D (may seek influence) or 13G (passive): its latest filing for each, from 19 Dec 2024 on.

Company	Ticker	Stake	Change	Schedule	Last filed
AMANAT ACQUISITION CORP AMAN · 13G · filed 2026-08-14	AMAN	9.3%≈ $7.1m	new	13G	2026-08-14