KARDIGAN INC KARD
COM · Common Stock · CUSIP 485925101
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 93.5m as of 2026-08-07, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $23.91.
Biggest buyers
| HRTG GPE, LLC | New | +16.9m |
| FMR LLC | New | +8.9m |
| PERCEPTIVE ADVISORS LLC | New | +8.2m |
| T. Rowe Price Investment Management, Inc. | New | +4.2m |
| Capital Research Global Investors | New | +3.6m |
| JPMORGAN CHASE & CO | New | +1.8m |
| ALLIANCEBERNSTEIN L.P. | New | +1.5m |
| Liberty Mutual Group Asset Management Inc. | New | +1.2m |
| JENNISON ASSOCIATES LLC | New | +903.6k |
| Paradigm Biocapital Advisors LP | New | +900.0k |
Biggest sellers
| None |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| HRTG GPE, LLC 13G · passive investor new · filed 2026-06-29 | 18.2% |
ARCH Venture Fund XIII, L.P.
13D · may seek influence
new · filed 2026-06-29
Stated purposeAVF XIII and the other Reporting Persons acquired the Common Stock for investment purposes. Depending on market conditions, the continuing evaluation of the business and prospects of the Issuer and other factors, AVF XIII and other Reporting Persons may dispose of or acquire additional shares of Common Stock of the Issuer. Except as set forth above, none of the Reporting Persons has any present plans which relate to or would result in the matters set forth in subparagraphs (a) - (j) of Item 4 of Schedule 13D. Full filing |
16.2% |
| GIANAKAKOS ANASTASIOS 13G · exempt (held before listing) new · filed 2026-08-13 | 11.1% |
| FMR LLC 13G · institution +0.3 pts · filed 2026-08-07 | 10.3% |
PERCEPTIVE ADVISORS LLC
13D · may seek influence
-0.1 pts · filed 2026-10-01
Stated purposeItem 4 of the Schedule 13D is amended and supplemented as followed: On September 29, 2026, Douglas Giordano, a Managing Director at Perceptive Advisors, resigned from the board of directors of the Issuer. The Reporting Persons continuously review their investment in the Issuer and, subject to applicable securities laws, regulatory requirements, and the lock-up agreement disclosed in the previously filed Schedule 13D, may from time to time acquire additional shares of Common Stock or other securities of the Issuer, hedge some or all of their economic exposure through short sales, options, swaps or other derivative or hedging transactions, or dispose of or distribute some or a significant amount of their Common Stock or other securities of the Issuer held or subsequently acquired, dependin… Full filing |
8.8% |
| Edelberg Jay 13G · exempt (held before listing) new · filed 2026-08-13 | 5.2% |
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 2 | $20.0m | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-06-22 | HRTG GPE, LLC +4 10% owner · HRTG PV, L.P. | Bought | $50.0m3.1m shares |
| 2026-06-22 | CRANDELL KEITH +6 Director · By: ARCH Venture Fund XIII, L.P. | Bought | $20.0m1.2m shares |
| 2026-06-22 | BERNS PAUL L Director · By ARCH Venture Fund XIII, L.P. | Bought | $20.0m1.2m shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| HRTG GPE, LLC 16.26% of their portfolio | 16.9m $403.5m | New |
| FMR LLC 0.01% of their portfolio | 8.9m $212.5m | New |
| PERCEPTIVE ADVISORS LLC 3.04% of their portfolio | 8.2m $195.6m | New |
| T. Rowe Price Investment Management, Inc. 0.07% of their portfolio | 4.2m $100.3m | New |
| Capital Research Global Investors 0.01% of their portfolio | 3.6m $85.8m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.8m $46.4m | New |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 1.5m $36.6m | New |
| Liberty Mutual Group Asset Management Inc. 2.49% of their portfolio | 1.2m $28.5m | New |
| JENNISON ASSOCIATES LLC 0.01% of their portfolio | 903.6k $21.6m | New |
| Paradigm Biocapital Advisors LP 0.40% of their portfolio | 900.0k $21.5m | New |
| Jupiter Topco LLC 0.01% of their portfolio | 749.7k $17.7m | First filing |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 658.8k $15.7m | New |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 650.0k $15.5m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 645.0k $15.4m | New |
| Deep Track Capital, LP 0.21% of their portfolio | 600.0k $14.3m | New |
| Woodline Partners LP 0.03% of their portfolio | 414.0k $9.9m | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 400.0k $9.5m | New |
| MONTANOVA CAPITAL, LLC 0.20% of their portfolio | 400.0k $9.5m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 377.8k $9.0m | New |
| Catalio Capital Management, LP 1.40% of their portfolio | 312.5k $7.5m | New |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 300.0k $7.2m | New |
| EVENTIDE ASSET MANAGEMENT, LLC 0.10% of their portfolio | 300.0k $7.2m | New |
| BRAIDWELL LP 0.26% of their portfolio | 300.0k $7.2m | New |
| UBS Group AG 0.00% of their portfolio | 267.8k $6.4m | New |
| PEREGRINE CAPITAL MANAGEMENT LLC 0.18% of their portfolio | 229.8k $5.5m | New |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 223.1k $5.3m | New |
| Integral Health Asset Management, LLC 0.20% of their portfolio | 200.0k $4.8m | New |
| SEVEN GRAND MANAGERS, LLC 0.19% of their portfolio | 200.0k $4.8m | New |
| Driehaus Capital Management LLC 0.03% of their portfolio | 199.6k $4.8m | New |
| HRT FINANCIAL LP 0.01% of their portfolio | 156.2k $3.7m | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 149.5k $3.6m | New |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 130.8k $3.1m | New |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 120.0k $2.9m | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 109.8k $2.6m | New |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 102.5k $2.4m | New |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.00% of their portfolio | 74.2k $1.8m | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 66.8k $1.6m | New |
| MORGAN STANLEY 0.00% of their portfolio | 65.4k $1.6m | New |
| TD Asset Management Inc 0.00% of their portfolio | 55.8k $1.3m | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 53.8k $1.3m | New |
| Casdin Capital, LLC 0.06% of their portfolio | 50.0k $1.2m | New |
| Ghisallo Capital Management LLC 0.02% of their portfolio | 50.0k $1.2m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 44.5k $1.1m | New |
| Monashee Investment Management LLC 1.71% of their portfolio | 42.7k $1.0m | New |
| SEI INVESTMENTS CO 0.00% of their portfolio | 40.1k $957.0k | New |
| Shay Capital LLC 0.10% of their portfolio | 38.5k $918.2k | New |
| Alyeska Investment Group, L.P. 0.00% of their portfolio | 30.0k $715.5k | New |
| Burkehill Global Management, LP 0.03% of their portfolio | 30.0k $715.5k | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 19.8k $472.3k | New |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 19.0k $452.2k | New |
| OXFORD ASSET MANAGEMENT LLP 0.22% of their portfolio | 18.4k $438.3k | Not comparable |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 18.2k $435.2k | New |
| Virtu Financial LLC 0.01% of their portfolio | 15.1k $360.0k | New |
| Scientech Research LLC 0.29% of their portfolio | 15.0k $358.5k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 15.0k $357.8k | New |
| SOROS FUND MANAGEMENT LLC 0.00% of their portfolio | 15.0k $357.8k | New |
| XTX Topco Ltd 0.00% of their portfolio | 13.5k $321.7k | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 12.5k $298.1k | New |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 12.4k $295.4k | New |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 11.4k $270.8k | New |
| Mariner, LLC 0.00% of their portfolio | 10.9k $259.5k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 10.4k $247.3k | New |
| Legal & General Group Plc 0.00% of their portfolio | 5.0k $118.7k | New |
| DAFNA Capital Management LLC 0.02% of their portfolio | 5.0k $119.2k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 1.1k $26.8k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 350 $8.3k | New |
| FNY Investment Advisers, LLC 0.00% of their portfolio | 100 $2.0k | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 24 $572 | New |
| Strategic Wealth Partners, Ltd. 0.00% of their portfolio | 5 $119 | New |