Vault-13

ARROWHEAD PHARMACEUTICALS IN ARWR

COM · Common Stock · CUSIP 04280A100 · ISIN US04280A1007

Biopharmaceutical company

500 institutional holders +62 vs Q1 2026
119,363,733119.4m shares reported held*
84.5% of all shares outstanding*
$9.7bnreported value*
118 new 153 added 156 reduced 58 sold out net sold ≈ $424.4m (-5.2m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($12.7m this quarter). Holder counts are more reliable. Shares outstanding: 141.3m as of 2026-07-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $81.55. Options: 16 managers hold calls ($157.9m notional), 14 hold puts ($66.2m).

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

0200400600Q3 22: 278Q4 22: 283Q1 23: 257Q2 23: 274Q3 23: 258Q4 23: 267Q1 24: 276Q2 24: 274Q3 24: 273Q4 24: 271Q1 25: 266Q2 25: 282Q3 25: 303Q4 25: 402Q1 26: 438Q2 26: 500500Q3 22Q3 23Q3 24Q3 25Q2 26
Numbers
QuarterHolders
Q3 2022278
Q4 2022283
Q1 2023257
Q2 2023274
Q3 2023258
Q4 2023267
Q1 2024276
Q2 2024274
Q3 2024273
Q4 2024271
Q1 2025266
Q2 2025282
Q3 2025303
Q4 2025402
Q1 2026438
Q2 2026500

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
4000400Q3 24: 121 bought or addedQ3 24: 123 cut or sold outQ4 24: 122 bought or addedQ4 24: 127 cut or sold outQ4 24Q1 25: 130 bought or addedQ1 25: 126 cut or sold outQ2 25: 151 bought or addedQ2 25: 120 cut or sold outQ2 25Q3 25: 165 bought or addedQ3 25: 121 cut or sold outQ4 25: 234 bought or addedQ4 25: 137 cut or sold outQ4 25Q1 26: 264 bought or addedQ1 26: 171 cut or sold outQ2 26: 271 bought or addedQ2 26: 214 cut or sold outQ2 26
Numbers
QuarterBought or addedCut or sold out
Q3 2024121123
Q4 2024122127
Q1 2025130126
Q2 2025151120
Q3 2025165121
Q4 2025234137
Q1 2026264171
Q2 2026271214

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$50m$100m$150m$200mQ3 25 calls: $39.1mQ3 25 puts: $9.8mQ3 25P/C 0.25Q4 25 calls: $156.8mQ4 25 puts: $38.8mQ4 25P/C 0.25Q1 26 calls: $106.3mQ1 26 puts: $55.8mQ1 26P/C 0.53Q2 26 calls: $157.9mQ2 26 puts: $66.2mQ2 26P/C 0.42
Numbers
QuarterCallsPutsP/C
Q3 2025$39.1m$9.8m0.25
Q4 2025$156.8m$38.8m0.25
Q1 2026$106.3m$55.8m0.53
Q2 2026$157.9m$66.2m0.42

Biggest buyers

FIRST TRUST ADVISORS LP Added +1,203,770+1.2m
Holocene Advisors, LP New +1,106,177+1.1m
FMR LLC Added +773,152+773.2k
Avoro Capital Advisors LLC Added +655,556+655.6k
Invesco Ltd. Added +603,329+603.3k
DIMENSIONAL FUND ADVISORS LP Added +573,077+573.1k
TWO SIGMA INVESTMENTS, LP Added +544,809+544.8k
1832 Asset Management L.P. New +538,500+538.5k
HRT FINANCIAL LP New +498,655+498.7k
Assenagon Asset Management S.A. Added +345,119+345.1k

Biggest sellers

BlackRock, Inc. Reduced -3,330,966-3.3m
STATE STREET CORP Reduced -801,490-801.5k
VANGUARD PORTFOLIO MANAGEMENT LLC Reduced -794,781-794.8k
D. E. Shaw & Co., Inc. Reduced -752,278-752.3k
GEODE CAPITAL MANAGEMENT, LLC Reduced -748,216-748.2k
Vestal Point Capital, LP Reduced -700,000-700.0k
Pictet Asset Management Holding SA Reduced -699,847-699.8k
GOLDMAN SACHS GROUP INC Reduced -589,916-589.9k
RTW INVESTMENTS, LP Sold out -585,682-585.7k
RENAISSANCE TECHNOLOGIES LLC Reduced -567,574-567.6k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $70.7m867.6k shares
Caption Management, LLC Added $25.7m315.6k shares
CITADEL ADVISORS LLC Added $21.8m266.9k shares
JANE STREET GROUP, LLC Reduced $11.1m136.6k shares
MILLENNIUM MANAGEMENT LLC New $6.4m78.2k shares
GROUP ONE TRADING LLC Added $5.8m71.4k shares
IMC-Chicago, LLC New $5.7m70.2k shares
CITIGROUP INC Added $3.2m38.7k shares
SIMPLEX TRADING, LLC Added $2.5m31.2k shares
Point72 Asset Management, L.P. Reduced $2.0m24.5k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $34.6m424.5k shares
JANE STREET GROUP, LLC Reduced $8.2m100.2k shares
Ikarian Capital, LLC Added $8.2m100.0k shares
CITADEL ADVISORS LLC Reduced $4.8m59.1k shares
BOOTHBAY FUND MANAGEMENT, LLC Added $2.4m29.6k shares
CITIGROUP INC Added $2.2m26.7k shares
HRT FINANCIAL LP Added $1.5m18.9k shares
Point72 Asset Management, L.P. Added $1.3m15.4k shares
IMC-Chicago, LLC New $1.1m13.9k shares
SIMPLEX TRADING, LLC Reduced $1.0m12.3k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
BlackRock, Inc. 13G · institution -2.1 pts · filed 2026-07-27 10.1% -2.1 pts 14.2m≈ $1.2bn 2026-07-27
Avoro Capital Advisors LLC 13G · institution +1.3 pts · filed 2026-08-14 9.6% +1.3 pts 13.8m≈ $1.1bn 2026-08-14
FMR LLC 13G · institution new · filed 2026-05-06 5.2% new 7.3m≈ $599.0m 2026-05-06
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-29 5.0% new 7.1m≈ $577.2m 2026-04-29

Fell to 5% or below in the last year: VANGUARD PORTFOLIO MANAGEMENT LLC (4.5%, 2026-07-31; now reported by VANGUARD CAPITAL MANAGEMENT LLC), VANGUARD GROUP INC (0.0%, 2026-03-26; now reported by VANGUARD CAPITAL MANAGEMENT LLC)

Insider purchases and sales since 1 Apr 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
10010Q4 24: 0 buyingQ4 24: 5 sellingQ1 25: 0 buyingQ1 25: 5 sellingQ1 25Q2 25: 0 buyingQ2 25: 1 sellingQ3 25: 0 buyingQ3 25: 1 sellingQ3 25Q4 25: 0 buyingQ4 25: 7 sellingQ1 26: 0 buyingQ1 26: 3 sellingQ1 26Q2 26: 0 buyingQ2 26: 3 sellingQ3 26: 0 buyingQ3 26: 2 sellingQ3 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20240—5$1.4m$1.4m
Q1 20250—5$8.6m$7.8m
Q2 20250—1$1.5m—
Q3 20250—1$1.0m$1.0m
Q4 20250—7$27.8m$8.5m
Q1 20260—3$7.2m$7.2m
Q2 20260—3$1.9m$1.9m
Q3 20260—2$1.2m—
DateInsiderTradeSharesPrice ValueTheir holding
2026-08-18 PERRY MICHAEL S Director Sold 11,600 $87.30 $1.0m11.6k shares -9%
2026-08-18 OLUKOTUN ADEOYE Y Director Sold 2,000 $86.96 $173.9k2.0k shares -6%
2026-05-12 Lu Hongbo Director Sold plan 2,970 $76.88 $228.3k3.0k shares -5%
2026-04-23 Hamilton James C Chief Medical Officer Sold plan 10,000 $75.00 $750.0k10.0k shares -4%
2026-04-22 Apel Daniel Joseph Chief Financial Officer Sold plan 13,095 $71.35 $934.3k13.1k shares -7%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 BlackRock, Inc. 0.02% of their portfolio New York, NY 14,830,55314.8m $1.2bn $1.2bn 0.02% Reduced -3.3m -3,330,966
2 Avoro Capital Advisors LLC 8.31% of their portfolio NEW YORK, NY 11,355,55511.4m $925.6m $925.6m 8.31% Added +655.6k +655,556
3 FMR LLC 0.03% of their portfolio BOSTON, MA 8,039,8048.0m $655.3m $655.3m 0.03% Added +773.2k +773,152
4 VANGUARD PORTFOLIO MANAGEMENT LLC 0.02% of their portfolio MALVERN, PA 6,351,3556.4m $517.7m $517.7m 0.02% Reduced -794.8k -794,781
5 VANGUARD CAPITAL MANAGEMENT LLC 0.01% of their portfolio MALVERN, PA 6,110,9536.1m $498.1m $498.1m 0.01% Added +78.5k +78,537
6 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 5,694,6405.7m $464.2m $464.2m 0.01% Reduced -801.5k -801,490
7 NORGES BANK 0.03% of their portfolio OSLO, Q8 3,896,5363.9m $317.6m $317.6m 0.03% Not comparable
8 Invesco Ltd. 0.03% of their portfolio ATLANTA, GA 3,883,9763.9m $316.6m $316.6m 0.03% Added +603.3k +603,329
9 GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio BOSTON, MA 3,530,6123.5m $298.8m $298.8m 0.02% Reduced -748.2k -748,216
10 FRED ALGER MANAGEMENT, LLC 0.90% of their portfolio NEW YORK, NY 3,301,9193.3m $269.1m $269.1m 0.90% Reduced -40.6k -40,574
11 BAKER BROS. ADVISORS LP 0.81% of their portfolio NEW YORK, NY 1,992,7832.0m $162.4m $162.4m 0.81% Unchanged
12 Siren, L.L.C. 2.84% of their portfolio New York, NY 1,715,4761.7m $139.8m $139.8m 2.84% Added +100.0k +100,000
13 Vestal Point Capital, LP 3.00% of their portfolio NEW YORK, NY 1,575,0001.6m $128.4m $128.4m 3.00% Reduced -700.0k -700,000
14 DEERFIELD MANAGEMENT COMPANY, L.P. 1.18% of their portfolio New York, NY 1,389,0551.4m $113.2m $113.2m 1.18% Reduced -184.2k -184,242
15 FIRST TRUST ADVISORS LP 0.06% of their portfolio Wheaton, IL 1,352,9181.4m $110.3m $110.3m 0.06% Added +1.2m +1,203,770
16 Driehaus Capital Management LLC 0.64% of their portfolio Chicago, IL 1,350,5561.4m $110.1m $110.1m 0.64% Added +160.2k +160,221
17 Jupiter Topco LLC 0.04% of their portfolio NEW YORK, NY 1,221,5961.2m $99.6m $99.6m 0.04% First filing
18 NORTHERN TRUST CORP 0.01% of their portfolio CHICAGO, IL 1,192,8681.2m $97.2m $97.2m 0.01% Reduced -463.0k -462,969
19 DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio AUSTIN, TX 1,181,6081.2m $96.3m $96.3m 0.02% Added +573.1k +573,077
20 GOLDMAN SACHS GROUP INC 0.01% of their portfolio NEW YORK, NY 1,150,0071.2m $93.7m $93.7m 0.01% Reduced -589.9k -589,916
21 BANK OF AMERICA CORP /DE/ 0.01% of their portfolio CHARLOTTE, NC 1,139,8101.1m $92.9m $92.9m 0.01% Added +75.4k +75,355
22 Hood River Capital Management LLC 0.66% of their portfolio PALM BEACH GARDENS, FL 1,120,7471.1m $91.4m $91.4m 0.66% Added +64.2k +64,213
23 Holocene Advisors, LP 0.21% of their portfolio New York, NY 1,106,1771.1m $90.2m $90.2m 0.21% New
24 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 1,084,8351.1m $88.4m $88.4m 0.00% Added +124.3k +124,328
25 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio NEW YORK, NY 964,479964.5k $78.6m $78.6m 0.01% Reduced -366.5k -366,517
26 Fisher Asset Management, LLC 0.02% of their portfolio PLANO, TX 957,691957.7k $78.1m $78.1m 0.02% Reduced -155.9k -155,877
27 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio SAN FRANCISCO, CA 923,927923.9k $75.3m $75.3m 0.01% Reduced -268.2k -268,158
28 VANGUARD FIDUCIARY TRUST CO 0.02% of their portfolio MALVERN, PA 896,738896.7k $73.1m $73.1m 0.02% Reduced -69.0k -69,037
29 UBS Group AG 0.01% of their portfolio ZURICH, V8 861,520861.5k $70.2m $70.2m 0.01% Reduced -474.8k -474,751
30 Bank of New York Mellon Corp 0.01% of their portfolio NEW YORK, NY 859,538859.5k $70.1m $70.1m 0.01% Reduced -100.6k -100,606
31 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 853,360853.4k $69.6m $69.6m 0.01% Reduced -190.4k -190,372
32 SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 1.76% of their portfolio Boston, MA 830,247830.2k $67.7m $67.7m 1.76% Added +290.1k +290,103
33 Western Financial Corp/CA 19.58% of their portfolio SAN DIEGO, CA 820,239820.2k $66.9m $66.9m 19.58% Unchanged
34 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 637,399637.4k $51.8m $51.8m 0.00% Reduced -45.7k -45,669
35 Connor, Clark & Lunn Investment Management Ltd. 0.10% of their portfolio VANCOUVER, A1 625,569625.6k $51.0m $51.0m 0.10% Reduced -211.4k -211,412
36 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.04% of their portfolio BALA CYNWYD, PA 596,573596.6k $48.6m $48.6m 0.04% Added +217.7k +217,740
37 TWO SIGMA INVESTMENTS, LP 0.04% of their portfolio NEW YORK, NY 580,609580.6k $47.3m $47.3m 0.04% Added +544.8k +544,809
38 Pictet Asset Management Holding SA 0.04% of their portfolio CAROUGE, V8 573,419573.4k $46.7m $46.7m 0.04% Reduced -699.8k -699,847
39 BNP PARIBAS FINANCIAL MARKETS 0.02% of their portfolio PARIS, I0 558,643558.6k $45.5m $45.5m 0.02% Reduced -92.0k -91,956
40 LORD, ABBETT & CO. LLC 0.13% of their portfolio JERSEY CITY, NJ 540,466540.5k $44.1m $44.1m 0.13% Added +227.6k +227,642
41 1832 Asset Management L.P. 0.05% of their portfolio TORONTO, A6 538,500538.5k $43.9m $43.9m 0.05% New
42 PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio DES MOINES, IA 514,658514.7k $41.9m $41.9m 0.02% Added +24.5k +24,536
43 HRT FINANCIAL LP 0.10% of their portfolio NEW YORK, NY 498,655498.7k $40.6m $40.6m 0.10% New
44 VOYA INVESTMENT MANAGEMENT LLC 0.03% of their portfolio ATLANTA, GA 483,495483.5k $39.4m $39.4m 0.03% Reduced -172.6k -172,634
45 Balyasny Asset Management L.P. 0.07% of their portfolio Chicago, IL 470,754470.8k $38.4m $38.4m 0.07% Added +264.3k +264,342
46 RENAISSANCE TECHNOLOGIES LLC 0.05% of their portfolio NEW YORK, NY 468,921468.9k $38.2m $38.2m 0.05% Reduced -567.6k -567,574
47 FRANKLIN RESOURCES INC 0.01% of their portfolio San Mateo, CA 462,133462.1k $37.7m $37.7m 0.01% Reduced -574 -574
48 D. E. Shaw & Co., Inc. 0.02% of their portfolio New York, NY 431,560431.6k $35.2m $35.2m 0.02% Reduced -752.3k -752,278
49 Nuveen, LLC 0.01% of their portfolio CHARLOTTE, NC 415,883415.9k $33.9m $33.9m 0.01% Reduced -84.0k -83,954
50 Assenagon Asset Management S.A. 0.02% of their portfolio SENNINGERBERG, N4 403,854403.9k $32.9m $32.9m 0.02% Added +345.1k +345,119
51 RHUMBLINE ADVISERS 0.02% of their portfolio BOSTON, MA 374,897374.9k $30.6m $30.6m 0.02% Reduced -29.5k -29,539
52 EVENTIDE ASSET MANAGEMENT, LLC 0.40% of their portfolio Boston, MA 370,000370.0k $30.2m $30.2m 0.40% Unchanged
53 AMERICAN CENTURY COMPANIES INC 0.01% of their portfolio KANSAS CITY, MO 364,211364.2k $29.7m $29.7m 0.01% Reduced -287.3k -287,333
54 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 329,337329.3k $26.8m $26.8m 0.02% New
55 LPL Financial LLC 0.01% of their portfolio FORT MILL, SC 310,761310.8k $25.3m $25.3m 0.01% Added +181.3k +181,262
56 Artisan Partners Limited Partnership 0.04% of their portfolio Milwaukee, WI 310,706310.7k $25.3m $25.3m 0.04% New
57 MARSHALL WACE, LLP 0.02% of their portfolio LONDON, X0 305,031305.0k $24.9m $24.9m 0.02% Added +125.5k +125,458
58 SEI INVESTMENTS CO 0.02% of their portfolio OAKS, PA 300,619300.6k $24.5m $24.5m 0.02% Added +97.4k +97,399
59 NORDEA INVESTMENT MANAGEMENT AB 0.02% of their portfolio STOCKHOLM, V7 284,175284.2k $23.6m $23.6m 0.02% Reduced -22.3k -22,264
60 Russell Investments Group, Ltd. 0.02% of their portfolio Seattle, WA 284,096284.1k $23.2m $23.2m 0.02% Added +110.1k +110,101
61 CITIGROUP INC 0.01% of their portfolio NEW YORK, NY 264,678264.7k $21.6m $21.6m 0.01% Added +13.1k +13,110
62 California Public Employees Retirement System 0.01% of their portfolio Sacramento, CA 256,314256.3k $20.9m $20.9m 0.01% Reduced -819 -819
63 Squarepoint Ops LLC 0.04% of their portfolio NEW YORK, NY 255,907255.9k $20.9m $20.9m 0.04% New
64 ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio Berwyn, PA 254,228254.2k $20.7m $20.7m 0.00% Added +187.5k +187,478
65 Aberdeen Group plc 0.03% of their portfolio EDINBURGH, X0 251,968252.0k $20.5m $20.5m 0.03% Reduced -112.0k -112,004
66 Swiss National Bank 0.01% of their portfolio ZURICH, V8 238,900238.9k $19.5m $19.5m 0.01% Reduced -3.1k -3,100
67 Legal & General Group Plc 0.00% of their portfolio London, X0 237,216237.2k $19.3m $19.3m 0.00% Added +8.1k +8,119
68 Privium Fund Management B.V. 3.51% of their portfolio AMSTERDAM, P7 234,222234.2k $19.1m $19.1m 3.51% Reduced -132.7k -132,714
69 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.01% of their portfolio BOSTON, MA 218,133218.1k $17.8m $17.8m 0.01% Reduced -369.0k -368,992
70 Life Cycle Investment Partners Ltd 0.08% of their portfolio LONDON, X0 209,068209.1k $17.0m $17.0m 0.08% New
71 HSBC HOLDINGS PLC 0.01% of their portfolio LONDON, X0 203,800203.8k $16.8m $16.8m 0.01% Added +52.8k +52,754
72 Woodline Partners LP 0.05% of their portfolio San Francisco, CA 200,184200.2k $16.3m $16.3m 0.05% Unchanged
73 Integral Health Asset Management, LLC 0.67% of their portfolio New York, NY 200,000200.0k $16.3m $16.3m 0.67% Reduced -100.0k -100,000
74 AQR CAPITAL MANAGEMENT LLC 0.01% of their portfolio Greenwich, CT 198,842198.8k $15.8m $15.8m 0.01% Added +31.6k +31,632
75 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 196,205196.2k $16.0m $16.0m 0.01% Added +180.4k +180,430
76 MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC 0.15% of their portfolio New York, NY 191,432191.4k $15.6m $15.6m 0.15% Added +7.1k +7,128
77 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 173,265173.3k $10.9m $10.9m 0.00% Reduced -107.1k -107,129
78 WCM INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio LAGUNA BEACH, CA 171,232171.2k $13.8m $13.8m 0.02% Reduced -343 -343
79 PINNACLE ASSOCIATES LTD 0.15% of their portfolio NEW YORK, NY 170,131170.1k $13.9m $13.9m 0.15% Reduced -5.3k -5,325
80 RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio ST. PETERSBURG, FL 169,913169.9k $13.8m $13.8m 0.00% Reduced -12.6k -12,642
81 SEB Asset Management AB 0.05% of their portfolio STOCKHOLM, V7 158,205158.2k $12.9m $12.9m 0.05% Unchanged
82 Clearbridge Investments, LLC 0.01% of their portfolio NEW YORK, NY 157,110157.1k $12.8m $12.8m 0.01% Reduced -45.2k -45,237
83 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 155,908155.9k $12.7m $12.7m 0.00% Reduced -35.1k -35,146
84 Affinity Asset Advisors, LLC 0.60% of their portfolio NEW YORK, NY 150,000150.0k $12.2m $12.2m 0.60% Reduced -50.0k -50,000
85 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 149,240149.2k $12.2m $12.2m 0.00% Reduced -110.7k -110,723
86 WEALTH EFFECTS LLC 3.24% of their portfolio BOSTON, MA 147,300147.3k $12.0m $12.0m 3.24% Added +4.0k +4,000
87 Retirement Systems of Alabama 0.04% of their portfolio MONTGOMERY, AL 145,687145.7k $11.9m $11.9m 0.04% Reduced -26.0k -25,985
88 TORONTO DOMINION BANK 0.02% of their portfolio TORONTO, ONTARIO, A6 144,928144.9k $11.8m $11.8m 0.02% Reduced -5.3k -5,350
89 HighTower Advisors, LLC 0.01% of their portfolio CHICAGO, IL 140,394140.4k $11.4m $11.4m 0.01% Reduced -6.1k -6,068
90 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio WEST SACRAMENTO, CA 139,826139.8k $11.4m $11.4m 0.01% Reduced -4.5k -4,487
91 Weiss Asset Management LP 0.12% of their portfolio BOSTON, MA 134,014134.0k $10.9m $10.9m 0.12% Not comparable
92 BANK OF NOVA SCOTIA 0.02% of their portfolio TORONTO, A6 133,805133.8k $10.9m $10.9m 0.02% Reduced -2.2k -2,155
93 PFM Health Sciences, LP 0.93% of their portfolio SAN FRANCISCO, CA 131,667131.7k $10.7m $10.7m 0.93% Added +67.4k +67,388
94 Tetragon Partners GP Ltd 1.73% of their portfolio GRAND CAYMAN, E9 130,484130.5k $10.6m $10.6m 1.73% Added +3.3k +3,286
95 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 128,789128.8k $10.5m $10.5m 0.00% Reduced -29.6k -29,609
96 Rhenman & Partners Asset Management AB 0.98% of their portfolio Stockholm, V7 128,000128.0k $10.4m $10.4m 0.98% Reduced -16.5k -16,500
97 VANGUARD ASSET MANAGEMENT, Ltd 0.01% of their portfolio London, EC4N 8AF, X0 119,102119.1k $9.7m $9.7m 0.01% Added +6.1k +6,131
98 Catalyst Funds Management Pty Ltd 0.54% of their portfolio SYDNEY NSW, C3 117,600117.6k $9.6m $9.6m 0.54% New
99 NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio ALBANY, NY 116,948116.9k $9.5m $9.5m 0.02% Reduced -7.9k -7,905
100 Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% of their portfolio FRANKFURT AM MAIN, 2M 116,393116.4k $9.5m $9.5m 0.01% Reduced -3.8k -3,845