Vault-13

KALVISTA PHARMACEUTICALS INC KALV

COM · Common Stock · CUSIP 483497103

141 institutional holders +12 vs Q1 2025
54,498,54054.5m shares reported held*
$616.1mreported value*
29 new 54 added 33 reduced 17 sold out net sold ≈ $5.1m (-420.5k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($132.0k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $11.30. Options: 9 managers hold calls ($12.4m notional), 4 hold puts ($1.0m).

Trends to Q2 2025

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 94Q4 22: 91Q1 23: 90Q2 23: 96Q3 23: 102Q4 23: 94Q1 24: 130Q2 24: 120Q3 24: 123Q4 24: 131Q1 25: 129Q2 25: 141141Q3 22Q2 23Q1 24Q4 24Q2 25
Numbers
QuarterHolders
Q3 202294
Q4 202291
Q1 202390
Q2 202396
Q3 2023102
Q4 202394
Q1 2024130
Q2 2024120
Q3 2024123
Q4 2024131
Q1 2025129
Q2 2025141

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q3 23: 52 bought or addedQ3 23: 38 cut or sold outQ4 23: 54 bought or addedQ4 23: 44 cut or sold outQ4 23Q1 24: 79 bought or addedQ1 24: 45 cut or sold outQ2 24: 61 bought or addedQ2 24: 61 cut or sold outQ2 24Q3 24: 65 bought or addedQ3 24: 44 cut or sold outQ4 24: 69 bought or addedQ4 24: 48 cut or sold outQ4 24Q1 25: 67 bought or addedQ1 25: 57 cut or sold outQ2 25: 83 bought or addedQ2 25: 50 cut or sold outQ2 25
Numbers
QuarterBought or addedCut or sold out
Q3 20235238
Q4 20235444
Q1 20247945
Q2 20246161
Q3 20246544
Q4 20246948
Q1 20256757
Q2 20258350

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$5m$10m$15m$20mQ3 24 calls: $5.8mQ3 24 puts: $1.4mQ3 24P/C 0.23Q4 24 calls: $115.2kQ4 24 puts: $1.8mQ4 24P/C 15.64Q1 25 calls: $15.8mQ1 25 puts: $69.2kQ1 25P/C 0.00Q2 25 calls: $12.4mQ2 25 puts: $1.0mQ2 25P/C 0.08
Numbers
QuarterCallsPutsP/C
Q3 2024$5.8m$1.4m0.23
Q4 2024$115.2k$1.8m15.64
Q1 2025$15.8m$69.2k0.00
Q2 2025$12.4m$1.0m0.08

Biggest buyers

AMERIPRISE FINANCIAL INC Added +905,053+905.1k
Woodline Partners LP Added +303,195+303.2k
STATE STREET CORP Added +255,896+255.9k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added +242,030+242.0k
PANAGORA ASSET MANAGEMENT INC Added +220,697+220.7k
First Turn Management, LLC New +214,138+214.1k
Ikarian Capital, LLC New +198,528+198.5k
EMERALD MUTUAL FUND ADVISERS TRUST Added +160,759+160.8k
NAN FUNG TRINITY (HK) LTD New +154,522+154.5k
CITIGROUP INC Added +150,967+151.0k

Biggest sellers

GREAT POINT PARTNERS LLC Reduced -691,197-691.2k
DIMENSIONAL FUND ADVISORS LP Reduced -472,784-472.8k
Schonfeld Strategic Advisors LLC Reduced -436,464-436.5k
Allostery Investments LP Reduced -418,302-418.3k
JPMORGAN CHASE & CO Reduced -379,286-379.3k
Jefferies Financial Group Inc. Sold out -375,000-375.0k
SCHRODER INVESTMENT MANAGEMENT GROUP Reduced -313,053-313.1k
ADAGE CAPITAL PARTNERS GP, L.L.C. Sold out -276,000-276.0k
Walleye Capital LLC Sold out -249,161-249.2k
UBS Group AG Reduced -234,842-234.8k

Biggest calls

Ikarian Capital, LLC New $4.5m400.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $3.1m270.6k shares
BOOTHBAY FUND MANAGEMENT, LLC New $1.6m142.9k shares
JANE STREET GROUP, LLC Added $1.5m129.9k shares
SIMPLEX TRADING, LLC Reduced $889.0k78.7k shares
BARCLAYS PLC New $574.3k50.8k shares
Walleye Capital LLC New $241.9k21.4k shares
GROUP ONE TRADING LLC Reduced $27.1k2.4k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

MILLENNIUM MANAGEMENT LLC New $1.0m90.0k shares
SIMPLEX TRADING, LLC New $22.0k2.0k shares
Walleye Capital LLC New $1.1k100 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Capital World Investors 13G · institution filed 2025-05-13 6.4% 3.2m 2025-05-13
SILVERARC CAPITAL MANAGEMENT, LLC 13G · institution new · filed 2026-05-13 5.6% new 2.9m 2026-05-13

Fell to 5% or below in the last year: TANG CAPITAL MANAGEMENT LLC (0.0%, 2026-08-14), GLAZER CAPITAL, LLC (4.8%, 2026-06-10), Frazier Life Sciences Public Fund, L.P. (2.3%, 2026-05-21), Point72 Asset Management, L.P. (4.2%, 2026-05-15), MILLENNIUM MANAGEMENT LLC (3.7%, 2026-05-01), Vestal Point Capital, LP (1.5%, 2025-11-14)

Holders, Q2 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Venrock Adviser, LLC 5.70% of their portfolio NEW YORK, NY 6,728,9856.7m $76.1m $76.1m 5.70% Added +25.0k +25,000
2 MONTANOVA CAPITAL, LLC 2.11% of their portfolio New York, NY 4,955,0005.0m $56.0m $56.0m 2.11% Added +42.0k +41,988
3 TANG CAPITAL MANAGEMENT LLC 2.82% of their portfolio SAN DIEGO, CA 4,941,7984.9m $55.9m $55.9m 2.82% Unchanged
4 Frazier Life Sciences Management, L.P. 2.21% of their portfolio PALO ALTO, CA 4,887,8674.9m $55.3m $55.3m 2.21% Unchanged
5 Vestal Point Capital, LP 2.78% of their portfolio NEW YORK, NY 4,675,0004.7m $52.9m $52.9m 2.78% Reduced -76.3k -76,292
6 Capital World Investors 0.01% of their portfolio LOS ANGELES, CA 3,177,5873.2m $35.9m $35.9m 0.01% Unchanged
7 BlackRock, Inc. 0.00% of their portfolio New York, NY 3,129,4943.1m $35.4m $35.4m 0.00% Reduced -22.2k -22,241
8 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 2,412,3992.4m $27.3m $27.3m 0.00% Added +113.8k +113,801
9 Woodline Partners LP 0.11% of their portfolio San Francisco, CA 1,920,6641.9m $21.7m $21.7m 0.11% Added +303.2k +303,195
10 SILVERARC CAPITAL MANAGEMENT, LLC 4.24% of their portfolio BOSTON, MA 1,832,1711.8m $20.7m $20.7m 4.24% Added +133.2k +133,187
11 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,349,5391.3m $15.3m $15.3m 0.00% Added +255.9k +255,896
12 Octagon Capital Advisors LP 3.16% of their portfolio NEW YORK, NY 1,273,3331.3m $14.4m $14.4m 3.16% Reduced -96.7k -96,667
13 EMERALD ADVISERS, LLC 0.43% of their portfolio LEOLA, PA 1,038,0491.0m $11.7m $11.7m 0.43% Added +139.9k +139,859
14 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 945,125945.1k $10.7m $10.7m 0.00% Added +905.1k +905,053
15 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 941,212941.2k $10.6m $10.6m 0.00% Added +26.0k +25,971
16 EMERALD MUTUAL FUND ADVISERS TRUST 0.53% of their portfolio LEOLA, PA 768,972769.0k $8.7m $8.7m 0.53% Added +160.8k +160,759
17 Parkman Healthcare Partners LLC 0.89% of their portfolio STAMFORD, CT 679,063679.1k $7.7m $7.7m 0.89% Reduced -74.7k -74,689
18 DAFNA Capital Management LLC 1.82% of their portfolio LOS ANGELES, CA 581,757581.8k $6.6m $6.6m 1.82% Reduced -170.6k -170,602
19 SCHRODER INVESTMENT MANAGEMENT GROUP 0.01% of their portfolio London, X0 554,958555.0k $6.3m $6.3m 0.01% Reduced -313.1k -313,053
20 STEMPOINT CAPITAL LP 1.41% of their portfolio NEW YORK, NY 386,790386.8k $4.4m $4.4m 1.41% Reduced -47 -47
21 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 366,966367.0k $4.1m $4.1m 0.00% Added +58.7k +58,719
22 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 352,152352.2k $4.0m $4.0m 0.00% Reduced -35.4k -35,410
23 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 340,629340.6k $3.9m $3.9m 0.00% Added +142.4k +142,424
24 GREAT POINT PARTNERS LLC 2.38% of their portfolio Greenwich, CT 323,170323.2k $3.7m $3.7m 2.38% Reduced -691.2k -691,197
25 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 299,194299.2k $3.4m $3.4m 0.00% Added +151.0k +150,967
26 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio BALA CYNWYD, PA 294,198294.2k $3.3m $3.3m 0.01% Added +242.0k +242,030
27 PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio BOSTON, MA 292,593292.6k $3.3m $3.3m 0.01% Added +220.7k +220,697
28 UBS Group AG 0.00% of their portfolio ZURICH, V8 272,861272.9k $3.1m $3.1m 0.00% Reduced -234.8k -234,842
29 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 239,629239.6k $2.7m $2.7m 0.00% Added +15.8k +15,840
30 First Turn Management, LLC 0.45% of their portfolio DEL MAR, CA 214,138214.1k $2.4m $2.4m 0.45% New
31 Ikarian Capital, LLC 0.74% of their portfolio DALLAS, TX 198,528198.5k $2.2m $2.2m 0.74% New
32 F/m Investments LLC 0.07% of their portfolio WASHINGTON, DC 182,262182.3k $2.1m $2.1m 0.07% Added +132.2k +132,165
33 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 173,209173.2k $2.0m $2.0m 0.00% Reduced -472.8k -472,784
34 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 168,923168.9k $1.9m $1.9m 0.00% Added +113.7k +113,696
35 Rosalind Advisors, Inc. 0.86% of their portfolio TORONTO, A6 157,725157.7k $1.8m $1.8m 0.86% Reduced -146.1k -146,139
36 Hennion & Walsh Asset Management, Inc. 0.07% of their portfolio Parsippany, NJ 155,961156.0k $1.8m $1.8m 0.07% Added +44.9k +44,855
37 NAN FUNG TRINITY (HK) LTD 0.21% of their portfolio CENTRAL, HONG KONG, K3 154,522154.5k $1.7m $1.7m 0.21% New
38 BOOTHBAY FUND MANAGEMENT, LLC 0.05% of their portfolio NEW YORK, NY 148,927148.9k $1.7m $1.7m 0.05% New
39 Schonfeld Strategic Advisors LLC 0.01% of their portfolio NEW YORK, NY 145,282145.3k $1.6m $1.6m 0.01% Reduced -436.5k -436,464
40 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 134,398134.4k $1.5m $1.5m 0.00% Reduced -205.5k -205,538
41 FMR LLC 0.00% of their portfolio BOSTON, MA 133,566133.6k $1.5m $1.5m 0.00% Added +50.7k +50,670
42 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 132,900132.9k $1.5m $1.5m 0.00% Added +6.6k +6,632
43 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 128,588128.6k $1.5m $1.5m 0.00% Added +128.4k +128,437
44 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 119,622119.6k $1.4m $1.4m 0.00% Added +38.7k +38,657
45 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 113,496113.5k $1.3m $1.3m 0.00% Added +372 +372
46 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 107,635107.6k $1.2m $1.2m 0.00% Added +4.1k +4,105
47 RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio ST. PETERSBURG, FL 101,035101.0k $1.1m $1.1m 0.00% New
48 Stonepine Capital Management, LLC 1.11% of their portfolio Bend, OR 100,000100.0k $1.1m $1.1m 1.11% Added +78.5k +78,450
49 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 97,24897.2k $1.1m $1.1m 0.00% New
50 Boxer Capital Management, LLC 0.53% of their portfolio San Diego, CA 93,40093.4k $1.1m $1.1m 0.53% New
51 Susquehanna Portfolio Strategies, LLC 0.02% of their portfolio Bala Cynwyd, PA 92,25992.3k $1.0m $1.0m 0.02% New
52 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% of their portfolio CHICAGO, IL 79,46079.5k $898.3k $898.3k 0.02% Reduced -90.2k -90,232
53 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 73,34373.3k $829.1k $829.1k 0.00% Added +12.3k +12,300
54 Nuveen, LLC 0.00% of their portfolio CHARLOTTE, NC 68,53968.5k $774.8k $774.8k 0.00% Added +31.2k +31,218
55 Birchview Capital, LP 0.75% of their portfolio BURLINGTON, VT 67,00067.0k $757.4k $757.4k 0.75% Reduced -2 -2
56 Saturn V Capital Management LP 0.29% of their portfolio AUSTIN, TX 62,79362.8k $709.9k $709.9k 0.29% Reduced -192.3k -192,267
57 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 54,91054.9k $620.8k $620.8k 0.00% New
58 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 54,37654.4k $614.7k $614.7k 0.00% Added +1.5k +1,458
59 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 53,06953.1k $599.9k $599.9k 0.00% Added +41 +41
60 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 50,76150.8k $573.9k $573.9k 0.00% Added +11.0k +10,957
61 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 47,41347.4k $536.0k $536.0k 0.00% Reduced -8.6k -8,562
62 Rafferty Asset Management, LLC 0.00% of their portfolio New York, NY 46,90146.9k $530.2k $530.2k 0.00% Added +20.6k +20,632
63 Skandinaviska Enskilda Banken AB (publ) 0.00% of their portfolio STOCKHOLM, V7 40,86340.9k $462.2k $462.2k 0.00% Unchanged
64 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 40,02040.0k $452.4k $452.4k 0.00% Unchanged
65 Allostery Investments LP 5.76% of their portfolio Stamford, CT 40,00040.0k $452.2k $452.2k 5.76% Reduced -418.3k -418,302
66 OMERS ADMINISTRATION Corp 0.00% of their portfolio TORONTO, A6 33,90033.9k $383.2k $383.2k 0.00% New
67 Creative Planning 0.00% of their portfolio OVERLAND PARK, KS 33,38033.4k $377.4k $377.4k 0.00% Added +5.6k +5,573
68 EVOKE WEALTH, LLC 0.01% of their portfolio Los Angeles, CA 32,18132.2k $363.8k $363.8k 0.01% Reduced -265 -265
69 Virtu Financial LLC 0.02% of their portfolio New York, NY 30,73930.7k $347.0k $347.0k 0.02% New
70 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio BALA CYNWYD, PA 28,88428.9k $326.5k $326.5k 0.01% Reduced -14.3k -14,259
71 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 28,47428.5k $322.0k $322.0k 0.00% Reduced -3.7k -3,652
72 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 26,38626.4k $298.3k $298.3k 0.00% New
73 Engineers Gate Manager LP 0.00% of their portfolio NEW YORK, NY 26,25726.3k $296.8k $296.8k 0.00% Added +415 +415
74 D. E. Shaw & Co., Inc. 0.00% of their portfolio New York, NY 25,72025.7k $290.8k $290.8k 0.00% Unchanged
75 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 25,32425.3k $286.3k $286.3k 0.00% Added +2.5k +2,462
76 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 23,21823.2k $262.5k $262.5k 0.00% Reduced -379.3k -379,286
77 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 22,96423.0k $259.8k $259.8k 0.00% Reduced -1.4k -1,361
78 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 21,91521.9k $247.6k $247.6k 0.00% New
79 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 21,68821.7k $245.2k $245.2k 0.00% Unchanged
80 Quadrature Capital Ltd 0.00% of their portfolio LONDON, X0 19,97320.0k $225.9k $225.9k 0.00% New
81 Rathbones Group PLC 0.00% of their portfolio Liverpool, X0 19,02219.0k $215.0k $215.0k 0.00% Unchanged
82 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 17,86417.9k $202.0k $202.0k 0.00% Added +1.0k +1,041
83 INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio WEST PALM BEACH, FL 17,67117.7k $199.8k $199.8k 0.00% Reduced -217 -217
84 Quarry LP 0.04% of their portfolio NEW YORK, NY 16,79616.8k $189.9k $189.9k 0.04% Added +8.4k +8,396
85 IRONWOOD INVESTMENT MANAGEMENT LLC 0.09% of their portfolio BOSTON, MA 16,71116.7k $188.9k $188.9k 0.09% Added +5.2k +5,223
86 Atom Investors LP 0.02% of their portfolio AUSTIN, TX 16,31216.3k $184.4k $184.4k 0.02% New
87 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 15,84115.8k $179.1k $179.1k 0.00% New
88 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 14,62614.6k $165.3k $165.3k 0.00% Added +818 +818
89 Brevan Howard Capital Management LP 0.00% of their portfolio ST. HELIER, Y9 13,33313.3k $150.7k $150.7k 0.00% New
90 Trexquant Investment LP 0.00% of their portfolio STAMFORD, CT 12,78112.8k $144.5k $144.5k 0.00% New
91 Whalen Wealth Management Inc. 0.08% of their portfolio LAS VEGAS, NV 10,93810.9k $123.7k $123.7k 0.08% New
92 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 10,71410.7k $121.1k $121.1k 0.00% Reduced -9.8k -9,764
93 Martin Worley Group 0.06% of their portfolio COTTONWOOD HEIGHTS, UT 10,16810.2k $114.9k $114.9k 0.06% Unchanged
94 PROFUND ADVISORS LLC 0.00% of their portfolio BETHESDA, MD 10,02010.0k $113.3k $113.3k 0.00% New
95 Choate Investment Advisors 0.00% of their portfolio BOSTON, MA 10,00010.0k $113.0k $113.0k 0.00% Unchanged
96 ADAR1 Capital Management, LLC 0.02% of their portfolio AUSTIN, TX 10,00010.0k $113.0k $113.0k 0.02% Reduced -25.7k -25,743
97 China Universal Asset Management Co., Ltd. 0.01% of their portfolio SHANGHAI, F4 9,98510.0k $112.9k $112.9k 0.01% Added +73 +73
98 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 9,96410.0k $112.6k $112.6k 0.00% Unchanged
99 Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio TRENTON, NJ 9,7569.8k $110.3k $110.3k 0.00% Added +2.1k +2,061
100 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 8,0598.1k $91.1k $91.1k 0.00% Added +7.2k +7,180