SAB BIOTHERAPEUTICS INC SABS
COM NEW · Common Stock · CUSIP 78397T202
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersMiami Beach, FL
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($408.9k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $3.90. Options: 5 managers hold calls ($760.1k notional), 2 hold puts ($923.1k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q4 2023 | 3 |
| Q1 2024 | 25 |
| Q2 2024 | 23 |
| Q3 2024 | 26 |
| Q4 2024 | 26 |
| Q1 2025 | 27 |
| Q2 2025 | 26 |
| Q3 2025 | 34 |
| Q4 2025 | 48 |
| Q1 2026 | 76 |
| Q2 2026 | 87 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 7 | 6 |
| Q4 2024 | 9 | 11 |
| Q1 2025 | 10 | 10 |
| Q2 2025 | 9 | 8 |
| Q3 2025 | 22 | 6 |
| Q4 2025 | 30 | 11 |
| Q1 2026 | 55 | 11 |
| Q2 2026 | 56 | 36 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $0 | $0 | — |
| Q4 2025 | $0 | $0 | — |
| Q1 2026 | $611.3k | $283.0k | 0.46 |
| Q2 2026 | $760.1k | $923.1k | 1.21 |
Biggest buyers
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Added | +3.0m |
| BlackRock, Inc. | Added | +2.8m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +975.1k |
| Affinity Asset Advisors, LLC | Added | +950.0k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +479.2k |
| STATE STREET CORP | Added | +456.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | +438.5k |
| UBS Group AG | Added | +319.3k |
| Polymer Capital Management (HK) LTD | New | +306.6k |
| NORTHERN TRUST CORP | Added | +305.1k |
Biggest sellers
| Vivo Capital, LLC | Reduced | -4.1m |
| Woodline Partners LP | Reduced | -1.7m |
| Commodore Capital LP | Reduced | -1.5m |
| Jefferies Financial Group Inc. | Sold out | -903.1k |
| AMERIPRISE FINANCIAL INC | Reduced | -865.1k |
| ExodusPoint Capital Management, LP | Sold out | -768.6k |
| Monashee Investment Management LLC | Sold out | -500.0k |
| MARSHALL WACE, LLP | Sold out | -463.9k |
| STEMPOINT CAPITAL LP | Reduced | -407.4k |
| DV Trading LLC | Sold out | -400.0k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $315.9k81.0k shares |
| JANE STREET GROUP, LLC | Reduced | $209.0k53.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $110.8k28.4k shares |
| GROUP ONE TRADING LLC | Added | $78.8k20.2k shares |
| SIMPLEX TRADING, LLC | Added | $45.6k11.7k shares |
Biggest puts
| JANE STREET GROUP, LLC | Added | $883.4k226.5k shares |
| SIMPLEX TRADING, LLC | Reduced | $39.8k10.2k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Vivo Opportunity Fund Holdings, L.P. 13G · passive investor no change · filed 2026-08-14 | 10.0% |
| Commodore Capital LP 13G · passive investor no change · filed 2026-08-14 | 9.9% |
| RA CAPITAL MANAGEMENT, L.P. 13D · may seek influence no change · filed 2026-08-10 | 9.9% |
| BALYASNY ASSET MANAGEMENT L.P. 13G · institution -0.5 pts · filed 2026-08-14 | 9.4% |
| BIOTECHNOLOGY VALUE FUND L P 13G · passive investor -0.9 pts · filed 2026-02-17 | 9.1% |
| Caligan Partners LP 13G · institution -1.6 pts · filed 2026-08-14 | 8.8% |
| Adage Capital Management, L.P. 13G · institution new · filed 2026-08-12 | 8.4% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor -1.1 pts · filed 2026-08-14 | 7.3% |
| Woodline Partners LP 13G · institution -3.1 pts · filed 2026-08-14 | 6.8% |
| MILLENNIUM MANAGEMENT LLC 13G · passive investor new · filed 2026-05-01 | 5.1% |
Fell to 5% or below in the last year: RTW INVESTMENTS, LP (3.2%, 2026-02-17)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported since 1 Apr 2026.
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Caligan Partners LP 1.50% of their portfolio | 8.0m $31.1m | Unchanged |
| Vivo Capital, LLC 2.60% of their portfolio | 7.3m $28.5m | Reduced -4.1m |
| PERCEPTIVE ADVISORS LLC 0.40% of their portfolio | 6.6m $25.8m | Added +195.8k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.04% of their portfolio | 6.4m $25.0m | Added +3.0m |
| RA CAPITAL MANAGEMENT, L.P. 0.15% of their portfolio | 4.4m $17.2m | Unchanged |
| Balyasny Asset Management L.P. 0.03% of their portfolio | 3.8m $14.7m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 3.1m $12.0m | Added +2.8m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 3.0m $11.6m | Added +479.2k |
| Commodore Capital LP 0.67% of their portfolio | 2.9m $11.2m | Reduced -1.5m |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 2.7m $10.7m | Reduced -283.6k |
| Spruce Street Capital LP 1.68% of their portfolio | 2.2m $8.6m | Unchanged |
| Sessa Capital IM, L.P. 0.15% of their portfolio | 2.2m $8.6m | Unchanged |
| Affinity Asset Advisors, LLC 0.29% of their portfolio | 1.5m $5.9m | Added +950.0k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.11% of their portfolio | 1.5m $5.8m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $5.0m | Added +975.1k |
| Woodline Partners LP 0.01% of their portfolio | 1.2m $4.6m | Reduced -1.7m |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 1.2m $4.6m | Reduced -203.0k |
| Propel Bio Management, LLC 2.20% of their portfolio | 1.1m $4.2m | Added +63.8k |
| Soleus Capital Management, L.P. 0.12% of their portfolio | 900.0k $3.5m | Reduced -150.0k |
| Seven Fleet Capital Management LP 0.47% of their portfolio | 736.1k $2.9m | Added +236.1k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 611.0k $2.4m | Reduced -865.1k |
| STATE STREET CORP 0.00% of their portfolio | 530.8k $2.1m | Added +456.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 438.5k $1.7m | New |
| DV EQUITIES, LLC 0.23% of their portfolio | 400.0k $1.6m | First filing |
| AWM Investment Company, Inc. 0.13% of their portfolio | 375.0k $1.5m | Reduced -25.0k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 374.0k $1.5m | Added +176.4k |
| UBS Group AG 0.00% of their portfolio | 365.9k $1.4m | Added +319.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 362.5k $1.4m | Added +305.1k |
| STEMPOINT CAPITAL LP 0.23% of their portfolio | 342.6k $1.3m | Reduced -407.4k |
| HB Wealth Management, LLC 0.01% of their portfolio | 307.5k $1.2m | Unchanged |
| Polymer Capital Management (HK) LTD 0.12% of their portfolio | 306.6k $1.2m | New |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 292.7k $1.1m | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 214.6k $837.1k | Added +33.4k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 191.3k $746.1k | Added +77.4k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 107.8k $420.6k | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 105.7k $412.2k | New |
| Simplify Asset Management Inc. 0.01% of their portfolio | 104.8k $408.9k | Reduced -82.4k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 84.7k $330.3k | Added +47.2k |
| ALPS ADVISORS INC 0.00% of their portfolio | 77.6k $302.6k | New |
| Stonepine Capital Management, LLC 0.22% of their portfolio | 73.3k $285.8k | Added +23.3k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 62.8k $244.9k | New |
| Nuveen, LLC 0.00% of their portfolio | 58.4k $227.8k | New |
| Pathstone Holdings, LLC 0.00% of their portfolio | 50.6k $197.5k | Unchanged |
| Kestra Advisory Services, LLC 0.00% of their portfolio | 49.8k $194.3k | Reduced -11.9k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 45.2k $176.1k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 44.1k $171.9k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 42.4k $165.2k | New |
| IFP Advisors, Inc 0.00% of their portfolio | 38.7k $150.9k | New |
| BARCLAYS PLC 0.00% of their portfolio | 35.9k $140.0k | Added +35.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 35.6k $139.0k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 28.0k $109.3k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 27.0k $105.2k | New |
| CITIGROUP INC 0.00% of their portfolio | 26.6k $103.7k | Reduced -10.2k |
| Persistent Asset Partners Ltd 0.03% of their portfolio | 25.4k $99.1k | Reduced -44.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 25.1k $98.0k | Reduced -30.6k |
| Invesco Ltd. 0.00% of their portfolio | 22.6k $88.1k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 20.0k $78.0k | New |
| First PREMIER Bank 0.01% of their portfolio | 19.0k $74.0k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 18.1k $70.5k | Added +18.0k |
| Scientech Research LLC 0.06% of their portfolio | 17.4k $68.0k | Added +6.6k |
| Quadrature Capital Ltd 0.00% of their portfolio | 15.2k $59.3k | Reduced -20.1k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 14.6k $57.1k | New |
| MORGAN STANLEY 0.00% of their portfolio | 13.8k $53.6k | Added +1.8k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 12.9k $50.5k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 12.9k $50.3k | New |
| Miller Capital Partners, Inc. 0.02% of their portfolio | 12.9k $50.2k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 12.8k $49.9k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 11.9k $46.2k | Unchanged |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 10.3k $40.1k | Added +2.6k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 8.6k $33.7k | Added +7.7k |
| STRS OHIO 0.00% of their portfolio | 8.5k $33.1k | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 8.1k $31.5k | Added +311 |
| Plante Moran Financial Advisors, LLC 0.00% of their portfolio | 5.9k $23.1k | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 4.2k $16.5k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.9k $15.4k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 3.5k $13.5k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 2.5k $9.8k | Reduced -749 |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 2.0k $7.8k | New |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 1.9k $7.2k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 1.7k $7.0k | Added +1.7k |
| Truvestments Capital LLC 0.00% of their portfolio | 1.1k $4.3k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 875 $3.4k | New |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 742 $2.9k | Added +581 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 598 $2.3k | New |
| GS Investments, Inc. 0.00% of their portfolio | 200 $780 | Unchanged |
| FMR LLC 0.00% of their portfolio | 116 $452 | New |
| HARBOUR INVESTMENTS, INC. 0.00% of their portfolio | 50 $195 | Unchanged |