MACROGENICS INC MGNX
COM · Common Stock · CUSIP 556099109 · ISIN US5560991094
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersRockville, MD
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($259.2k this quarter). Holder counts are more reliable. Shares outstanding: 63.7m as of 2026-08-08, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $4.62. Options: 5 managers hold calls ($316.5k notional), 3 hold puts ($132.6k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 135 |
| Q4 2022 | 137 |
| Q1 2023 | 138 |
| Q2 2023 | 132 |
| Q3 2023 | 129 |
| Q4 2023 | 143 |
| Q1 2024 | 164 |
| Q2 2024 | 148 |
| Q3 2024 | 125 |
| Q4 2024 | 130 |
| Q1 2025 | 130 |
| Q2 2025 | 113 |
| Q3 2025 | 104 |
| Q4 2025 | 89 |
| Q1 2026 | 109 |
| Q2 2026 | 122 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 50 | 82 |
| Q4 2024 | 55 | 57 |
| Q1 2025 | 53 | 58 |
| Q2 2025 | 53 | 77 |
| Q3 2025 | 47 | 50 |
| Q4 2025 | 41 | 50 |
| Q1 2026 | 57 | 38 |
| Q2 2026 | 72 | 54 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $114.6k | $164.9k | 1.44 |
| Q4 2025 | $147.6k | $24.3k | 0.16 |
| Q1 2026 | $599.7k | $43.9k | 0.07 |
| Q2 2026 | $316.5k | $132.6k | 0.42 |
Biggest buyers
| BlackRock, Inc. | Added | +3.5m |
| MACKENZIE FINANCIAL CORP | Added | +1.0m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +879.2k |
| Affinity Asset Advisors, LLC | Added | +716.6k |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Added | +611.5k |
| STATE STREET CORP | Added | +570.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Added | +561.1k |
| WASATCH ADVISORS LP | Added | +459.2k |
| NORTHERN TRUST CORP | Added | +363.8k |
| GOLDMAN SACHS GROUP INC | Added | +284.5k |
Biggest sellers
| ARMISTICE CAPITAL, LLC | Reduced | -1.0m |
| CITADEL ADVISORS LLC | Reduced | -602.8k |
| JANE STREET GROUP, LLC | Reduced | -524.6k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -420.1k |
| MARSHALL WACE, LLP | Reduced | -409.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -398.6k |
| GSA CAPITAL PARTNERS LLP | Sold out | -379.6k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -330.8k |
| Vestal Point Capital, LP | Sold out | -280.0k |
| UBS Group AG | Reduced | -254.3k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $126.6k27.4k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $107.2k23.2k shares |
| GROUP ONE TRADING LLC | Reduced | $63.3k13.7k shares |
| Walleye Capital LLC | Reduced | $11.1k2.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $8.3k1.8k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $81.8k17.7k shares |
| CITADEL ADVISORS LLC | New | $49.0k10.6k shares |
| SIMPLEX TRADING, LLC | Reduced | $1.8k400 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARMISTICE CAPITAL, LLC 13G · institution -1.6 pts · filed 2026-08-14 | 7.9% |
| BlackRock, Inc. 13G · institution +4.2 pts · filed 2026-07-29 | 7.1% |
Fell to 5% or below in the last year: BANK OF AMERICA CORP /DE/ (4.0%, 2026-08-03), MILLENNIUM MANAGEMENT LLC (3.7%, 2026-07-20), VANGUARD GROUP INC (0.0%, 2026-03-27), Frazier Life Sciences Public Fund, L.P. (0.0%, 2026-02-13), Bellevue Group AG (0.0%, 2026-01-06), WASATCH ADVISORS LP (3.1%, 2025-11-12)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 1 | $1.1k | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 1 | $150.5k | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 1 | $129.1k | $129.1k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-08-19 | Peters Jeffrey Stuart Senior VP, GC, and Secretary | Sold plan | $129.1k31.1k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| ARMISTICE CAPITAL, LLC 0.64% of their portfolio | 5.0m $23.1m | Reduced -1.0m |
| BlackRock, Inc. 0.00% of their portfolio | 4.7m $21.6m | Added +3.5m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.7m $12.3m | Added +2.2k |
| RENAISSANCE TECHNOLOGIES LLC 0.02% of their portfolio | 2.6m $12.2m | Reduced -330.8k |
| ACADIAN ASSET MANAGEMENT LLC 0.01% of their portfolio | 2.5m $11.7m | Reduced -1.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 2.5m $11.5m | Added +86.4k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 2.5m $11.4m | Reduced -62.1k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 2.4m $11.0m | Reduced -420.1k |
| WASATCH ADVISORS LP 0.06% of their portfolio | 2.0m $9.3m | Added +459.2k |
| RA CAPITAL MANAGEMENT, L.P. 0.07% of their portfolio | 1.9m $8.6m | Unchanged |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.8m $8.4m | Added +611.5k |
| MACKENZIE FINANCIAL CORP 0.01% of their portfolio | 1.6m $7.6m | Added +1.0m |
| MARSHALL WACE, LLP 0.01% of their portfolio | 1.6m $7.5m | Reduced -409.3k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.6m $7.3m | Added +879.2k |
| Affinity Asset Advisors, LLC 0.27% of their portfolio | 1.2m $5.6m | Added +716.6k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 1.1m $4.9m | Added +4.6k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.02% of their portfolio | 1.0m $4.6m | Added +561.1k |
| Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio | 1.0m $4.6m | Added +133.2k |
| STATE STREET CORP 0.00% of their portfolio | 863.7k $4.0m | Added +570.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 558.0k $2.6m | Added +284.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 516.1k $2.4m | Added +363.8k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 420.1k $1.9m | Added +80.0k |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.00% of their portfolio | 420.0k $1.9m | Unchanged |
| Walleye Capital LLC 0.01% of their portfolio | 408.1k $1.9m | Added +72.9k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 379.3k $1.8m | Added +127.5k |
| DIADEMA PARTNERS LP 0.61% of their portfolio | 374.4k $1.7m | Reduced -225.6k |
| PINNACLE ASSOCIATES LTD 0.01% of their portfolio | 254.3k $1.2m | Reduced -24.8k |
| PANAGORA ASSET MANAGEMENT INC 0.00% of their portfolio | 250.2k $1.2m | Added +65.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 192.6k $890.0k | Added +152.6k |
| Man Group plc 0.00% of their portfolio | 188.2k $869.4k | Added +140.2k |
| Amundi 0.00% of their portfolio | 181.2k $837.4k | Reduced -33.0k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 179.8k $830.8k | Reduced -602.8k |
| Informed Momentum Co LLC 0.07% of their portfolio | 171.7k $793.3k | New |
| LPL Financial LLC 0.00% of their portfolio | 170.3k $786.6k | Added +10.6k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 164.7k $760.9k | Added +133.4k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 147.1k $679.0k | Added +147.0k |
| STRS OHIO 0.00% of their portfolio | 142.5k $658.4k | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 135.6k $626.3k | New |
| Nuveen, LLC 0.00% of their portfolio | 131.8k $608.7k | New |
| ADAR1 Capital Management, LLC 0.03% of their portfolio | 129.8k $599.8k | Added +89.8k |
| Squarepoint Ops LLC 0.00% of their portfolio | 117.4k $542.3k | Reduced -66.5k |
| Invesco Ltd. 0.00% of their portfolio | 103.0k $475.8k | Reduced -9.4k |
| Headlands Technologies LLC 0.05% of their portfolio | 99.2k $458.2k | Added +51.7k |
| Susquehanna Portfolio Strategies, LLC 0.01% of their portfolio | 96.7k $446.7k | Added +78.3k |
| Persistent Asset Partners Ltd 0.14% of their portfolio | 95.4k $440.6k | Reduced -56.4k |
| MORGAN STANLEY 0.00% of their portfolio | 92.8k $428.7k | Reduced -76.3k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 83.9k $387.4k | Reduced -524.6k |
| FMR LLC 0.00% of their portfolio | 83.6k $386.3k | Added +22.9k |
| XTX Topco Ltd 0.00% of their portfolio | 76.1k $351.4k | Reduced -101.8k |
| Ikarian Capital, LLC 0.06% of their portfolio | 74.9k $346.0k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 73.5k $339.6k | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 67.9k $313.8k | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 66.1k $305.4k | New |
| ALPS ADVISORS INC 0.00% of their portfolio | 64.5k $298.0k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 62.3k $288.0k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 62.3k $287.9k | Added +60.9k |
| Velan Capital Investment Management LP 0.17% of their portfolio | 60.0k $277.2k | Added +30.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 59.7k $275.7k | Added +56.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 53.6k $247.7k | Reduced -398.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 51.6k $239.0k | New |
| Leonteq Securities AG 0.01% of their portfolio | 50.0k $231.0k | Unchanged |
| Marex Group Ltd 0.00% of their portfolio | 50.0k $231.0k | Reduced -50.0k |
| BARCLAYS PLC 0.00% of their portfolio | 49.8k $230.2k | Reduced -12.8k |
| Graham Capital Management, L.P. 0.01% of their portfolio | 47.5k $219.2k | Added +36.3k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 44.2k $204.2k | New |
| UBS Group AG 0.00% of their portfolio | 41.8k $193.3k | Reduced -254.3k |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 38.8k $179.4k | Added +34.1k |
| AlphaCore Capital LLC 0.00% of their portfolio | 37.8k $174.4k | Unchanged |
| MetLife Investment Management, LLC 0.00% of their portfolio | 37.3k $172.5k | New |
| CANADA PENSION PLAN INVESTMENT BOARD 0.00% of their portfolio | 37.0k $170.9k | Reduced -69.4k |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main 0.00% of their portfolio | 36.5k $168.5k | New |
| Corient Private Wealth LP 0.00% of their portfolio | 30.0k $138.6k | Reduced -1.8k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.00% of their portfolio | 29.9k $138.1k | New |
| CITIGROUP INC 0.00% of their portfolio | 29.4k $135.8k | Reduced -4.1k |
| nVerses Capital, LLC 0.21% of their portfolio | 29.1k $134.4k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 28.8k $133.1k | New |
| Allspring Global Investments Holdings, LLC 0.00% of their portfolio | 28.2k $130.2k | New |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 27.8k $128.3k | Added +5.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 26.4k $128.2k | Added +2.6k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 26.3k $121.5k | New |
| Cresset Asset Management, LLC 0.00% of their portfolio | 25.8k $119.3k | New |
| XML Financial, LLC 0.01% of their portfolio | 24.8k $114.7k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 24.3k $112.3k | Reduced -3.3k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 22.8k $105.4k | Unchanged |
| Lantern Wealth Advisors, LLC 0.05% of their portfolio | 22.7k $104.9k | Reduced -4.0k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 18.5k $85.6k | New |
| BOOTHBAY FUND MANAGEMENT, LLC 0.00% of their portfolio | 18.3k $84.7k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 17.7k $81.7k | New |
| Evercore Wealth Management, LLC 0.00% of their portfolio | 17.5k $81.0k | Unchanged |
| Spark Investment Management LLC 0.16% of their portfolio | 17.2k $79.5k | New |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 16.3k $75.5k | Reduced -80 |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 15.8k $45.6k | New |
| Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio | 14.9k $68.8k | Reduced -264 |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 14.5k $67.0k | Reduced -2.1k |
| Verdad Advisers, LP 0.06% of their portfolio | 14.4k $66.7k | New |
| TWO SIGMA SECURITIES, LLC 0.01% of their portfolio | 13.7k $63.1k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 12.2k $56.6k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 11.7k $54.1k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 11.5k $53.3k | New |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.00% of their portfolio | 11.4k $52.8k | New |