AVIDITY BIOSCIENCES INC RNA

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.2m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $28.40. Options: 7 managers hold calls ($10.4m notional), 8 hold puts ($4.2m).

Trends to Q2 2025

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

Fell to 5% or below in the last year: RA CAPITAL MANAGEMENT, L.P. (0.0%, 2026-05-15), PRICE T ROWE ASSOCIATES INC /MD/ (0.1%, 2026-02-17), JANUS HENDERSON GROUP PLC (4.6%, 2026-02-17), WELLINGTON MANAGEMENT GROUP LLP (0.5%, 2026-02-10)

Insider purchases and sales in Q2 2025

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

None reported in Q2 2025.

Holders, Q2 2025