CASI PHARMACEUTICALS INC CASIF
ORD SHS · Common Stock · CUSIP G1933S101
- SectorHealth care
- IndustryPharmaceutical Preparations
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $1.18. Options: 1 managers hold calls ($0 notional), 2 hold puts ($0).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q4 2022 | 1 |
| Q1 2023 | 21 |
| Q2 2023 | 20 |
| Q3 2023 | 20 |
| Q4 2023 | 19 |
| Q1 2024 | 21 |
| Q2 2024 | 24 |
| Q3 2024 | 21 |
| Q4 2024 | 23 |
| Q1 2025 | 24 |
| Q2 2025 | 25 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 5 | 9 |
| Q4 2023 | 6 | 9 |
| Q1 2024 | 10 | 5 |
| Q2 2024 | 9 | 9 |
| Q3 2024 | 6 | 7 |
| Q4 2024 | 4 | 9 |
| Q1 2025 | 8 | 4 |
| Q2 2025 | 7 | 10 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $2.4k | $8.3k | 3.50 |
| Q4 2024 | $0 | $0 | — |
| Q1 2025 | $0 | $0 | — |
| Q2 2025 | $0 | $0 | — |
Biggest buyers
| CITADEL ADVISORS LLC | New | +36.2k |
| BANK OF AMERICA CORP /DE/ | Added | +12.0k |
| TWO SIGMA SECURITIES, LLC | New | +11.6k |
| ROYAL BANK OF CANADA | Added | +10.2k |
| Woodline Partners LP | Added | +1.3k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +300 |
| CITIGROUP INC | New | +19 |
Biggest sellers
| Foresite Capital Management VI LLC | Reduced | -542.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -11.0k |
| ADAR1 Capital Management, LLC | Reduced | -3.3k |
| UBS Group AG | Reduced | -2.1k |
| MORGAN STANLEY | Reduced | -1.1k |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | -555 |
| WEST PACES ADVISORS INC. | Sold out | -100 |
| SIMPLEX TRADING, LLC | Reduced | -88 |
| Wellington Shields Capital Management, LLC | Reduced | -49 |
| AdvisorNet Financial, Inc | Sold out | -26 |
Biggest calls
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | Added | $0300 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
He Wei-Wu
13D · may seek influence
+5.8 pts · filed 2026-05-18
Stated purposeOn April 17, 2026, ETP Global III Fund L.P. purchased a convertible note with the principal amount of US$5 million as the fourth tranche of the Issuer's US$20 million convertible note financing pursuant to certain convertible note purchase agreement (the "Purchase Agreement") between ETP Global III Fund L.P. and the Issuer dated December 11, 2025. A convertible note with a principal amount of US$5 million has been issued to the Purchaser on the same date (the "Convertible Note"). The Purchaser has the right to convert such note into the Company's ordinary shares, par value US$0.0001 per share (the "Ordinary Shares") at any time from and including the 91st day after the issuance thereof to and including the maturity date at a conversion price of the volume weighted average closing price of … Full filing |
58.8% |
| Panacea Innovation Ltd 13D · may seek influence +2.6 pts · filed 2025-12-17 | 22.5% |
| Huang James 13G · passive investor filed 2025-07-23 | 13.8% |
| Chen Zhenfeng M 13G · passive new · filed 2025-11-26 | 11.0% |
| Venrock Healthcare Capital Partners III, L.P. 13G · passive investor filed 2026-02-17 | 9.2% |
| SPARKLE BYTE LTD 13D · may seek influence filed 2026-01-20 | 5.0% |
Fell to 5% or below in the last year: Foresite Capital Fund VI LP (0.0%, 2026-02-13), Ho Chi Sing (4.8%, 2026-01-20)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q2 2025.
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| Venrock Adviser, LLC 0.09% of their portfolio | 987.3k $1.2m | Unchanged |
| Foresite Capital Management VI LLC 0.52% of their portfolio | 787.1k $928.8k | Reduced -542.3k |
| Woodline Partners LP 0.00% of their portfolio | 165.6k $195.5k | Added +1.3k |
| Wellington Shields Capital Management, LLC 0.02% of their portfolio | 90.8k $107.2k | Reduced -49 |
| ADAR1 Capital Management, LLC 0.01% of their portfolio | 44.1k $52.1k | Reduced -3.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 39.2k $46.3k | Added +300 |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 36.2k $42.8k | New |
| Wellington Shields & Co., LLC 0.01% of their portfolio | 30.1k $35.5k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 19.9k $22.0k | Added +10.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 18.8k $22.2k | Reduced -555 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 12.1k $14.2k | Added +12.0k |
| TWO SIGMA SECURITIES, LLC 0.00% of their portfolio | 11.6k $13.7k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 10.2k $12.0k | Reduced -11.0k |
| UBS Group AG 0.00% of their portfolio | 954 $1.1k | Reduced -2.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 505 $596 | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 365 $431 | Reduced -1.1k |
| BlackRock, Inc. 0.00% of their portfolio | 296 $349 | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 134 $158 | Unchanged |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 26 $0 | Reduced -88 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 25 $30 | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 19 $22 | New |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 0.00% of their portfolio | 13 $15 | Unchanged |
| Colonial Trust Co / SC 0.00% of their portfolio | 11 $13 | Unchanged |
| MAI Capital Management 0.00% of their portfolio | 5 $6 | Unchanged |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. — of their portfolio | 0 $0 | Unchanged |