JADE BIOSCIENCES INC JBIO
COM NEW · Common Stock · CUSIP 008064206
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWaltham, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($71.1k this quarter). Holder counts are more reliable. Shares outstanding: 32.6m as of 2025-08-08, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $9.99. Options: 1 managers hold calls ($0 notional), 5 hold puts ($1.5m).
Trends to Q2 2025
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $0 | $0 | — |
| Q4 2024 | $0 | $0 | — |
| Q1 2025 | $0 | $0 | — |
| Q2 2025 | $0 | $1.5m | — |
Biggest buyers
| FMR LLC | New | +4.8m |
| Fairmount Funds Management LLC | New | +3.2m |
| Venrock Adviser, LLC | New | +3.2m |
| Deep Track Capital, LP | New | +2.5m |
| VANGUARD GROUP INC | New | +1.8m |
| Frazier Life Sciences Management, L.P. | New | +1.8m |
| BlackRock, Inc. | New | +1.7m |
| Versant Venture Management, LLC | New | +1.5m |
| RTW INVESTMENTS, LP | New | +1.4m |
| Driehaus Capital Management LLC | New | +1.3m |
Biggest sellers
| None |
Biggest calls
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | New | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $582.4k58.3k shares |
| Persistent Asset Partners Ltd | New | $452.2k12.4k shares |
| SIMPLEX TRADING, LLC | New | $258.0k25.9k shares |
| GROUP ONE TRADING LLC | New | $231.8k23.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | New | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Fairmount Funds Management LLC 13D · may seek influence no change · filed 2026-06-09 | 20.0% |
| FMR LLC 13G · institution new · filed 2025-06-06 | 14.7% |
| Janus Henderson Group Ltd. 13G · institution +4.3 pts · filed 2026-07-08 | 10.6% |
| Venrock Healthcare Capital Partners III, L.P. 13G · passive investor -1.6 pts · filed 2026-08-14 | 8.3% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor +2.9 pts · filed 2025-10-16 | 7.0% |
| FRANKLIN TEMPLETON INC 13G · institution new · filed 2026-10-28 | 6.0% |
| BlackRock, Inc. 13G · institution +0.5 pts · filed 2026-10-27 | 5.2% |
| Paradigm Biocapital Advisors LP 13G · passive investor new · filed 2026-07-17 | 5.1% |
| Bellevue Group AG 13G · institution -1.8 pts · filed 2026-08-14 | 5.0% |
Fell to 5% or below in the last year: Sofinnova Venture Partners X, L.P. (0.3%, 2026-03-05), Deep Track Capital, LP (0.0%, 2026-02-13), VANGUARD GROUP INC (4.2%, 2026-01-30), Frazier Life Sciences Public Fund, L.P. (4.2%, 2025-11-14)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 3 | $790.0k | $790.0k |
| Q4 2023 | 0 | — | 5 | $1.2m | $1.2m |
| Q1 2024 | 0 | — | 5 | $3.2m | $3.2m |
| Q2 2024 | 1 | $1.5m | 6 | $3.3m | $3.0m |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 1 | $44.4k | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-05-16 | Frohlich Tom Chief Executive Officer, director | Bought | $44.4k6.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.00% of their portfolio | 4.8m $48.3m | New |
| Fairmount Funds Management LLC 4.17% of their portfolio | 3.2m $32.2m | New |
| Venrock Adviser, LLC 2.41% of their portfolio | 3.2m $32.2m | New |
| Deep Track Capital, LP 0.81% of their portfolio | 2.5m $25.1m | New |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.8m $18.1m | New |
| Frazier Life Sciences Management, L.P. 0.71% of their portfolio | 1.8m $17.7m | New |
| BlackRock, Inc. 0.00% of their portfolio | 1.7m $17.1m | New |
| Versant Venture Management, LLC 18.56% of their portfolio | 1.5m $15.2m | New |
| RTW INVESTMENTS, LP 0.21% of their portfolio | 1.4m $14.5m | New |
| Driehaus Capital Management LLC 0.10% of their portfolio | 1.3m $12.5m | New |
| Avidity Partners Management LP 2.26% of their portfolio | 1.1m $11.3m | New |
| RA CAPITAL MANAGEMENT, L.P. 0.18% of their portfolio | 1.1m $10.6m | New |
| Soleus Capital Management, L.P. 0.55% of their portfolio | 796.7k $8.0m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 676.4k $6.8m | New |
| Logos Global Management LP 0.83% of their portfolio | 625.0k $6.2m | New |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.10% of their portfolio | 531.2k $5.3m | New |
| ORBIMED ADVISORS LLC 0.13% of their portfolio | 531.2k $5.3m | New |
| SAMSARA BIOCAPITAL, LLC 1.09% of their portfolio | 531.2k $5.3m | New |
| GREAT POINT PARTNERS LLC 3.24% of their portfolio | 498.1k $5.0m | New |
| STATE STREET CORP 0.00% of their portfolio | 318.8k $3.2m | New |
| BARCLAYS PLC 0.00% of their portfolio | 274.8k $2.7m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 228.1k $2.3m | New |
| Sofinnova Investments, Inc. 0.07% of their portfolio | 107.4k $1.1m | New |
| Woodline Partners LP 0.01% of their portfolio | 106.3k $1.1m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 103.3k $1.0m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 78.4k $783.1k | New |
| Affinity Asset Advisors, LLC 0.10% of their portfolio | 65.3k $652.5k | New |
| TCG Crossover Management, LLC 0.07% of their portfolio | 64.0k $639.6k | New |
| Nuveen, LLC 0.00% of their portfolio | 60.1k $600.7k | New |
| MORGAN STANLEY 0.00% of their portfolio | 49.8k $497.2k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 44.6k $445.2k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 39.2k $391.9k | New |
| XTX Topco Ltd 0.01% of their portfolio | 25.8k $257.3k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 25.6k $255.9k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 23.0k $229.7k | New |
| Quantinno Capital Management LP 0.00% of their portfolio | 22.0k $219.6k | New |
| UBS Group AG 0.00% of their portfolio | 21.0k $210.2k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 20.8k $208.1k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 17.8k $177.4k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 16.3k $163.0k | New |
| DELTEC ASSET MANAGEMENT LLC 0.03% of their portfolio | 15.8k $157.4k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 15.4k $153.5k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 14.3k $143.4k | New |
| CITIGROUP INC 0.00% of their portfolio | 12.1k $121.3k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 12.1k $120.4k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 11.4k $114.1k | New |
| Corient Private Wealth LP 0.00% of their portfolio | 10.1k $101.2k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 7.4k $74.0k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 7.1k $71.1k | New |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 5.3k $52.6k | New |
| STRS OHIO 0.00% of their portfolio | 4.9k $49.0k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.3k $33.1k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 3.2k $32.2k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 3.1k $31.4k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 3.1k $30.9k | New |
| Legal & General Group Plc 0.00% of their portfolio | 3.0k $29.4k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 876 $8.8k | New |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 339 $3.4k | New |
| GAMMA Investing LLC 0.00% of their portfolio | 127 $1.3k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 122 $1.2k | New |
| CWM, LLC 0.00% of their portfolio | 120 $1.0k | New |
| Glenmede Investment Management, LP 0.00% of their portfolio | 53 $529 | First filing |
| ROTHSCHILD INVESTMENT LLC 0.00% of their portfolio | 30 $300 | New |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 16 $160 | New |
| PRINCIPAL SECURITIES, INC. 0.00% of their portfolio | 13 $130 | New |
| AMALGAMATED BANK 0.00% of their portfolio | 9 $0 | New |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 7 $70 | New |
| Avion Wealth 0.00% of their portfolio | 7 $0 | New |
| Capital Advisors, Ltd. LLC 0.00% of their portfolio | 6 $0 | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 4 $40 | New |
| Arax Advisory Partners 0.00% of their portfolio | 3 $30 | New |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 2 $18 | New |
| ASSETMARK, INC 0.00% of their portfolio | 1 $10 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. — of their portfolio | 0 $0 | New |