Venrock Adviser, LLC

NEW YORK, NY · CIK 1615982 · 13F filing filed 2025-08-14

SEC-registered investment adviser since 2014 · limited liability company

Assets managed$4.5bn
Staff11 · 11 in investment roles
Main clients (by assets)Private funds 100%
Private funds7 (1 hedge) · $4.5bn gross assets
Form ADV · 2026-04-28SEC adviser record

Legal entityVENROCK ADVISER, LLC (US)

$1.3bn reported value +13.5% vs Q1 2025

31positions

74.6%in top 10

4 new 4 added 6 reduced 10 sold out vs Q1 2025

Holdings, Q2 2025

The small lines show how much was held over the last 4 quarters (adjusted for stock splits).

#	Security	Ticker	Shares	Value	% of portfolio	Change	Shares change
1	APOGEE THERAPEUTICS INC COM COM		8,493,321	$368.9m27.64%	27.64%	Unchanged
2	OCULAR THERAPEUTIX INC COM OCUL	OCUL	12,762,462	$118.4m8.88%	8.88%	Unchanged
3	METSERA INC COM COM		3,750,662	$106.7m8.00%	8.00%	Unchanged
4	ENLIVEN THERAPEUTICS INC COM ELVN	ELVN	4,026,331	$80.8m6.05%	6.05%	Unchanged
5	KALVISTA PHARMACEUTICALS INC COM KALV	KALV	6,728,985	$76.1m5.70%	5.70%	Added +25.0k	+25,000 0.4%
6	ORIC PHARMACEUTICALS INC COM ORIC	ORIC	6,596,885	$67.0m5.02%	5.02%	Added +3.4m	+3,414,358 107.3%
7	VIRIDIAN THERAPEUTICS INC COM VRDN	VRDN	3,882,709	$54.3m4.07%	4.07%	Unchanged
8	ORUKA THERAPEUTICS INC COM ORKA	ORKA	4,148,428	$46.5m3.48%	3.48%	Unchanged
9	SPYRE THERAPEUTICS INC COM NEW SYRE	SYRE	2,685,448	$40.2m3.01%	3.01%	Unchanged
10	PHARVARIS N V COM PHVS	PHVS	2,047,620	$36.0m2.70%	2.70%	Reduced -1.1m	-1,065,100 -34.2%
11	COGENT BIOSCIENCES INC COM COGT	COGT	4,755,411	$34.1m2.56%	2.56%	Reduced -929.0k	-929,000 -16.3%
12	JADE BIOSCIENCES INC COM NEW JBIO	JBIO	3,220,364	$32.2m2.41%	2.41%	New
13	CYTOMX THERAPEUTICS INC COM CTMX	CTMX	13,969,882	$31.7m2.38%	2.38%	New
14	CIDARA THERAPEUTICS INC COM NEW CDTX	CDTX	639,088	$31.1m2.33%	2.33%	Reduced -412.4k	-412,430 -39.2%
15	UPSTREAM BIO INC COM UPB	UPB	2,295,319	$25.2m1.89%	1.89%	Unchanged
16	ERASCA INC COM ERAS	ERAS	17,857,083	$22.7m1.70%	1.70%	Added +1.6m	+1,640,867 10.1%
17	CRESCENT BIOPHARMA INC. COM CBIO	CBIO	1,387,864	$22.4m1.68%	1.68%	New
18	DYNE THERAPEUTICS INC COM DYN	DYN	2,173,913	$20.7m1.55%	1.55%	Unchanged
19	SAVARA INC COM SVRA	SVRA	8,884,263	$20.3m1.52%	1.52%	Added +5.6m	+5,626,624 172.7%
20	DIANTHUS THERAPEUTICS INC COM DNTH	DNTH	1,000,000	$18.6m1.40%	1.40%	Reduced -744.4k	-744,373 -42.7%
21	ENGENE HOLDINGS INC COM COM		5,046,414	$18.4m1.38%	1.38%	Unchanged
22	ASTRIA THERAPEUTICS INC COM CATB	CATB	2,457,348	$13.2m0.99%	0.99%	Unchanged
23	CULLINAN THERAPEUTICS INC COM CGEM	CGEM	1,379,965	$10.4m0.78%	0.78%	Unchanged
24	ABIVAX SA SPONSORED ADS ABVX	ABVX	1,345,780	$10.3m0.77%	0.77%	Unchanged
25	PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS FRNM	FRNM	750,000	$8.0m0.60%	0.60%	Unchanged
26	SEPTERNA INC COM SEPN	SEPN	540,453	$5.7m0.43%	0.43%	New
27	SURROZEN INC COM NEW SRZN	SRZN	632,931	$5.7m0.42%	0.42%	Unchanged
28	ZURA BIO LTD CLASS A ORD SHS ZURA	ZURA	4,631,216	$4.9m0.36%	0.36%	Reduced -391.9k	-391,950 -7.8%
29	ARTIVA BIOTHERAPEUTICS INC COM ARTV	ARTV	1,609,569	$2.4m0.18%	0.18%	Unchanged
30	CASI PHARMACEUTICALS INC ORD SHS CASIF	CASIF	987,259	$1.2m0.09%	0.09%	Unchanged
31	TENAX THERAPEUTICS INC COM NEW TENX	TENX	98,564	$567.7k0.04%	0.04%	Reduced -109.8k	-109,769 -52.7%

Sold out since Q1 2025

Security	Ticker	Shares held before	Value then
PRAXIS PRECISION MEDICINES I PRAX	PRAX	989,985	$37.5m990.0k shares
SOLID BIOSCIENCES INC SLDB	SLDB	2,481,400	$9.2m2.5m shares
TREVI THERAPEUTICS INC TRVI	TRVI	615,506	$3.9m615.5k shares
APPLIED THERAPEUTICS INC APLT	APLT	5,567,709	$2.7m5.6m shares
4D MOLECULAR THERAPEUTICS IN FDMT	FDMT	677,600	$2.2m677.6k shares
MERSANA THERAPEUTICS INC		3,574,325	$1.2m3.6m shares
CENTURY THERAPEUTICS INC IPSC	IPSC	2,498,069	$1.2m2.5m shares
TENAYA THERAPEUTICS INC TNYA	TNYA	1,555,556	$886.8k1.6m shares
GLYCOMIMETICS INC		3,000,000	$630.0k3.0m shares
INSTIL BIO INC TIL	TIL	33,177	$576.0k33.2k shares