Vault-13

ENGENE THERAPEUTICS INC ENGN

COM · Common Stock · CUSIP 29286X101

56 institutional holders +54 vs Q1 2026
38,491,61838.5m shares reported held*
57.5% of all shares outstanding*
$66.6mreported value*
55 new 0 added 0 reduced 1 sold out net bought ≈ $66.0m (+38.1m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 67.0m as of 2026-06-09, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.73. Options: 5 managers hold calls ($246.2k notional), 4 hold puts ($769.7k).

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

0204060Q1 26: 2Q2 26: 5656Q1 26Q2 26
Numbers
QuarterHolders
Q1 20262
Q2 202656

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$200k$400k$600k$800kQ3 25 calls: $0Q3 25 puts: $0Q3 25P/C —Q4 25 calls: $0Q4 25 puts: $0Q4 25P/C —Q1 26 calls: $0Q1 26 puts: $0Q1 26P/C —Q2 26 calls: $246.2kQ2 26 puts: $769.7kQ2 26P/C 3.13
Numbers
QuarterCallsPutsP/C
Q3 2025$0$0—
Q4 2025$0$0—
Q1 2026$0$0—
Q2 2026$246.2k$769.7k3.13

Biggest buyers

BML Capital Management, LLC New +6,669,908+6.7m
Siren, L.L.C. New +6,256,662+6.3m
PERCEPTIVE ADVISORS LLC New +4,822,169+4.8m
AMERIPRISE FINANCIAL INC New +2,675,876+2.7m
Nextech Invest Ltd. New +2,324,943+2.3m
ADAR1 Capital Management, LLC New +2,104,986+2.1m
Vestal Point Capital, LP New +1,667,430+1.7m
ACORN CAPITAL ADVISORS, LLC New +1,271,257+1.3m
Peapod Lane Capital LLC New +1,102,149+1.1m
Balyasny Asset Management L.P. New +1,007,344+1.0m

Biggest sellers

MARSHALL WACE, LLP Sold out -343,928-343.9k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP New $107.1k61.9k shares
CITADEL ADVISORS LLC New $53.3k30.8k shares
JANE STREET GROUP, LLC New $32.9k19.0k shares
GROUP ONE TRADING LLC New $28.5k16.5k shares
SIMPLEX TRADING, LLC New $24.4k14.1k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP New $541.7k313.1k shares
JANE STREET GROUP, LLC New $94.8k54.8k shares
SIMPLEX TRADING, LLC New $76.5k44.2k shares
CITADEL ADVISORS LLC New $56.7k32.8k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Invus Global Management, LLC 13G · passive investor +1.5 pts · filed 2026-08-13 9.3% +1.5 pts 6.3m≈ $10.8m 2026-08-13

Fell to 5% or below in the last year: Deep Track Capital, LP (0.0%, 2026-08-14), Blue Owl Capital Holdings LP (0.8%, 2026-08-12)

Insider purchases and sales since 1 Apr 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
101Q4 24: 0 buyingQ4 24: 0 sellingQ1 25: 0 buyingQ1 25: 0 sellingQ1 25Q2 25: 0 buyingQ2 25: 0 sellingQ3 25: 0 buyingQ3 25: 0 sellingQ3 25Q4 25: 0 buyingQ4 25: 0 sellingQ1 26: 0 buyingQ1 26: 0 sellingQ1 26Q2 26: 0 buyingQ2 26: 0 sellingQ3 26: 1 buyingQ3 26: 0 sellingQ3 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20240—0——
Q1 20250—0——
Q2 20250—0——
Q3 20250—0——
Q4 20250—0——
Q1 20260—0——
Q2 20260—0——
Q3 20261$10.1k0——
DateInsiderTradeSharesPrice ValueTheir holding
2026-09-22 Grossman William Interim Chief Medical Officer, director Bought 5,102 $1.97 $10.1k5.1k shares new

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 BML Capital Management, LLC 6.59% of their portfolio ZIONSVILLE, IN 6,669,9086.7m $11.5m $11.5m 6.59% New
2 Siren, L.L.C. 0.22% of their portfolio New York, NY 6,256,6626.3m $10.8m $10.8m 0.22% New
3 PERCEPTIVE ADVISORS LLC 0.13% of their portfolio NEW YORK, NY 4,822,1694.8m $8.3m $8.3m 0.13% New
4 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 2,675,8762.7m $4.6m $4.6m 0.00% New
5 Nextech Invest Ltd. 0.19% of their portfolio Zurich, V8 2,324,9432.3m $4.0m $4.0m 0.19% New
6 ADAR1 Capital Management, LLC 0.17% of their portfolio AUSTIN, TX 2,104,9862.1m $3.6m $3.6m 0.17% New
7 Vestal Point Capital, LP 0.07% of their portfolio NEW YORK, NY 1,667,4301.7m $2.9m $2.9m 0.07% New
8 ACORN CAPITAL ADVISORS, LLC 0.60% of their portfolio NEW YORK, NY 1,271,2571.3m $2.2m $2.2m 0.60% New
9 Peapod Lane Capital LLC 1.29% of their portfolio Bedford Hills, NY 1,102,1491.1m $1.9m $1.9m 1.29% New
10 Balyasny Asset Management L.P. 0.00% of their portfolio Chicago, IL 1,007,3441.0m $1.7m $1.7m 0.00% New
11 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 966,627966.6k $1.7m $1.7m 0.00% New
12 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 829,700829.7k $1.4m $1.4m 0.00% New
13 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 717,686717.7k $1.2m $1.2m 0.00% New
14 Affinity Asset Advisors, LLC 0.05% of their portfolio NEW YORK, NY 600,000600.0k $1.0m $1.0m 0.05% New
15 UBS Group AG 0.00% of their portfolio ZURICH, V8 509,087509.1k $880.7k $880.7k 0.00% New
16 Eversept Partners, LP 0.04% of their portfolio NEW YORK, NY 469,584469.6k $812.4k $812.4k 0.04% New
17 Kynam Capital Management, LP 0.04% of their portfolio PRINCETON, NJ 457,855457.9k $792.1k $792.1k 0.04% New
18 Seven Fleet Capital Management LP 0.12% of their portfolio MOUNTAIN VIEW, CA 411,065411.1k $711.1k $711.1k 0.12% New
19 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 382,459382.5k $661.7k $661.7k 0.00% New
20 Rangeley Capital, LLC 0.49% of their portfolio NEW CANAAN, CT 305,102305.1k $527.8k $527.8k 0.49% New
21 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 282,515282.5k $488.8k $488.8k 0.00% New
22 KENNEDY CAPITAL MANAGEMENT LLC 0.01% of their portfolio ST LOUIS, MO 268,735268.7k $464.9k $464.9k 0.01% New
23 Woodline Partners LP 0.00% of their portfolio San Francisco, CA 250,000250.0k $432.5k $432.5k 0.00% New
24 Quadrature Capital Ltd 0.00% of their portfolio LONDON, X0 239,035239.0k $413.5k $413.5k 0.00% New
25 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 215,381215.4k $372.6k $372.6k 0.00% New
26 Elmind Capital, LP 0.09% of their portfolio NEW YORK, NY 210,000210.0k $363.3k $363.3k 0.09% New
27 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 200,187200.2k $346.3k $346.3k 0.00% New
28 Privium Fund Management B.V. 0.05% of their portfolio AMSTERDAM, P7 170,000170.0k $294.1k $294.1k 0.05% New
29 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 164,570164.6k $284.7k $284.7k 0.00% New
30 XTX Topco Ltd 0.00% of their portfolio LONDON, X0 151,424151.4k $262.0k $262.0k 0.00% New
31 Marquette Asset Management, LLC 0.03% of their portfolio MINNEAPOLIS, MN 150,546150.5k $260.4k $260.4k 0.03% New
32 Persistent Asset Partners Ltd 0.06% of their portfolio HONG KONG, K3 114,493114.5k $198.1k $198.1k 0.06% New
33 DAFNA Capital Management LLC 0.02% of their portfolio LOS ANGELES, CA 74,65074.7k $129.1k $129.1k 0.02% New
34 Jain Global LLC 0.00% of their portfolio NEW YORK, NY 43,23143.2k $74.8k $74.8k 0.00% New
35 Scientech Research LLC 0.06% of their portfolio JERSEY CITY, NJ 40,71040.7k $70.4k $70.4k 0.06% New
36 Verdad Advisers, LP 0.07% of their portfolio BOSTON, MA 39,30039.3k $68.0k $68.0k 0.07% New
37 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 38,29138.3k $66.2k $66.2k 0.00% New
38 GSA CAPITAL PARTNERS LLP 0.00% of their portfolio LONDON, X0 37,34637.3k $65.0k $65.0k 0.00% New
39 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 33,08633.1k $57.2k $57.2k 0.00% New
40 Engineers Gate Manager LP 0.00% of their portfolio NEW YORK, NY 27,28627.3k $47.2k $47.2k 0.00% New
41 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 25,41925.4k $44.0k $44.0k 0.00% New
42 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 24,47024.5k $42.3k $42.3k 0.00% New
43 SECTORAL ASSET MANAGEMENT INC 0.03% of their portfolio MONTREAL, A8 21,70021.7k $37.5k $37.5k 0.03% New
44 RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio ST. PETERSBURG, FL 21,35621.4k $36.9k $36.9k 0.00% New
45 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 18,50418.5k $32.0k $32.0k 0.00% New
46 HRT FINANCIAL LP 0.00% of their portfolio NEW YORK, NY 16,83116.8k $29.0k $29.0k 0.00% New
47 Point72 Asset Management, L.P. 0.00% of their portfolio STAMFORD, CT 13,99214.0k $24.2k $24.2k 0.00% New
48 Virtu Financial LLC 0.00% of their portfolio New York, NY 13,98614.0k $24.0k $24.0k 0.00% New
49 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 11,32511.3k $20.0k $20.0k 0.00% New
50 PFS Partners, LLC 0.01% of their portfolio MINE HILL, NJ 11,00011.0k $19.0k $19.0k 0.01% New
51 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 6,8406.8k $11.8k $11.8k 0.00% New
52 WOLVERINE ASSET MANAGEMENT LLC 0.00% of their portfolio CHICAGO, IL 2,9643.0k $5.1k $5.1k 0.00% New
53 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 399399 $690 $690 0.00% New
54 Farther Finance Advisors, LLC 0.00% of their portfolio SAN FRANCISCO, CA 100100 $173 $173 0.00% New
55 Aquatic Capital Management LLC 0.00% of their portfolio CHICAGO, IL 2929 $50 $50 0.00% New
56 SBI Securities Co., Ltd. 0.00% of their portfolio TOKYO, M0 2828 $48 $48 0.00% Unchanged