Vault-13

KALVISTA PHARMACEUTICALS INC KALV

COM · Common Stock · CUSIP 483497103

120 institutional holders -10 vs Q1 2024
48,296,04248.3m shares reported held*
$568.9mreported value*
16 new 45 added 33 reduced 28 sold out net bought ≈ $2.2m (+181.5k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($72.8k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $11.78. Options: 5 managers hold calls ($372.9k notional), 5 hold puts ($441.0k).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 94Q4 22: 91Q1 23: 90Q2 23: 96Q3 23: 102Q4 23: 94Q1 24: 130Q2 24: 120120Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 202294
Q4 202291
Q1 202390
Q2 202396
Q3 2023102
Q4 202394
Q1 2024130
Q2 2024120

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 47 bought or addedQ4 22: 53 cut or sold outQ4 22Q1 23: 40 bought or addedQ1 23: 46 cut or sold outQ2 23: 53 bought or addedQ2 23: 36 cut or sold outQ2 23Q3 23: 52 bought or addedQ3 23: 38 cut or sold outQ4 23: 54 bought or addedQ4 23: 44 cut or sold outQ4 23Q1 24: 79 bought or addedQ1 24: 45 cut or sold outQ2 24: 61 bought or addedQ2 24: 61 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 20224753
Q1 20234046
Q2 20235336
Q3 20235238
Q4 20235444
Q1 20247945
Q2 20246161

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$10m$20m$30mQ3 23 calls: $10.8mQ3 23 puts: $4.1mQ3 23P/C 0.38Q4 23 calls: $21.3mQ4 23 puts: $11.3mQ4 23P/C 0.53Q1 24 calls: $1.0mQ1 24 puts: $7.0mQ1 24P/C 6.93Q2 24 calls: $372.9kQ2 24 puts: $441.0kQ2 24P/C 1.18
Numbers
QuarterCallsPutsP/C
Q3 2023$10.8m$4.1m0.38
Q4 2023$21.3m$11.3m0.53
Q1 2024$1.0m$7.0m6.93
Q2 2024$372.9k$441.0k1.18

Biggest buyers

Capital World Investors Added +1,763,014+1.8m
Vestal Point Capital, LP Added +1,645,000+1.6m
GREAT POINT PARTNERS LLC New +1,338,568+1.3m
BlackRock Inc. Added +512,882+512.9k
VANGUARD GROUP INC Added +305,475+305.5k
SCHRODER INVESTMENT MANAGEMENT GROUP Added +213,224+213.2k
STATE STREET CORP Added +162,257+162.3k
GEODE CAPITAL MANAGEMENT, LLC Added +154,383+154.4k
GOLDMAN SACHS GROUP INC Added +153,057+153.1k
Jefferies Financial Group Inc. Added +140,000+140.0k

Biggest sellers

TCG Crossover Management, LLC Sold out -1,163,356-1.2m
MORGAN STANLEY Reduced -934,718-934.7k
MARSHALL WACE, LLP Reduced -579,976-580.0k
ADAGE CAPITAL PARTNERS GP, L.L.C. Reduced -525,000-525.0k
STEMPOINT CAPITAL LP Reduced -424,295-424.3k
Soleus Capital Management, L.P. Sold out -386,000-386.0k
Candriam S.C.A. Sold out -350,000-350.0k
Saturn V Capital Management LP Reduced -313,474-313.5k
JANE STREET GROUP, LLC Reduced -307,436-307.4k
RENAISSANCE TECHNOLOGIES LLC Sold out -243,484-243.5k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $147.2k12.5k shares
CITADEL ADVISORS LLC Reduced $109.6k9.3k shares
GROUP ONE TRADING LLC Reduced $93.1k7.9k shares
SIMPLEX TRADING, LLC Reduced $23.0k2.0k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $195.5k16.6k shares
CITADEL ADVISORS LLC Reduced $114.3k9.7k shares
GROUP ONE TRADING LLC Reduced $67.1k5.7k shares
SIMPLEX TRADING, LLC Reduced $64.0k5.5k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Capital World Investors 13G · institution filed 2025-05-13 6.4% 3.2m 2025-05-13
SILVERARC CAPITAL MANAGEMENT, LLC 13G · institution new · filed 2026-05-13 5.6% new 2.9m 2026-05-13

Fell to 5% or below in the last year: TANG CAPITAL MANAGEMENT LLC (0.0%, 2026-08-14), GLAZER CAPITAL, LLC (4.8%, 2026-06-10), Frazier Life Sciences Public Fund, L.P. (2.3%, 2026-05-21), Point72 Asset Management, L.P. (4.2%, 2026-05-15), MILLENNIUM MANAGEMENT LLC (3.7%, 2026-05-01), Vestal Point Capital, LP (1.5%, 2025-11-14)

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Venrock Adviser, LLC 4.69% of their portfolio NEW YORK, NY 6,249,7316.2m $73.6m $73.6m 4.69% Unchanged
2 TANG CAPITAL MANAGEMENT LLC 5.06% of their portfolio SAN DIEGO, CA 4,218,8294.2m $49.7m $49.7m 5.06% Added +93.5k +93,484
3 MONTANOVA CAPITAL, LLC 2.02% of their portfolio New York, NY 4,192,0054.2m $49.4m $49.4m 2.02% Unchanged
4 Frazier Life Sciences Management, L.P. 2.03% of their portfolio PALO ALTO, CA 3,687,8673.7m $43.4m $43.4m 2.03% Unchanged
5 Capital World Investors 0.01% of their portfolio LOS ANGELES, CA 3,227,6203.2m $38.0m $38.0m 0.01% Added +1.8m +1,763,014
6 BlackRock Inc. 0.00% of their portfolio New York, NY 2,945,1162.9m $34.7m $34.7m 0.00% Added +512.9k +512,882
7 Vestal Point Capital, LP 2.02% of their portfolio NEW YORK, NY 2,300,0002.3m $27.1m $27.1m 2.02% Added +1.6m +1,645,000
8 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.04% of their portfolio Boston, MA 2,050,0002.0m $24.1m $24.1m 0.04% Reduced -525.0k -525,000
9 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 1,990,5882.0m $23.4m $23.4m 0.00% Added +305.5k +305,475
10 Boxer Capital, LLC 0.99% of their portfolio San Diego, CA 1,590,0001.6m $18.7m $18.7m 0.99% Unchanged
11 GREAT POINT PARTNERS LLC 3.02% of their portfolio Greenwich, CT 1,338,5681.3m $15.8m $15.8m 3.02% New
12 Saturn V Capital Management LP 5.02% of their portfolio AUSTIN, TX 1,128,4781.1m $13.3m $13.3m 5.02% Reduced -313.5k -313,474
13 First Turn Management, LLC 2.03% of their portfolio DEL MAR, CA 1,059,5401.1m $12.5m $12.5m 2.03% Reduced -119.9k -119,880
14 MPM BIOIMPACT LLC 1.61% of their portfolio BOSTON, MA 881,937881.9k $10.4m $10.4m 1.61% Added +121.2k +121,215
15 DAFNA Capital Management LLC 2.27% of their portfolio LOS ANGELES, CA 806,973807.0k $9.5m $9.5m 2.27% Unchanged
16 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 806,271806.3k $9.5m $9.5m 0.00% Added +154.4k +154,383
17 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 756,430756.4k $8.9m $8.9m 0.00% Added +162.3k +162,257
18 STEMPOINT CAPITAL LP 2.55% of their portfolio NEW YORK, NY 736,765736.8k $8.7m $8.7m 2.55% Reduced -424.3k -424,295
19 EMERALD ADVISERS, LLC 0.32% of their portfolio LEOLA, PA 643,897643.9k $7.6m $7.6m 0.32% Reduced -27.3k -27,279
20 SILVERARC CAPITAL MANAGEMENT, LLC 1.63% of their portfolio BOSTON, MA 560,883560.9k $6.6m $6.6m 1.63% Reduced -300 -300
21 Driehaus Capital Management LLC 0.06% of their portfolio Chicago, IL 535,717535.7k $6.3m $6.3m 0.06% Reduced -5.8k -5,821
22 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 534,979535.0k $6.3m $6.3m 0.00% Reduced -44.7k -44,680
23 EMERALD MUTUAL FUND ADVISERS TRUST 0.33% of their portfolio LEOLA, PA 529,365529.4k $6.2m $6.2m 0.33% Unchanged
24 PERCEPTIVE ADVISORS LLC 0.14% of their portfolio NEW YORK, NY 500,000500.0k $5.9m $5.9m 0.14% Unchanged
25 SCHRODER INVESTMENT MANAGEMENT GROUP 0.01% of their portfolio London, X0 467,998468.0k $5.5m $5.5m 0.01% Added +213.2k +213,224
26 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 338,584338.6k $4.0m $4.0m 0.00% Reduced -934.7k -934,718
27 Rosalind Advisors, Inc. 3.15% of their portfolio TORONTO, A6 337,985338.0k $4.0m $4.0m 3.15% Added +50.0k +50,000
28 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 332,695332.7k $3.9m $3.9m 0.00% Added +14.8k +14,827
29 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 286,064286.1k $3.4m $3.4m 0.00% Added +3.2k +3,181
30 Nan Fung Group Holdings Ltd 2.76% of their portfolio KAI TAK, K3 219,277219.3k $2.6m $2.6m 2.76% Unchanged
31 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 212,888212.9k $2.5m $2.5m 0.00% Added +153.1k +153,057
32 Nicholas Investment Partners, LP 0.23% of their portfolio RANCHO SANTA FE, CA 184,358184.4k $2.2m $2.2m 0.23% Added +1.7k +1,714
33 Jefferies Financial Group Inc. 0.04% of their portfolio NEW YORK, NY 175,000175.0k $2.1m $2.1m 0.04% Added +140.0k +140,000
34 Woodline Partners LP 0.02% of their portfolio San Francisco, CA 150,462150.5k $1.8m $1.8m 0.02% Unchanged
35 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 135,600135.6k $1.6m $1.6m 0.00% Added +23.5k +23,547
36 NORGES BANK 0.00% of their portfolio OSLO, Q8 131,300131.3k $1.5m $1.5m 0.00% Not comparable
37 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.04% of their portfolio CHICAGO, IL 122,960123.0k $1.4m $1.4m 0.04% Added +41.0k +40,960
38 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 110,594110.6k $1.3m $1.3m 0.00% Added +32.5k +32,456
39 D. E. Shaw & Co., Inc. 0.00% of their portfolio New York, NY 100,061100.1k $1.2m $1.2m 0.00% Added +13.0k +12,968
40 Birchview Capital, LP 0.50% of their portfolio BURLINGTON, VT 92,00092.0k $1.1m $1.1m 0.50% Unchanged
41 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 84,02384.0k $989.8k $989.8k 0.00% Added +4.7k +4,658
42 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 80,44380.4k $947.6k $947.6k 0.00% Added +9.4k +9,376
43 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 78,68278.7k $926.9k $926.9k 0.00% New
44 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.02% of their portfolio BALA CYNWYD, PA 68,52668.5k $807.2k $807.2k 0.02% Added +52.3k +52,347
45 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 63,12263.1k $743.6k $743.6k 0.00% Reduced -83.2k -83,200
46 Zimmer Partners, LP 0.01% of their portfolio NEW YORK, NY 62,70462.7k $738.7k $738.7k 0.01% Reduced -7.3k -7,296
47 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 62,50762.5k $736.3k $736.3k 0.00% Added +38.6k +38,552
48 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 60,75560.8k $715.7k $715.7k 0.00% Added +15.8k +15,755
49 ClariVest Asset Management LLC 0.07% of their portfolio SAN DIEGO, CA 57,09657.1k $672.6k $672.6k 0.07% Added +1.5k +1,535
50 FMR LLC 0.00% of their portfolio BOSTON, MA 54,02654.0k $636.4k $636.4k 0.00% Added +3.1k +3,119
51 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 53,22853.2k $627.0k $627.0k 0.00% Added +5.9k +5,908
52 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 48,91148.9k $576.2k $576.2k 0.00% Reduced -580.0k -579,976
53 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 42,45042.5k $500.1k $500.1k 0.00% Added +12.4k +12,440
54 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 41,88041.9k $493.3k $493.3k 0.00% Reduced -139.2k -139,240
55 Skandinaviska Enskilda Banken AB (publ) 0.00% of their portfolio STOCKHOLM, V7 40,86340.9k $480.1k $480.1k 0.00% Unchanged
56 Corton Capital Inc. 0.24% of their portfolio Carrying Place, A6 39,59339.6k $466.4k $466.4k 0.24% New
57 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 38,73338.7k $456.3k $456.3k 0.00% Added +28 +28
58 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 37,01337.0k $436.0k $436.0k 0.00% Reduced -307.4k -307,436
59 HighVista Strategies LLC 0.14% of their portfolio BOSTON, MA 31,87331.9k $375.5k $375.5k 0.14% Unchanged
60 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 29,58929.6k $348.6k $348.6k 0.00% Reduced -149.1k -149,149
61 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 28,93928.9k $340.9k $340.9k 0.00% Reduced -3.8k -3,784
62 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 28,19728.2k $332.2k $332.2k 0.00% Reduced -163.5k -163,502
63 Campbell & CO Investment Adviser LLC 0.03% of their portfolio BALTIMORE, MD 25,52225.5k $300.6k $300.6k 0.03% Added +15.5k +15,518
64 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 25,35225.4k $299.0k $299.0k 0.00% Added +3.2k +3,210
65 Legato Capital Management LLC 0.04% of their portfolio San Francisco, CA 23,67423.7k $278.9k $278.9k 0.04% Unchanged
66 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 22,28922.3k $262.6k $262.6k 0.00% Added +5.5k +5,513
67 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 21,38021.4k $251.9k $251.9k 0.00% New
68 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 20,48920.5k $241.4k $241.4k 0.00% First filing
69 Atom Investors LP 0.02% of their portfolio AUSTIN, TX 19,90119.9k $234.4k $234.4k 0.02% Reduced -45.1k -45,104
70 Rathbones Group PLC 0.00% of their portfolio Liverpool, X0 19,02219.0k $224.1k $224.1k 0.00% Unchanged
71 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 18,82218.8k $221.7k $221.7k 0.00% Reduced -68.3k -68,262
72 Susquehanna Portfolio Strategies, LLC 0.01% of their portfolio Bala Cynwyd, PA 18,33818.3k $216.0k $216.0k 0.01% Unchanged
73 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 16,27016.3k $191.7k $191.7k 0.00% First filing
74 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 15,93215.9k $187.7k $187.7k 0.00% Added +1.4k +1,373
75 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 15,85815.9k $186.8k $186.8k 0.00% Added +3.7k +3,662
76 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 15,43715.4k $181.8k $181.8k 0.00% Added +3.3k +3,314
77 EVOKE WEALTH, LLC 0.27% of their portfolio Los Angeles, CA 15,37315.4k $181.1k $181.1k 0.27% New
78 Verition Fund Management LLC 0.00% of their portfolio GREENWICH, CT 15,11315.1k $178.0k $178.0k 0.00% New
79 PEAK6 Investments LLC 0.01% of their portfolio CHICAGO, IL 15,00015.0k $176.7k $176.7k 0.01% Unchanged
80 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 14,28014.3k $168.2k $168.2k 0.00% Added +308 +308
81 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 13,48613.5k $158.9k $158.9k 0.00% Reduced -6.4k -6,400
82 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 13,41513.4k $158.0k $158.0k 0.00% Added +3.1k +3,125
83 UBS Group AG 0.00% of their portfolio ZURICH, V8 13,40613.4k $157.9k $157.9k 0.00% Reduced -15.1k -15,111
84 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 12,96513.0k $152.7k $152.7k 0.00% Reduced -9.0k -8,990
85 ADAR1 Capital Management, LLC 0.03% of their portfolio AUSTIN, TX 12,02012.0k $141.6k $141.6k 0.03% Added +2.0k +2,020
86 IRONWOOD INVESTMENT MANAGEMENT LLC 0.07% of their portfolio BOSTON, MA 11,48811.5k $135.3k $135.3k 0.07% Unchanged
87 DEERFIELD MANAGEMENT COMPANY, L.P. 0.00% of their portfolio New York, NY 10,84110.8k $127.7k $127.7k 0.00% Reduced -4.5k -4,512
88 Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio VANCOUVER, A1 10,70410.7k $126.1k $126.1k 0.00% Reduced -57.5k -57,501
89 Choate Investment Advisors 0.00% of their portfolio BOSTON, MA 10,00010.0k $117.8k $117.8k 0.00% Unchanged
90 Legal & General Group Plc 0.00% of their portfolio London, X0 6,3806.4k $75.2k $75.2k 0.00% Added +3.8k +3,784
91 China Universal Asset Management Co., Ltd. 0.01% of their portfolio SHANGHAI, F4 4,9585.0k $58.4k $58.4k 0.01% Reduced -3.1k -3,066
92 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.00% of their portfolio TORONTO, A6 4,5004.5k $53.0k $53.0k 0.00% Reduced -29.0k -29,000
93 NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio ST. LOUIS, MO 4,3804.4k $51.6k $51.6k 0.00% Added +29 +29
94 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 3,7313.7k $44.0k $44.0k 0.00% Added +1.3k +1,263
95 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 3,6913.7k $43.5k $43.5k 0.00% Added +3.5k +3,525
96 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 3,5823.6k $42.0k $42.0k 0.00% Added +2.9k +2,880
97 EntryPoint Capital, LLC 0.02% of their portfolio NEW YORK, NY 3,5303.5k $41.6k $41.6k 0.02% Reduced -4.3k -4,254
98 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 3,0163.0k $35.5k $35.5k 0.00% Reduced -15.0k -14,997
99 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 2,7592.8k $32.5k $32.5k 0.00% Reduced -389 -389
100 AlphaCentric Advisors LLC 0.02% of their portfolio SAN JUAN, PR 2,5002.5k $29.4k $29.4k 0.02% Reduced -127.5k -127,500