VOR BIOPHARMA INC VOR
COM NEW · Common Stock · CUSIP 929033207
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersBoston, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($44.6k this quarter). Holder counts are more reliable. Shares outstanding: 59.2m as of 2026-08-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $18.41. Options: 1 managers hold calls ($11.0k notional), 1 hold puts ($1.2m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q1 2025 | 1 |
| Q2 2025 | 1 |
| Q3 2025 | 36 |
| Q4 2025 | 55 |
| Q1 2026 | 80 |
| Q2 2026 | 102 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2025 | 0 | 0 |
| Q3 2025 | 36 | 1 |
| Q4 2025 | 47 | 12 |
| Q1 2026 | 58 | 18 |
| Q2 2026 | 73 | 36 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $360.9m | $57.8m | 0.16 |
| Q4 2025 | $16.2m | $5.9m | 0.37 |
| Q1 2026 | $918.8k | $3.4m | 3.71 |
| Q2 2026 | $11.0k | $1.2m | 107.67 |
Biggest buyers
| FMR LLC | Added | +3.4m |
| BlackRock, Inc. | Added | +2.7m |
| Nantahala Capital Management, LLC | New | +1.7m |
| STATE STREET CORP | Added | +1.5m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +719.9k |
| ADAR1 Capital Management, LLC | New | +680.6k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +651.0k |
| NAN FUNG TRINITY (HK) LTD | New | +646.5k |
| Woodline Partners LP | New | +379.7k |
| VANGUARD PORTFOLIO MANAGEMENT LLC | New | +340.4k |
Biggest sellers
| RA CAPITAL MANAGEMENT, L.P. | Reduced | -3.0m |
| MARSHALL WACE, LLP | Reduced | -1.1m |
| Laurion Capital Management LP | Sold out | -318.7k |
| Propel Bio Management, LLC | Sold out | -314.5k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -216.2k |
| TUDOR INVESTMENT CORP ET AL | Reduced | -133.0k |
| NEXTBio Capital Management LP | Reduced | -110.8k |
| Jump Financial, LLC | Reduced | -102.1k |
| Logos Global Management LP | Reduced | -100.0k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -95.8k |
Biggest calls
| GROUP ONE TRADING LLC | Reduced | $11.0k600 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.2m64.6k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
RA CAPITAL MANAGEMENT, L.P.
13D · may seek influence
no change · filed 2026-07-21
Stated purposeItem 4 of the Statement is hereby amended and supplemented as follows: Effective July 6, 2026, Andrew Levin resigned from the Board of Directors of the Issuer. Full filing |
19.9% |
Reprogrammed Interchange LLC
13D · may seek influence
filed 2025-10-17
Stated purposeItem 4 of Schedule 13D is hereby amended and supplemented as follows: From October 15, 2025 through October 16, 2025, Reprogrammed Interchange LLC sold the following shares of Vor Biopharma Inc. in open market transactions, resulting in a decrease in the number of shares of Common Stock beneficially owned by the Reporting Persons by more than one percent of the outstanding shares of Common Stock of the Issuer. 1. 71,655 shares on October 15, 2025, at a weighted average per share sale price of $31.9196. 2. 2,021 shares on October 16, 2025, at a weighted average per share sale price of $30.4548. Full filing |
17.6% |
| FMR LLC 13G · institution +2.9 pts · filed 2026-08-07 | 12.0% |
| TCG Crossover GP II, LLC 13G · passive investor new · filed 2026-04-01 | 10.5% |
ForGrowth III PA B.V.
13D · may seek influence
no change · filed 2025-12-23
Stated purposeThe Reporting Persons acquired their shares of Common Stock as an investment in the ordinary course of business. On December 18, 2025, Wouter Joustra, a General Partner at Forbion Capital, was appointed to the Issuer's board of directors. The Reporting Persons, either directly or indirectly through Mr. Joustra, may engage in discussions from time to time with the Issuer's board of directors, the Issuer's management or the Issuer's other stockholders. These discussions may be with respect to (i) acquiring or disposing of the shares or other securities of the Issuer; (ii) maintaining or changing the Issuer's business, operations, governance, management, strategy or capitalization; or (iii) implementing transactions that may relate to or may result in any matter set forth in paragraphs (a) t… Full filing |
10.0% |
| Venrock Healthcare Capital Partners III, L.P. 13G · passive investor no change · filed 2026-08-14 | 9.9% |
| Verve Capital Ltd 13G · passive investor -3.0 pts · filed 2026-08-13 | 6.3% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-30 | 5.7% |
Fell to 5% or below in the last year: Frazier Life Sciences Public Fund, L.P. (4.2%, 2026-08-14), Qiming Venture Partners VIII-HC, L.P. (2.0%, 2026-05-06), GREAT POINT PARTNERS LLC (3.3%, 2026-02-17), Paradigm Biocapital Advisors LP (4.5%, 2026-02-17)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 1 | $12.9k | $12.9k |
| Q1 2025 | 0 | — | 1 | $6.7k | $6.7k |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 1 | $33.7m | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 0 | — | 1 | $49.4m | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-07-16 | RA Capital Healthcare Fund LP +3 10% owner · See footnotes | Sold | $4.2k213 shares |
| 2026-04-22 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $2.6m165.2k shares |
| 2026-04-20 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $2.7m172.0k shares |
| 2026-04-17 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $7.5m458.4k shares |
| 2026-04-15 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $858.8k53.6k shares |
| 2026-04-14 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $2.5m153.7k shares |
| 2026-04-13 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $8.6m530.6k shares |
| 2026-04-10 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $13.0k828 shares |
| 2026-04-09 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $2.2m135.2k shares |
| 2026-04-08 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $8.0m484.1k shares |
| 2026-04-06 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $9.8m589.3k shares |
| 2026-04-02 | RA Capital Healthcare Fund LP +3 Director · See footnotes | Sold | $4.7m260.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| TCG Crossover Management, LLC 2.51% of their portfolio | 5.7m $104.4m | Unchanged |
| FMR LLC 0.00% of their portfolio | 4.9m $90.8m | Added +3.4m |
| FCPM III SERVICES B.V. 10.10% of their portfolio | 4.1m $75.8m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 3.5m $63.8m | Added +2.7m |
| Venrock Adviser, LLC 1.70% of their portfolio | 3.0m $56.0m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 2.6m $48.2m | Added +1.5m |
| Frazier Life Sciences Management, L.P. 1.02% of their portfolio | 2.5m $46.8m | Unchanged |
| RA CAPITAL MANAGEMENT, L.P. 0.38% of their portfolio | 2.4m $44.2m | Reduced -3.0m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.1m $38.4m | Added +651.0k |
| Caligan Partners LP 1.71% of their portfolio | 1.9m $35.4m | Unchanged |
| Paradigm Biocapital Advisors LP 0.60% of their portfolio | 1.8m $32.2m | Unchanged |
| GREAT POINT PARTNERS LLC 7.37% of their portfolio | 1.7m $31.3m | Reduced -50.0k |
| Nantahala Capital Management, LLC 0.94% of their portfolio | 1.7m $31.1m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.1m $19.6m | Added +719.9k |
| NEXTBio Capital Management LP 7.53% of their portfolio | 889.2k $16.4m | Reduced -110.8k |
| ADAR1 Capital Management, LLC 0.59% of their portfolio | 680.6k $12.5m | New |
| Logos Global Management LP 0.52% of their portfolio | 650.0k $12.0m | Reduced -100.0k |
| Rosalind Advisors, Inc. 4.49% of their portfolio | 648.6k $11.9m | Reduced -51.4k |
| NAN FUNG TRINITY (HK) LTD 1.18% of their portfolio | 646.5k $11.9m | New |
| BRAIDWELL LP 0.39% of their portfolio | 573.1k $10.6m | Added +106.3k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.19% of their portfolio | 558.7k $10.3m | Added +3.0k |
| UBS Group AG 0.00% of their portfolio | 493.3k $9.1m | Added +4.9k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 428.1k $7.9m | Added +169.5k |
| SPHERA FUNDS MANAGEMENT LTD. 1.10% of their portfolio | 416.4k $7.7m | Added +94.5k |
| Woodline Partners LP 0.02% of their portfolio | 379.7k $7.0m | New |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 340.4k $6.3m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 328.9k $6.1m | Added +67.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 328.7k $6.1m | Added +264.2k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 300.7k $5.5m | Added +115.2k |
| Clearline Capital LP 0.34% of their portfolio | 285.3k $5.3m | Reduced -40.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 177.7k $3.3m | Added +64.8k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 160.4k $3.0m | Added +11.6k |
| Eversept Partners, LP 0.15% of their portfolio | 149.7k $2.8m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 121.4k $2.2m | Added +99.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 97.7k $1.8m | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 95.6k $1.8m | Reduced -1.1m |
| Nuveen, LLC 0.00% of their portfolio | 94.8k $1.7m | New |
| AXIOM INVESTORS LLC /DE 0.01% of their portfolio | 92.1k $1.7m | Reduced -3.6k |
| XTX Topco Ltd 0.02% of their portfolio | 82.6k $1.5m | New |
| Jump Financial, LLC 0.01% of their portfolio | 70.9k $1.3m | Reduced -102.1k |
| Invesco Ltd. 0.00% of their portfolio | 68.3k $1.3m | Added +56.7k |
| CITIGROUP INC 0.00% of their portfolio | 63.1k $1.2m | Added +57.8k |
| MORGAN STANLEY 0.00% of their portfolio | 61.6k $1.1m | Reduced -55.2k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 57.5k $1.1m | New |
| ALPS ADVISORS INC 0.00% of their portfolio | 55.0k $1.0m | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 54.7k $1.0m | New |
| JOHNSON & JOHNSON 0.12% of their portfolio | 53.7k $989.2k | Unchanged |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 48.8k $898.7k | Reduced -1.7k |
| Walleye Capital LLC 0.00% of their portfolio | 46.6k $858.1k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 41.8k $770.0k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 40.4k $742.9k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 37.2k $685.0k | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 37.0k $681.4k | New |
| Engineers Gate Manager LP 0.01% of their portfolio | 37.0k $680.3k | Added +10.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 36.3k $667.8k | Added +36.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 33.0k $607.7k | Reduced -95.8k |
| Jefferies Financial Group Inc. 0.01% of their portfolio | 32.7k $601.3k | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 27.1k $498.9k | New |
| Sarissa Capital Management LP 0.26% of their portfolio | 25.4k $467.6k | Unchanged |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 24.6k $452.7k | Added +2.6k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 24.4k $450.0k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 24.4k $449.9k | Added +20.9k |
| Squarepoint Ops LLC 0.00% of their portfolio | 23.2k $427.7k | Reduced -2.3k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 23.0k $423.9k | Added +9.3k |
| Virtus Investment Advisers, LLC 0.10% of their portfolio | 22.8k $419.5k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 21.6k $402.1k | Added +17.3k |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 19.6k $361.2k | Reduced -133.0k |
| Scientech Research LLC 0.28% of their portfolio | 18.8k $346.6k | Added +3.8k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 17.9k $330.4k | Added +5.1k |
| Y-Intercept (Hong Kong) Ltd 0.01% of their portfolio | 17.2k $317.4k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 16.5k $302.9k | Reduced -216.2k |
| FOX RUN MANAGEMENT, L.L.C. 0.05% of their portfolio | 15.3k $281.7k | New |
| BARCLAYS PLC 0.00% of their portfolio | 14.6k $268.1k | Added +14.4k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 14.3k $263.3k | New |
| Shay Capital LLC 0.03% of their portfolio | 13.7k $252.1k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 12.0k $221.6k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 10.8k $198.7k | New |
| EntryPoint Capital, LLC 0.05% of their portfolio | 10.8k $198.6k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 10.7k $197.1k | Added +7.9k |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 8.6k $158.8k | Added +1.3k |
| Legal & General Group Plc 0.00% of their portfolio | 8.0k $147.5k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.7k $68.2k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 3.3k $59.9k | New |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 3.0k $54.5k | Reduced -6.1k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 2.4k $44.6k | Added +257 |
| Global Retirement Partners, LLC 0.00% of their portfolio | 2.1k $38.5k | First filing |
| Pinnacle Wealth Planning Services, Inc. 0.00% of their portfolio | 2.0k $36.4k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.7k $32.1k | Reduced -1.7k |
| Winthrop Capital Management, LLC 0.01% of their portfolio | 1.5k $27.0k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 1.3k $23.0k | Added +1.1k |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.1k $19.7k | Added +700 |
| Pacer Advisors, Inc. 0.00% of their portfolio | 815 $15.0k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 562 $10.3k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 355 $6.5k | New |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 308 $5.7k | Added +62 |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 0.00% of their portfolio | 180 $3.3k | New |
| SIGNATUREFD, LLC 0.00% of their portfolio | 147 $2.7k | Added +108 |
| WPG Advisers, LLC 0.00% of their portfolio | 22 $405 | Added +1 |
| Allworth Financial LP 0.00% of their portfolio | 10 $185 | Reduced -63 |
| Parallel Advisors, LLC 0.00% of their portfolio | 5 $92 | Reduced -43 |