ZENTALIS PHARMACEUTICALS INC ZNTL
COM · Common Stock · CUSIP 98943L107
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($8.9k this quarter). Holder counts are more reliable. Shares outstanding: 71.1m as of 2024-08-07, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $4.10. Options: 5 managers hold calls ($262.0k notional), 4 hold puts ($48.4k).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 120 |
| Q4 2022 | 105 |
| Q1 2023 | 110 |
| Q2 2023 | 134 |
| Q3 2023 | 137 |
| Q4 2023 | 120 |
| Q1 2024 | 142 |
| Q2 2024 | 145 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 51 | 51 |
| Q1 2023 | 53 | 43 |
| Q2 2023 | 92 | 38 |
| Q3 2023 | 69 | 52 |
| Q4 2023 | 61 | 68 |
| Q1 2024 | 78 | 51 |
| Q2 2024 | 79 | 64 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $4.8m | $906.4k | 0.19 |
| Q4 2023 | $17.1m | $536.3k | 0.03 |
| Q1 2024 | $1.1m | $36.2k | 0.03 |
| Q2 2024 | $262.0k | $48.4k | 0.18 |
Biggest buyers
| VANGUARD GROUP INC | Added | +1.3m |
| Decheng Capital LLC | Added | +970.9k |
| JPMORGAN CHASE & CO | Added | +874.4k |
| TWO SIGMA INVESTMENTS, LP | Added | +807.4k |
| TWO SIGMA ADVISERS, LP | Added | +695.9k |
| CITADEL ADVISORS LLC | Added | +650.5k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +399.7k |
| GOLDMAN SACHS GROUP INC | Added | +287.3k |
| GSA CAPITAL PARTNERS LLP | Added | +244.6k |
| D. E. Shaw & Co., Inc. | Added | +226.1k |
Biggest sellers
| EVENTIDE ASSET MANAGEMENT, LLC | Reduced | -3.0m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -2.6m |
| Capital International Investors | Reduced | -2.1m |
| T. Rowe Price Investment Management, Inc. | Reduced | -2.0m |
| FMR LLC | Reduced | -2.0m |
| FEDERATED HERMES, INC. | Reduced | -1.5m |
| MORGAN STANLEY | Reduced | -1.2m |
| Paradigm Biocapital Advisors LP | Sold out | -944.9k |
| STATE STREET CORP | Reduced | -733.3k |
| Verition Fund Management LLC | Reduced | -602.4k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $136.2k33.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $116.6k28.5k shares |
| SIMPLEX TRADING, LLC | Reduced | $8.0k2.1k shares |
| GROUP ONE TRADING LLC | Reduced | $1.2k300 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $27.0k6.6k shares |
| GROUP ONE TRADING LLC | New | $20.4k5.0k shares |
| SIMPLEX TRADING, LLC | New | $1.0k400 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| WALTERS GROUP 13G · passive investor -0.9 pts · filed 2026-08-19 | 18.8% |
| Walters William T 13G · passive investor +0.8 pts · filed 2025-01-31 | 9.9% |
| 5AM Opportunities II (GP), LLC 13G · passive investor new · filed 2025-12-30 | 6.4% |
| Squadron Capital Management LLC 13G · passive investor new · filed 2026-03-03 | 5.1% |
Fell to 5% or below in the last year: BlackRock, Inc. (4.1%, 2026-10-27), BARCLAYS PLC (3.2%, 2026-08-13), Matrix Capital Management Company, LP (0.0%, 2026-01-02)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 2 | $1.8m | — |
| Q4 2022 | 0 | — | 1 | $1.7m | — |
| Q1 2023 | 0 | — | 3 | $1.3m | — |
| Q2 2023 | 0 | — | 2 | $3.1m | $3.1m |
| Q3 2023 | 0 | — | 1 | $125.2k | $125.2k |
| Q4 2023 | 2 | $219.4k | 3 | $432.6k | $432.6k |
| Q1 2024 | 0 | — | 4 | $332.7k | — |
| Q2 2024 | 0 | — | 2 | $157.3k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-05-31 | Gallagher Cam President, Interim CFO, director | Sold | $115.0k9.6k shares |
| 2024-05-09 | HAUSMAN DIANA Chief Medical Officer | Sold | $42.4k3.4k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| Matrix Capital Management Company, LP 0.43% of their portfolio | 14.0m $57.1m | Unchanged |
| FMR LLC 0.00% of their portfolio | 8.7m $35.5m | Reduced -2.0m |
| EVENTIDE ASSET MANAGEMENT, LLC 0.60% of their portfolio | 8.5m $35.0m | Reduced -3.0m |
| VANGUARD GROUP INC 0.00% of their portfolio | 5.7m $23.1m | Added +1.3m |
| BlackRock Inc. 0.00% of their portfolio | 4.8m $19.7m | Added +172.8k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 4.5m $18.4m | Added +650.5k |
| Decheng Capital LLC 3.85% of their portfolio | 3.1m $12.6m | Added +970.9k |
| STATE STREET CORP 0.00% of their portfolio | 3.1m $12.5m | Reduced -733.3k |
| MORGAN STANLEY 0.00% of their portfolio | 2.0m $8.0m | Reduced -1.2m |
| Woodline Partners LP 0.06% of their portfolio | 1.5m $6.2m | Added +80.1k |
| MPM BIOIMPACT LLC 0.92% of their portfolio | 1.4m $5.9m | Reduced -66.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $5.5m | Added +32.2k |
| T. Rowe Price Investment Management, Inc. 0.00% of their portfolio | 1.3m $5.4m | Reduced -2.0m |
| PRIMECAP MANAGEMENT CO/CA/ 0.00% of their portfolio | 1.2m $5.0m | Added +67.7k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 1.1m $4.3m | Added +807.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 991.6k $4.1m | Added +874.4k |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD 0.80% of their portfolio | 961.5k $3.9m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 923.9k $3.8m | Reduced -2.6m |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 796.9k $3.3m | Added +695.9k |
| Capital International Investors 0.00% of their portfolio | 675.4k $2.8m | Reduced -2.1m |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 661.7k $2.7m | Added +399.7k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 626.7k $2.6m | Reduced -97.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 619.3k $2.5m | Added +287.3k |
| Verition Fund Management LLC 0.02% of their portfolio | 552.8k $2.3m | Reduced -602.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 508.2k $2.1m | Added +32.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 495.3k $2.0m | Reduced -28.4k |
| 5AM Venture Management, LLC 0.45% of their portfolio | 490.0k $2.0m | Unchanged |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 482.5k $2.0m | Reduced -1.5m |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 468.4k $1.9m | Added +12.5k |
| Boxer Capital, LLC 0.10% of their portfolio | 450.0k $1.8m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 392.6k $1.6m | Added +146.3k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 333.7k $1.4m | Added +43.8k |
| GSA CAPITAL PARTNERS LLP 0.07% of their portfolio | 255.2k $1.0m | Added +244.6k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 240.3k $983.0k | Added +226.1k |
| Mayo Clinic 25.27% of their portfolio | 187.1k $765.4k | Unchanged |
| XTX Topco Ltd 0.06% of their portfolio | 178.5k $729.9k | Added +167.9k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 173.0k $707.5k | Added +48.7k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 167.6k $685.3k | Reduced -130.4k |
| Squarepoint Ops LLC 0.00% of their portfolio | 148.8k $608.4k | Added +125.6k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 130.3k $533.0k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 129.1k $528.1k | Reduced -2.7k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 113.4k $463.7k | Added +45.9k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 110.7k $452.9k | Added +53.0k |
| UBS Group AG 0.00% of their portfolio | 107.1k $438.0k | Reduced -160.8k |
| Swiss National Bank 0.00% of their portfolio | 104.7k $428.2k | Added +7.3k |
| Y-Intercept (Hong Kong) Ltd 0.02% of their portfolio | 103.9k $425.0k | New |
| TD Asset Management Inc 0.00% of their portfolio | 102.9k $420.8k | Reduced -155.9k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 101.3k $414.2k | Added +81.8k |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 98.3k $1.1m | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 94.2k $385.3k | Added +11.5k |
| Virtu Financial LLC 0.03% of their portfolio | 93.2k $381.0k | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 89.0k $364.1k | Unchanged |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 83.7k $342.4k | Added +45.2k |
| Values First Advisors, Inc. 0.18% of their portfolio | 74.9k $306.4k | Added +3.9k |
| NORGES BANK 0.00% of their portfolio | 71.5k $292.5k | Reduced -71.4k |
| BARCLAYS PLC 0.00% of their portfolio | 63.6k $260.3k | Reduced -2.7k |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 60.7k $248.0k | Reduced -200 |
| ALPS ADVISORS INC 0.00% of their portfolio | 55.4k $226.6k | Added +5.4k |
| Invesco Ltd. 0.00% of their portfolio | 53.8k $220.1k | Reduced -557 |
| Legal & General Group Plc 0.00% of their portfolio | 53.3k $218.1k | Reduced -3.5k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 52.5k $214.6k | Added +2.1k |
| Prospera Financial Services Inc 0.01% of their portfolio | 48.8k $199.5k | Added +24.7k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 47.0k $192.4k | Added +3.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 44.1k $180.3k | Added +17.1k |
| CITIGROUP INC 0.00% of their portfolio | 43.9k $179.7k | Reduced -213.2k |
| SHERBROOKE PARK ADVISERS LLC 0.03% of their portfolio | 41.3k $169.1k | New |
| PDT Partners, LLC 0.02% of their portfolio | 40.3k $164.8k | Reduced -91.0k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 40.2k $164.5k | Reduced -19.1k |
| FOX RUN MANAGEMENT, L.L.C. 0.03% of their portfolio | 40.1k $163.9k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 37.5k $153.3k | Added +37.4k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 35.6k $146.3k | First filing |
| MetLife Investment Management, LLC 0.00% of their portfolio | 34.1k $139.4k | Added +3.4k |
| Pennant Investors, LP 0.04% of their portfolio | 32.4k $132.5k | Unchanged |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 32.1k $131.1k | Reduced -906 |
| Birchview Capital, LP 0.06% of their portfolio | 32.0k $130.9k | Unchanged |
| PROFUND ADVISORS LLC 0.00% of their portfolio | 30.9k $126.3k | Reduced -15.5k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 30.7k $125.7k | First filing |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 29.7k $124.7k | Added +1.8k |
| Regency Capital Management Inc.\DE 0.08% of their portfolio | 29.5k $120.7k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 28.1k $114.8k | Added +8.0k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 27.6k $112.0k | Reduced -1.2k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 24.3k $99.4k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 23.7k $97.1k | Reduced -7.1k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 23.3k $95.3k | New |
| Walleye Capital LLC 0.00% of their portfolio | 22.0k $90.1k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 21.9k $89.5k | Added +9 |
| Handelsbanken Fonder AB 0.00% of their portfolio | 21.5k $88.0k | Added +8.0k |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 21.2k $86.9k | Added +7.6k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 21.2k $86.7k | Reduced -285 |
| OCCUDO QUANTITATIVE STRATEGIES LP 0.02% of their portfolio | 21.0k $85.9k | New |
| Corton Capital Inc. 0.04% of their portfolio | 20.2k $82.6k | Added +367 |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 19.2k $78.7k | Reduced -125.4k |
| ALGERT GLOBAL LLC 0.00% of their portfolio | 19.1k $78.2k | New |
| EVERGREEN CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 16.9k $69.2k | Reduced -98 |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 16.6k $68.0k | Added +700 |
| Carson Advisory Inc. 0.05% of their portfolio | 15.8k $64.5k | Added +3.0k |
| EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio | 15.4k $63.0k | Reduced -4.8k |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 14.9k $60.9k | Added +1.3k |
| Engineers Gate Manager LP 0.00% of their portfolio | 14.6k $59.9k | Reduced -11.0k |
| OMERS ADMINISTRATION Corp 0.00% of their portfolio | 14.5k $59.3k | New |