ADAGE CAPITAL PARTNERS GP, L.L.C.

Boston, MA · CIK 1165408 · 13F filing filed 2026-08-14

SEC-registered investment adviser since 2012 · limited partnership

Assets managed$70.4bn
Staff62 · 42 in investment roles
Main clients (by assets)Private funds 100%
Private funds1 (1 hedge) · $70.4bn gross assets
Websiteadagecapital.com
Form ADV · 2026-03-25SEC adviser record

$71.3bn reported value +10.1% vs Q1 2026

1,002positions

29.5%in top 10

178 new 289 added 391 reduced 130 sold out vs Q1 2026

This report includes the holdings of 1 other manager that shares the investment decisions:

Adage Capital Management, L.P. – reports through this filing

Shares in two reports are counted once in each security's totals.

Holdings, Q2 2026

The small lines show how much was held over the last 4 quarters (adjusted for stock splits).

#	Security	Ticker	Shares	Value	% of portfolio	Change	Shares change
1	NVIDIA CORPORATION COM NVDA	NVDA	21,940,610	$4.4bn6.16%	6.16%	Reduced -158.2k	-158,200 -0.7%
2	APPLE INC COM AAPL	AAPL	12,992,154	$3.8bn5.27%	5.27%	Reduced -54.3k	-54,300 -0.4%
3	MICROSOFT CORP COM MSFT	MSFT	6,579,943	$2.5bn3.44%	3.44%	Added +4.3k	+4,300 0.1%
4	AMAZON COM INC COM AMZN	AMZN	8,755,160	$2.1bn2.93%	2.93%	Reduced -401.1k	-401,100 -4.4%
5	ALPHABET INC CAP STK CL A GOOGL	GOOGL	5,207,900	$1.9bn2.61%	2.61%	Reduced -7.7k	-7,700 -0.1%
6	BROADCOM INC COM AVGO	AVGO	4,196,656	$1.6bn2.22%	2.22%	Added +84.6k	+84,600 2.1%
7	ALPHABET INC CAP STK CL C GOOG	GOOG	4,215,120	$1.5bn2.09%	2.09%	Added +110.6k	+110,600 2.7%
8	MICRON TECHNOLOGY INC COM MU	MU	1,034,103	$1.2bn1.67%	1.67%	Reduced -71.5k	-71,500 -6.5%
9	META PLATFORMS INC CL A META	META	2,058,535	$1.2bn1.63%	1.63%	Reduced -800	-800 -0.0%
10	TESLA INC COM TSLA	TSLA	2,477,311	$1.0bn1.46%	1.46%	Added +62.8k	+62,811 2.6%
11	ELI LILLY & CO COM LLY	LLY	726,199	$871.0m1.22%	1.22%	Reduced -230.6k	-230,618 -24.1%
12	ADVANCED MICRO DEVICES INC COM AMD	AMD	1,444,194	$838.9m1.18%	1.18%	Added +118.6k	+118,600 8.9%
13	BERKSHIRE HATHAWAY INC DEL CL B NEW BRK.B	BRK.B	1,615,069	$808.2m1.13%	1.13%	Reduced -62.7k	-62,700 -3.7%
14	JPMORGAN CHASE & CO COM JPM	JPM	2,389,766	$782.2m1.10%	1.10%	Reduced -25.5k	-25,500 -1.1%
15	CONOCOPHILLIPS COM COP	COP	6,842,477	$711.3m1.00%	1.00%	Added +823.3k	+823,300 13.7%
16	JOHNSON & JOHNSON COM JNJ	JNJ	2,566,595	$651.8m0.91%	0.91%	Added +103.6k	+103,587 4.2%
17	INTEL CORP COM INTC	INTC	4,063,385	$567.4m0.80%	0.80%	Reduced -100.0k	-99,969 -2.4%
18	LAM RESEARCH CORP COM NEW LRCX	LRCX	1,185,720	$513.8m0.72%	0.72%	Added +27.6k	+27,600 2.4%
19	VISA INC COM CL A V	V	1,466,020	$503.0m0.71%	0.71%	Reduced -23.0k	-23,020 -1.6%
20	UNITEDHEALTH GROUP INC COM UNH	UNH	1,110,167	$461.4m0.65%	0.65%	Added +153.7k	+153,661 16.1%
21	WALMART INC COM WMT	WMT	3,648,826	$413.3m0.58%	0.58%	Reduced -13.2k	-13,200 -0.4%
22	APPLIED MATLS INC COM AMAT	AMAT	567,726	$410.5m0.58%	0.58%	Reduced -98.3k	-98,300 -14.8%
23	CISCO SYS INC COM CSCO	CSCO	3,462,621	$406.7m0.57%	0.57%	Reduced -421.9k	-421,900 -10.9%
24	ABBVIE INC COM ABBV	ABBV	1,598,568	$402.3m0.56%	0.56%	Added +128.3k	+128,297 8.7%
25	EXXON MOBIL CORP COM XOM	XOM	2,876,822	$393.3m0.55%	0.55%	Added +657.9k	+657,900 29.6%
26	CATERPILLAR INC COM CAT	CAT	367,704	$391.6m0.55%	0.55%	Reduced -19.1k	-19,100 -4.9%
27	COSTCO WHSL CORP NEW COM COST	COST	395,677	$370.1m0.52%	0.52%	Reduced -2.0k	-2,000 -0.5%
28	BANK AMERICA CORP COM BAC	BAC	6,492,673	$370.0m0.52%	0.52%	Added +93.3k	+93,300 1.5%
29	ROIVANT SCIENCES LTD SHS ROIV	ROIV	10,349,328	$366.3m0.51%	0.51%	Reduced -2.4m	-2,444,769 -19.1%
30	MASTERCARD INCORPORATED CL A MA	MA	709,610	$364.5m0.51%	0.51%	Reduced -4.0k	-4,000 -0.6%
31	DEVON ENERGY CORP NEW COM DVN	DVN	8,448,385	$349.1m0.49%	0.49%	Added +7.6m	+7,607,191 904.3%
32	PRAXIS PRECISION MEDICINES I COM NEW PRAX	PRAX	1,015,480	$340.0m0.48%	0.48%	Added +199.7k	+199,741 24.5%
33	GE AEROSPACE COM NEW GE	GE	881,663	$329.5m0.46%	0.46%	Reduced -153.1k	-153,100 -14.8%
34	PROCTER AND GAMBLE CO COM PG	PG	2,120,273	$310.9m0.44%	0.44%	Reduced -696.7k	-696,700 -24.7%
35	HOME DEPOT INC COM HD	HD	837,256	$295.3m0.41%	0.41%	Reduced -116.6k	-116,600 -12.2%
36	CHEVRON CORP NEW COM CVX	CVX	1,724,613	$285.9m0.40%	0.40%	Reduced -776.2k	-776,153 -31.0%
37	COCA COLA CO COM KO	KO	3,453,382	$280.7m0.39%	0.39%	Reduced -348.8k	-348,800 -9.2%
38	KLA CORP COM NEW KLAC	KLAC	914,840	$276.0m0.39%	0.39%	Reduced -34.7k	-34,700 -3.6%
39	GE VERNOVA INC COM GEV	GEV	234,699	$275.7m0.39%	0.39%	Added +10.2k	+10,200 4.5%
40	DOVER CORP COM DOV	DOV	1,224,468	$274.6m0.39%	0.39%	Added +502.8k	+502,822 69.7%
41	RTX CORPORATION COM RTX	RTX	1,434,057	$272.1m0.38%	0.38%	Added +21.6k	+21,600 1.5%
42	ORACLE CORP COM ORCL	ORCL	1,846,649	$270.6m0.38%	0.38%	Reduced -72.5k	-72,467 -3.8%
43	PALO ALTO NETWORKS INC COM PANW	PANW	768,300	$262.0m0.37%	0.37%	Reduced -70.6k	-70,600 -8.4%
44	SANDISK CORP COM SNDK	SNDK	115,099	$261.7m0.37%	0.37%	Added +2.9k	+2,900 2.6%
45	MERCK & CO INC COM MRK	MRK	2,030,023	$260.9m0.37%	0.37%	Reduced -657.4k	-657,416 -24.5%
46	NETFLIX INC COM NFLX	NFLX	3,602,330	$257.2m0.36%	0.36%	Reduced -30.1k	-30,100 -0.8%
47	INTERNATIONAL BUSINESS MACHS COM IBM	IBM	898,190	$252.6m0.35%	0.35%	Reduced -39.2k	-39,200 -4.2%
48	PHILIP MORRIS INTL INC COM PM	PM	1,389,954	$251.5m0.35%	0.35%	Reduced -4.6k	-4,600 -0.3%
49	AMPHENOL CORP CL A APH	APH	1,423,120	$250.9m0.35%	0.35%	Reduced -361.8k	-361,768 -20.3%
50	NORFOLK SOUTHN CORP COM NSC	NSC	766,536	$241.1m0.34%	0.34%	Reduced -87.5k	-87,500 -10.2%
51	PALANTIR TECHNOLOGIES INC CL A PLTR	PLTR	2,047,700	$238.9m0.33%	0.33%	Added +1.3k	+1,300 0.1%
52	JOHNSON CTLS INTL PLC SHS JCI	JCI	1,631,713	$238.4m0.33%	0.33%	Added +116.0k	+116,037 7.7%
53	LINDE PLC SHS LIN	LIN	452,335	$234.7m0.33%	0.33%	Reduced -1.0k	-1,000 -0.2%
54	OVINTIV INC COM OVV	OVV	4,372,109	$230.2m0.32%	0.32%	Reduced -535.0k	-535,000 -10.9%
55	VIPER ENERGY INC CL A VNOM	VNOM	5,426,609	$230.1m0.32%	0.32%	Added +421.9k	+421,919 8.4%
56	WELLS FARGO CO NEW COM WFC	WFC	2,729,296	$225.5m0.32%	0.32%	Reduced -40.2k	-40,200 -1.4%
57	MARVELL TECHNOLOGY INC COM MRVL	MRVL	745,800	$222.2m0.31%	0.31%	New
58	GOLDMAN SACHS GROUP INC COM GS	GS	216,089	$218.5m0.31%	0.31%	Added +761	+761 0.3%
59	TEXAS INSTRS INC COM TXN	TXN	721,644	$215.1m0.30%	0.30%	Reduced -71.4k	-71,400 -9.0%
60	ABBOTT LABS COM ABT	ABT	2,332,115	$211.6m0.30%	0.30%	Added +624.4k	+624,351 36.6%
61	THERMO FISHER SCIENTIFIC INC COM TMO	TMO	406,154	$203.6m0.29%	0.29%	Reduced -139.7k	-139,678 -25.6%
62	WESTERN DIGITAL CORP COM WDC	WDC	307,437	$196.4m0.28%	0.28%	Added +13.7k	+13,700 4.7%
63	VERTEX PHARMACEUTICALS INC COM VRTX	VRTX	393,964	$195.7m0.27%	0.27%	Added +142.0k	+141,974 56.3%
64	MORGAN STANLEY COM NEW MS	MS	929,034	$194.2m0.27%	0.27%	Reduced -43.7k	-43,700 -4.5%
65	SEAGATE TECHNOLOGY HLDNGS PL ORD SHS STX	STX	200,000	$193.0m0.27%	0.27%	Added +14.6k	+14,600 7.9%
66	ARISTA NETWORKS INC COM SHS ANET	ANET	1,105,900	$187.9m0.26%	0.26%	Added +180.8k	+180,800 19.5%
67	GALLAGHER ARTHUR J & CO COM AJG	AJG	799,003	$183.4m0.26%	0.26%	Added +458.2k	+458,240 134.5%
68	TANGO THERAPEUTICS INC COM TNGX	TNGX	5,600,000	$175.1m0.25%	0.25%	Reduced -7.2m	-7,209,485 -56.3%
69	CROWDSTRIKE HLDGS INC CL A CRWD	CRWD	224,400	$171.2m0.24%	0.24%	Added +18.6k	+18,600 9.0%
70	AMGEN INC COM AMGN	AMGN	471,833	$170.9m0.24%	0.24%	Added +129.3k	+129,333 37.8%
71	CVS HEALTH CORP COM CVS	CVS	1,639,209	$169.6m0.24%	0.24%	Added +42.6k	+42,579 2.7%
72	QUALCOMM INC COM QCOM	QCOM	910,021	$168.2m0.24%	0.24%	Reduced -45.8k	-45,800 -4.8%
73	BRIDGEBIO PHARMA INC COM BBIO	BBIO	2,252,000	$167.7m0.24%	0.24%	Added +1.7m	+1,653,000 276.0%
74	UNITED AIRLS HLDGS INC COM UAL	UAL	1,198,242	$162.9m0.23%	0.23%	Added +983.5k	+983,533 458.1%
75	CITIGROUP INC COM NEW C	C	1,136,086	$159.0m0.22%	0.22%	Added +240.6k	+240,600 26.9%
76	ANALOG DEVICES INC COM ADI	ADI	399,037	$158.5m0.22%	0.22%	Added +71.3k	+71,300 21.8%
77	MATADOR RES CO COM MTDR	MTDR	3,181,013	$158.4m0.22%	0.22%	Added +145.0k	+145,016 4.8%
78	VERIZON COMMUNICATIONS INC COM VZ	VZ	3,723,872	$157.7m0.22%	0.22%	Reduced -203.9k	-203,900 -5.2%
79	SPYRE THERAPEUTICS INC COM NEW SYRE	SYRE	1,722,300	$152.9m0.21%	0.21%	New
80	WARNER BROS DISCOVERY INC COM SER A WBD	WBD	5,733,448	$152.9m0.21%	0.21%	Reduced -683.0k	-683,039 -10.7%
81	CHUBB LIMITED COM CB	CB	441,483	$150.4m0.21%	0.21%	Reduced -154.4k	-154,400 -25.9%
82	XCEL ENERGY INC COM XEL	XEL	1,859,342	$149.3m0.21%	0.21%	Added +285.4k	+285,400 18.1%
83	ASML HOLDING N V N Y REGISTRY SHS ASML	ASML	75,000	$149.2m0.21%	0.21%	Added +20.0k	+20,000 36.4%
84	BOEING CO COM BA	BA	683,059	$147.9m0.21%	0.21%	Reduced -116.3k	-116,332 -14.6%
85	TRAVERE THERAPEUTICS INC COM TVTX	TVTX	2,569,356	$146.0m0.20%	0.20%	Added +1.6m	+1,592,356 163.0%
86	EQUINIX INC COM EQIX	EQIX	139,968	$145.9m0.20%	0.20%	Reduced -18.1k	-18,100 -11.4%
87	DISNEY WALT CO COM DIS	DIS	1,483,725	$142.8m0.20%	0.20%	Reduced -253.3k	-253,300 -14.6%
88	ANTERO RESOURCES CORP COM AR	AR	4,063,110	$142.8m0.20%	0.20%	Added +445.0k	+445,000 12.3%
89	CORNING INC COM GLW	GLW	558,421	$142.6m0.20%	0.20%	Added +84.0k	+84,000 17.7%
90	TRAVELERS COMPANIES INC COM TRV	TRV	428,104	$141.3m0.20%	0.20%	Added +92.8k	+92,800 27.7%
91	ROYALTY PHARMA PLC SHS CLASS A RPRX	RPRX	2,500,000	$140.2m0.20%	0.20%	Reduced -5.0m	-4,980,633 -66.6%
92	3M CO COM MMM	MMM	863,485	$139.8m0.20%	0.20%	Added +583.5k	+583,516 208.4%
93	TJX COS INC NEW COM TJX	TJX	922,248	$139.7m0.20%	0.20%	Added +6.4k	+6,400 0.7%
94	STANLEY BLACK & DECKER INC COM SWK	SWK	1,467,874	$138.2m0.19%	0.19%	Reduced -832.5k	-832,547 -36.2%
95	SALESFORCE INC COM CRM	CRM	879,139	$137.7m0.19%	0.19%	Reduced -210.3k	-210,300 -19.3%
96	AMERICAN ELEC PWR CO INC COM AEP	AEP	1,002,906	$137.2m0.19%	0.19%	Added +273.4k	+273,400 37.5%
97	GILEAD SCIENCES INC COM GILD	GILD	1,071,977	$135.4m0.19%	0.19%	Added +155.5k	+155,464 17.0%
98	WELLTOWER INC COM WELL	WELL	589,606	$133.8m0.19%	0.19%	Reduced -35.5k	-35,500 -5.7%
99	MONOLITHIC PWR SYS INC COM MPWR	MPWR	96,352	$133.2m0.19%	0.19%	Added +22.7k	+22,700 30.8%
100	EATON CORP PLC SHS ETN	ETN	309,098	$131.7m0.18%	0.18%	Reduced -13.8k	-13,800 -4.3%

Sold out since Q1 2026

Security	Ticker	Shares held before	Value then
CENTESSA PHARMACEUTICALS PLC		8,925,010	$354.5m8.9m shares
COTERRA ENERGY INC CTRA	CTRA	8,219,512	$288.8m8.2m shares
SOUTHERN CO SO	SO	1,186,900	$114.6m1.2m shares
TERNS PHARMACEUTICALS INC		2,124,817	$112.0m2.1m shares
VOYA FINANCIAL INC VOYA	VOYA	1,500,000	$102.5m1.5m shares
MADRIGAL PHARMACEUTICALS INC MDGL	MDGL	185,331	$97.0m185.3k shares
HONEYWELL INTL INC		204,226	$92.3m204.2k shares
HOLOGIC INC HOLX	HOLX	858,013	$64.9m858.0k shares
CHART INDS INC GTLS	GTLS	296,469	$61.3m296.5k shares
HCA HEALTHCARE INC HCA	HCA	116,200	$55.0m116.2k shares
DELTA AIR LINES INC DEL DAL	DAL	781,911	$52.0m781.9k shares
FIRSTENERGY CORP FE	FE	886,700	$44.9m886.7k shares
SHELL PLC SHEL	SHEL	480,000	$44.6m480.0k shares
HANOVER INS GROUP INC THG	THG	215,370	$37.3m215.4k shares
SUNBELT RENTALS HOLDINGS INC SUNB	SUNB	565,000	$36.8m565.0k shares
FIFTH THIRD BANCORP FITB	FITB	776,297	$36.1m776.3k shares
ERASCA INC ERAS	ERAS	2,100,000	$34.0m2.1m shares
QORVO INC QRVO	QRVO	434,311	$33.6m434.3k shares
CONSOLIDATED EDISON INC ED	ED	278,344	$31.5m278.3k shares
DUKE ENERGY CORP NEW DUK	DUK	230,113	$30.1m230.1k shares
PROTAGONIST THERAPEUTICS INC PTGX	PTGX	282,436	$29.8m282.4k shares
SIMPSON MFG INC SSD	SSD	157,500	$27.0m157.5k shares
KEMPER CORP KMPR	KMPR	800,000	$24.4m800.0k shares
AMICUS THERAPEUTICS INC FOLD	FOLD	1,650,000	$23.9m1.6m shares
AVERIN CAP ACQUISITION CORP ACAAU	ACAAU	2,250,000	$22.5m2.2m shares

Stakes above 5%

Companies where this manager has reported owning more than 5% of a class of shares, on Schedule 13D (may seek influence) or 13G (passive): its latest filing for each, from 19 Dec 2024 on.

Company	Ticker	Stake	Schedule	Last filed
SHATTUCK LABS INC STTK · 13G · filed 2025-02-12	STTK	9.8%≈ $32.4m	13G	2025-02-12
TSCAN THERAPEUTICS INC TCRX · 13G · filed 2025-02-12	TCRX	7.1%≈ $3.4m	13G	2025-02-12
SOLENO THERAPEUTICS INC SLNO · 13G · filed 2025-02-12	SLNO	6.4%	13G	2025-02-12
MEREO BIOPHARMA GROUP PLC MREO · 13G · filed 2025-02-12	MREO	5.6%	13G	2025-02-12