Foresite Capital Management VI LLC

WEST HOLLYWOOD, CA · CIK 2013341 · 13F filing filed 2025-08-12

No investment adviser registration (Form ADV) found for this filer. It may be a parent company whose subsidiaries are the registered advisers, a bank or insurer, or a manager based outside the US.

$177.9m reported value -2.6% vs Q1 2025

20positions

83.9%in top 10

7 new 2 added 6 reduced 1 sold out vs Q1 2025

Holdings, Q2 2025

The small lines show how much was held over the last 4 quarters (adjusted for stock splits).

#	Security	Ticker	Shares	Value	% of portfolio	Change	Shares change
1	CG ONCOLOGY INC COM CGON	CGON	2,221,474	$57.8m32.47%	32.47%	Unchanged
2	CENTESSA PHARMACEUTICALS PLC SPONSORED ADS SPONSORED ADS		1,253,379	$16.5m9.26%	9.26%	Unchanged
3	AKERO THERAPEUTICS INC COM AKRO	AKRO	244,900	$13.1m7.35%	7.35%	Reduced -120.1k	-120,100 -32.9%
4	ALUMIS INC COM ALMS	ALMS	4,247,670	$12.7m7.16%	7.16%	Added +45.0k	+45,000 1.1%
5	RAPT THERAPEUTICS INC COM NEW RAPT	RAPT	1,562,500	$12.5m7.03%	7.03%	New
6	BICARA THERAPEUTICS INC COM BCAX	BCAX	949,260	$8.8m4.96%	4.96%	Reduced -740	-740 -0.1%
7	EDGEWISE THERAPEUTICS INC COM EWTX	EWTX	585,000	$7.7m4.31%	4.31%	Unchanged
8	HINGE HEALTH INC CL A HNGE	HNGE	135,000	$7.0m3.93%	3.93%	New
9	CORVUS PHARMACEUTICALS INC COM CRVS	CRVS	1,731,233	$6.9m3.89%	3.89%	Added +150.0k	+150,000 9.5%
10	KYMERA THERAPEUTICS INC COM KYMR	KYMR	146,332	$6.4m3.59%	3.59%	Unchanged
11	VERASTEM INC COM NEW VSTM	VSTM	1,276,520	$5.3m2.98%	2.98%	New
12	XENON PHARMACEUTICALS INC COM XENE	XENE	160,000	$5.0m2.82%	2.82%	New
13	CULLINAN THERAPEUTICS INC COM CGEM	CGEM	594,025	$4.5m2.51%	2.51%	Reduced -40.5k	-40,533 -6.4%
14	STRUCTURE THERAPEUTICS INC SPONSORED ADS GPCR	GPCR	210,000	$4.4m2.45%	2.45%	Reduced -210.0k	-210,000 -50.0%
15	ALLOGENE THERAPEUTICS INC COM ALLO	ALLO	2,875,357	$3.2m1.83%	1.83%	Reduced -572.9k	-572,918 -16.6%
16	IDEAYA BIOSCIENCES INC COM IDYA	IDYA	144,468	$3.0m1.71%	1.71%	New
17	AVIDITY BIOSCIENCES INC COM RNA	RNA	40,000	$1.1m0.64%	0.64%	New
18	SPYRE THERAPEUTICS INC COM NEW SYRE	SYRE	70,000	$1.0m0.59%	0.59%	New
19	CASI PHARMACEUTICALS INC ORD SHS CASIF	CASIF	787,121	$928.8k0.52%	0.52%	Reduced -542.3k	-542,262 -40.8%
20	VIRIDIAN THERAPEUTICS INC COM VRDN	VRDN	1,974	$27.6k0.02%	0.02%	Unchanged

Sold out since Q1 2025

Security	Ticker	Shares held before	Value then
RAPT THERAPEUTICS INC		12,500,000	$15.2m12.5m shares

Trades reported as a company insider in Q2 2025

Owning 10% or more of a company, or having someone on its board, makes this manager an insider there: it reports its trades in that company's shares on Form 4 within two business days. Open-market and private purchases and sales only.

Date	Company	Ticker	Trade	Shares	Value	Their holding
2025-05-06	ALUMIS INC 10% owner · See Footnote	ALMS	Bought	20,000	$86.8k20.0k shares	+0%
2025-05-02	ALUMIS INC 10% owner · See Footnote	ALMS	Bought	25,000	$115.5k25.0k shares	+1%