Vault-13

INSMED INC INSM

COM PAR $.01 · Common Stock · CUSIP 457669307 · ISIN US4576693075

665 institutional holders -9 vs Q1 2026
223,585,574223.6m shares reported held*
102.4% of all shares outstanding*
$23.8bnreported value*
111 new 245 added 231 reduced 121 sold out net sold ≈ $371.5m (-3.7m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($31.0m this quarter). Holder counts are more reliable. Shares outstanding: 218.4m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $106.60. Options: 34 managers hold calls ($613.6m notional), 26 hold puts ($414.6m).

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

0250500750Q3 22: 239Q4 22: 226Q1 23: 232Q2 23: 225Q3 23: 254Q4 23: 273Q1 24: 290Q2 24: 380Q3 24: 417Q4 24: 441Q1 25: 444Q2 25: 518Q3 25: 566Q4 25: 677Q1 26: 674Q2 26: 665665Q3 22Q3 23Q3 24Q3 25Q2 26
Numbers
QuarterHolders
Q3 2022239
Q4 2022226
Q1 2023232
Q2 2023225
Q3 2023254
Q4 2023273
Q1 2024290
Q2 2024380
Q3 2024417
Q4 2024441
Q1 2025444
Q2 2025518
Q3 2025566
Q4 2025677
Q1 2026674
Q2 2026665

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
5000500Q3 24: 257 bought or addedQ3 24: 152 cut or sold outQ4 24: 226 bought or addedQ4 24: 188 cut or sold outQ4 24Q1 25: 236 bought or addedQ1 25: 195 cut or sold outQ2 25: 290 bought or addedQ2 25: 242 cut or sold outQ2 25Q3 25: 320 bought or addedQ3 25: 264 cut or sold outQ4 25: 403 bought or addedQ4 25: 263 cut or sold outQ4 25Q1 26: 377 bought or addedQ1 26: 307 cut or sold outQ2 26: 356 bought or addedQ2 26: 352 cut or sold outQ2 26
Numbers
QuarterBought or addedCut or sold out
Q3 2024257152
Q4 2024226188
Q1 2025236195
Q2 2025290242
Q3 2025320264
Q4 2025403263
Q1 2026377307
Q2 2026356352

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$200m$400m$600m$800mQ3 25 calls: $640.6mQ3 25 puts: $658.6mQ3 25P/C 1.03Q4 25 calls: $673.7mQ4 25 puts: $741.7mQ4 25P/C 1.10Q1 26 calls: $352.2mQ1 26 puts: $231.9mQ1 26P/C 0.66Q2 26 calls: $613.6mQ2 26 puts: $414.6mQ2 26P/C 0.68
Numbers
QuarterCallsPutsP/C
Q3 2025$640.6m$658.6m1.03
Q4 2025$673.7m$741.7m1.10
Q1 2026$352.2m$231.9m0.66
Q2 2026$613.6m$414.6m0.68

Biggest buyers

Orbis Allan Gray Ltd Added +4,203,663+4.2m
AMERIPRISE FINANCIAL INC Added +3,121,853+3.1m
FMR LLC Added +2,983,416+3.0m
Capital International Investors Added +2,642,930+2.6m
MAVERICK CAPITAL LTD New +2,150,762+2.2m
T. Rowe Price Investment Management, Inc. New +1,622,675+1.6m
Qube Research & Technologies Ltd Added +1,533,819+1.5m
Bellevue Group AG Added +1,383,384+1.4m
BAKER BROS. ADVISORS LP Added +1,375,000+1.4m
Balyasny Asset Management L.P. Added +1,104,723+1.1m

Biggest sellers

JPMORGAN CHASE & CO Reduced -13,722,329-13.7m
Darwin Global Management, Ltd. Reduced -10,374,021-10.4m
Invesco Ltd. Reduced -6,144,628-6.1m
Capital World Investors Sold out -1,362,291-1.4m
Artisan Partners Limited Partnership Reduced -1,085,583-1.1m
NWI MANAGEMENT LP Reduced -1,014,000-1.0m
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. Reduced -924,616-924.6k
BlackRock, Inc. Reduced -870,162-870.2k
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC Sold out -653,445-653.4k
FEDERATED HERMES, INC. Reduced -538,127-538.1k

Biggest calls

Duquesne Family Office LLC New $143.9m1.4m shares
MILLENNIUM MANAGEMENT LLC Added $92.1m864.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $76.3m715.6k shares
Caption Management, LLC Added $67.2m630.0k shares
JANE STREET GROUP, LLC Added $48.2m451.7k shares
JPMORGAN CHASE & CO Added $47.7m455.0k shares
CITADEL ADVISORS LLC Reduced $38.1m357.2k shares
TUDOR INVESTMENT CORP ET AL Added $33.1m310.3k shares
Eversept Partners, LP Added $10.3m96.6k shares
GOLDMAN SACHS GROUP INC New $8.9m83.8k shares

Biggest puts

GOLDMAN SACHS GROUP INC New $81.9m767.9k shares
Caption Management, LLC Added $79.0m740.7k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $76.7m719.1k shares
JPMORGAN CHASE & CO New $45.0m430.0k shares
JANE STREET GROUP, LLC Added $37.0m346.8k shares
CITADEL ADVISORS LLC Added $29.2m273.7k shares
IMC-Chicago, LLC Added $15.3m143.4k shares
Jefferies Financial Group Inc. Added $11.2m105.4k shares
Parallax Volatility Advisers, L.P. Unchanged $10.9m102.3k shares
CANTOR FITZGERALD, L. P. New $5.3m50.0k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
FMR LLC 13G · institution +1.3 pts · filed 2026-08-06 7.4% +1.3 pts 16.1m≈ $1.7bn 2026-08-06
BlackRock, Inc. 13G · institution +1.5 pts · filed 2026-01-21 6.6% +1.5 pts 14.1m≈ $1.5bn 2026-01-21
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 5.3% new 11.5m≈ $1.2bn 2026-04-30

Fell to 5% or below in the last year: Darwin Global Management, Ltd. (3.0%, 2026-08-14), JPMORGAN CHASE & CO (4.7%, 2026-07-22), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC), PRICE T ROWE ASSOCIATES INC /MD/ (3.3%, 2025-11-14)

Insider purchases and sales since 1 Apr 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
10010Q4 24: 0 buyingQ4 24: 1 sellingQ1 25: 0 buyingQ1 25: 7 sellingQ1 25Q2 25: 1 buyingQ2 25: 7 sellingQ3 25: 0 buyingQ3 25: 7 sellingQ3 25Q4 25: 0 buyingQ4 25: 7 sellingQ1 26: 0 buyingQ1 26: 6 sellingQ1 26Q2 26: 0 buyingQ2 26: 5 sellingQ3 26: 0 buyingQ3 26: 5 sellingQ3 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20240—1$3.7m$3.7m
Q1 20250—7$53.0m$32.1m
Q2 20251$201.7k7$54.6m$49.9m
Q3 20250—7$65.6m$57.2m
Q4 20250—7$44.3m$16.7m
Q1 20260—6$45.2m$40.6m
Q2 20260—5$34.7m$29.5m
Q3 20260—5$42.9m$7.2m
DateInsiderTradeSharesPrice ValueTheir holding
2026-09-09 Brennan David R Director Sold 25,000 $124.00 $3.1m25.0k shares -39%
2026-08-17 SHAROKY MELVIN MD Director · By Padonia, LLC Sold 5,000 $127.53 $637.6k5.0k shares -100%
2026-08-10 Adsett Roger Chief Operating Officer Sold 239,850 $133.27 $32.0m239.8k shares -71%
2026-08-06 Flammer Martina M.D. Chief Medical Officer Sold plan 27,173 $128.61 $3.5m27.2k shares -31%
2026-07-23 Lewis William Chair and CEO, director Sold plan 10,700 $106.06 $1.1m10.7k shares -4%
2026-07-09 Lewis William Chair and CEO, director Sold plan 10,699 $117.40 $1.3m10.7k shares -4%
2026-07-06 Flammer Martina M.D. Chief Medical Officer Sold plan 12,302 $109.98 $1.4m12.3k shares -17%
2026-06-25 Lewis William Chair and CEO, director Sold plan 21,398 $103.32 $2.2m21.4k shares -8%
2026-06-22 Smith Michael Alexander Chief Legal Officer Sold plan 1,806 $95.82 $173.1k1.8k shares -5%
2026-06-08 Lewis William Chair and CEO, director Sold plan 6,515 $94.03 $612.6k6.5k shares -2%
2026-06-05 Flammer Martina M.D. Chief Medical Officer Sold plan 1,858 $103.78 $192.8k1.9k shares -3%
2026-06-03 Lewis William Chair and CEO, director Sold 7,605 $102.27 $777.8k7.6k shares -3%
2026-06-03 Flammer Martina M.D. Chief Medical Officer Sold plan 2,566 $102.27 $262.4k2.6k shares -4%
2026-06-03 Bonstein Sara Chief Financial Officer Sold 2,404 $102.27 $245.9k2.4k shares -3%
2026-06-03 Adsett Roger Chief Operating Officer Sold 2,370 $102.27 $242.4k2.4k shares -2%
2026-06-03 Smith Michael Alexander Chief Legal Officer Sold 2,159 $102.27 $220.8k2.2k shares -5%
2026-05-22 Smith Michael Alexander Chief Legal Officer Sold plan 6,149 $108.47 $667.0k6.1k shares -13%
2026-05-18 Lewis William Chair and CEO, director Sold plan 25,564 $106.33 $2.7m25.6k shares -9%
2026-05-14 Flammer Martina M.D. Chief Medical Officer Sold plan 10,479 $117.54 $1.2m10.5k shares -14%
2026-05-13 Lewis William Chair and CEO, director Sold 13,283 $116.18 $1.5m13.3k shares -4%
2026-05-13 Bonstein Sara Chief Financial Officer Sold 8,272 $116.18 $961.0k8.3k shares -10%
2026-05-13 Flammer Martina M.D. Chief Medical Officer Sold plan 7,854 $114.23 $897.2k7.9k shares -9%
2026-05-13 Adsett Roger Chief Operating Officer Sold 5,837 $116.18 $678.1k5.8k shares -6%
2026-05-13 Smith Michael Alexander Chief Legal Officer Sold 4,109 $116.18 $477.4k4.1k shares -8%
2026-05-11 Flammer Martina M.D. Chief Medical Officer Sold plan 12,949 $100.40 $1.3m12.9k shares -14%
2026-05-04 Lewis William Chair and CEO, director Sold plan 10,699 $137.34 $1.5m10.7k shares -3%
2026-04-16 Lewis William Chair and CEO, director Sold plan 10,699 $143.97 $1.5m10.7k shares -3%
2026-04-06 Lewis William Chair and CEO, director Sold plan 10,699 $163.22 $1.7m10.7k shares -3%
2026-04-01 Adsett Roger Chief Operating Officer Sold plan 88,060 $164.63 $14.5m88.1k shares -45%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FMR LLC 0.07% of their portfolio BOSTON, MA 16,143,58316.1m $1.7bn $1.7bn 0.07% Added +3.0m +2,983,416
2 BlackRock, Inc. 0.03% of their portfolio New York, NY 15,807,98415.8m $1.7bn $1.7bn 0.03% Reduced -870.2k -870,162
3 JPMORGAN CHASE & CO 0.06% of their portfolio NEW YORK, NY 10,428,17010.4m $1.1bn $1.1bn 0.06% Reduced -13.7m -13,722,329
4 VANGUARD PORTFOLIO MANAGEMENT LLC 0.05% of their portfolio MALVERN, PA 10,407,96210.4m $1.1bn $1.1bn 0.05% Added +36.2k +36,160
5 VANGUARD CAPITAL MANAGEMENT LLC 0.02% of their portfolio MALVERN, PA 9,790,8659.8m $1.0bn $1.0bn 0.02% Added +148.7k +148,734
6 BAKER BROS. ADVISORS LP 4.70% of their portfolio NEW YORK, NY 8,796,1118.8m $937.8m $937.8m 4.70% Added +1.4m +1,375,000
7 Capital International Investors 0.18% of their portfolio Los Angeles, CA 8,238,1248.2m $878.3m $878.3m 0.18% Added +2.6m +2,642,930
8 Darwin Global Management, Ltd. 17.91% of their portfolio ST. HELIER, Y9 6,431,1636.4m $673.6m $673.6m 17.91% Reduced -10.4m -10,374,021
9 AMERIPRISE FINANCIAL INC 0.13% of their portfolio MINNEAPOLIS, MN 6,179,5716.2m $658.9m $658.9m 0.13% Added +3.1m +3,121,853
10 Orbis Allan Gray Ltd 2.23% of their portfolio HamiltoN, D0 6,076,4876.1m $647.9m $647.9m 2.23% Added +4.2m +4,203,663
11 STATE STREET CORP 0.02% of their portfolio BOSTON, MA 6,052,1746.1m $645.3m $645.3m 0.02% Added +500.5k +500,475
12 D. E. Shaw & Co., Inc. 0.39% of their portfolio New York, NY 5,877,9595.9m $626.7m $626.7m 0.39% Added +252.1k +252,134
13 Artisan Partners Limited Partnership 0.95% of their portfolio Milwaukee, WI 5,441,7185.4m $580.2m $580.2m 0.95% Reduced -1.1m -1,085,583
14 RTW INVESTMENTS, LP 4.41% of their portfolio NEW YORK, NY 4,842,8804.8m $516.3m $516.3m 4.41% Unchanged
15 GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio BOSTON, MA 4,220,1554.2m $448.8m $448.8m 0.02% Reduced -230.2k -230,234
16 PRICE T ROWE ASSOCIATES INC /MD/ 0.04% of their portfolio BALTIMORE, MD 3,405,2903.4m $363.1m $363.1m 0.04% Added +312.5k +312,483
17 NORGES BANK 0.04% of their portfolio OSLO, Q8 3,377,6413.4m $360.1m $360.1m 0.04% Not comparable
18 Jupiter Topco LLC 0.11% of their portfolio NEW YORK, NY 2,605,1812.6m $277.8m $277.8m 0.11% First filing
19 UBS Group AG 0.04% of their portfolio ZURICH, V8 2,584,4462.6m $275.6m $275.6m 0.04% Added +847.0k +846,965
20 CITADEL ADVISORS LLC 0.16% of their portfolio MIAMI, FL 2,556,9732.6m $272.6m $272.6m 0.16% Added +374.4k +374,402
21 FRANKLIN RESOURCES INC 0.05% of their portfolio San Mateo, CA 2,273,2222.3m $242.4m $242.4m 0.05% Reduced -344.0k -344,029
22 MAVERICK CAPITAL LTD 2.07% of their portfolio DALLAS, TX 2,150,7622.2m $229.3m $229.3m 2.07% New
23 MILLENNIUM MANAGEMENT LLC 0.15% of their portfolio NEW YORK, NY 2,048,0052.0m $218.4m $218.4m 0.15% Added +890.2k +890,219
24 Qube Research & Technologies Ltd 0.20% of their portfolio LONDON, X0 1,682,3341.7m $179.4m $179.4m 0.20% Added +1.5m +1,533,819
25 WESTFIELD CAPITAL MANAGEMENT CO LP 0.57% of their portfolio BOSTON, MA 1,629,5611.6m $173.7m $173.7m 0.57% Added +161.1k +161,102
26 T. Rowe Price Investment Management, Inc. 0.11% of their portfolio BALTIMORE, MD 1,622,6751.6m $173.0m $173.0m 0.11% New
27 Integral Health Asset Management, LLC 7.00% of their portfolio New York, NY 1,600,0001.6m $170.6m $170.6m 7.00% Added +100.0k +100,000
28 Duquesne Family Office LLC 3.49% of their portfolio New York, NY 1,424,6901.4m $151.9m $151.9m 3.49% Added +270.6k +270,600
29 GOLDMAN SACHS GROUP INC 0.02% of their portfolio NEW YORK, NY 1,409,8851.4m $150.3m $150.3m 0.02% Added +467.2k +467,239
30 VANGUARD FIDUCIARY TRUST CO 0.03% of their portfolio MALVERN, PA 1,401,5521.4m $149.4m $149.4m 0.03% Added +47.0k +47,036
31 Bellevue Group AG 3.13% of their portfolio ZURICH, V8 1,393,4181.4m $148.6m $148.6m 3.13% Added +1.4m +1,383,384
32 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.03% of their portfolio NEW YORK, NY 1,335,0711.3m $142.3m $142.3m 0.03% Added +120.0k +120,046
33 Balyasny Asset Management L.P. 0.26% of their portfolio Chicago, IL 1,326,4301.3m $141.4m $141.4m 0.26% Added +1.1m +1,104,723
34 Paradigm Biocapital Advisors LP 2.65% of their portfolio NEW YORK, NY 1,325,9771.3m $141.4m $141.4m 2.65% Added +71.5k +71,489
35 NORTHERN TRUST CORP 0.02% of their portfolio CHICAGO, IL 1,315,3251.3m $140.2m $140.2m 0.02% Added +21.3k +21,325
36 Bank of New York Mellon Corp 0.02% of their portfolio NEW YORK, NY 1,312,7561.3m $140.0m $140.0m 0.02% Added +50.0k +50,007
37 TWO SIGMA INVESTMENTS, LP 0.10% of their portfolio NEW YORK, NY 1,242,2221.2m $132.4m $132.4m 0.10% Added +1.0m +1,005,205
38 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 1,233,4981.2m $131.5m $131.5m 0.01% Reduced -98.0k -98,044
39 Pictet Asset Management Holding SA 0.12% of their portfolio CAROUGE, V8 1,220,3531.2m $129.8m $129.8m 0.12% Added +118.1k +118,105
40 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio SAN FRANCISCO, CA 1,213,9631.2m $129.4m $129.4m 0.02% Added +144.6k +144,573
41 Hood River Capital Management LLC 0.82% of their portfolio PALM BEACH GARDENS, FL 1,056,8711.1m $112.7m $112.7m 0.82% Added +368.3k +368,317
42 BANK OF AMERICA CORP /DE/ 0.01% of their portfolio CHARLOTTE, NC 1,023,1141.0m $109.1m $109.1m 0.01% Reduced -479.2k -479,167
43 SEI INVESTMENTS CO 0.10% of their portfolio OAKS, PA 1,015,8701.0m $108.3m $108.3m 0.10% Reduced -379.9k -379,924
44 NWI MANAGEMENT LP 6.91% of their portfolio NEW YORK, NY 1,014,0001.0m $108.1m $108.1m 6.91% Reduced -1.0m -1,014,000
45 Castle Hook Partners LP 1.13% of their portfolio NEW YORK, NY 993,310993.3k $105.9m $105.9m 1.13% Reduced -276.4k -276,444
46 JENNISON ASSOCIATES LLC 0.06% of their portfolio NEW YORK, NY 905,094905.1k $96.5m $96.5m 0.06% Added +300.4k +300,400
47 Polar Capital Holdings Plc 0.27% of their portfolio London, X0 890,872890.9k $95.0m $95.0m 0.27% Added +522.8k +522,765
48 FIL Ltd 0.07% of their portfolio HAMILTON, D0 856,214856.2k $91.3m $91.3m 0.07% Added +27.3k +27,267
49 PRINCIPAL FINANCIAL GROUP INC 0.04% of their portfolio DES MOINES, IA 856,126856.1k $91.3m $91.3m 0.04% Reduced -60.3k -60,338
50 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.13% of their portfolio Boston, MA 850,000850.0k $90.6m $90.6m 0.13% Reduced -50.0k -50,000
51 Fiera Capital Corp 0.33% of their portfolio MONTREAL, A8 843,042843.0k $89.9m $89.9m 0.33% Reduced -178.9k -178,928
52 Legal & General Group Plc 0.02% of their portfolio London, X0 826,431826.4k $88.1m $88.1m 0.02% Added +39.4k +39,352
53 FRONTIER CAPITAL MANAGEMENT CO LLC 0.79% of their portfolio Boston, MA 795,242795.2k $84.8m $84.8m 0.79% Added +325.7k +325,681
54 AMERICAN CENTURY COMPANIES INC 0.04% of their portfolio KANSAS CITY, MO 759,735759.7k $81.0m $81.0m 0.04% Reduced -166.1k -166,064
55 SAMLYN CAPITAL, LLC 1.29% of their portfolio New York, NY 732,568732.6k $78.1m $78.1m 1.29% Added +315.4k +315,363
56 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.07% of their portfolio BALA CYNWYD, PA 729,354729.4k $77.8m $77.8m 0.07% Added +555.7k +555,724
57 TimesSquare Capital Management, LLC 1.14% of their portfolio NEW YORK, NY 728,096728.1k $77.6m $77.6m 1.14% Added +143.3k +143,298
58 Clearbridge Investments, LLC 0.06% of their portfolio NEW YORK, NY 715,922715.9k $76.3m $76.3m 0.06% Added +72.5k +72,487
59 Ensign Peak Advisors, Inc 0.12% of their portfolio SALT LAKE CITY, UT 702,951703.0k $74.9m $74.9m 0.12% Added +203.2k +203,195
60 DEUTSCHE BANK AG\ 0.02% of their portfolio FRANKFURT AM MAIN, 2M 690,590690.6k $73.6m $73.6m 0.02% Added +128.1k +128,116
61 HRT FINANCIAL LP 0.17% of their portfolio NEW YORK, NY 689,981690.0k $73.6m $73.6m 0.17% New
62 RAYMOND JAMES FINANCIAL INC 0.02% of their portfolio ST. PETERSBURG, FL 660,601660.6k $70.4m $70.4m 0.02% Reduced -114.5k -114,547
63 Affinity Asset Advisors, LLC 3.39% of their portfolio NEW YORK, NY 650,000650.0k $69.3m $69.3m 3.39% Added +170.0k +170,000
64 WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.20% of their portfolio CHICAGO, IL 629,831629.8k $67.2m $67.2m 0.20% Reduced -272.8k -272,835
65 GW&K Investment Management, LLC 0.52% of their portfolio BOSTON, MA 629,760629.8k $67.1m $67.1m 0.52% Added +6.7k +6,712
66 Squarepoint Ops LLC 0.13% of their portfolio NEW YORK, NY 616,464616.5k $65.7m $65.7m 0.13% Added +577.1k +577,148
67 AQR CAPITAL MANAGEMENT LLC 0.02% of their portfolio Greenwich, CT 612,832612.8k $65.3m $65.3m 0.02% Reduced -62.7k -62,653
68 Railway Pension Investments Ltd 0.81% of their portfolio LONDON, X0 604,700604.7k $64.5m $64.5m 0.81% New
69 Swiss National Bank 0.03% of their portfolio ZURICH, V8 593,512593.5k $63.3m $63.3m 0.03% Reduced -32.4k -32,400
70 Nuveen, LLC 0.02% of their portfolio CHARLOTTE, NC 591,844591.8k $63.1m $63.1m 0.02% Added +57.1k +57,094
71 Artia Global Partners LP 11.94% of their portfolio MIAMI, FL 589,052589.1k $62.8m $62.8m 11.94% Reduced -39.7k -39,660
72 EVENTIDE ASSET MANAGEMENT, LLC 0.83% of their portfolio Boston, MA 583,665583.7k $62.2m $62.2m 0.83% Added +37.4k +37,355
73 Aberdeen Group plc 0.09% of their portfolio EDINBURGH, X0 577,437577.4k $61.6m $61.6m 0.09% Added +300.4k +300,421
74 Davern Capital Partners, LP 10.18% of their portfolio NY, NY 559,824559.8k $59.7m $59.7m 10.18% Added +377.3k +377,262
75 Candriam S.C.A. 0.27% of their portfolio STRASSEN, N4 555,131555.1k $59.1m $59.1m 0.27% Added +153.4k +153,396
76 WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio Boston, MA 543,893543.9k $58.0m $58.0m 0.01% Added +144.8k +144,849
77 Point72 Asset Management, L.P. 0.09% of their portfolio STAMFORD, CT 536,997537.0k $57.3m $57.3m 0.09% New
78 Long Focus Capital Management, LLC 2.30% of their portfolio SAN JUAN, PR 528,000528.0k $56.3m $56.3m 2.30% Added +383.0k +383,000
79 MARSHALL WACE, LLP 0.05% of their portfolio LONDON, X0 501,930501.9k $53.5m $53.5m 0.05% Added +189.4k +189,365
80 Amundi 0.01% of their portfolio Paris, I0 487,525487.5k $52.0m $52.0m 0.01% Reduced -317.5k -317,452
81 BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.05% of their portfolio Paris, I0 475,307475.3k $50.7m $50.7m 0.05% Added +7.6k +7,554
82 ALLIANCEBERNSTEIN L.P. 0.03% of their portfolio NASHVILLE, TN 462,796462.8k $75.7m $75.7m 0.03% Reduced -225.9k -225,938
83 Bridgewater Associates, LP 0.20% of their portfolio Westport, CT 455,392455.4k $48.6m $48.6m 0.20% Added +159.8k +159,813
84 Sumitomo Mitsui Trust Group, Inc. 0.03% of their portfolio CHIYODA-KU, TOKYO, M0 437,713437.7k $46.7m $46.7m 0.03% Reduced -63.6k -63,569
85 Assenagon Asset Management S.A. 0.03% of their portfolio SENNINGERBERG, N4 436,540436.5k $46.5m $46.5m 0.03% Added +373.3k +373,281
86 ROYAL BANK OF CANADA 0.01% of their portfolio TORONTO, A6 416,487416.5k $44.4m $44.4m 0.01% Reduced -106.6k -106,614
87 VANGUARD ASSET MANAGEMENT, Ltd 0.03% of their portfolio London, EC4N 8AF, X0 416,108416.1k $44.4m $44.4m 0.03% Added +56.0k +56,033
88 Palo Alto Investors LP 6.10% of their portfolio PALO ALTO, CA 413,980414.0k $44.1m $44.1m 6.10% Reduced -1.3k -1,289
89 DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio AUSTIN, TX 408,388408.4k $43.5m $43.5m 0.01% Added +7.5k +7,488
90 BNP PARIBAS FINANCIAL MARKETS 0.02% of their portfolio PARIS, I0 400,765400.8k $42.7m $42.7m 0.02% Reduced -203.8k -203,835
91 Eagle Health Investments LP 6.79% of their portfolio Greenwich, CT 384,130384.1k $41.0m $41.0m 6.79% Added +159.9k +159,859
92 NEUBERGER BERMAN GROUP LLC 0.03% of their portfolio NEW YORK, NY 378,816378.8k $40.4m $40.4m 0.03% Added +108.1k +108,116
93 Prosight Management, LP 6.90% of their portfolio DALLAS, TX 375,609375.6k $40.0m $40.0m 6.90% New
94 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 368,261368.3k $39.3m $39.3m 0.00% Reduced -6.1m -6,144,628
95 GATEWAY INVESTMENT ADVISERS LLC 0.38% of their portfolio CINCINNATI, OH 365,000365.0k $38.9m $38.9m 0.38% Unchanged
96 Rock Springs Capital Management LP 1.88% of their portfolio Baltimore, MD 362,150362.1k $38.6m $38.6m 1.88% Added +47.9k +47,850
97 ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio Berwyn, PA 336,997337.0k $35.9m $35.9m 0.01% Added +37.1k +37,072
98 VICTORY CAPITAL MANAGEMENT INC 0.02% of their portfolio San Antonio, TX 306,651306.7k $32.7m $32.7m 0.02% Reduced -89.6k -89,594
99 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.03% of their portfolio WEST SACRAMENTO, CA 304,798304.8k $32.5m $32.5m 0.03% Added +1.6k +1,616
100 NEW YORK STATE COMMON RETIREMENT FUND 0.04% of their portfolio ALBANY, NY 304,236304.2k $32.4m $32.4m 0.04% Added +10.7k +10,690