Vault-13

MERUS N V MRUS

COM · Common Stock · CUSIP N5749R100

181 institutional holders +23 vs Q1 2024
67,832,69267.8m shares reported held*
$4.0bnreported value*
47 new 72 added 44 reduced 24 sold out net bought ≈ $863.2m (+14.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($127.1k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $59.17. Options: 11 managers hold calls ($41.4m notional), 8 hold puts ($15.5m).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 101Q4 22: 92Q1 23: 105Q2 23: 115Q3 23: 114Q4 23: 133Q1 24: 158Q2 24: 181181Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 2022101
Q4 202292
Q1 2023105
Q2 2023115
Q3 2023114
Q4 2023133
Q1 2024158
Q2 2024181

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 45 bought or addedQ4 22: 54 cut or sold outQ4 22Q1 23: 55 bought or addedQ1 23: 30 cut or sold outQ2 23: 59 bought or addedQ2 23: 48 cut or sold outQ2 23Q3 23: 60 bought or addedQ3 23: 45 cut or sold outQ4 23: 68 bought or addedQ4 23: 53 cut or sold outQ4 23Q1 24: 85 bought or addedQ1 24: 62 cut or sold outQ2 24: 119 bought or addedQ2 24: 68 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 20224554
Q1 20235530
Q2 20235948
Q3 20236045
Q4 20236853
Q1 20248562
Q2 202411968

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$20m$40m$60mQ3 23 calls: $1.3mQ3 23 puts: $3.0mQ3 23P/C 2.26Q4 23 calls: $962.5kQ4 23 puts: $3.4mQ4 23P/C 3.54Q1 24 calls: $4.8mQ1 24 puts: $9.9mQ1 24P/C 2.06Q2 24 calls: $41.4mQ2 24 puts: $15.5mQ2 24P/C 0.37
Numbers
QuarterCallsPutsP/C
Q3 2023$1.3m$3.0m2.26
Q4 2023$962.5k$3.4m3.54
Q1 2024$4.8m$9.9m2.06
Q2 2024$41.4m$15.5m0.37

Biggest buyers

FMR LLC Added +4,562,387+4.6m
Paradigm Biocapital Advisors LP New +2,019,814+2.0m
Logos Global Management LP New +1,700,000+1.7m
Polar Capital Holdings Plc New +1,267,052+1.3m
MARSHALL WACE, LLP Added +853,060+853.1k
LORD, ABBETT & CO. LLC New +791,344+791.3k
NOVO HOLDINGS A/S New +675,000+675.0k
Holocene Advisors, LP Added +634,290+634.3k
ALLIANCEBERNSTEIN L.P. Added +594,761+594.8k
Balyasny Asset Management L.P. New +585,024+585.0k

Biggest sellers

MORGAN STANLEY Reduced -1,431,915-1.4m
Medicxi Ventures Management (Jersey) Ltd Sold out -1,169,028-1.2m
Commodore Capital LP Reduced -1,160,000-1.2m
Fairmount Funds Management LLC Sold out -717,254-717.3k
5AM Venture Management, LLC Sold out -548,825-548.8k
Venrock Adviser, LLC Reduced -527,000-527.0k
Frazier Life Sciences Management, L.P. Reduced -373,379-373.4k
Lynx1 Capital Management LP Reduced -302,300-302.3k
Saturn V Capital Management LP Reduced -211,856-211.9k
CITADEL ADVISORS LLC Reduced -170,355-170.4k

Biggest calls

JANE STREET GROUP, LLC New $21.9m370.6k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $4.7m79.7k shares
BARCLAYS PLC New $3.3m56.3k shares
Caption Management, LLC Added $3.3m55.0k shares
ORBIMED ADVISORS LLC New $3.0m50.0k shares
GROUP ONE TRADING LLC Added $2.2m37.8k shares
CITADEL ADVISORS LLC Added $2.0m33.8k shares
SIMPLEX TRADING, LLC Added $633.0k10.7k shares
HAP Trading, LLC New $302.5k55.0k shares
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) Reduced $36.8k15.0k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $6.6m112.1k shares
GOLDMAN SACHS GROUP INC Unchanged $4.7m79.8k shares
JANE STREET GROUP, LLC Added $1.9m31.5k shares
CITADEL ADVISORS LLC Added $1.8m30.4k shares
JPMORGAN CHASE & CO New $248.5k4.2k shares
SIMPLEX TRADING, LLC Reduced $207.0k3.5k shares
GROUP ONE TRADING LLC Reduced $5.9k100 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

No one currently above 5% in the filings since 19 Dec 2024.

Fell to 5% or below in the last year: Paradigm Biocapital Advisors LP (0.0%, 2026-02-17), GENMAB A/S (0.0%, 2025-12-30), RTW INVESTMENTS, LP (2.7%, 2025-11-14), WELLINGTON MANAGEMENT GROUP LLP (0.6%, 2025-11-12)

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FMR LLC 0.02% of their portfolio BOSTON, MA 6,224,9326.2m $368.3m $368.3m 0.02% Added +4.6m +4,562,387
2 RTW INVESTMENTS, LP 3.82% of their portfolio NEW YORK, NY 4,169,3934.2m $246.7m $246.7m 3.82% Added +60.0k +60,000
3 Commodore Capital LP 12.92% of their portfolio NEW YORK, NY 3,200,0003.2m $189.3m $189.3m 12.92% Reduced -1.2m -1,160,000
4 DEERFIELD MANAGEMENT COMPANY, L.P. 2.71% of their portfolio New York, NY 2,749,4012.7m $162.7m $162.7m 2.71% Added +100.0k +100,000
5 FEDERATED HERMES, INC. 0.34% of their portfolio PITTSBURGH, PA 2,398,8002.4m $141.9m $141.9m 0.34% Added +150.0k +150,000
6 SAMLYN CAPITAL, LLC 2.36% of their portfolio New York, NY 2,324,1952.3m $137.5m $137.5m 2.36% Added +247.6k +247,605
7 FRANKLIN RESOURCES INC 0.04% of their portfolio San Mateo, CA 2,106,1632.1m $124.6m $124.6m 0.04% Added +232.9k +232,915
8 Paradigm Biocapital Advisors LP 4.57% of their portfolio NEW YORK, NY 2,019,8142.0m $119.5m $119.5m 4.57% New
9 Boxer Capital, LLC 5.92% of their portfolio San Diego, CA 1,900,0001.9m $112.4m $112.4m 5.92% Unchanged
10 Logos Global Management LP 5.83% of their portfolio San Francisco, CA 1,700,0001.7m $100.6m $100.6m 5.83% New
11 WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio Boston, MA 1,662,9411.7m $98.4m $98.4m 0.02% Added +414.3k +414,301
12 Holocene Advisors, LP 0.39% of their portfolio New York, NY 1,573,8661.6m $93.1m $93.1m 0.39% Added +634.3k +634,290
13 Driehaus Capital Management LLC 0.89% of their portfolio Chicago, IL 1,550,0091.6m $91.7m $91.7m 0.89% Added +323.5k +323,518
14 BlackRock Inc. 0.00% of their portfolio New York, NY 1,525,7491.5m $90.3m $90.3m 0.00% Added +57.8k +57,825
15 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 1,501,6501.5m $88.9m $88.9m 0.01% Reduced -1.4m -1,431,915
16 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 1,385,2161.4m $82.0m $82.0m 0.01% Added +199.9k +199,862
17 Avoro Capital Advisors LLC 1.07% of their portfolio NEW YORK, NY 1,355,0001.4m $80.2m $80.2m 1.07% Added +466.1k +466,112
18 BVF INC/IL 2.12% of their portfolio San Francisco, CA 1,279,0491.3m $75.7m $75.7m 2.12% Added +106.8k +106,800
19 Polar Capital Holdings Plc 0.44% of their portfolio London, X0 1,267,0521.3m $75.0m $75.0m 0.44% New
20 Venrock Adviser, LLC 4.76% of their portfolio NEW YORK, NY 1,263,2141.3m $74.7m $74.7m 4.76% Reduced -527.0k -527,000
21 Lynx1 Capital Management LP 25.76% of their portfolio DORADO, PR 1,206,7071.2m $71.4m $71.4m 25.76% Reduced -302.3k -302,300
22 JANUS HENDERSON GROUP PLC 0.03% of their portfolio LONDON, X0 1,017,0071.0m $60.2m $60.2m 0.03% Added +474.4k +474,427
23 Rock Springs Capital Management LP 1.79% of their portfolio Baltimore, MD 1,001,0731.0m $59.2m $59.2m 1.79% Reduced -145.5k -145,487
24 Woodline Partners LP 0.54% of their portfolio San Francisco, CA 958,769958.8k $56.7m $56.7m 0.54% Added +288.0k +287,970
25 MARSHALL WACE, LLP 0.08% of their portfolio LONDON, X0 957,952958.0k $56.7m $56.7m 0.08% Added +853.1k +853,060
26 Pictet Asset Management Holding SA 0.06% of their portfolio CAROUGE, V8 844,474844.5k $50.0m $50.0m 0.06% Added +214.8k +214,799
27 Cormorant Asset Management, LP 2.89% of their portfolio BOSTON, MA 840,000840.0k $49.7m $49.7m 2.89% Added +125.0k +125,000
28 TWO SIGMA ADVISERS, LP 0.11% of their portfolio NEW YORK, NY 817,800817.8k $48.4m $48.4m 0.11% Added +99.3k +99,300
29 LORD, ABBETT & CO. LLC 0.08% of their portfolio JERSEY CITY, NJ 791,344791.3k $46.8m $46.8m 0.08% New
30 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.08% of their portfolio Boston, MA 770,000770.0k $45.6m $45.6m 0.08% Added +445.0k +445,000
31 Artal Group S.A. 1.16% of their portfolio LUXEMBOURG, N4 760,355760.4k $45.0m $45.0m 1.16% Added +305.3k +305,274
32 T. Rowe Price Investment Management, Inc. 0.03% of their portfolio BALTIMORE, MD 720,676720.7k $42.6m $42.6m 0.03% Reduced -8.3k -8,339
33 Invesco Ltd. 0.01% of their portfolio ATLANTA, GA 706,647706.6k $41.8m $41.8m 0.01% Added +578.4k +578,398
34 ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio NASHVILLE, TN 678,021678.0k $40.1m $40.1m 0.01% Added +594.8k +594,761
35 NOVO HOLDINGS A/S 2.15% of their portfolio HELLERUP, G7 675,000675.0k $39.9m $39.9m 2.15% New
36 TWO SIGMA INVESTMENTS, LP 0.09% of their portfolio NEW YORK, NY 633,227633.2k $37.5m $37.5m 0.09% Reduced -78.9k -78,882
37 SILVERARC CAPITAL MANAGEMENT, LLC 9.11% of their portfolio BOSTON, MA 623,628623.6k $36.9m $36.9m 9.11% Added +57.3k +57,341
38 Balyasny Asset Management L.P. 0.09% of their portfolio Chicago, IL 585,024585.0k $34.6m $34.6m 0.09% New
39 GREAT POINT PARTNERS LLC 5.93% of their portfolio Greenwich, CT 523,288523.3k $31.0m $31.0m 5.93% Added +300.0k +300,000
40 D. E. Shaw & Co., Inc. 0.04% of their portfolio New York, NY 521,339521.3k $30.8m $30.8m 0.04% Added +247.8k +247,813
41 DAFNA Capital Management LLC 5.79% of their portfolio LOS ANGELES, CA 409,445409.4k $24.2m $24.2m 5.79% Added +30.4k +30,450
42 Soleus Capital Management, L.P. 1.96% of their portfolio GREENWICH, CT 376,321376.3k $22.3m $22.3m 1.96% Added +180.7k +180,744
43 Frazier Life Sciences Management, L.P. 1.03% of their portfolio PALO ALTO, CA 373,100373.1k $22.1m $22.1m 1.03% Reduced -373.4k -373,379
44 Tri Locum Partners LP 5.02% of their portfolio NEW YORK, NY 335,514335.5k $19.9m $19.9m 5.02% Added +49.2k +49,192
45 First Turn Management, LLC 3.10% of their portfolio DEL MAR, CA 321,906321.9k $19.0m $19.0m 3.10% New
46 PERCEPTIVE ADVISORS LLC 0.43% of their portfolio NEW YORK, NY 300,000300.0k $17.8m $17.8m 0.43% New
47 BAKER BROS. ADVISORS LP 0.23% of their portfolio NEW YORK, NY 300,000300.0k $17.8m $17.8m 0.23% New
48 STEMPOINT CAPITAL LP 5.02% of their portfolio NEW YORK, NY 288,668288.7k $17.1m $17.1m 5.02% Added +54.8k +54,797
49 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 264,873264.9k $15.7m $15.7m 0.00% Added +20.2k +20,197
50 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 243,257243.3k $14.4m $14.4m 0.01% Added +93.0k +92,987
51 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.05% of their portfolio JUPITER, FL 214,838214.8k $12.7m $12.7m 0.05% Added +149.1k +149,137
52 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 207,209207.2k $12.3m $12.3m 0.00% Added +102.5k +102,495
53 TimesSquare Capital Management, LLC 0.17% of their portfolio NEW YORK, NY 182,220182.2k $10.8m $10.8m 0.17% New
54 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 181,853181.9k $10.8m $10.8m 0.01% Reduced -170.4k -170,355
55 Decheng Capital LLC 3.25% of their portfolio MENLO PARK, CA 179,098179.1k $10.6m $10.6m 3.25% Added +77.3k +77,300
56 Ally Bridge Group (NY) LLC 6.16% of their portfolio NEW YORK, NY 174,844174.8k $10.3m $10.3m 6.16% Reduced -81.1k -81,084
57 BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio PARIS, I0 170,844170.8k $10.1m $10.1m 0.01% Added +68.0k +67,959
58 Saturn V Capital Management LP 3.68% of their portfolio AUSTIN, TX 164,773164.8k $9.7m $9.7m 3.68% Reduced -211.9k -211,856
59 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 164,049164.0k $9.7m $9.7m 0.00% Added +7.9k +7,900
60 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 157,030157.0k $9.3m $9.3m 0.00% Reduced -61.8k -61,830
61 ORBIMED ADVISORS LLC 0.18% of their portfolio New York, NY 156,100156.1k $9.2m $9.2m 0.18% New
62 STATE OF WISCONSIN INVESTMENT BOARD 0.02% of their portfolio MADISON, WI 153,038153.0k $9.1m $9.1m 0.02% Added +130.3k +130,307
63 Aquilo Capital Management, LLC 8.45% of their portfolio SAN FRANCISCO, CA 148,109148.1k $8.8m $8.8m 8.45% Reduced -107.0k -107,000
64 SPHERA FUNDS MANAGEMENT LTD. 1.42% of their portfolio TEL AVIV, L3 147,633147.6k $8.7m $8.7m 1.42% Reduced -1.7k -1,700
65 ALGERT GLOBAL LLC 0.26% of their portfolio SAN FRANCISCO, CA 133,323133.3k $7.9m $7.9m 0.26% Added +35.5k +35,549
66 TD Asset Management Inc 0.01% of their portfolio Toronto, A6 127,554127.6k $7.5m $7.5m 0.01% Reduced -23.6k -23,620
67 Affinity Asset Advisors, LLC 1.16% of their portfolio NEW YORK, NY 125,000125.0k $7.4m $7.4m 1.16% New
68 Nan Fung Group Holdings Ltd 7.58% of their portfolio KAI TAK, K3 120,038120.0k $7.1m $7.1m 7.58% Added +30.5k +30,522
69 HighVista Strategies LLC 2.52% of their portfolio BOSTON, MA 116,718116.7k $6.9m $6.9m 2.52% Reduced -5.0k -4,962
70 Ensign Peak Advisors, Inc 0.01% of their portfolio SALT LAKE CITY, UT 114,000114.0k $6.7m $6.7m 0.01% New
71 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 110,881110.9k $6.6m $6.6m 0.00% Reduced -1.2k -1,221
72 TANG CAPITAL MANAGEMENT LLC 0.60% of their portfolio SAN DIEGO, CA 100,000100.0k $5.9m $5.9m 0.60% New
73 Integral Health Asset Management, LLC 0.59% of their portfolio New York, NY 100,000100.0k $5.9m $5.9m 0.59% Reduced -65.0k -65,000
74 Rhenman & Partners Asset Management AB 0.51% of their portfolio Stockholm, V7 90,50090.5k $5.4m $5.4m 0.51% New
75 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 84,05584.1k $5.0m $5.0m 0.00% Added +54.2k +54,205
76 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 82,64682.6k $4.9m $4.9m 0.00% Added +27.5k +27,463
77 Nicholas Investment Partners, LP 0.49% of their portfolio RANCHO SANTA FE, CA 80,50380.5k $4.8m $4.8m 0.49% New
78 Swiss National Bank 0.00% of their portfolio ZURICH, V8 78,25478.3k $4.6m $4.6m 0.00% Added +4.2k +4,200
79 FIRST TRUST ADVISORS LP 0.00% of their portfolio Wheaton, IL 77,29677.3k $4.6m $4.6m 0.00% Added +26.2k +26,233
80 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 74,54274.5k $4.4m $4.4m 0.00% Added +61.8k +61,764
81 PLATINUM INVESTMENT MANAGEMENT LTD 0.18% of their portfolio SYDNEY AUSTRALIA 2000, C3 73,72273.7k $4.4m $4.4m 0.18% Reduced -25.8k -25,768
82 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 71,98872.0k $4.3m $4.3m 0.00% Added +36.2k +36,234
83 Eversept Partners, LP 0.30% of their portfolio NEW YORK, NY 66,47466.5k $3.9m $3.9m 0.30% Reduced -53.0k -53,008
84 FRED ALGER MANAGEMENT, LLC 0.02% of their portfolio NEW YORK, NY 62,81662.8k $3.7m $3.7m 0.02% Added +42.2k +42,219
85 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 62,75262.8k $3.7m $3.7m 0.00% Reduced -9.2k -9,195
86 ExodusPoint Capital Management, LP 0.04% of their portfolio NEW YORK, NY 61,62661.6k $3.6m $3.6m 0.04% Reduced -63.0k -63,002
87 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.08% of their portfolio BALA CYNWYD, PA 56,77856.8k $3.4m $3.4m 0.08% Added +16.9k +16,868
88 DekaBank Deutsche Girozentrale 0.01% of their portfolio FRANKFURT, 2M 56,00056.0k $3.3m $3.3m 0.01% Unchanged
89 Trek Financial, LLC 0.26% of their portfolio Scottsdale, AZ 54,95755.0k $3.3m $3.3m 0.26% New
90 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 52,18652.2k $3.1m $3.1m 0.00% Reduced -5.3k -5,272
91 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.01% of their portfolio TORONTO, A6 52,00052.0k $3.1m $3.1m 0.01% Unchanged
92 CenterBook Partners LP 0.19% of their portfolio GREENWICH, CT 51,40351.4k $3.0m $3.0m 0.19% New
93 Artia Global Partners LP 0.76% of their portfolio MIAMI, FL 50,17150.2k $3.0m $3.0m 0.76% Unchanged
94 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 48,94048.9k $2.9m $2.9m 0.00% Reduced -2.6k -2,641
95 Parkman Healthcare Partners LLC 0.36% of their portfolio STAMFORD, CT 45,15245.2k $2.7m $2.7m 0.36% Reduced -35.0k -34,971
96 Exome Asset Management LLC 2.38% of their portfolio NEW YORK, NY 45,10045.1k $2.7m $2.7m 2.38% New
97 Atom Investors LP 0.26% of their portfolio AUSTIN, TX 43,82743.8k $2.6m $2.6m 0.26% Reduced -26.7k -26,744
98 TUDOR INVESTMENT CORP ET AL 0.03% of their portfolio STAMFORD, CT 42,35942.4k $2.5m $2.5m 0.03% Added +10.3k +10,313
99 Carmignac Gestion 0.04% of their portfolio PARIS, I0 42,27842.3k $2.5m $2.5m 0.04% Added +3.1k +3,106
100 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 40,63340.6k $2.4m $2.4m 0.00% Added +9.5k +9,488