Catalio Capital Management, LP

NEW YORK, NY · CIK 1958125 · 13F filing filed 2026-08-14

SEC-registered investment adviser since 2021 · limited partnership

Assets managed$2.2bn
Staff30 · 13 in investment roles
Main clients (by assets)Private funds 65%, Other advisers 11%, Mutual funds and ETFs 7%
Private funds23 (1 hedge) · $1.4bn gross assets
Form ADV · 2026-03-31SEC adviser record

Legal entityCATALIO CAPITAL MANAGEMENT, LP (US)

Kindhedge funds, private equity, venture
Others nearbyNew York, NY, Washington, DC, Manchester

As an employer

Offices in2 countries
Private fundsprivate equity 3, other private 5, venture capital 14, hedge 1

Where they work

people there (dot area)number not reportedmain officeHover or tap a dot. Australian and UK companies are placed at their business or registered address, with their staff across the whole country.

Offices

From Form ADV: the main office and the other offices where it does advisory work (at most the 25 largest), with the people doing investment work at each. “About” is worked out: the firm's investment staff less its other offices. Each city links to the other managers there.

City	Country	People
New York, NY (main office)United States	United States	about 11
Altrincham, CheshireUnited Kingdom	United Kingdom	1
Washington, DCUnited States	United States	1

US visa salary filings

Filings FY20241
Median salary offered$225,000
Middle half$225,000 – $225,000
Job titles1

Job title	Filings	Median	Range
Senior Associate, LegalNew York, NY	1	$225,000

Source: US Department of Labor, Labor Condition Application disclosure data (certified, full-time, yearly equivalent). These are the salaries the employer committed to pay the visa roles it filed for, at least the prevailing wage for the job and place; they are not the pay of all its staff. Filed by: Catalio Capital Management, LP.

Map: places from GeoNames (CC BY 4.0), outlines from Natural Earth.

$532.1m reported value +11.2% vs Q1 2026

39positions

56.7%in top 10

11 new 15 added 8 reduced 13 sold out vs Q1 2026

Holdings, Q2 2026

The small lines show how much was held over the last 4 quarters (adjusted for stock splits).

#	Security	Ticker	Shares	Value	% of portfolio	Change	Shares change
1	AVALYN PHARMACEUTICALS INC COM SHS AVLN	AVLN	1,675,830	$55.2m10.37%	10.37%	New
2	JOHNSON & JOHNSON COM JNJ	JNJ	138,946	$35.3m6.63%	6.63%	New
3	GILEAD SCIENCES INC COM GILD	GILD	269,309	$34.0m6.39%	6.39%	Added +105.4k	+105,404 64.3%
4	BRIDGEBIO PHARMA INC COM BBIO	BBIO	455,041	$33.9m6.37%	6.37%	Added +23.0k	+23,027 5.3%
5	SYNDAX PHARMACEUTICALS INC COM SNDX	SNDX	1,215,698	$26.6m4.99%	4.99%	Added +172.0k	+172,028 16.5%
6	DEFINIUM THERAPEUTICS INC COM SHS DFTX	DFTX	562,672	$26.5m4.97%	4.97%	Reduced -475.3k	-475,312 -45.8%
7	BRISTOL-MYERS SQUIBB CO COM BMY	BMY	412,961	$23.8m4.47%	4.47%	Reduced -7.8k	-7,766 -1.9%
8	PARABILIS MEDICINES INC COM PBLS	PBLS	824,043	$22.6m4.24%	4.24%	New
9	NATERA INC COM NTRA	NTRA	82,181	$22.3m4.19%	4.19%	Added +11.3k	+11,274 15.9%
10	INCYTE CORP COM INCY	INCY	191,627	$21.7m4.08%	4.08%	Added +9.5k	+9,526 5.2%
11	SEPTERNA INC COM SEPN	SEPN	536,152	$18.0m3.37%	3.37%	Added +241.8k	+241,792 82.1%
12	MINERALYS THERAPEUTICS INC COM MLYS	MLYS	648,722	$17.5m3.29%	3.29%	Added +209.7k	+209,681 47.8%
13	HEARTFLOW INC COM HTFL	HTFL	583,055	$17.1m3.21%	3.21%	Added +179.5k	+179,467 44.5%
14	CORVUS PHARMACEUTICALS INC COM CRVS	CRVS	1,080,888	$16.1m3.03%	3.03%	Added +189.0k	+188,955 21.2%
15	STRUCTURE THERAPEUTICS INC SPONSORED ADS GPCR	GPCR	276,550	$14.8m2.79%	2.79%	Added +21.2k	+21,171 8.3%
16	PROTAGONIST THERAPEUTICS INC COM PTGX	PTGX	106,799	$13.1m2.46%	2.46%	New
17	DISC MEDICINE INC COM IRON	IRON	159,384	$11.7m2.19%	2.19%	Added +36.4k	+36,406 29.6%
18	EDWARDS LIFESCIENCES CORP COM EW	EW	124,778	$11.3m2.12%	2.12%	Reduced -19.8k	-19,829 -13.7%
19	AXSOME THERAPEUTICS INC COM AXSM	AXSM	43,182	$10.6m1.99%	1.99%	New
20	ULTRAGENYX PHARMACEUTICAL IN COM RARE	RARE	316,252	$10.6m1.98%	1.98%	Reduced -534.5k	-534,545 -62.8%
21	KAILERA THERAPEUTICS INC COMMON STOCK KLRA	KLRA	468,750	$10.3m1.94%	1.94%	New
22	KARYOPHARM THERAPEUTICS INC COM NEW KPTI	KPTI	940,855	$9.2m1.73%	1.73%	Added +43.1k	+43,146 4.8%
23	ODYSSEY THERAPEUTICS INC COMMON STOCK ODTX	ODTX	457,839	$8.6m1.61%	1.61%	New
24	ASCENDIS PHARMA A/S ORD SHS ASND	ASND	31,759	$8.5m1.59%	1.59%	New
25	KARDIGAN INC COM KARD	KARD	312,500	$7.5m1.40%	1.40%	New
26	ELEDON PHARMACEUTICALS INC COM ELDN	ELDN	1,695,071	$6.7m1.26%	1.26%	Added +55.3k	+55,255 3.4%
27	4D MOLECULAR THERAPEUTICS IN COM FDMT	FDMT	471,254	$6.3m1.18%	1.18%	New
28	VERADERMICS INC COMMON STOCK MANE	MANE	45,856	$5.6m1.06%	1.06%	Reduced -127.7k	-127,726 -73.6%
29	DYNE THERAPEUTICS INC COM DYN	DYN	244,929	$5.4m1.02%	1.02%	Reduced -38.0k	-38,025 -13.4%
30	FRACTYL HEALTH INC COM COM		6,168,749	$4.9m0.92%	0.92%	Added +676.9k	+676,883 12.3%
31	IMMUNOCORE HLDGS PLC ADS IMCR	IMCR	148,045	$4.7m0.88%	0.88%	Added +63.7k	+63,693 75.5%
32	DIANTHUS THERAPEUTICS INC COM DNTH	DNTH	32,941	$3.2m0.60%	0.60%	Reduced -527.4k	-527,367 -94.1%
33	BRIDGEBIO ONCOLOGY THERAPEUT COM NEW BBOT	BBOT	318,407	$2.4m0.46%	0.46%	New
34	PROTARA THERAPEUTICS INC COM STK TARA	TARA	520,148	$2.0m0.37%	0.37%	Reduced -59.9k	-59,876 -10.3%
35	HYPERFINE INC COM CL A HYPR	HYPR	1,320,041	$1.8m0.33%	0.33%	Unchanged
36	ATAIBECKLEY INC COM SHS ATAI	ATAI	196,858	$1.0m0.19%	0.19%	Unchanged
37	METAGENOMI INC COM MGX	MGX	528,993	$629.5k0.12%	0.12%	Unchanged
38	OUTSET MED INC COM NEW OM	OM	118,279	$511.0k0.10%	0.10%	Unchanged
39	FAETH THERAPEUTICS INC COM NEW FTH	FTH	14,718	$367.9k0.07%	0.07%	Unchanged

Sold out since Q1 2026

Security	Ticker	Shares held before	Value then
ASCENDIS PHARMA A/S		129,111	$29.5m129.1k shares
TERNS PHARMACEUTICALS INC		409,031	$21.6m409.0k shares
SOLENO THERAPEUTICS INC SLNO	SLNO	577,808	$19.3m577.8k shares
BOSTON SCIENTIFIC CORP BSX	BSX	299,318	$18.8m299.3k shares
CYTOKINETICS INC CYTK	CYTK	215,501	$14.2m215.5k shares
ADAPTIVE BIOTECHNOLOGIES COR ADPT	ADPT	722,784	$10.0m722.8k shares
KALVISTA PHARMACEUTICALS INC KALV	KALV	426,551	$8.6m426.6k shares
UNIQURE NV QURE	QURE	491,116	$8.0m491.1k shares
ABIVAX SA ABVX	ABVX	47,193	$5.3m47.2k shares
SUPERNUS PHARMACEUTICALS INC SUPN	SUPN	62,019	$3.2m62.0k shares
PHATHOM PHARMACEUTICALS INC PHAT	PHAT	247,767	$2.8m247.8k shares
NEWAMSTERDAM PHARMA COMPANY NAMS	NAMS	83,554	$2.7m83.6k shares
TYRA BIOSCIENCES INC TYRA	TYRA	67,285	$2.6m67.3k shares