Affinity Asset Advisors, LLC

NEW YORK, NY · CIK 1773195 · 13F filing filed 2026-08-13

SEC-registered investment adviser since 2021 · limited liability company

Assets managed$2.5bn
Staff10 · 7 in investment roles
Main clients (by assets)Private funds 100%
Private funds2 (1 hedge) · $2.5bn gross assets
Websiteaffinityadv.com
Form ADV · 2026-07-27SEC adviser record

Legal entityAFFINITY ASSET ADVISORS, LLC (US)

$2.0bn reported value +19.9% vs Q1 2026

104positions

42.6%in top 10

19 new 33 added 28 reduced 10 sold out vs Q1 2026

Options: 6 call positions ($112.6m notional), 3 put positions ($55.1m notional) – listed below, not included above.

Holdings, Q2 2026

The small lines show how much was held over the last 4 quarters (adjusted for stock splits).

#	Security	Ticker	Shares	Value	% of portfolio	Change	Shares change
1	ROIVANT SCIENCES LTD SHS ROIV	ROIV	3,750,000	$132.7m6.49%	6.49%	Added +950.0k	+950,000 33.9%
2	APOGEE THERAPEUTICS INC COM COM		987,000	$131.0m6.41%	6.41%	Reduced -297.9k	-297,926 -23.2%
3	SPYRE THERAPEUTICS INC COM NEW SYRE	SYRE	1,279,134	$113.6m5.55%	5.55%	Unchanged
4	XENON PHARMACEUTICALS INC COM XENE	XENE	1,595,000	$96.3m4.71%	4.71%	Reduced -80.0k	-80,000 -4.8%
5	ERASCA INC COM ERAS	ERAS	5,250,000	$96.2m4.70%	4.70%	Reduced -100.0k	-100,000 -1.9%
6	INSMED INC COM PAR $.01 INSM	INSM	650,000	$69.3m3.39%	3.39%	Added +170.0k	+170,000 35.4%
7	PRAXIS PRECISION MEDICINES I COM NEW PRAX	PRAX	185,000	$61.9m3.03%	3.03%	Added +15.0k	+15,000 8.8%
8	ALKERMES PLC SHS ALKS	ALKS	1,125,000	$58.9m2.88%	2.88%	Reduced -225.0k	-225,000 -16.7%
9	ORUKA THERAPEUTICS INC COM ORKA	ORKA	590,000	$56.2m2.75%	2.75%	Added +90.3k	+90,327 18.1%
10	ANAPTYSBIO INC COM ANAB	ANAB	826,109	$55.8m2.73%	2.73%	Reduced -113.9k	-113,891 -12.1%
11	AVALO THERAPEUTICS INC COM NEW AVTX	AVTX	2,900,000	$53.6m2.62%	2.62%	Added +1.6m	+1,559,160 116.3%
12	CYTOKINETICS INC COM NEW CYTK	CYTK	550,000	$46.9m2.29%	2.29%	Reduced -150.5k	-150,483 -21.5%
13	REVOLUTION MEDICINES INC COM RVMD	RVMD	250,000	$46.8m2.29%	2.29%	Added +150.0k	+150,000 150.0%
14	ABIVAX SA SPONSORED ADS ABVX	ABVX	330,000	$44.0m2.15%	2.15%	Reduced -75.0k	-75,000 -18.5%
15	FIRST TRACKS BIOTHERAPEUTICS ORD SHS TRAX	TRAX	2,032,012	$40.9m2.00%	2.00%	New
16	DIANTHUS THERAPEUTICS INC COM DNTH	DNTH	400,000	$39.0m1.91%	1.91%	Added +50.0k	+50,000 14.3%
17	SUTRO BIOPHARMA INC COM SHS STRO	STRO	1,172,487	$38.9m1.90%	1.90%	Added +103.0k	+102,968 9.6%
18	NUVALENT INC COM COM		275,000	$34.0m1.66%	1.66%	Reduced -25.0k	-25,000 -8.3%
19	TREVI THERAPEUTICS INC COM TRVI	TRVI	1,800,172	$33.6m1.64%	1.64%	Reduced -200.0k	-200,000 -10.0%
20	OVID THERAPEUTICS INC COM OVID	OVID	10,144,562	$27.3m1.33%	1.33%	Reduced -491.8k	-491,756 -4.6%
21	LEXEO THERAPEUTICS INC COM LXEO	LXEO	5,807,611	$27.0m1.32%	1.32%	Added +757.4k	+757,400 15.0%
22	CELLDEX THERAPEUTICS INC NEW COM NEW CLDX	CLDX	700,000	$26.0m1.27%	1.27%	Added +200.0k	+200,000 40.0%
23	BELITE BIO INC SPONSORED ADS BLTE	BLTE	165,000	$25.4m1.24%	1.24%	Added +100.0k	+100,000 153.8%
24	ENLIVEN THERAPEUTICS INC COM ELVN	ELVN	500,000	$25.4m1.24%	1.24%	Reduced -86.9k	-86,904 -14.8%
25	FORTE BIOSCIENCES INC COM NEW FBRX	FBRX	1,145,391	$24.3m1.19%	1.19%	Added +133.5k	+133,501 13.2%
26	NURIX THERAPEUTICS INC COM NRIX	NRIX	967,620	$23.5m1.15%	1.15%	Unchanged
27	ALTO NEUROSCIENCE INC COM SHS ANRO	ANRO	850,000	$22.4m1.10%	1.10%	Added +350.0k	+350,000 70.0%
28	MADRIGAL PHARMACEUTICALS INC COM MDGL	MDGL	40,000	$21.5m1.05%	1.05%	Reduced -15.0k	-15,000 -27.3%
29	PROTAGONIST THERAPEUTICS INC COM PTGX	PTGX	172,125	$21.1m1.03%	1.03%	Unchanged
30	MINERALYS THERAPEUTICS INC COM MLYS	MLYS	750,000	$20.2m0.99%	0.99%	Unchanged
31	RELAY THERAPEUTICS INC COM RLAY	RLAY	1,050,000	$19.6m0.96%	0.96%	Added +650.0k	+650,000 162.5%
32	SAGIMET BIOSCIENCES INC COM SER A SGMT	SGMT	2,497,864	$19.3m0.94%	0.94%	Added +1.6m	+1,629,844 187.8%
33	JADE BIOSCIENCES INC COM NEW JBIO	JBIO	840,350	$18.7m0.91%	0.91%	Added +200.4k	+200,394 31.3%
34	COGENT BIOSCIENCES INC COM COGT	COGT	450,000	$17.4m0.85%	0.85%	Reduced -300.0k	-300,000 -40.0%
35	TRAVERE THERAPEUTICS INC COM TVTX	TVTX	300,000	$17.0m0.83%	0.83%	Unchanged
36	CULLINAN THERAPEUTICS INC COM CGEM	CGEM	875,760	$15.9m0.78%	0.78%	Added +94.5k	+94,500 12.1%
37	SAVARA INC COM SVRA	SVRA	2,512,153	$15.5m0.76%	0.76%	Unchanged
38	IDEAYA BIOSCIENCES INC COM IDYA	IDYA	400,000	$14.9m0.73%	0.73%	New
39	PERSPECTIVE THERAPEUTICS INC COM NEW CATX	CATX	4,214,582	$14.4m0.70%	0.70%	Added +1.1m	+1,050,000 33.2%
40	ODYSSEY THERAPEUTICS INC COMMON STOCK ODTX	ODTX	766,346	$14.3m0.70%	0.70%	New
41	COGENT BIOSCIENCES INC NOTE 1.625%11/1 · principal COGT 1.625 11.15.31 · principal	COGT 1.625 11.15.31	11,000,000	$13.7m0.67%	0.67%	Added +4.0m	+4,000,000 57.1%
42	HELIX ACQUISITION CORP III USD CL A ORD SHS HLXC	HLXC	1,250,000	$13.3m0.65%	0.65%	Unchanged
43	EQUILLIUM INC COM EQ	EQ	4,100,000	$13.1m0.64%	0.64%	Added +2.9m	+2,873,690 234.3%
44	ESTABLISHMENT LABS HLDGS INC COM ESTA	ESTA	148,013	$12.7m0.62%	0.62%	Added +48.0k	+48,013 48.0%
45	CLIMB BIO INC COM CLYM	CLYM	972,000	$12.7m0.62%	0.62%	Added +272.0k	+272,000 38.9%
46	TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS SPONSORED ADS		374,000	$12.7m0.62%	0.62%	Reduced -1.0m	-1,026,000 -73.3%
47	VERADERMICS INC COMMON STOCK MANE	MANE	100,000	$12.3m0.60%	0.60%	Added +30.0k	+30,000 42.9%
48	ARROWHEAD PHARMACEUTICALS IN COM ARWR	ARWR	150,000	$12.2m0.60%	0.60%	Reduced -50.0k	-50,000 -25.0%
49	OMEROS CORP NOTE 9.500% 6/1 · principal OMER 9.5 06.15.29 · principal	OMER 9.5 06.15.29	6,525,000	$12.2m0.60%	0.60%	Unchanged
50	TAYSHA GENE THERAPIES INC COM SHS TSHA	TSHA	1,750,000	$11.9m0.58%	0.58%	Added +750.0k	+750,000 75.0%
51	DAMORA THERAPEUTICS INC COM NEW COM NEW		425,000	$11.1m0.54%	0.54%	Reduced -25.0k	-25,000 -5.6%
52	EUPRAXIA PHARMACEUTICALS INC COM EPRX	EPRX	1,650,000	$10.9m0.53%	0.53%	Added +61.0k	+60,995 3.8%
53	VERA THERAPEUTICS INC CL A VERA	VERA	250,000	$10.7m0.52%	0.52%	Unchanged
54	PROQR THRAPEUTICS N V SHS EURO PRQR	PRQR	5,543,936	$10.3m0.50%	0.50%	Added +3.1m	+3,089,658 125.9%
55	NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES NAMS	NAMS	275,000	$9.3m0.46%	0.46%	Unchanged
56	KORRO BIO INC COM KRRO	KRRO	706,904	$9.3m0.46%	0.46%	Unchanged
57	ANTERIS TECHNOLOGIES GLOBAL COM AVR	AVR	912,397	$9.0m0.44%	0.44%	Unchanged
58	ZURA BIO LTD CLASS A ORD SHS ZURA	ZURA	1,464,303	$8.6m0.42%	0.42%	Reduced -1.1m	-1,100,000 -42.9%
59	UNIQURE NV SHS QURE	QURE	175,000	$8.1m0.39%	0.39%	New
60	ASCENDIS PHARMA A/S ORD SHS ASND	ASND	30,000	$8.0m0.39%	0.39%	New
61	IBIO INC COM NEW IBIO	IBIO	4,007,881	$7.0m0.34%	0.34%	Added +900.7k	+900,681 29.0%
62	GENERATE BIOMEDICINES INC COM SHS GENB	GENB	400,000	$6.7m0.33%	0.33%	Added +50.0k	+50,000 14.3%
63	TYRA BIOSCIENCES INC COM TYRA	TYRA	200,012	$6.4m0.31%	0.31%	Reduced -57.5k	-57,500 -22.3%
64	SOL-GEL TECHNOLOGIES LTD SHS NEW SLGL	SLGL	84,900	$6.3m0.31%	0.31%	Added +49.9k	+49,900 142.6%
65	SAB BIOTHERAPEUTICS INC COM NEW SABS	SABS	1,525,000	$5.9m0.29%	0.29%	Added +950.0k	+950,000 165.2%
66	MACROGENICS INC COM MGNX	MGNX	1,216,606	$5.6m0.27%	0.27%	Added +716.6k	+716,606 143.3%
67	CRISPR THERAPEUTICS AG NAMEN AKT CRSP	CRSP	100,000	$5.5m0.27%	0.27%	Reduced -50.0k	-50,000 -33.3%
68	NEWAMSTERDAM PHARMA COMPANY *W EXP 11/22/202 NAMSW	NAMSW	245,000	$5.3m0.26%	0.26%	Unchanged
69	ASSEMBLY BIOSCIENCES INC COM NEW ASMB	ASMB	190,000	$5.2m0.26%	0.26%	New
70	REZOLUTE INC COM NEW RZLT	RZLT	1,000,000	$5.2m0.25%	0.25%	Reduced -547.6k	-547,641 -35.4%
71	PRECISION BIOSCIENCES INC COM NEW DTIL	DTIL	646,576	$5.1m0.25%	0.25%	Added +48.6k	+48,630 8.1%
72	HEMAB THERAPEUTICS HLDGS INC COM SHS COAG	COAG	138,030	$5.1m0.25%	0.25%	New
73	VIRIDIAN THERAPEUTICS INC COM VRDN	VRDN	250,000	$4.6m0.22%	0.22%	Unchanged
74	ARRIVENT BIOPHARMA INC COM AVBP	AVBP	125,000	$4.3m0.21%	0.21%	Reduced -50.0k	-50,000 -28.6%
75	VERRICA PHARMACEUTICALS INC COM SHS VRCA	VRCA	707,338	$4.3m0.21%	0.21%	Unchanged
76	COMPASS PATHWAYS PLC SPONSORED ADS CMPS	CMPS	301,183	$4.3m0.21%	0.21%	Reduced -807.3k	-807,300 -72.8%
77	MBX BIOSCIENCES INC COM MBX	MBX	75,000	$4.1m0.20%	0.20%	Reduced -75.0k	-75,000 -50.0%
78	RESEARCH ALLIANCE CORP III ORD SHS CL A RACC	RACC	370,000	$4.0m0.19%	0.19%	New
79	IMMUNOVANT INC COM IMVT	IMVT	100,000	$3.9m0.19%	0.19%	Unchanged
80	AMANAT ACQUISITION CORP CL A ORD AMAN	AMAN	375,000	$3.8m0.19%	0.19%	New
81	BIOHAVEN LTD COM BHVN	BHVN	250,000	$3.7m0.18%	0.18%	New
82	FAETH THERAPEUTICS INC COM NEW FTH	FTH	144,404	$3.6m0.18%	0.18%	New
83	KARYOPHARM THERAPEUTICS INC COM NEW KPTI	KPTI	312,500	$3.1m0.15%	0.15%	Reduced -187.5k	-187,500 -37.5%
84	ALECTOR INC COM ALEC	ALEC	1,510,000	$3.0m0.15%	0.15%	Added +1.0m	+1,010,000 202.0%
85	SPYGLASS PHARMA INC COM SHS SGP	SGP	131,586	$2.9m0.14%	0.14%	Reduced -118.4k	-118,414 -47.4%
86	CRINETICS PHARMACEUTICALS IN COM CRNX	CRNX	75,000	$2.8m0.14%	0.14%	Unchanged
87	OAKTREE ACQUISITION CORP III UNIT 10/04/2029 OACCU	OACCU	250,000	$2.8m0.13%	0.13%	Unchanged
88	CELCUITY INC NOTE 0.250% 8/0 · principal CELC 0.25 08.01.32 · principal	CELC 0.25 08.01.32	2,000,000	$2.3m0.11%	0.11%	New
89	JATT II ACQUISITION CORP ORD SHS JATT	JATT	200,000	$2.3m0.11%	0.11%	New
90	NEUMORA THERAPEUTICS INC. COM NMRA	NMRA	1,070,651	$1.8m0.09%	0.09%	New
91	AMYLYX PHARMACEUTICALS INC COM AMLX	AMLX	98,999	$1.8m0.09%	0.09%	New
92	ADLAI NORTYE LTD SPONSORED ADS ANL	ANL	153,847	$1.8m0.09%	0.09%	Reduced -10.9k	-10,901 -6.6%
93	SPRUCE BIOSCIENCES INC COM NEW SPRB	SPRB	30,000	$1.6m0.08%	0.08%	New
94	EIKON THERAPEUTICS INC COM EIKN	EIKN	98,001	$1.3m0.06%	0.06%	New
95	ONKURE THERAPEUTICS INC COM CL A OKUR	OKUR	240,963	$1.1m0.05%	0.05%	Unchanged
96	ENGENE THERAPEUTICS INC COM ENGN	ENGN	600,000	$1.0m0.05%	0.05%	New
97	X4 PHARMACEUTICALS INC COM NEW XFOR	XFOR	145,000	$677.1k0.03%	0.03%	Unchanged
98	BOUNDLESS BIO INC COM BOLD	BOLD	250,000	$625.0k0.03%	0.03%	New
99	LENZ THERAPEUTICS INC COM LENZ	LENZ	100,000	$568.0k0.03%	0.03%	Unchanged
100	Q32 BIO INC COM QTTB	QTTB	27,777	$353.9k0.02%	0.02%	Unchanged

Sold out since Q1 2026

Security	Ticker	Shares held before	Value then
CENTESSA PHARMACEUTICALS PLC		1,400,000	$55.6m1.4m shares
ARCELLX INC ACLX	ACLX	362,764	$41.7m362.8k shares
TERNS PHARMACEUTICALS INC		562,631	$29.7m562.6k shares
ASCENDIS PHARMA A/S		95,000	$21.7m95.0k shares
BRIDGEBIO PHARMA INC BBIO	BBIO	150,000	$11.1m150.0k shares
WAVE LIFE SCIENCES LTD 96663EUR	96663EUR	1,401,727	$10.2m1.4m shares
CELCUITY INC CELC 2.75 08.01.31	CELC 2.75 08.01.31	3,000,000	$7.3m3.0m shares
ENGENE HOLDINGS INC		610,370	$4.2m610.4k shares
CORCEPT THERAPEUTICS INC CORT	CORT	50,000	$2.0m50.0k shares
KEZAR LIFE SCIENCES INC KZR	KZR	229,076	$1.7m229.1k shares

Options (notional value)

Underlying	Ticker	Type	Shares controlled	Notional	Change
MODERNA INC MRNA · Put	MRNA	Put	500,000	$35.0m500.0k shares	New
MODERNA INC MRNA · Call	MRNA	Call	475,000	$33.3m475.0k shares	Reduced
ARK ETF TR ARKG · Call	ARKG	Call	750,000	$31.5m750.0k shares	New
ELI LILLY & CO LLY · Call	LLY	Call	20,000	$24.0m20.0k shares	New
OMEROS CORP OMER · Put	OMER	Put	1,411,300	$13.4m1.4m shares	New
ALKERMES PLC ALKS · Call	ALKS	Call	250,000	$13.1m250.0k shares	New
UNIQURE NV QURE · Call	QURE	Call	200,000	$9.2m200.0k shares	Reduced
EVOMMUNE INC EVMN · Put	EVMN	Put	500,100	$6.6m500.1k shares	New
SUMMIT THERAPEUTICS INC SMMT · Call	SMMT	Call	100,000	$1.5m100.0k shares	New

Stakes above 5%

Companies where this manager has reported owning more than 5% of a class of shares, on Schedule 13D (may seek influence) or 13G (passive): its latest filing for each, from 19 Dec 2024 on.

Company	Ticker	Stake	Change	Schedule	Last filed
IBIO INC IBIO · 13G · filed 2026-08-13	IBIO	10.0%≈ $8.9m	no change	13G	2026-08-13
KARYOPHARM THERAPEUTICS INC KPTI · 13G · filed 2026-05-14	KPTI	8.6%≈ $20.3m	no change	13G	2026-05-14
LEXEO THERAPEUTICS INC LXEO · 13G · filed 2026-08-13	LXEO	8.4%≈ $31.1m	+1.3 pts	13G	2026-08-13
OVID THERAPEUTICS INC OVID · 13G · filed 2026-08-13	OVID	7.9%≈ $40.7m	-1.2 pts	13G	2026-08-13
SUTRO BIOPHARMA INC 13G · filed 2025-10-23		7.8%	new	13G	2025-10-23
HELIX ACQUISITION CORP III HLXC · 13G · filed 2026-05-14	HLXC	7.0%≈ $13.3m	new	13G	2026-05-14
EQUILLIUM INC EQ · 13G · filed 2026-08-13	EQ	6.5%≈ $13.1m	new	13G	2026-08-13
SUTRO BIOPHARMA INC STRO · 13G · filed 2026-05-14	STRO	6.5%≈ $35.5m	-2.3 pts	13G	2026-05-14
NEXTCURE INC NXTC · 13G · filed 2026-08-13	NXTC	6.4%≈ $438.5k	-3.6 pts	13G	2026-08-13
FIRST TRACKS BIOTHERAPEUTICS TRAX · 13G · filed 2026-08-13	TRAX	5.8%≈ $40.9m	new	13G	2026-08-13
FORTE BIOSCIENCES INC FBRX · 13G · filed 2026-08-13	FBRX	5.6%≈ $24.3m	-1.7 pts	13G	2026-08-13
AVALO THERAPEUTICS INC AVTX · 13G · filed 2026-08-13	AVTX	5.5%≈ $53.6m	no change	13G	2026-08-13
VERRICA PHARMACEUTICALS INC VRCA · 13G · filed 2026-01-29	VRCA	5.5%≈ $5.4m	no change	13G	2026-01-29
AMANAT ACQUISITION CORP AMAN · 13G · filed 2026-08-13	AMAN	5.0%≈ $3.8m	new	13G	2026-08-13