ZENTALIS PHARMACEUTICALS INC ZNTL
COM · Common Stock · CUSIP 98943L107
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 71.0m as of 2024-05-03, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $15.76. Options: 5 managers hold calls ($1.1m notional), 2 hold puts ($36.2k).
Trends to Q1 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 120 |
| Q4 2022 | 105 |
| Q1 2023 | 110 |
| Q2 2023 | 134 |
| Q3 2023 | 137 |
| Q4 2023 | 120 |
| Q1 2024 | 142 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 51 | 51 |
| Q1 2023 | 53 | 43 |
| Q2 2023 | 92 | 38 |
| Q3 2023 | 69 | 52 |
| Q4 2023 | 61 | 68 |
| Q1 2024 | 78 | 51 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2023 | $4.4m | $1.1m | 0.24 |
| Q3 2023 | $4.8m | $906.4k | 0.19 |
| Q4 2023 | $17.1m | $536.3k | 0.03 |
| Q1 2024 | $1.1m | $36.2k | 0.03 |
Biggest buyers
| MORGAN STANLEY | Added | +1.9m |
| MPM BIOIMPACT LLC | New | +1.5m |
| T. Rowe Price Investment Management, Inc. | Added | +977.3k |
| Verition Fund Management LLC | Added | +810.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +585.6k |
| Paradigm Biocapital Advisors LP | Added | +544.9k |
| FMR LLC | Added | +307.1k |
| UBS Group AG | Added | +267.8k |
| TWO SIGMA INVESTMENTS, LP | New | +245.0k |
| MILLENNIUM MANAGEMENT LLC | Added | +215.6k |
Biggest sellers
| VANGUARD GROUP INC | Reduced | -951.8k |
| STATE STREET CORP | Reduced | -631.4k |
| Integral Health Asset Management, LLC | Sold out | -250.0k |
| BANK OF AMERICA CORP /DE/ | Reduced | -242.7k |
| Ensign Peak Advisors, Inc | Sold out | -194.9k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | Sold out | -175.5k |
| FEDERATED HERMES, INC. | Reduced | -161.9k |
| BARCLAYS PLC | Reduced | -153.2k |
| SG Americas Securities, LLC | Sold out | -152.7k |
| Caption Management, LLC | Sold out | -125.7k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $674.5k42.8k shares |
| CITADEL ADVISORS LLC | Reduced | $400.3k25.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $37.0k2.4k shares |
| GROUP ONE TRADING LLC | Reduced | $31.5k2.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $36.2k2.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| WALTERS GROUP 13G · passive investor -0.9 pts · filed 2026-08-19 | 18.8% |
| Walters William T 13G · passive investor +0.8 pts · filed 2025-01-31 | 9.9% |
| 5AM Opportunities II (GP), LLC 13G · passive investor new · filed 2025-12-30 | 6.4% |
| Squadron Capital Management LLC 13G · passive investor new · filed 2026-03-03 | 5.1% |
Fell to 5% or below in the last year: BlackRock, Inc. (4.1%, 2026-10-27), BARCLAYS PLC (3.2%, 2026-08-13), Matrix Capital Management Company, LP (0.0%, 2026-01-02)
Insider purchases and sales in Q1 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2022 | 0 | — | 4 | $2.6m | — |
| Q3 2022 | 0 | — | 2 | $1.8m | — |
| Q4 2022 | 0 | — | 1 | $1.7m | — |
| Q1 2023 | 0 | — | 3 | $1.3m | — |
| Q2 2023 | 0 | — | 2 | $3.1m | $3.1m |
| Q3 2023 | 0 | — | 1 | $125.2k | $125.2k |
| Q4 2023 | 2 | $219.4k | 3 | $432.6k | $432.6k |
| Q1 2024 | 0 | — | 4 | $332.7k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-02-12 | Epperly Melissa B, Chief Financial Officer | Sold | $29.4k2.6k shares |
| 2024-02-12 | Gallagher Cam President, director | Sold | $13.4k1.2k shares |
| 2024-02-02 | Gallagher Cam President, director | Sold | $133.3k11.6k shares |
| 2024-02-02 | Epperly Melissa B, Chief Financial Officer | Sold | $100.0k8.7k shares |
| 2024-02-02 | Paul Andrea Chief Legal Officer | Sold | $38.2k3.3k shares |
| 2024-02-02 | Lackner Mark Chief Scientific Officer | Sold | $18.3k1.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2024
| Manager | Shares | Change |
|---|---|---|
| Matrix Capital Management Company, LP 2.04% of their portfolio | 14.0m $220.0m | Unchanged |
| EVENTIDE ASSET MANAGEMENT, LLC 2.86% of their portfolio | 11.6m $182.4m | Added +14.8k |
| FMR LLC 0.01% of their portfolio | 10.6m $167.7m | Added +307.1k |
| BlackRock Inc. 0.00% of their portfolio | 4.6m $73.2m | Reduced -39.2k |
| VANGUARD GROUP INC 0.00% of their portfolio | 4.4m $69.3m | Reduced -951.8k |
| CITADEL ADVISORS LLC 0.06% of their portfolio | 3.9m $60.7m | Added +170.6k |
| STATE STREET CORP 0.00% of their portfolio | 3.8m $59.7m | Reduced -631.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 3.5m $55.0m | Added +585.6k |
| T. Rowe Price Investment Management, Inc. 0.03% of their portfolio | 3.3m $52.3m | Added +977.3k |
| MORGAN STANLEY 0.00% of their portfolio | 3.1m $49.0m | Added +1.9m |
| Capital International Investors 0.01% of their portfolio | 2.8m $44.4m | Unchanged |
| Decheng Capital LLC 4.44% of their portfolio | 2.1m $33.1m | Unchanged |
| FEDERATED HERMES, INC. 0.07% of their portfolio | 2.0m $31.5m | Reduced -161.9k |
| MPM BIOIMPACT LLC 3.87% of their portfolio | 1.5m $23.9m | New |
| Woodline Partners LP 0.21% of their portfolio | 1.4m $22.6m | Added +33.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $20.5m | Added +48.5k |
| PRIMECAP MANAGEMENT CO/CA/ 0.01% of their portfolio | 1.2m $18.4m | Added +141.3k |
| Verition Fund Management LLC 0.17% of their portfolio | 1.2m $18.2m | Added +810.6k |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD 2.59% of their portfolio | 961.5k $15.2m | Unchanged |
| Paradigm Biocapital Advisors LP 0.52% of their portfolio | 944.9k $14.9m | Added +544.9k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 723.7k $11.4m | Reduced -377 |
| NORTHERN TRUST CORP 0.00% of their portfolio | 523.7k $8.3m | Reduced -6.3k |
| 5AM Venture Management, LLC 1.73% of their portfolio | 490.0k $7.7m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 476.0k $7.5m | Reduced -242.7k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 455.9k $7.2m | Added +10.1k |
| Boxer Capital, LLC 0.35% of their portfolio | 450.0k $7.1m | Unchanged |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 332.0k $5.2m | Added +39.1k |
| Rafferty Asset Management, LLC 0.02% of their portfolio | 298.0k $4.7m | Reduced -62.1k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 289.9k $4.6m | Reduced -256 |
| UBS Group AG 0.00% of their portfolio | 267.9k $4.2m | Added +267.8k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 261.9k $4.1m | Reduced -47.3k |
| TD Asset Management Inc 0.00% of their portfolio | 258.8k $4.1m | Added +68.7k |
| CITIGROUP INC 0.00% of their portfolio | 257.1k $4.1m | Added +111.2k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 246.3k $3.9m | Added +215.6k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 245.0k $3.9m | New |
| Opaleye Management Inc. 0.69% of their portfolio | 200.0k $3.2m | New |
| Mayo Clinic 48.00% of their portfolio | 187.1k $2.9m | Unchanged |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 144.6k $2.3m | Reduced -4.2k |
| NORGES BANK 0.00% of their portfolio | 143.0k $2.3m | Reduced -21.4k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 131.8k $2.1m | Added +14.9k |
| PDT Partners, LLC 0.20% of their portfolio | 131.3k $2.1m | New |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 130.3k $2.1m | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 124.3k $2.0m | Added +78.3k |
| Jump Financial, LLC 0.05% of their portfolio | 118.6k $1.9m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 117.2k $1.8m | Reduced -69.7k |
| HRT FINANCIAL LP 0.01% of their portfolio | 113.8k $1.8m | New |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 101.0k $1.6m | New |
| Swiss National Bank 0.00% of their portfolio | 97.4k $1.5m | Unchanged |
| MARSHALL WACE, LLP 0.00% of their portfolio | 89.0k $1.4m | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 82.8k $1.3m | Added +2.0k |
| Values First Advisors, Inc. 0.66% of their portfolio | 71.1k $1.1m | Added +23.0k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 67.5k $1.1m | Added +4.3k |
| BARCLAYS PLC 0.00% of their portfolio | 66.3k $1.0m | Reduced -153.2k |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 60.9k $960.0k | Added +6.6k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 59.3k $934.0k | Added +47.9k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 57.7k $909.6k | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 56.8k $895.2k | Added +1.2k |
| Invesco Ltd. 0.00% of their portfolio | 54.4k $856.8k | Added +29.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 50.4k $794.2k | Reduced -3.2k |
| ALPS ADVISORS INC 0.01% of their portfolio | 50.1k $788.9k | Added +2.1k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 48.4k $763.4k | Reduced -479 |
| PROFUND ADVISORS LLC 0.03% of their portfolio | 46.4k $731.3k | Reduced -11.8k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 43.2k $680.4k | New |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 38.5k $606.3k | New |
| Trexquant Investment LP 0.01% of their portfolio | 37.8k $596.2k | New |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 35.3k $556.4k | New |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 33.0k $519.4k | Reduced -4.3k |
| Pennant Investors, LP 0.14% of their portfolio | 32.4k $510.6k | Unchanged |
| Birchview Capital, LP 0.21% of their portfolio | 32.0k $504.3k | Unchanged |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 31.6k $521.6k | Reduced -9.0k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 30.8k $485.8k | Reduced -12.1k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 30.7k $483.9k | Unchanged |
| Regency Capital Management Inc.\DE 0.30% of their portfolio | 29.5k $464.9k | Reduced -300 |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 28.8k $454.0k | Unchanged |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 28.7k $452.3k | Reduced -247 |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 27.9k $439.9k | Added +10.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 27.0k $425.9k | Reduced -8.6k |
| Engineers Gate Manager LP 0.01% of their portfolio | 25.6k $403.6k | New |
| New York Life Investment Management LLC 0.00% of their portfolio | 25.3k $398.8k | New |
| Prospera Financial Services Inc 0.01% of their portfolio | 24.0k $378.8k | Added +5.7k |
| Squarepoint Ops LLC 0.00% of their portfolio | 23.1k $364.2k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 21.9k $344.9k | Reduced -51 |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 21.5k $337.8k | Added +2 |
| EXCHANGE TRADED CONCEPTS, LLC 0.01% of their portfolio | 20.2k $318.4k | Added +14.2k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 20.1k $316.5k | Added +1.6k |
| Corton Capital Inc. 0.11% of their portfolio | 19.8k $312.3k | New |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 19.5k $306.9k | New |
| Entropy Technologies, LP 0.03% of their portfolio | 17.6k $276.9k | Reduced -22.9k |
| EVERGREEN CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 17.0k $268.1k | Added +98 |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 15.9k $273.8k | Reduced -700 |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 15.6k $246.1k | Added +7.8k |
| ProShare Advisors LLC 0.00% of their portfolio | 15.4k $243.3k | Added +1.3k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 15.4k $242.6k | Added +515 |
| Heritage Wealth Management, Inc. /CA/ 0.23% of their portfolio | 15.0k $236.4k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 14.3k $225.2k | New |
| E Fund Management Co., Ltd. 0.01% of their portfolio | 14.1k $221.9k | Reduced -5.3k |
| China Universal Asset Management Co., Ltd. 0.03% of their portfolio | 13.6k $214.9k | Added +5.4k |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 13.6k $214.6k | Reduced -204 |
| Brevan Howard Capital Management LP 0.02% of their portfolio | 13.6k $214.4k | New |
| Handelsbanken Fonder AB 0.00% of their portfolio | 13.5k $213.0k | Unchanged |