BICARA THERAPEUTICS INC BCAX
COM · Common Stock · CUSIP 055477103
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBoston, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.0m this quarter). Holder counts are more reliable. Shares outstanding: 54.6m as of 2025-08-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $9.29. Options: 2 managers hold calls ($11.0k notional), 3 hold puts ($23.6k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2024 | 70 |
| Q4 2024 | 85 |
| Q1 2025 | 94 |
| Q2 2025 | 107 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2024 | 55 | 30 |
| Q1 2025 | 52 | 36 |
| Q2 2025 | 75 | 35 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $0 | $0 | — |
| Q4 2024 | $22.0k | $0 | 0.00 |
| Q1 2025 | $1.0k | $2.0k | 2.00 |
| Q2 2025 | $11.0k | $23.6k | 2.14 |
Biggest buyers
| Vestal Point Capital, LP | Added | +2.2m |
| Siren, L.L.C. | Added | +1.9m |
| VANGUARD GROUP INC | Added | +914.1k |
| BlackRock, Inc. | Added | +769.4k |
| MILLENNIUM MANAGEMENT LLC | Added | +715.4k |
| BANK OF AMERICA CORP /DE/ | Added | +432.8k |
| Deep Track Capital, LP | Added | +426.7k |
| Artisan Partners Limited Partnership | New | +402.8k |
| Logos Global Management LP | New | +400.0k |
| SCHRODER INVESTMENT MANAGEMENT GROUP | Added | +383.7k |
Biggest sellers
| BRAIDWELL LP | Sold out | -2.2m |
| WELLINGTON MANAGEMENT GROUP LLP | Sold out | -1.4m |
| JANUS HENDERSON GROUP PLC | Sold out | -1.3m |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Sold out | -1.2m |
| FMR LLC | Reduced | -1.1m |
| MORGAN STANLEY | Reduced | -947.7k |
| BAKER BROS. ADVISORS LP | Sold out | -833.3k |
| Fairmount Funds Management LLC | Sold out | -784.2k |
| ORBIMED ADVISORS LLC | Sold out | -298.3k |
| Schonfeld Strategic Advisors LLC | Reduced | -103.2k |
Biggest calls
| SIMPLEX TRADING, LLC | Added | $11.0k1.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| GROUP ONE TRADING LLC | New | $18.6k2.0k shares |
| SIMPLEX TRADING, LLC | Added | $5.0k600 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13D · may seek influence filed 2026-03-02 | 11.5% |
| Invus Global Management, LLC 13G · passive investor filed 2025-07-31 | 9.6% |
| Vestal Point Capital, LP 13G · institution +1.8 pts · filed 2026-05-15 | 8.3% |
| Deep Track Capital, LP 13G · passive investor +1.2 pts · filed 2026-05-15 | 6.2% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-27 | 5.4% |
Fell to 5% or below in the last year: T. Rowe Price Investment Management, Inc. (4.2%, 2026-10-07), Janus Henderson Group Ltd. (4.8%, 2026-08-13), Red Tree GP, LLC (4.8%, 2026-05-08), FMR LLC (3.2%, 2026-05-06)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 1 | $33.0m | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 1 | $1.0m | $1.0m |
| Q2 2025 | 0 | — | 1 | $165.1k | $165.1k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-06-16 | Meisner Lara Chief Legal Officer | Sold plan | $165.1k15.8k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 1.09% of their portfolio | 7.0m $64.6m | Unchanged |
| Siren, L.L.C. 2.51% of their portfolio | 5.2m $48.5m | Added +1.9m |
| Vestal Point Capital, LP 2.45% of their portfolio | 5.0m $46.5m | Added +2.2m |
| RED TREE MANAGEMENT, LLC 40.18% of their portfolio | 3.2m $29.5m | Unchanged |
| TPG GP A, LLC 1.49% of their portfolio | 3.0m $28.0m | Unchanged |
| FMR LLC 0.00% of their portfolio | 2.5m $23.6m | Reduced -1.1m |
| Deep Track Capital, LP 0.72% of their portfolio | 2.4m $22.5m | Added +426.7k |
| Omega Fund Management, LLC 13.26% of their portfolio | 2.2m $20.5m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 2.2m $20.0m | Added +352.3k |
| BlackRock, Inc. 0.00% of their portfolio | 2.1m $19.6m | Added +769.4k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.0m $18.6m | Added +914.1k |
| Blackstone Inc. 0.05% of their portfolio | 1.2m $11.4m | Added +196.0k |
| FIL Ltd 0.01% of their portfolio | 1.0m $9.4m | Unchanged |
| Foresite Capital Management VI LLC 4.96% of their portfolio | 949.3k $8.8m | Reduced -740 |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 741.0k $6.9m | Added +715.4k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 672.5k $6.2m | Added +180.8k |
| ACORN CAPITAL ADVISORS, LLC 3.91% of their portfolio | 643.4k $6.0m | Unchanged |
| Aisling Capital Management LP 1.47% of their portfolio | 568.9k $5.3m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 541.1k $5.0m | Added +170.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 451.2k $4.2m | Added +432.8k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 425.3k $4.0m | Added +383.7k |
| Artisan Partners Limited Partnership 0.01% of their portfolio | 402.8k $3.7m | New |
| Logos Global Management LP 0.50% of their portfolio | 400.0k $3.7m | New |
| Woodline Partners LP 0.02% of their portfolio | 348.7k $3.2m | Unchanged |
| NAN FUNG TRINITY (HK) LTD 0.38% of their portfolio | 342.9k $3.2m | New |
| Rock Springs Capital Management LP 0.19% of their portfolio | 336.1k $3.1m | Unchanged |
| DAFNA Capital Management LLC 0.81% of their portfolio | 317.0k $2.9m | Added +105.0k |
| Napean Trading & Investment Co (Singapore) PTE Ltd 0.68% of their portfolio | 275.9k $2.6m | Unchanged |
| READYSTATE ASSET MANAGEMENT LP 0.10% of their portfolio | 270.2k $2.5m | New |
| Schonfeld Strategic Advisors LLC 0.02% of their portfolio | 262.8k $2.4m | Reduced -103.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 231.6k $2.2m | Added +77.4k |
| TD Asset Management Inc 0.00% of their portfolio | 224.5k $2.1m | Added +93.6k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 221.5k $2.1m | New |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 216.8k $2.0m | New |
| MORGAN STANLEY 0.00% of their portfolio | 204.5k $1.9m | Reduced -947.7k |
| SECTORAL ASSET MANAGEMENT INC 1.24% of their portfolio | 201.4k $1.9m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 193.1k $1.8m | Added +40.0k |
| SUPERSTRING CAPITAL MANAGEMENT LP 2.20% of their portfolio | 189.7k $1.8m | New |
| Verition Fund Management LLC 0.01% of their portfolio | 171.0k $1.6m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 151.9k $1.4m | Added +26.2k |
| Atle Fund Management AB 0.59% of their portfolio | 147.4k $1.4m | Added +27.5k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 134.5k $1.2m | Added +121.7k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 125.8k $1.2m | Added +57.2k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 124.1k $1.2m | Added +12.7k |
| Jain Global LLC 0.02% of their portfolio | 117.9k $1.1m | New |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 102.5k $952.5k | New |
| Skandinaviska Enskilda Banken AB (publ) 0.00% of their portfolio | 99.2k $921.9k | Added +61.2k |
| Catalio Capital Management, LP 0.19% of their portfolio | 97.8k $908.6k | New |
| UBS Group AG 0.00% of their portfolio | 87.6k $813.9k | Added +21.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 80.4k $747.2k | Added +38.2k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 67.7k $628.9k | New |
| SPHERA FUNDS MANAGEMENT LTD. 0.16% of their portfolio | 65.7k $610.2k | New |
| BARCLAYS PLC 0.00% of their portfolio | 57.3k $532.6k | Added +37.1k |
| Atom Investors LP 0.05% of their portfolio | 55.1k $512.3k | New |
| SCS Capital Management LLC 0.01% of their portfolio | 53.4k $496.4k | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 51.8k $481.3k | New |
| Trexquant Investment LP 0.01% of their portfolio | 50.5k $469.1k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 46.9k $435.8k | Added +23.9k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 45.6k $423.3k | New |
| Nuveen, LLC 0.00% of their portfolio | 44.4k $412.8k | Added +19.4k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 43.2k $401.8k | Added +18.3k |
| NORGES BANK 0.00% of their portfolio | 42.9k $398.4k | Unchanged |
| XTX Topco Ltd 0.01% of their portfolio | 32.4k $301.1k | Added +4.0k |
| ALPS ADVISORS INC 0.00% of their portfolio | 29.4k $273.3k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 28.6k $265.7k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 27.7k $257.1k | Added +10.9k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 27.5k $255.2k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 27.5k $255.1k | Added +5.7k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 26.1k $242.4k | Added +22.1k |
| Walleye Capital LLC 0.00% of their portfolio | 24.3k $225.8k | New |
| ADAR1 Capital Management, LLC 0.03% of their portfolio | 22.9k $212.5k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 21.7k $201.6k | Added +11.4k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 18.7k $174.0k | Added +7.4k |
| Invesco Ltd. 0.00% of their portfolio | 16.9k $156.8k | Added +2.0k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 16.1k $149.5k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 14.2k $130.0k | Added +13.3k |
| Squarepoint Ops LLC 0.00% of their portfolio | 13.4k $124.1k | New |
| Mariner, LLC 0.00% of their portfolio | 12.4k $115.5k | New |
| CITIGROUP INC 0.00% of their portfolio | 11.5k $107.0k | Reduced -5.9k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 11.1k $103.1k | New |
| CAXTON CORP 1.03% of their portfolio | 10.9k $101.6k | Unchanged |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 9.9k $92.1k | Reduced -24.5k |
| Virtus Investment Advisers, LLC 0.03% of their portfolio | 8.1k $75.5k | Reduced -970 |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 8.1k $75.3k | Added +4.4k |
| Avanza Fonder AB 0.00% of their portfolio | 6.6k $61.0k | Reduced -86 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 4.8k $44.5k | Added +3.9k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.5k $32.5k | Added +1.5k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 3.2k $29.4k | Reduced -18.3k |
| Legal & General Group Plc 0.00% of their portfolio | 3.2k $29.3k | Added +1.2k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 2.1k $19.8k | Added +709 |
| Sterling Capital Management LLC 0.00% of their portfolio | 874 $8.1k | Added +712 |
| GAMMA Investing LLC 0.00% of their portfolio | 677 $6.3k | Added +82 |
| AMALGAMATED BANK 0.00% of their portfolio | 658 $6.0k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 433 $4.0k | New |
| US BANCORP \DE\ 0.00% of their portfolio | 410 $3.8k | Reduced -157 |
| Larson Financial Group LLC 0.00% of their portfolio | 354 $3.3k | Reduced -716 |
| Allworth Financial LP 0.00% of their portfolio | 294 $2.7k | Reduced -31 |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 285 $2.6k | Reduced -11.7k |
| Kessler Investment Group, LLC 0.00% of their portfolio | 200 $1.9k | Unchanged |
| CWM, LLC 0.00% of their portfolio | 171 $2.0k | Reduced -2.0k |