ACLARIS THERAPEUTICS INC ACRS
COM · Common Stock · CUSIP 00461U105
Company in St Louis, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWayne, PA
- Founded2012
- Websiteaclaristx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($37.1k this quarter). Holder counts are more reliable. Shares outstanding: 147.2m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $5.29. Options: 6 managers hold calls ($3.4m notional), 4 hold puts ($1.2m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 127 |
| Q4 2022 | 129 |
| Q1 2023 | 150 |
| Q2 2023 | 134 |
| Q3 2023 | 139 |
| Q4 2023 | 108 |
| Q1 2024 | 99 |
| Q2 2024 | 99 |
| Q3 2024 | 82 |
| Q4 2024 | 99 |
| Q1 2025 | 110 |
| Q2 2025 | 97 |
| Q3 2025 | 103 |
| Q4 2025 | 122 |
| Q1 2026 | 136 |
| Q2 2026 | 149 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 29 | 53 |
| Q4 2024 | 54 | 38 |
| Q1 2025 | 59 | 38 |
| Q2 2025 | 52 | 64 |
| Q3 2025 | 41 | 47 |
| Q4 2025 | 55 | 45 |
| Q1 2026 | 70 | 56 |
| Q2 2026 | 96 | 45 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $33.2k | $0 | 0.00 |
| Q4 2025 | $3.5m | $0 | 0.00 |
| Q1 2026 | $2.6m | $1.1m | 0.44 |
| Q2 2026 | $3.4m | $1.2m | 0.35 |
Biggest buyers
| RA CAPITAL MANAGEMENT, L.P. | Added | +5.9m |
| BlackRock, Inc. | Added | +2.6m |
| SILVERARC CAPITAL MANAGEMENT, LLC | New | +1.9m |
| Jones Hill Capital LP | New | +1.8m |
| STATE STREET CORP | Added | +1.2m |
| PANAGORA ASSET MANAGEMENT INC | Added | +853.9k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +766.4k |
| MPM BIOIMPACT LLC | Added | +650.5k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +650.4k |
| Kalehua Capital Management LLC | Added | +494.8k |
Biggest sellers
| MORGAN STANLEY | Reduced | -2.6m |
| BML Capital Management, LLC | Reduced | -2.3m |
| Balyasny Asset Management L.P. | Reduced | -1.3m |
| MARSHALL WACE, LLP | Sold out | -713.0k |
| Monashee Investment Management LLC | Sold out | -500.0k |
| CITADEL ADVISORS LLC | Reduced | -487.2k |
| D. E. Shaw & Co., Inc. | Reduced | -486.3k |
| Logos Global Management LP | Reduced | -300.0k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -262.6k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | Reduced | -255.0k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $2.8m521.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $271.9k51.4k shares |
| SIMPLEX TRADING, LLC | Added | $106.9k20.2k shares |
| Verition Fund Management LLC | New | $105.8k20.0k shares |
| GROUP ONE TRADING LLC | Added | $86.8k16.4k shares |
| JANE STREET GROUP, LLC | Reduced | $54.5k10.3k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $550.2k104.0k shares |
| SIMPLEX TRADING, LLC | Unchanged | $344.9k65.2k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $280.9k53.1k shares |
| GROUP ONE TRADING LLC | Unchanged | $5.8k1.1k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BML Investment Partners, L.P. 13G · passive investor -2.0 pts · filed 2026-04-27 | 9.9% |
| Bonita Biotech (HK) Ltd 13G · passive investor filed 2026-01-09 | 9.4% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor +2.8 pts · filed 2026-08-14 | 9.1% |
| Deep Track Capital, LP 13G · passive investor new · filed 2026-03-17 | 7.0% |
| BlackRock, Inc. 13G · institution +1.1 pts · filed 2026-01-21 | 6.2% |
| Frazier Life Sciences Public Fund, L.P. 13G · passive investor new · filed 2026-09-21 | 5.4% |
Fell to 5% or below in the last year: Vivo Opportunity Fund Holdings, L.P. (4.3%, 2026-05-12), VANGUARD GROUP INC (0.0%, 2026-03-26), Adage Capital Management, L.P. (4.9%, 2025-11-13)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 1 | $1.5m | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-04-23 | Leonard Braden Michael 10% owner · Holdings of BML Investment Partners, L.P. | Sold | $1.4m300.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 0.58% of their portfolio | 12.7m $67.3m | Added +5.9m |
| BML Capital Management, LLC 36.18% of their portfolio | 12.0m $63.3m | Reduced -2.3m |
| BlackRock, Inc. 0.00% of their portfolio | 10.0m $53.1m | Added +2.6m |
| Deep Track Capital, LP 0.73% of their portfolio | 9.3m $49.4m | Unchanged |
| Vivo Capital, LLC 3.23% of their portfolio | 6.7m $35.4m | Added +28.0k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 5.8m $30.8m | Added +650.4k |
| Frazier Life Sciences Management, L.P. 0.57% of their portfolio | 4.9m $26.1m | Unchanged |
| Rock Springs Capital Management LP 1.12% of their portfolio | 4.3m $22.9m | Reduced -142.1k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.03% of their portfolio | 4.1m $21.5m | Added +200.0k |
| Decheng Capital LLC 2.92% of their portfolio | 4.0m $21.4m | Unchanged |
| Kalehua Capital Management LLC 6.18% of their portfolio | 3.7m $19.4m | Added +494.8k |
| STATE STREET CORP 0.00% of their portfolio | 3.3m $17.2m | Added +1.2m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 3.2m $16.9m | Added +766.4k |
| BRAIDWELL LP 0.42% of their portfolio | 2.1m $11.3m | Added +443.2k |
| Balyasny Asset Management L.P. 0.02% of their portfolio | 2.0m $10.7m | Reduced -1.3m |
| SILVERARC CAPITAL MANAGEMENT, LLC 1.15% of their portfolio | 1.9m $10.3m | New |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 1.8m $9.3m | Reduced -487.2k |
| Jones Hill Capital LP 1.98% of their portfolio | 1.8m $9.3m | New |
| ACADIAN ASSET MANAGEMENT LLC 0.01% of their portfolio | 1.6m $8.7m | Added +101.7k |
| Palo Alto Investors LP 1.18% of their portfolio | 1.6m $8.5m | Unchanged |
| Woodline Partners LP 0.03% of their portfolio | 1.6m $8.5m | Added +125.4k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.5m $7.8m | Reduced -190.3k |
| PANAGORA ASSET MANAGEMENT INC 0.02% of their portfolio | 1.4m $7.2m | Added +853.9k |
| Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio | 1.2m $6.4m | Reduced -208.5k |
| MPM BIOIMPACT LLC 0.34% of their portfolio | 1.0m $5.5m | Added +650.5k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 1.0m $5.5m | Added +43.1k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 998.8k $5.3m | Added +270.5k |
| Aldebaran Capital, LLC 3.72% of their portfolio | 936.7k $5.0m | Reduced -10.4k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 907.2k $4.8m | Added +278.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 817.5k $4.3m | Added +314.9k |
| Three Bridge Wealth Advisors, LLC 0.95% of their portfolio | 714.8k $3.8m | Unchanged |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 609.2k $3.2m | Added +20.5k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 523.9k $2.8m | Reduced -232.2k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 513.8k $2.7m | Added +2.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 469.0k $2.4m | Reduced -17.7k |
| Aisling Capital Management LP 0.49% of their portfolio | 434.5k $2.3m | Unchanged |
| Bollard Group LLC 0.07% of their portfolio | 431.6k $2.3m | Unchanged |
| ORBIMED ADVISORS LLC 0.04% of their portfolio | 421.5k $2.2m | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 414.5k $2.2m | Reduced -486.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 412.5k $2.2m | Added +32.6k |
| Tetragon Partners GP Ltd 0.34% of their portfolio | 400.0k $2.1m | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 365.1k $1.9m | Added +56.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 346.1k $1.8m | Added +85.1k |
| FMR LLC 0.00% of their portfolio | 313.9k $1.7m | Added +137.5k |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 309.1k $1.6m | Added +131.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 282.6k $1.5m | Added +75.6k |
| Nuveen, LLC 0.00% of their portfolio | 278.4k $1.5m | Added +160.4k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 275.6k $1.5m | Added +9.2k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 267.5k $1.4m | Added +10.3k |
| SUPERSTRING CAPITAL MANAGEMENT LP 0.86% of their portfolio | 257.7k $1.4m | Reduced -108.8k |
| UBS Group AG 0.00% of their portfolio | 257.0k $1.4m | Added +50.2k |
| Invesco Ltd. 0.00% of their portfolio | 243.0k $1.3m | Added +28.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 221.6k $1.2m | Added +64.9k |
| HighTower Advisors, LLC 0.00% of their portfolio | 217.5k $1.2m | Reduced -88.3k |
| Creative Planning 0.00% of their portfolio | 206.6k $1.1m | Added +54.6k |
| Logos Global Management LP 0.05% of their portfolio | 200.0k $1.1m | Reduced -300.0k |
| Verdad Advisers, LP 0.89% of their portfolio | 175.3k $927.2k | Reduced -21.8k |
| Informed Momentum Co LLC 0.08% of their portfolio | 171.3k $906.3k | Reduced -7.1k |
| Atom Investors LP 0.07% of their portfolio | 148.9k $787.4k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 143.2k $757.6k | Added +67.8k |
| ALPS ADVISORS INC 0.00% of their portfolio | 141.7k $749.9k | Added +43.6k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 138.8k $734.1k | Reduced -78.4k |
| MORGAN STANLEY 0.00% of their portfolio | 134.1k $709.5k | Reduced -2.6m |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 133.1k $703.9k | Reduced -262.6k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 129.1k $682.7k | Added +60.3k |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 120.0k $634.8k | Added +103.2k |
| CenterBook Partners LP 0.03% of their portfolio | 118.2k $625.4k | Added +51.6k |
| CITIGROUP INC 0.00% of their portfolio | 117.8k $623.1k | Added +110.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 110.4k $584.1k | Added +30.9k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 108.6k $574.7k | Added +72.4k |
| Verition Fund Management LLC 0.00% of their portfolio | 98.0k $518.4k | New |
| Cambridge Investment Research Advisors, Inc. 0.00% of their portfolio | 83.7k $444.0k | Added +41.9k |
| STRS OHIO 0.00% of their portfolio | 81.4k $430.6k | Added +65.4k |
| Voleon Capital Management LP 0.01% of their portfolio | 77.2k $408.2k | New |
| Susquehanna Portfolio Strategies, LLC 0.01% of their portfolio | 76.3k $403.5k | Added +36.6k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 75.0k $396.9k | Reduced -255.0k |
| BARCLAYS PLC 0.00% of their portfolio | 73.0k $386.2k | Added +51.5k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 69.7k $368.7k | Added +25.8k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 60.3k $318.8k | Reduced -12.1k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 57.0k $213.8k | Added +41.8k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 54.6k $288.7k | Added +11.0k |
| MANGROVE PARTNERS IM, LLC 0.02% of their portfolio | 50.3k $266.0k | New |
| DIVERSIFIED TRUST CO 0.00% of their portfolio | 45.5k $240.8k | Added +16.1k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 38.8k $205.4k | Added +19.1k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 35.5k $187.9k | Added +14.1k |
| SG Americas Securities, LLC 0.00% of their portfolio | 34.8k $184.0k | Added +8.0k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 32.4k $171.4k | Added +7.0k |
| PROFUND ADVISORS LLC 0.00% of their portfolio | 30.5k $161.3k | New |
| State of Wyoming 0.01% of their portfolio | 27.4k $145.2k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 27.3k $144.4k | Unchanged |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 24.7k $130.5k | Added +5.5k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 23.1k $122.2k | Added +6.8k |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 22.2k $117.6k | Added +827 |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 22.0k $116.4k | New |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 20.3k $107.2k | Added +6.9k |
| ProShare Advisors LLC 0.00% of their portfolio | 20.1k $106.3k | Added +1.4k |
| Walleye Capital LLC 0.00% of their portfolio | 19.6k $103.6k | New |
| NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio | 19.4k $102.5k | Reduced -2.7k |
| Vontobel Holding Ltd. 0.00% of their portfolio | 18.0k $95.2k | Reduced -7.0k |
| CRA Financial Services, LLC 0.01% of their portfolio | 17.8k $94.1k | Unchanged |