ORIC PHARMACEUTICALS INC ORIC
COM · Common Stock · CUSIP 68622P109
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($388.8k this quarter). Holder counts are more reliable. Shares outstanding: 97.1m as of 2025-08-05, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $10.15. Options: 5 managers hold calls ($10.5m notional), 2 hold puts ($102.5k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 77 |
| Q4 2022 | 65 |
| Q1 2023 | 72 |
| Q2 2023 | 84 |
| Q3 2023 | 92 |
| Q4 2023 | 93 |
| Q1 2024 | 113 |
| Q2 2024 | 114 |
| Q3 2024 | 123 |
| Q4 2024 | 130 |
| Q1 2025 | 144 |
| Q2 2025 | 143 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 43 | 37 |
| Q4 2023 | 54 | 39 |
| Q1 2024 | 66 | 43 |
| Q2 2024 | 74 | 38 |
| Q3 2024 | 58 | 52 |
| Q4 2024 | 67 | 46 |
| Q1 2025 | 81 | 53 |
| Q2 2025 | 77 | 86 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $155.2k | $8.2k | 0.05 |
| Q4 2024 | $3.3m | $51.6k | 0.02 |
| Q1 2025 | $74.0k | $25.1k | 0.34 |
| Q2 2025 | $10.5m | $102.5k | 0.01 |
Biggest buyers
| SR One Capital Management, LP | New | +4.5m |
| Venrock Adviser, LLC | Added | +3.4m |
| Point72 Asset Management, L.P. | New | +2.9m |
| NEA Management Company, LLC | Added | +1.9m |
| Nextech Invest Ltd. | Added | +1.9m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +1.4m |
| JPMORGAN CHASE & CO | Added | +1.3m |
| Integral Health Asset Management, LLC | New | +1.2m |
| Vivo Capital, LLC | Added | +1.0m |
| EVENTIDE ASSET MANAGEMENT, LLC | New | +951.4k |
Biggest sellers
| Commodore Capital LP | Sold out | -2.0m |
| EcoR1 Capital, LLC | Reduced | -1.8m |
| Boxer Capital Management, LLC | Sold out | -1.7m |
| BlackRock, Inc. | Reduced | -1.4m |
| STATE STREET CORP | Reduced | -564.4k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Sold out | -509.2k |
| SUPERSTRING CAPITAL MANAGEMENT LP | Reduced | -474.3k |
| Schonfeld Strategic Advisors LLC | Sold out | -426.9k |
| Frazier Life Sciences Management, L.P. | Reduced | -344.9k |
| SILVERARC CAPITAL MANAGEMENT, LLC | Reduced | -259.4k |
Biggest calls
| Caption Management, LLC | New | $10.1m996.2k shares |
| CITADEL ADVISORS LLC | Added | $222.3k21.9k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $141.1k13.9k shares |
| SIMPLEX TRADING, LLC | Added | $33.0k3.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $102.5k10.1k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Nextech Crossover I GP S.a r.l. 13G · passive investor filed 2025-08-14 | 8.4% |
| VIKING GLOBAL INVESTORS LP 13G · passive investor -2.2 pts · filed 2026-05-15 | 7.8% |
| EcoR1 Capital, LLC 13G · institution new · filed 2025-08-05 | 6.9% |
| BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-01-21 | 5.6% |
| PRICE T ROWE ASSOCIATES INC /MD/ 13G · institution new · filed 2026-05-15 | 5.4% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), Venrock Healthcare Capital Partners III, L.P. (4.2%, 2026-05-15), PFIZER INC (3.3%, 2026-05-12), COLUMN GROUP II, LP (3.7%, 2025-11-17), ALKEON CAPITAL MANAGEMENT LLC (4.6%, 2025-11-13)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 1 | $160.2k | — |
| Q4 2023 | 0 | — | 3 | $215.4k | — |
| Q1 2024 | 0 | — | 1 | $1.1m | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 3 | $350.7k | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 1 | $263.0k | 1 | $416.3k | $416.3k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-06-24 | Piscitelli Dominic Chief Financial Officer | Sold plan | $340.9k32.5k shares |
| 2025-06-23 | You Angie Director | Bought | $13.2k1.4k shares |
| 2025-06-23 | Piscitelli Dominic Chief Financial Officer | Sold plan | $10.3k1.0k shares |
| 2025-06-20 | You Angie Director | Bought | $249.7k26.6k shares |
| 2025-06-12 | Piscitelli Dominic Chief Financial Officer | Sold plan | $3.0k300 shares |
| 2025-06-11 | Piscitelli Dominic Chief Financial Officer | Sold plan | $29.8k3.0k shares |
| 2025-06-10 | Piscitelli Dominic Chief Financial Officer | Sold plan | $3.2k324 shares |
| 2025-06-09 | Piscitelli Dominic Chief Financial Officer | Sold plan | $3.0k300 shares |
| 2025-06-06 | Piscitelli Dominic Chief Financial Officer | Sold plan | $26.0k2.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| Nextech Invest Ltd. 13.76% of their portfolio | 7.2m $72.7m | Added +1.9m |
| Venrock Adviser, LLC 5.02% of their portfolio | 6.6m $67.0m | Added +3.4m |
| VIKING GLOBAL INVESTORS LP 0.19% of their portfolio | 6.6m $66.7m | Unchanged |
| Pfizer Inc 9.47% of their portfolio | 5.4m $54.6m | Unchanged |
| SR One Capital Management, LP 9.93% of their portfolio | 4.5m $45.8m | New |
| ALKEON CAPITAL MANAGEMENT LLC 0.22% of their portfolio | 4.5m $45.7m | Added +500.0k |
| NEA Management Company, LLC 3.15% of their portfolio | 4.1m $41.8m | Added +1.9m |
| BlackRock, Inc. 0.00% of their portfolio | 4.1m $41.4m | Reduced -1.4m |
| Column Group LLC 54.68% of their portfolio | 3.5m $35.9m | Unchanged |
| Vivo Capital, LLC 3.25% of their portfolio | 3.1m $31.7m | Added +1.0m |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.1m $31.7m | Reduced -91.2k |
| Point72 Asset Management, L.P. 0.07% of their portfolio | 2.9m $28.9m | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 2.8m $28.0m | Added +1.4m |
| FMR LLC 0.00% of their portfolio | 2.5m $25.1m | Reduced -10.4k |
| First Turn Management, LLC 3.81% of their portfolio | 2.0m $20.4m | Reduced -17.5k |
| SILVERARC CAPITAL MANAGEMENT, LLC 3.74% of their portfolio | 1.8m $18.3m | Reduced -259.4k |
| Balyasny Asset Management L.P. 0.04% of their portfolio | 1.8m $18.0m | Reduced -229.5k |
| MPM BIOIMPACT LLC 3.04% of their portfolio | 1.7m $17.6m | Added +329.9k |
| STATE STREET CORP 0.00% of their portfolio | 1.6m $16.6m | Reduced -564.4k |
| EcoR1 Capital, LLC 0.97% of their portfolio | 1.6m $16.4m | Reduced -1.8m |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 1.4m $14.2m | Added +890.9k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.3m $13.6m | Added +1.3m |
| ArrowMark Colorado Holdings LLC 0.23% of their portfolio | 1.3m $13.0m | Reduced -67.7k |
| Integral Health Asset Management, LLC 1.19% of their portfolio | 1.2m $12.7m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.1m $11.3m | Reduced -197.5k |
| Frazier Life Sciences Management, L.P. 0.43% of their portfolio | 1.1m $10.8m | Reduced -344.9k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 1.0m $10.6m | Added +19.8k |
| Siren, L.L.C. 0.53% of their portfolio | 1.0m $10.2m | Unchanged |
| Euclidean Capital LLC 3.28% of their portfolio | 989.4k $10.0m | Unchanged |
| EVENTIDE ASSET MANAGEMENT, LLC 0.17% of their portfolio | 951.4k $9.7m | New |
| ORBIMED ADVISORS LLC 0.23% of their portfolio | 899.3k $9.1m | Added +199.3k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 714.9k $7.3m | Reduced -13.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 489.6k $5.0m | Added +194.9k |
| Ally Bridge Group (NY) LLC 4.31% of their portfolio | 485.6k $4.9m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 401.0k $4.1m | Reduced -145.8k |
| MORGAN STANLEY 0.00% of their portfolio | 394.8k $4.0m | Added +226.1k |
| SPHERA FUNDS MANAGEMENT LTD. 1.05% of their portfolio | 394.7k $4.0m | Added +159.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 382.4k $3.9m | Reduced -26.1k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 365.4k $3.7m | New |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 350.5k $3.6m | Added +296.6k |
| SUPERSTRING CAPITAL MANAGEMENT LP 4.36% of their portfolio | 344.9k $3.5m | Reduced -474.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 298.4k $3.0m | Added +38.6k |
| Atom Investors LP 0.23% of their portfolio | 252.7k $2.6m | Added +41.9k |
| Woodline Partners LP 0.01% of their portfolio | 244.4k $2.5m | New |
| ROYCE & ASSOCIATES LP 0.02% of their portfolio | 234.8k $2.4m | New |
| SECTORAL ASSET MANAGEMENT INC 1.55% of their portfolio | 231.5k $2.3m | Added +211.5k |
| Resolute Capital Asset Partners LLC 1.21% of their portfolio | 227.5k $2.3m | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 223.3k $2.3m | Added +45.1k |
| STEMPOINT CAPITAL LP 0.66% of their portfolio | 200.8k $2.0m | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 199.8k $2.0m | Added +195.0k |
| TD Asset Management Inc 0.00% of their portfolio | 177.7k $1.8m | Added +25.0k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 171.4k $1.7m | Added +121.9k |
| Hennion & Walsh Asset Management, Inc. 0.06% of their portfolio | 149.7k $1.5m | Reduced -6.9k |
| BARCLAYS PLC 0.00% of their portfolio | 142.7k $1.4m | Added +40.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 141.0k $1.4m | Added +14.3k |
| DAFNA Capital Management LLC 0.38% of their portfolio | 135.3k $1.4m | Reduced -106.7k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 135.0k $1.4m | Reduced -31.1k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 132.6k $1.3m | Reduced -17.6k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 124.1k $1.3m | Reduced -5.5k |
| Nuveen, LLC 0.00% of their portfolio | 122.7k $1.2m | Reduced -44.8k |
| Squarepoint Ops LLC 0.00% of their portfolio | 106.8k $1.1m | New |
| HRT FINANCIAL LP 0.01% of their portfolio | 102.6k $1.0m | New |
| UBS Group AG 0.00% of their portfolio | 99.0k $1.0m | Added +19.5k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 91.2k $925.8k | Reduced -21.4k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 86.8k $880.6k | Added +79.5k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 76.4k $775.9k | New |
| FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio | 76.3k $774.3k | Reduced -102.4k |
| Nicholas Investment Partners, LP 0.07% of their portfolio | 74.2k $753.6k | Reduced -80.1k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 71.4k $725.0k | Reduced -17.3k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 63.8k $647.7k | Reduced -43.6k |
| Invesco Ltd. 0.00% of their portfolio | 61.6k $624.9k | Added +21.1k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.01% of their portfolio | 49.0k $497.4k | Added +1.4k |
| Palumbo Wealth Management LLC 0.15% of their portfolio | 46.8k $474.8k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 46.7k $474.1k | Added +15.5k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio | 43.4k $440.4k | Reduced -25.6k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 42.6k $432.8k | Reduced -34.8k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 38.9k $394.5k | Added +2.7k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 38.6k $391.6k | Reduced -13.4k |
| LMR Partners LLP 0.01% of their portfolio | 35.3k $358.0k | Reduced -33 |
| Brevan Howard Capital Management LP 0.00% of their portfolio | 34.7k $352.5k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 33.6k $341.1k | Reduced -5.4k |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 33.5k $340.3k | Reduced -1.8k |
| CITIGROUP INC 0.00% of their portfolio | 32.5k $330.4k | Reduced -71.6k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 27.1k $274.8k | Reduced -13.8k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 26.7k $270.9k | Reduced -13.5k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 25.9k $262.6k | Reduced -14.9k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 25.4k $258.3k | Reduced -15.3k |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 23.0k $233.3k | New |
| Brooklyn Investment Group 0.03% of their portfolio | 20.9k $212.2k | New |
| Point72 Asia (Singapore) Pte. Ltd. 0.04% of their portfolio | 20.9k $212.1k | New |
| Jasper Ridge Partners, L.P. 0.01% of their portfolio | 20.9k $211.8k | Unchanged |
| AlphaQuest LLC 0.02% of their portfolio | 20.2k $204.6k | Reduced -22.5k |
| Monaco Asset Management SAM 0.08% of their portfolio | 20.0k $203.0k | New |
| Campbell & CO Investment Adviser LLC 0.01% of their portfolio | 19.7k $199.6k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 17.8k $180.6k | Reduced -20.7k |
| Clear Harbor Asset Management, LLC 0.01% of their portfolio | 15.1k $153.5k | Unchanged |
| TWO SIGMA SECURITIES, LLC 0.02% of their portfolio | 14.3k $145.5k | New |
| Sanctuary Advisors, LLC 0.00% of their portfolio | 14.3k $145.0k | New |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 14.3k $144.9k | Added +31 |
| AXQ CAPITAL, LP 0.04% of their portfolio | 12.9k $131.4k | Added +2.9k |