Vault-13

VYNE THERAPEUTICS INC

COM · CUSIP 92941V308

45 institutional holders +1 vs Q1 2026
15,463,61915.5m shares reported held*
$10.1mreported value*
6 new 7 added 9 reduced 4 sold out net bought ≈ $691.1k (+1.1m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $0.65.

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

0204060Q1 23: 22Q2 23: 20Q3 23: 21Q4 23: 33Q1 24: 31Q2 24: 31Q3 24: 33Q4 24: 35Q1 25: 38Q2 25: 45Q3 25: 33Q4 25: 43Q1 26: 44Q2 26: 4545Q1 23Q4 23Q3 24Q2 25Q2 26
Numbers
QuarterHolders
Q1 202322
Q2 202320
Q3 202321
Q4 202333
Q1 202431
Q2 202431
Q3 202433
Q4 202435
Q1 202538
Q2 202545
Q3 202533
Q4 202543
Q1 202644
Q2 202645

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
40040Q3 24: 7 bought or addedQ3 24: 12 cut or sold outQ4 24: 16 bought or addedQ4 24: 14 cut or sold outQ4 24Q1 25: 21 bought or addedQ1 25: 11 cut or sold outQ2 25: 23 bought or addedQ2 25: 18 cut or sold outQ2 25Q3 25: 15 bought or addedQ3 25: 24 cut or sold outQ4 25: 21 bought or addedQ4 25: 11 cut or sold outQ4 25Q1 26: 16 bought or addedQ1 26: 9 cut or sold outQ2 26: 13 bought or addedQ2 26: 13 cut or sold outQ2 26
Numbers
QuarterBought or addedCut or sold out
Q3 2024712
Q4 20241614
Q1 20252111
Q2 20252318
Q3 20251524
Q4 20252111
Q1 2026169
Q2 20261313

Biggest buyers

Nantahala Capital Management, LLC Added +2,000,000+2.0m
ADAR1 Capital Management, LLC Added +1,886,101+1.9m
GSA CAPITAL PARTNERS LLP New +71,533+71.5k
SUPERSTRING CAPITAL MANAGEMENT LP New +61,269+61.3k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added +61,173+61.2k
TWO SIGMA SECURITIES, LLC New +40,697+40.7k
NORTHERN TRUST CORP Added +20,567+20.6k
TWO SIGMA INVESTMENTS, LP Added +12,406+12.4k
Tower Research Capital LLC (TRC) Added +9,467+9.5k
RENAISSANCE TECHNOLOGIES LLC Added +6,000+6.0k

Biggest sellers

Anson Funds Management LP Reduced -2,471,757-2.5m
Shay Capital LLC Reduced -153,591-153.6k
UBS Group AG Reduced -121,187-121.2k
BOOTHBAY FUND MANAGEMENT, LLC Sold out -81,371-81.4k
XTX Topco Ltd Reduced -79,675-79.7k
GEODE CAPITAL MANAGEMENT, LLC Reduced -64,508-64.5k
JANE STREET GROUP, LLC Reduced -54,671-54.7k
CITADEL ADVISORS LLC Reduced -45,986-46.0k
HRT FINANCIAL LP Sold out -27,569-27.6k
Rangeley Capital, LLC Reduced -5,000-5.0k

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Nantahala Capital Management, LLC 13G · institution new · filed 2026-05-15 6.0% new 2.0m≈ $1.3m 2026-05-15

Fell to 5% or below in the last year: CITADEL ADVISORS LLC (0.0%, 2025-11-14), EVENTIDE ASSET MANAGEMENT, LLC (0.0%, 2025-11-14), Cormorant Asset Management, LP (0.0%, 2025-11-14)

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Nantahala Capital Management, LLC 0.08% of their portfolio NEW CANAAN, CT 4,000,0004.0m $2.6m $2.6m 0.08% Added +2.0m +2,000,000
2 ADAR1 Capital Management, LLC 0.09% of their portfolio AUSTIN, TX 2,950,0003.0m $1.9m $1.9m 0.09% Added +1.9m +1,886,101
3 Lynx1 Capital Management LP 0.12% of their portfolio DORADO, PR 1,628,7001.6m $1.1m $1.1m 0.12% Unchanged
4 Shay Capital LLC 0.10% of their portfolio NEW YORK, NY 1,456,6511.5m $947.8k $947.8k 0.10% Reduced -153.6k -153,591
5 T3 Companies, LLC 0.70% of their portfolio NEW YORK, NY 945,000945.0k $614.9k $614.9k 0.70% Unchanged
6 BRAIDWELL LP 0.02% of their portfolio STAMFORD, CT 916,077916.1k $596.1k $596.1k 0.02% Unchanged
7 KVP Capital Advisors, LP 0.24% of their portfolio SAN FRANCISCO, CA 500,551500.6k $325.7k $325.7k 0.24% Unchanged
8 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 468,457468.5k $304.8k $304.8k 0.00% Reduced -46.0k -45,986
9 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 438,818438.8k $285.5k $285.5k 0.00% Added +12.4k +12,406
10 ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio Boston, MA 381,797381.8k $248.0k $248.0k 0.00% Unchanged
11 Ikarian Capital, LLC 0.03% of their portfolio DALLAS, TX 264,912264.9k $172.4k $172.4k 0.03% Unchanged
12 VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio MALVERN, PA 264,557264.6k $172.2k $172.2k 0.00% Unchanged
13 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 258,203258.2k $168.0k $168.0k 0.00% Reduced -64.5k -64,508
14 VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio MALVERN, PA 183,443183.4k $119.4k $119.4k 0.00% Unchanged
15 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 118,957119.0k $77.4k $77.4k 0.00% Added +61.2k +61,173
16 Rangeley Capital, LLC 0.07% of their portfolio NEW CANAAN, CT 113,064113.1k $73.6k $73.6k 0.07% Reduced -5.0k -5,000
17 XTX Topco Ltd 0.00% of their portfolio LONDON, X0 78,72178.7k $51.2k $51.2k 0.00% Reduced -79.7k -79,675
18 GSA CAPITAL PARTNERS LLP 0.00% of their portfolio LONDON, X0 71,53371.5k $47.0k $47.0k 0.00% New
19 SUPERSTRING CAPITAL MANAGEMENT LP 0.03% of their portfolio NEW YORK, NY 61,26961.3k $39.9k $39.9k 0.03% New
20 UBS Group AG 0.00% of their portfolio ZURICH, V8 58,59758.6k $38.1k $38.1k 0.00% Reduced -121.2k -121,187
21 BlackRock, Inc. 0.00% of their portfolio New York, NY 44,40544.4k $28.9k $28.9k 0.00% Unchanged
22 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 43,67743.7k $28.4k $28.4k 0.00% Added +20.6k +20,567
23 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 40,97441.0k $26.7k $26.7k 0.00% Reduced -54.7k -54,671
24 TWO SIGMA SECURITIES, LLC 0.00% of their portfolio NEW YORK, NY 40,69740.7k $26.5k $26.5k 0.00% New
25 FNY Investment Advisers, LLC 0.01% of their portfolio NEW YORK, NY 35,00035.0k $22.0k $22.0k 0.01% Unchanged
26 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 23,30023.3k $15.2k $15.2k 0.00% Added +6.0k +6,000
27 COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio WALTHAM, MA 18,29818.3k $11.9k $11.9k 0.00% Unchanged
28 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 15,76515.8k $10.3k $10.3k 0.00% Unchanged
29 Anson Funds Management LP 0.00% of their portfolio DALLAS, TX 14,45514.5k $9.4k $9.4k 0.00% Reduced -2.5m -2,471,757
30 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 12,99413.0k $8.5k $8.5k 0.00% Added +9.5k +9,467
31 Harvest Investment Services, LLC 0.00% of their portfolio Oakbrook Terrace, IL 11,05911.1k $7.2k $7.2k 0.00% Unchanged
32 ACORN CAPITAL ADVISORS, LLC 0.00% of their portfolio NEW YORK, NY 1,4251.4k $926 $926 0.00% Unchanged
33 MB, LEVIS & ASSOCIATES, LLC 0.00% of their portfolio CENTER VALLEY, PA 1,0411.0k $677 $677 0.00% Unchanged
34 Hurley Capital, LLC 0.00% of their portfolio NEW YORK, NY 561561 $365 $365 0.00% Unchanged
35 Centerpoint Advisors, LLC 0.00% of their portfolio NEEDHAM, MA 350350 $0 $0 0.00% Unchanged
36 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 141141 $92 $92 0.00% New
37 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 6565 $42 $42 0.00% Unchanged
38 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 4343 $28 $28 0.00% Unchanged
39 Truvestments Capital LLC 0.00% of their portfolio SARASOTA, FL 2525 $16 $16 0.00% Unchanged
40 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 1515 $0 $0 0.00% Unchanged
41 NFSG Corp 0.00% of their portfolio BOCA RATON, FL 1010 $7 $7 0.00% Unchanged
42 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 88 $5 $5 0.00% Reduced -138 -138
43 Larson Financial Group LLC 0.00% of their portfolio ST LOUIS, MO 22 $1 $1 0.00% Unchanged
44 Steward Partners Investment Advisory, LLC 0.00% of their portfolio STAMFORD, CT 11 $1 $1 0.00% New
45 FLAGSHIP WEALTH ADVISORS, LLC 0.00% of their portfolio WAKEFIELD, MA 11 $1 $1 0.00% New