UNIQURE NV QURE
SHS · Common Stock · CUSIP N90064101
- SectorHealth care
- IndustryPharmaceutical Preparations
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($21.0k this quarter). Holder counts are more reliable. Shares outstanding: 46.8m as of 2022-10-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $18.76. Options: 13 managers hold calls ($37.4m notional), 10 hold puts ($7.5m).
Biggest calls
| Nantahala Capital Management, LLC | — | $18.8m1.0m shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $5.0m266.7k shares |
| Caption Management, LLC | — | $3.2m170.0k shares |
| Jefferies Group LLC | — | $2.9m152.1k shares |
| CITADEL ADVISORS LLC | — | $2.8m149.7k shares |
| GROUP ONE TRADING LLC | — | $2.2m114.8k shares |
| CITIGROUP INC | — | $1.3m68.4k shares |
| JANE STREET GROUP, LLC | — | $906.0k48.3k shares |
| WOLVERINE TRADING, LLC | — | $297.0k16.6k shares |
| SIMPLEX TRADING, LLC | — | $153.0k8.2k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $2.1m110.6k shares |
| CITIGROUP INC | — | $1.3m68.4k shares |
| CITADEL ADVISORS LLC | — | $1.1m58.3k shares |
| Jefferies Group LLC | — | $855.5k45.6k shares |
| SIMPLEX TRADING, LLC | — | $804.0k42.9k shares |
| Caption Management, LLC | — | $562.0k30.0k shares |
| GROUP ONE TRADING LLC | — | $426.0k22.7k shares |
| JANE STREET GROUP, LLC | — | $330.0k17.6k shares |
| Cutler Group LLC / CA | — | $66.0k17.1k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | — | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Avoro Capital Advisors LLC 13G · institution +3.3 pts · filed 2026-02-17 | 9.9% |
| JPMORGAN CHASE & CO 13G · institution +1.5 pts · filed 2026-10-16 | 8.5% |
| RTW INVESTMENTS, LP 13G · institution +1.6 pts · filed 2026-08-14 | 5.7% |
Fell to 5% or below in the last year: SUSQUEHANNA SECURITIES, LLC (4.8%, 2026-08-14), Aberdeen Group plc (4.5%, 2026-07-20), STATE STREET CORP (3.6%, 2026-05-12), FMR LLC (2.8%, 2026-05-06), EcoR1 Capital, LLC (0.0%, 2026-02-17), Vestal Point Capital, LP (0.4%, 2025-11-14)
Insider purchases and sales in Q3 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2020 | 0 | — | 0 | — | — |
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 1 | $542.2k | — |
| Q1 2022 | 0 | — | 11 | $754.9k | — |
| Q2 2022 | 0 | — | 2 | $122.3k | — |
| Q3 2022 | 0 | — | 1 | $1.1m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-09-21 | Kuta Alexander Edward III Executive VP, Operations | Sold | $43.0k2.3k shares |
| 2022-07-28 | Kuta Alexander Edward III Executive VP, Operations | Sold | $684.0k27.4k shares |
| 2022-07-27 | Kuta Alexander Edward III Executive VP, Operations | Sold | $260.1k10.4k shares |
| 2022-07-22 | Kuta Alexander Edward III Executive VP, Operations | Sold | $141.1k5.6k shares |
| 2022-07-21 | Kuta Alexander Edward III Executive VP, Operations | Sold | $14.9k595 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2022
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.00% of their portfolio | 4.9m $91.9m | — |
| Point72 Asset Management, L.P. 0.35% of their portfolio | 4.3m $79.9m | — |
| STATE STREET CORP 0.00% of their portfolio | 3.1m $57.5m | — |
| Nantahala Capital Management, LLC 5.34% of their portfolio | 2.9m $54.4m | — |
| FMR LLC 0.01% of their portfolio | 2.7m $51.1m | — |
| PFM Health Sciences, LP 1.72% of their portfolio | 2.4m $44.9m | — |
| ORBIMED ADVISORS LLC 0.56% of their portfolio | 1.6m $30.0m | — |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.4m $26.9m | — |
| 683 Capital Management, LLC 2.08% of their portfolio | 1.4m $25.8m | — |
| Holocene Advisors, LP 0.17% of their portfolio | 1.4m $25.7m | — |
| MORGAN STANLEY 0.00% of their portfolio | 985.8k $18.5m | — |
| Aquilo Capital Management, LLC 6.64% of their portfolio | 841.5k $15.8m | — |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 733.4k $13.8m | — |
| MACQUARIE GROUP LTD 0.02% of their portfolio | 706.5k $13.3m | — |
| NORGES BANK 0.00% of their portfolio | 617.6k $11.6m | — |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC 3.27% of their portfolio | 544.5k $10.2m | — |
| Tekla Capital Management LLC 0.40% of their portfolio | 521.7k $9.8m | — |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 505.2k $9.5m | — |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 470.5k $8.8m | — |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio | 455.0k $8.5m | — |
| Integral Health Asset Management, LLC 1.65% of their portfolio | 433.0k $8.1m | — |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 396.2k $7.4m | — |
| Bank of New York Mellon Corp 0.00% of their portfolio | 333.3k $6.3m | — |
| Assenagon Asset Management S.A. 0.03% of their portfolio | 330.6k $6.2m | — |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 326.3k $6.1m | — |
| CITIGROUP INC 0.01% of their portfolio | 311.9k $5.9m | — |
| Hudson Bay Capital Management LP 0.06% of their portfolio | 295.0k $5.5m | — |
| NORDEA INVESTMENT MANAGEMENT AB 0.01% of their portfolio | 277.7k $5.2m | — |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 254.3k $4.8m | — |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.03% of their portfolio | 249.3k $4.7m | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 247.9k $4.7m | — |
| Privium Fund Management B.V. 1.62% of their portfolio | 239.0k $4.3m | — |
| Invesco Ltd. 0.00% of their portfolio | 219.8k $4.1m | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 212.3k $4.0m | — |
| PICTET ASSET MANAGEMENT SA 0.01% of their portfolio | 211.9k $4.0m | — |
| Rafferty Asset Management, LLC 0.04% of their portfolio | 210.5k $3.9m | — |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 202.9k $3.8m | — |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 201.4k $3.8m | — |
| Mirae Asset Global Investments Co., Ltd. 0.01% of their portfolio | 198.0k $3.7m | — |
| Swedbank AB 0.01% of their portfolio | 197.8k $3.7m | — |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 176.7k $3.3m | — |
| Newtyn Management, LLC 0.72% of their portfolio | 175.0k $3.3m | — |
| ExodusPoint Capital Management, LP 0.04% of their portfolio | 169.7k $3.2m | — |
| NORTHERN TRUST CORP 0.00% of their portfolio | 159.0k $3.0m | — |
| JUPITER ASSET MANAGEMENT LTD 0.04% of their portfolio | 139.7k $2.6m | — |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 121.1k $2.3m | — |
| BANQUE PICTET & CIE SA 0.02% of their portfolio | 111.5k $2.1m | — |
| Legal & General Group Plc 0.00% of their portfolio | 111.1k $2.1m | — |
| Parallax Volatility Advisers, L.P. 0.04% of their portfolio | 109.9k $2.1m | — |
| Altium Capital Management LLC 0.74% of their portfolio | 105.0k $2.0m | — |
| Allianz Asset Management GmbH 0.00% of their portfolio | 103.5k $1.9m | — |
| NOMURA HOLDINGS INC 0.02% of their portfolio | 103.1k $1.9m | — |
| Swiss National Bank 0.00% of their portfolio | 99.6k $1.9m | — |
| Vontobel Holding Ltd. 0.02% of their portfolio | 90.1k $1.7m | — |
| Henry James International Management Inc. 0.94% of their portfolio | 89.5k $1.7m | — |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 80.5k $1.5m | — |
| Caption Management, LLC 0.25% of their portfolio | 76.4k $1.4m | — |
| Public Sector Pension Investment Board 0.01% of their portfolio | 75.4k $1.4m | — |
| Vident Investment Advisory, LLC 0.05% of their portfolio | 75.2k $1.4m | — |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 73.4k $1.4m | — |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 70.4k $1.3m | — |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 70.0k $1.3m | — |
| SANDERS MORRIS HARRIS LLC 0.33% of their portfolio | 68.1k $1.3m | — |
| BLUEFIN CAPITAL MANAGEMENT, LLC 0.14% of their portfolio | 67.9k $1.3m | — |
| Carlson Capital, L.P. 0.09% of their portfolio | 60.0k $1.1m | — |
| Hennion & Walsh Asset Management, Inc. 0.07% of their portfolio | 57.6k $1.1m | — |
| Sonic Fund II, L.P. 0.64% of their portfolio | 50.0k $938.0k | — |
| UBS Group AG 0.00% of their portfolio | 48.7k $912.0k | — |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 48.6k $911.0k | — |
| Sigma Planning Corp 0.03% of their portfolio | 48.5k $911.0k | — |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 46.7k $876.0k | — |
| Granite Point Capital Management, L.P. 0.88% of their portfolio | 45.0k $844.0k | — |
| GROUP ONE TRADING LLC 0.03% of their portfolio | 42.8k $803.0k | — |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 42.6k $799.0k | — |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 42.5k $797.0k | — |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 40.7k $764.0k | — |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 39.4k $694.0k | — |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 38.6k $724.0k | — |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 0.01% of their portfolio | 37.5k $703.0k | — |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 36.1k $678.0k | — |
| VIRGINIA RETIREMENT SYSTEMS ET Al 0.01% of their portfolio | 34.8k $652.8k | — |
| YOUSIF CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 34.2k $642.0k | — |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 33.9k $635.1k | — |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 33.4k $626.0k | — |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 32.4k $607.0k | — |
| Walleye Capital LLC 0.01% of their portfolio | 32.2k $604.0k | — |
| COMERICA BANK 0.00% of their portfolio | 29.7k $549.0k | — |
| TEXAS PERMANENT SCHOOL FUND CORP 0.01% of their portfolio | 29.6k $555.0k | — |
| EXCHANGE TRADED CONCEPTS, LLC 0.02% of their portfolio | 29.5k $553.0k | — |
| SIMPLEX TRADING, LLC 0.02% of their portfolio | 29.0k $544.0k | — |
| State of Alaska, Department of Revenue 0.01% of their portfolio | 28.5k $534.0k | — |
| New York Life Investment Management LLC 0.01% of their portfolio | 28.0k $526.0k | — |
| State of Tennessee, Department of Treasury 0.00% of their portfolio | 25.9k $486.0k | — |
| ALPS ADVISORS INC 0.00% of their portfolio | 25.5k $478.0k | — |
| Cutler Group LLC / CA 0.06% of their portfolio | 24.8k $465.0k | — |
| HARBOR CAPITAL ADVISORS, INC. 0.39% of their portfolio | 22.5k $423.0k | — |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 22.3k $418.0k | — |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 21.9k $410.0k | — |
| BOENNING & SCATTERGOOD, INC. 0.08% of their portfolio | 20.0k $375.0k | — |
| Louisiana State Employees Retirement System 0.01% of their portfolio | 19.6k $368.0k | — |