ENLIVEN THERAPEUTICS INC ELVN
COM · Common Stock · CUSIP 29337E102
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBurlingame, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($367.5k this quarter). Holder counts are more reliable. Shares outstanding: 59.2m as of 2025-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $20.06. Options: 1 managers hold calls ($0 notional), 2 hold puts ($14.0k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q1 2023 | 45 |
| Q2 2023 | 64 |
| Q3 2023 | 62 |
| Q4 2023 | 63 |
| Q1 2024 | 75 |
| Q2 2024 | 95 |
| Q3 2024 | 104 |
| Q4 2024 | 116 |
| Q1 2025 | 124 |
| Q2 2025 | 127 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 28 | 30 |
| Q4 2023 | 30 | 19 |
| Q1 2024 | 42 | 24 |
| Q2 2024 | 67 | 27 |
| Q3 2024 | 59 | 33 |
| Q4 2024 | 61 | 36 |
| Q1 2025 | 63 | 46 |
| Q2 2025 | 79 | 43 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $2.6k | $12.8k | 5.00 |
| Q4 2024 | $24.8k | $6.8k | 0.27 |
| Q1 2025 | $3.9k | $20.7k | 5.26 |
| Q2 2025 | $0 | $14.0k | — |
Biggest buyers
| Capital Research Global Investors | New | +1.3m |
| Point72 Asset Management, L.P. | Added | +1.2m |
| NOVO HOLDINGS A/S | New | +1.1m |
| FMR LLC | Added | +950.4k |
| Polar Capital Holdings Plc | Added | +685.0k |
| Blackstone Inc. | Added | +558.3k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +512.1k |
| Fairmount Funds Management LLC | Added | +508.6k |
| TCG Crossover Management, LLC | New | +498.0k |
| Duquesne Family Office LLC | New | +463.0k |
Biggest sellers
| Boxer Capital Management, LLC | Sold out | -671.4k |
| 5AM Venture Management, LLC | Reduced | -550.0k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -354.0k |
| Ikarian Capital, LLC | Sold out | -289.5k |
| ACUTA CAPITAL PARTNERS, LLC | Sold out | -265.3k |
| LORD, ABBETT & CO. LLC | Sold out | -197.3k |
| STEMPOINT CAPITAL LP | Sold out | -120.4k |
| BOOTHBAY FUND MANAGEMENT, LLC | Sold out | -77.0k |
| Russell Investments Group, Ltd. | Reduced | -76.0k |
| FEDERATED HERMES, INC. | Reduced | -53.0k |
Biggest calls
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SIMPLEX TRADING, LLC | Added | $14.0k700 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +1.7 pts · filed 2026-08-06 | 15.0% |
ORBIMED ADVISORS LLC
13D · may seek influence
-1.4 pts · filed 2026-06-24
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer either… Full filing |
9.5% |
| Polar Capital Holdings Plc 13G · institution no change · filed 2026-06-22 | 8.5% |
| Commodore Capital LP 13G · passive investor -2.2 pts · filed 2026-05-15 | 7.7% |
| BlackRock, Inc. 13G · institution +2.0 pts · filed 2026-10-27 | 7.1% |
| Vestal Point Capital, LP 13G · institution -1.1 pts · filed 2026-05-15 | 5.4% |
Fell to 5% or below in the last year: Venrock Healthcare Capital Partners III, L.P. (2.8%, 2026-05-15), Fairmount Funds Management LLC (3.1%, 2026-05-15)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 2 | $329.2k | $329.2k |
| Q4 2023 | 0 | — | 5 | $1.1m | $1.0m |
| Q1 2024 | 0 | — | 6 | $2.0m | $2.0m |
| Q2 2024 | 0 | — | 9 | $30.0m | $7.1m |
| Q3 2024 | 0 | — | 5 | $3.5m | $3.5m |
| Q4 2024 | 0 | — | 7 | $4.3m | $4.3m |
| Q1 2025 | 0 | — | 4 | $1.8m | $1.6m |
| Q2 2025 | 0 | — | 4 | $2.1m | $2.1m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-06-27 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $68.0k3.2k shares |
| 2025-06-20 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $267.5k12.5k shares |
| 2025-06-17 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $277.3k12.5k shares |
| 2025-06-13 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $67.7k3.0k shares |
| 2025-06-09 | Patel Anish CHIEF OPERATING OFFICER · See footnote | Sold plan | $135.6k6.7k shares |
| 2025-06-03 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $150.4k7.5k shares |
| 2025-06-03 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $150.2k7.5k shares |
| 2025-05-27 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $52.6k3.2k shares |
| 2025-05-19 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $82.4k5.0k shares |
| 2025-05-19 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $81.5k5.0k shares |
| 2025-05-07 | Patel Anish CHIEF OPERATING OFFICER · See footnote | Sold plan | $122.6k6.7k shares |
| 2025-05-02 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $49.4k2.5k shares |
| 2025-05-02 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $43.4k2.2k shares |
| 2025-05-01 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $107.0k5.3k shares |
| 2025-05-01 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $101.0k5.0k shares |
| 2025-04-28 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $60.7k3.2k shares |
| 2025-04-21 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $80.4k5.0k shares |
| 2025-04-17 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $82.1k5.0k shares |
| 2025-04-07 | Patel Anish CHIEF OPERATING OFFICER · See footnote | Sold plan | $120.3k6.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| ORBIMED ADVISORS LLC 4.02% of their portfolio | 8.0m $159.7m | Unchanged |
| FMR LLC 0.01% of their portfolio | 7.6m $151.7m | Added +950.4k |
| Commodore Capital LP 6.64% of their portfolio | 4.7m $94.1m | Added +17.8k |
| Venrock Adviser, LLC 6.05% of their portfolio | 4.0m $80.8m | Unchanged |
| Fairmount Funds Management LLC 9.65% of their portfolio | 3.7m $74.5m | Added +508.6k |
| Polar Capital Holdings Plc 0.32% of their portfolio | 3.1m $61.2m | Added +685.0k |
| BlackRock, Inc. 0.00% of their portfolio | 3.0m $59.5m | Reduced -31.0k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.4m $48.4m | Added +438.4k |
| JANUS HENDERSON GROUP PLC 0.02% of their portfolio | 1.7m $34.4m | Added +145.9k |
| CITADEL ADVISORS LLC 0.03% of their portfolio | 1.5m $29.5m | Added +347.3k |
| Point72 Asset Management, L.P. 0.06% of their portfolio | 1.4m $27.1m | Added +1.2m |
| Blackstone Inc. 0.12% of their portfolio | 1.3m $26.5m | Added +558.3k |
| Capital Research Global Investors 0.01% of their portfolio | 1.3m $26.4m | New |
| Woodline Partners LP 0.12% of their portfolio | 1.1m $22.1m | Added +295.5k |
| NOVO HOLDINGS A/S 1.54% of their portfolio | 1.1m $21.8m | New |
| Pictet Asset Management Holding SA 0.02% of their portfolio | 967.5k $19.4m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 882.8k $17.7m | Added +63.6k |
| RA CAPITAL MANAGEMENT, L.P. 0.29% of their portfolio | 849.0k $17.0m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 816.2k $16.4m | Added +35.3k |
| 5AM Venture Management, LLC 5.96% of their portfolio | 772.5k $15.5m | Reduced -550.0k |
| Rock Springs Capital Management LP 0.88% of their portfolio | 701.4k $14.1m | Added +235.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 528.2k $10.6m | Added +512.1k |
| First Turn Management, LLC 1.91% of their portfolio | 510.0k $10.2m | Reduced -25.1k |
| TCG Crossover Management, LLC 1.14% of their portfolio | 498.0k $10.0m | New |
| Duquesne Family Office LLC 0.24% of their portfolio | 463.0k $9.3m | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 430.2k $8.6m | Added +410.0k |
| Candriam S.C.A. 0.05% of their portfolio | 416.6k $8.4m | New |
| Affinity Asset Advisors, LLC 1.19% of their portfolio | 400.0k $8.0m | New |
| Logos Global Management LP 0.94% of their portfolio | 350.0k $7.0m | Added +110.0k |
| MARSHALL WACE, LLP 0.01% of their portfolio | 333.3k $6.7m | Added +322.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 324.6k $6.5m | Reduced -14.0k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 318.4k $6.4m | Added +185.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 305.7k $6.1m | Added +46.1k |
| Ally Bridge Group (NY) LLC 4.94% of their portfolio | 281.4k $5.6m | Added +111.6k |
| MORGAN STANLEY 0.00% of their portfolio | 254.8k $5.1m | Added +173.5k |
| Vestal Point Capital, LP 0.26% of their portfolio | 250.0k $5.0m | New |
| Patient Square Capital LP 1.78% of their portfolio | 245.8k $4.9m | Reduced -8.0k |
| Cormorant Asset Management, LP 0.30% of their portfolio | 200.0k $4.0m | Reduced -50.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 189.5k $3.8m | Reduced -22.2k |
| HighVista Strategies LLC 1.04% of their portfolio | 141.5k $2.8m | Added +29.1k |
| UBS Group AG 0.00% of their portfolio | 138.3k $2.8m | Added +67.8k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 135.7k $2.7m | Added +130.6k |
| SPHERA FUNDS MANAGEMENT LTD. 0.67% of their portfolio | 128.5k $2.6m | Added +16.8k |
| BAKER BROS. ADVISORS LP 0.02% of their portfolio | 114.8k $2.3m | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 98.1k $2.0m | Added +4.6k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio | 96.0k $1.9m | Reduced -354.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 94.0k $1.9m | Added +9.3k |
| Nuveen, LLC 0.00% of their portfolio | 89.7k $1.8m | Reduced -14.4k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 83.1k $1.7m | Added +47.2k |
| BARCLAYS PLC 0.00% of their portfolio | 72.8k $1.5m | Added +22.4k |
| Susquehanna Portfolio Strategies, LLC 0.03% of their portfolio | 67.7k $1.4m | New |
| TD Asset Management Inc 0.00% of their portfolio | 66.9k $1.3m | New |
| Swiss National Bank 0.00% of their portfolio | 61.9k $1.2m | Added +20.0k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 59.2k $1.2m | Added +35.6k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 57.0k $1.1m | Added +27.6k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 56.8k $1.1m | Added +11.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 55.6k $1.1m | Added +10.7k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 50.3k $1.0m | Reduced -2.2k |
| Weiss Asset Management LP 0.02% of their portfolio | 47.6k $955.3k | Not comparable |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 46.9k $941.8k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 44.2k $885.7k | Added +31.3k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 36.8k $739.0k | Unchanged |
| SG Americas Securities, LLC 0.00% of their portfolio | 36.4k $730.0k | Added +23.3k |
| NEOS Investment Management LLC 0.01% of their portfolio | 32.6k $653.5k | Added +8.9k |
| Tema ETFs LLC 0.17% of their portfolio | 32.6k $653.5k | Added +8.9k |
| Legal & General Group Plc 0.00% of their portfolio | 32.2k $646.4k | Added +11.1k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 29.5k $592.7k | Reduced -76.0k |
| Aster Capital Management (DIFC) Ltd 0.13% of their portfolio | 28.6k $573.4k | New |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.02% of their portfolio | 28.3k $568.4k | Unchanged |
| Trexquant Investment LP 0.01% of their portfolio | 25.5k $512.1k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 24.5k $491.6k | Added +4.1k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 23.9k $479.4k | Added +12.0k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 22.5k $450.8k | Reduced -5.0k |
| Invesco Ltd. 0.00% of their portfolio | 22.0k $440.5k | Added +913 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 21.2k $425.5k | Reduced -258 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 20.3k $407.8k | Reduced -584 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 19.1k $382.4k | Reduced -2.7k |
| CITIGROUP INC 0.00% of their portfolio | 18.1k $363.9k | Reduced -12.7k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.00% of their portfolio | 17.7k $354.2k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 17.7k $354.2k | Reduced -4.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 16.7k $334.1k | Reduced -1.1k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 16.1k $322.9k | Reduced -53.0k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 14.5k $290.9k | Reduced -5.6k |
| CAXTON CORP 2.67% of their portfolio | 13.1k $262.7k | Not comparable |
| XTX Topco Ltd 0.01% of their portfolio | 11.4k $227.9k | Reduced -10.5k |
| Avidity Partners Management LP 0.05% of their portfolio | 11.3k $226.7k | Unchanged |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 10.5k $210.2k | Unchanged |
| SILVERARC CAPITAL MANAGEMENT, LLC 0.04% of their portfolio | 10.0k $200.6k | New |
| China Universal Asset Management Co., Ltd. 0.02% of their portfolio | 9.9k $197.7k | Added +55 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 9.8k $196.5k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 8.3k $166.5k | Unchanged |
| KLP KAPITALFORVALTNING AS 0.00% of their portfolio | 6.8k $136.4k | Added +2.5k |
| Point72 Asia (Singapore) Pte. Ltd. 0.02% of their portfolio | 6.6k $132.2k | Added +4.3k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 5.3k $106.0k | Added +3.5k |
| Virtus Investment Advisers, LLC 0.03% of their portfolio | 4.8k $95.9k | Reduced -2.4k |
| Quantbot Technologies LP 0.00% of their portfolio | 4.5k $89.8k | Added +1.4k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 3.7k $74.7k | Added +930 |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.4k $69.2k | Unchanged |
| BIT Capital GmbH 0.00% of their portfolio | 3.2k $63.8k | Reduced -16.2k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 1.9k $38.0k | Added +261 |