SURROZEN INC SRZN
COM NEW · Common Stock · CUSIP 86889P208
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 8.6m as of 2025-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $8.94.
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q4 2023 | 17 |
| Q1 2024 | 16 |
| Q2 2024 | 21 |
| Q3 2024 | 23 |
| Q4 2024 | 24 |
| Q1 2025 | 30 |
| Q2 2025 | 31 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 6 | 4 |
| Q2 2024 | 12 | 6 |
| Q3 2024 | 8 | 7 |
| Q4 2024 | 8 | 9 |
| Q1 2025 | 17 | 3 |
| Q2 2025 | 12 | 5 |
Biggest buyers
| STEMPOINT CAPITAL LP | Added | +445.7k |
| VANGUARD GROUP INC | Added | +150.9k |
| BRAIDWELL LP | New | +140.0k |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA | Added | +133.2k |
| ARMISTICE CAPITAL, LLC | New | +60.0k |
| Stonepine Capital Management, LLC | Added | +20.2k |
| CITADEL ADVISORS LLC | New | +10.5k |
| BlackRock, Inc. | Added | +7.2k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +5.7k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +400 |
Biggest sellers
| Driehaus Capital Management LLC | Reduced | -137.4k |
| RA CAPITAL MANAGEMENT, L.P. | Reduced | -76.5k |
| HEIGHTS CAPITAL MANAGEMENT, INC | Sold out | -45.0k |
| Tower Research Capital LLC (TRC) | Reduced | -186 |
| JPMORGAN CHASE & CO | Sold out | -5 |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
COLUMN GROUP III GP, LP
13D · may seek influence
-7.8 pts · filed 2026-10-22
Stated purposeThe information set forth in Item 4 of the Original Schedule 13D is incorporated herein by reference. Full filing |
21.5% |
| Boxer Capital Management, LLC 13G · institution +2.7 pts · filed 2026-10-07 | 11.6% |
Column Group IV GP, LP
13D · may seek influence
new · filed 2026-02-12
Stated purposeThe information set forth in Item 3 of this Statement is incorporated herein by reference. The Reporting Persons hold the securities of the Issuer for general investment purposes. The Reporting Persons may, from time to time, depending on prevailing market, economic and other conditions, acquire additional shares of Common Stock or other securities of the Issuer, dispose of any such securities, or engage in discussions with the Issuer concerning such acquisitions or dispositions or further investments in the Issuer. The Reporting Persons intend to review their investment in the Issuer on a continuing basis and, depending upon the price and availability of shares of Common Stock or other securities of the Issuer, subsequent developments affecting the Issuer, the Issuer's business and prospe… Full filing |
11.6% |
| TCG Crossover GP II, LLC 13G · passive investor -2.8 pts · filed 2026-07-24 | 9.9% |
| Venrock Healthcare Capital Partners III, L.P. 13G · passive investor no change · filed 2026-05-15 | 9.9% |
| AI Biotechnology LLC 13G · passive investor new · filed 2025-03-31 | 9.9% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor -0.7 pts · filed 2026-02-17 | 9.2% |
| INTEGRATED CORE STRATEGIES (US) LLC 13G · passive investor +1.9 pts · filed 2026-02-05 | 8.5% |
| 5AM Partners VII, LLC 13G · passive investor -1.7 pts · filed 2026-08-11 | 7.8% |
| Commodore Capital LP 13G · passive investor new · filed 2026-10-01 | 7.5% |
| Point72 Asset Management, L.P. 13G · passive investor new · filed 2026-04-23 | 5.4% |
| STEMPOINT CAPITAL LP 13G · institution +0.5 pts · filed 2026-08-14 | 5.0% |
Fell to 5% or below in the last year: BRAIDWELL LP (3.9%, 2026-08-14), Nantahala Capital Management, LLC (2.1%, 2026-05-15), Stonepine Capital Management, LLC (3.6%, 2026-02-13)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 3 | $3.0m | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 2 | $35.2k | — |
| Q2 2025 | 0 | — | 0 | — | — |
None reported in Q2 2025.
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| STEMPOINT CAPITAL LP 1.98% of their portfolio | 686.5k $6.1m | Added +445.7k |
| Venrock Adviser, LLC 0.42% of their portfolio | 632.9k $5.7m | Unchanged |
| RA CAPITAL MANAGEMENT, L.P. 0.09% of their portfolio | 602.6k $5.4m | Reduced -76.5k |
| 5AM Venture Management, LLC 1.07% of their portfolio | 310.0k $2.8m | Unchanged |
| Stonepine Capital Management, LLC 2.70% of their portfolio | 306.0k $2.7m | Added +20.2k |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA 0.14% of their portfolio | 266.4k $2.4m | Added +133.2k |
| Vivo Capital, LLC 0.24% of their portfolio | 260.0k $2.3m | Unchanged |
| SAMSARA BIOCAPITAL, LLC 0.44% of their portfolio | 241.4k $2.2m | Unchanged |
| Nantahala Capital Management, LLC 0.15% of their portfolio | 229.5k $2.1m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 218.9k $2.0m | Added +150.9k |
| ACUTA CAPITAL PARTNERS, LLC 2.12% of their portfolio | 170.0k $1.5m | Unchanged |
| BRAIDWELL LP 0.04% of their portfolio | 140.0k $1.3m | New |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio | 88.7k $792.6k | Unchanged |
| Euclidean Capital LLC 0.26% of their portfolio | 87.7k $784.0k | Unchanged |
| Driehaus Capital Management LLC 0.00% of their portfolio | 67.6k $604.0k | Reduced -137.4k |
| ARMISTICE CAPITAL, LLC 0.02% of their portfolio | 60.0k $536.4k | New |
| ArrowMark Colorado Holdings LLC 0.01% of their portfolio | 55.1k $492.8k | Unchanged |
| Board of Trustees of The Leland Stanford Junior University 0.05% of their portfolio | 52.1k $466.0k | Unchanged |
| Trustees of Columbia University in the City of New York 0.06% of their portfolio | 47.9k $428.5k | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 34.8k $310.8k | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 31.0k $276.9k | Added +5.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 21.7k $195.0k | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 15.5k $138.4k | Added +7.2k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 14.6k $130.8k | Added +400 |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 10.5k $93.4k | New |
| Alyeska Investment Group, L.P. 0.00% of their portfolio | 10.2k $91.1k | Unchanged |
| WOLVERINE ASSET MANAGEMENT LLC 0.00% of their portfolio | 281 $2.5k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 259 $2.3k | Added +62 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 216 $1.9k | Reduced -186 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 52 $465 | Added +36 |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. — of their portfolio | 0 $0 | Unchanged |