Vault-13

SUTRO BIOPHARMA INC

COM · CUSIP 869367102

120 institutional holders +2 vs Q1 2024
63,209,17363.2m shares reported held*
$185.2mreported value*
19 new 58 added 28 reduced 19 sold out net bought ≈ $25.2m (+8.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($48.2k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $2.93. Options: 3 managers hold calls ($586 notional), 5 hold puts ($91.4k).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 113Q4 22: 120Q1 23: 117Q2 23: 121Q3 23: 110Q4 23: 115Q1 24: 118Q2 24: 120120Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 2022113
Q4 2022120
Q1 2023117
Q2 2023121
Q3 2023110
Q4 2023115
Q1 2024118
Q2 2024120

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 73 bought or addedQ4 22: 39 cut or sold outQ4 22Q1 23: 69 bought or addedQ1 23: 51 cut or sold outQ2 23: 63 bought or addedQ2 23: 50 cut or sold outQ2 23Q3 23: 51 bought or addedQ3 23: 50 cut or sold outQ4 23: 62 bought or addedQ4 23: 44 cut or sold outQ4 23Q1 24: 69 bought or addedQ1 24: 49 cut or sold outQ2 24: 77 bought or addedQ2 24: 47 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 20227339
Q1 20236951
Q2 20236350
Q3 20235150
Q4 20236244
Q1 20246949
Q2 20247747

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$25k$50k$75k$100kQ3 23 calls: $3.5kQ3 23 puts: $3.8kQ3 23P/C 1.10Q4 23 calls: $7.3kQ4 23 puts: $4.7kQ4 23P/C 0.65Q1 24 calls: $53.9kQ1 24 puts: $13.6kQ1 24P/C 0.25Q2 24 calls: $586Q2 24 puts: $91.4kQ2 24P/C 155.95
Numbers
QuarterCallsPutsP/C
Q3 2023$3.5k$3.8k1.10
Q4 2023$7.3k$4.7k0.65
Q1 2024$53.9k$13.6k0.25
Q2 2024$586$91.4k155.95

Biggest buyers

Point72 Asset Management, L.P. Added +4,186,938+4.2m
MONTANOVA CAPITAL, LLC Added +1,930,502+1.9m
CITADEL ADVISORS LLC Added +1,279,166+1.3m
BlackRock Inc. Added +1,208,825+1.2m
Eversept Partners, LP Added +647,710+647.7k
Nuveen Asset Management, LLC Added +567,815+567.8k
VANGUARD GROUP INC Added +532,550+532.5k
SAMSARA BIOCAPITAL, LLC Added +521,235+521.2k
GEODE CAPITAL MANAGEMENT, LLC Added +438,625+438.6k
ACADIAN ASSET MANAGEMENT LLC Added +370,705+370.7k

Biggest sellers

MORGAN STANLEY Reduced -1,360,288-1.4m
MPM BIOIMPACT LLC Reduced -1,053,273-1.1m
Schonfeld Strategic Advisors LLC Reduced -488,900-488.9k
Candriam S.C.A. Sold out -440,422-440.4k
Aquilo Capital Management, LLC Reduced -402,968-403.0k
MILLENNIUM MANAGEMENT LLC Reduced -374,070-374.1k
DIMENSIONAL FUND ADVISORS LP Reduced -223,603-223.6k
Propel Bio Management, LLC Sold out -195,000-195.0k
Verition Fund Management LLC Reduced -185,733-185.7k
Cubist Systematic Strategies, LLC Reduced -177,208-177.2k

Biggest calls

CITADEL ADVISORS LLC Reduced $586200 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares
SIMPLEX TRADING, LLC Reduced $0100 shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP New $70.0k23.9k shares
CITADEL ADVISORS LLC Added $10.8k3.7k shares
SIMPLEX TRADING, LLC Added $7.0k2.7k shares
GROUP ONE TRADING LLC New $3.5k1.2k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Affinity Asset Advisors, LLC 13G · passive investor new · filed 2025-10-23 7.8% new 6.6m 2025-10-23
MILLENNIUM MANAGEMENT LLC 13G · passive investor new · filed 2025-06-30 5.6% new 4.7m 2025-06-30
Kynam Capital Management, LP 13G · institution -1.2 pts · filed 2026-05-15 5.3% -1.2 pts 0 2026-05-15

Fell to 5% or below in the last year: SUVRETTA CAPITAL MANAGEMENT, LLC (0.0%, 2026-02-13)

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 MONTANOVA CAPITAL, LLC 0.92% of their portfolio New York, NY 7,708,6907.7m $22.6m $22.6m 0.92% Added +1.9m +1,930,502
2 BlackRock Inc. 0.00% of their portfolio New York, NY 6,910,7306.9m $20.2m $20.2m 0.00% Added +1.2m +1,208,825
3 Point72 Asset Management, L.P. 0.04% of their portfolio STAMFORD, CT 4,447,6344.4m $13.0m $13.0m 0.04% Added +4.2m +4,186,938
4 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 4,361,8934.4m $12.8m $12.8m 0.01% Reduced -374.1k -374,070
5 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 3,555,3403.6m $10.4m $10.4m 0.00% Added +532.5k +532,550
6 MPM BIOIMPACT LLC 1.39% of their portfolio BOSTON, MA 3,043,3463.0m $8.9m $8.9m 1.39% Reduced -1.1m -1,053,273
7 SAMSARA BIOCAPITAL, LLC 1.35% of their portfolio PALO ALTO, CA 2,196,8142.2m $6.4m $6.4m 1.35% Added +521.2k +521,235
8 Kynam Capital Management, LP 0.62% of their portfolio PRINCETON, NJ 2,023,6832.0m $5.9m $5.9m 0.62% Added +22.0k +21,956
9 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio Boston, MA 2,000,0002.0m $5.9m $5.9m 0.01% Unchanged
10 BAILLIE GIFFORD & CO 0.00% of their portfolio EDINBURGH, X0 1,848,7511.8m $5.4m $5.4m 0.00% Added +1.8k +1,845
11 Parkman Healthcare Partners LLC 0.72% of their portfolio STAMFORD, CT 1,792,7401.8m $5.3m $5.3m 0.72% Added +2.7k +2,689
12 Eversept Partners, LP 0.39% of their portfolio NEW YORK, NY 1,739,1291.7m $5.1m $5.1m 0.39% Added +647.7k +647,710
13 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,724,9411.7m $5.1m $5.1m 0.00% Added +438.6k +438,625
14 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 1,619,9071.6m $4.7m $4.7m 0.00% Added +1.3m +1,279,166
15 ACADIAN ASSET MANAGEMENT LLC 0.01% of their portfolio Boston, MA 1,574,9581.6m $4.6m $4.6m 0.01% Added +370.7k +370,705
16 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,565,3071.6m $4.6m $4.6m 0.00% Added +368.6k +368,584
17 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 1,085,2811.1m $3.2m $3.2m 0.00% Reduced -223.6k -223,603
18 JACOBS LEVY EQUITY MANAGEMENT, INC 0.01% of their portfolio FLORHAM PARK, NJ 1,050,1891.1m $3.1m $3.1m 0.01% Reduced -19.3k -19,333
19 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 1,049,3721.0m $3.1m $3.1m 0.00% Added +246.6k +246,637
20 PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio BOSTON, MA 907,503907.5k $2.7m $2.7m 0.01% Added +122.3k +122,299
21 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 905,443905.4k $2.7m $2.7m 0.00% Added +567.8k +567,815
22 Aquilo Capital Management, LLC 2.15% of their portfolio SAN FRANCISCO, CA 762,498762.5k $2.2m $2.2m 2.15% Reduced -403.0k -402,968
23 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 719,497719.5k $2.1m $2.1m 0.00% Added +233.7k +233,700
24 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 686,500686.5k $2.0m $2.0m 0.00% Added +15.4k +15,400
25 Schonfeld Strategic Advisors LLC 0.01% of their portfolio NEW YORK, NY 634,200634.2k $1.9m $1.9m 0.01% Reduced -488.9k -488,900
26 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 503,603503.6k $1.5m $1.5m 0.00% Added +17.8k +17,839
27 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 502,648502.6k $1.5m $1.5m 0.00% Added +16.3k +16,264
28 DAFNA Capital Management LLC 0.23% of their portfolio LOS ANGELES, CA 329,579329.6k $965.7k $965.7k 0.23% Reduced -4.5k -4,500
29 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 287,810287.8k $843.3k $843.3k 0.00% Reduced -1.4m -1,360,288
30 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 283,516283.5k $830.7k $830.7k 0.00% Added +247.7k +247,694
31 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% of their portfolio CHICAGO, IL 275,057275.1k $805.9k $805.9k 0.02% Added +20.0k +20,000
32 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 272,719272.7k $799.1k $799.1k 0.00% Added +88.0k +88,034
33 Fisher Asset Management, LLC 0.00% of their portfolio PLANO, TX 271,337271.3k $795.0k $795.0k 0.00% Added +74.8k +74,820
34 GSA CAPITAL PARTNERS LLP 0.05% of their portfolio LONDON, X0 235,397235.4k $690.0k $690.0k 0.05% New
35 LPL Financial LLC 0.00% of their portfolio FORT MILL, SC 230,149230.1k $674.3k $674.3k 0.00% New
36 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.02% of their portfolio BALA CYNWYD, PA 225,367225.4k $660.3k $660.3k 0.02% Added +98.9k +98,908
37 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 216,828216.8k $635.3k $635.3k 0.00% Added +56.0k +55,952
38 Tejara Capital Ltd 0.22% of their portfolio London, X0 203,145203.1k $595.2k $595.2k 0.22% Added +8.7k +8,727
39 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio HOUSTON, TX 195,700195.7k $573.4k $573.4k 0.01% Reduced -80.0k -80,000
40 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 181,401181.4k $531.5k $531.5k 0.00% Added +32.4k +32,396
41 STRS OHIO 0.00% of their portfolio COLUMBUS, OH 165,300165.3k $484.3k $484.3k 0.00% Added +150.3k +150,300
42 FMR LLC 0.00% of their portfolio BOSTON, MA 151,340151.3k $443.4k $443.4k 0.00% Added +39.0k +39,018
43 Man Group plc 0.00% of their portfolio LONDON, X0 130,277130.3k $381.7k $381.7k 0.00% Reduced -60.4k -60,356
44 D. E. Shaw & Co., Inc. 0.00% of their portfolio New York, NY 128,665128.7k $377.0k $377.0k 0.00% Reduced -113.0k -112,978
45 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 128,231128.2k $375.7k $375.7k 0.00% Added +16.3k +16,276
46 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 116,484116.5k $341.3k $341.3k 0.00% Added +19.0k +19,000
47 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 116,099116.1k $340.2k $340.2k 0.00% Added +21.9k +21,935
48 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 105,310105.3k $308.6k $308.6k 0.00% Added +28.9k +28,890
49 Verition Fund Management LLC 0.00% of their portfolio GREENWICH, CT 97,88897.9k $286.8k $286.8k 0.00% Reduced -185.7k -185,733
50 PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio COLUMBUS, OH 96,65796.7k $283.2k $283.2k 0.00% Unchanged
51 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 96,37096.4k $282.4k $282.4k 0.00% Added +21.1k +21,070
52 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 95,48995.5k $279.8k $279.8k 0.00% Added +38.1k +38,092
53 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 95,42395.4k $279.6k $279.6k 0.00% New
54 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 82,77682.8k $242.5k $242.5k 0.00% Added +8.1k +8,137
55 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 70,61470.6k $206.9k $206.9k 0.00% New
56 Aberdeen Group plc 0.00% of their portfolio EDINBURGH, X0 69,38969.4k $203.3k $203.3k 0.00% Unchanged
57 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 66,81266.8k $195.8k $195.8k 0.00% Reduced -6.8k -6,803
58 ALPS ADVISORS INC 0.00% of their portfolio Denver, CO 63,78563.8k $186.9k $186.9k 0.00% New
59 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 62,53062.5k $183.2k $183.2k 0.00% Added +12.5k +12,486
60 HSBC HOLDINGS PLC 0.00% of their portfolio LONDON, X0 60,85860.9k $173.4k $173.4k 0.00% Added +5.4k +5,404
61 Hudson Bay Capital Management LP 0.00% of their portfolio STAMFORD, CT 60,76160.8k $178.0k $178.0k 0.00% New
62 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 56,26256.3k $164.8k $164.8k 0.00% Reduced -23.5k -23,476
63 EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio Oklahoma City, OK 54,19554.2k $158.8k $158.8k 0.00% Reduced -16.9k -16,861
64 Engineers Gate Manager LP 0.00% of their portfolio NEW YORK, NY 50,71850.7k $148.6k $148.6k 0.00% Reduced -29.9k -29,852
65 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 48,59048.6k $142.4k $142.4k 0.00% Added +18.3k +18,306
66 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 44,04044.0k $129.0k $129.0k 0.00% First filing
67 NOMURA HOLDINGS INC 0.00% of their portfolio TOKYO, M0 43,42643.4k $127.2k $127.2k 0.00% New
68 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 41,85741.9k $122.6k $122.6k 0.00% Added +14.5k +14,490
69 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 39,18639.2k $114.8k $114.8k 0.00% New
70 CORNERCAP INVESTMENT COUNSEL INC 0.02% of their portfolio Atlanta, GA 35,36035.4k $103.6k $103.6k 0.02% Reduced -330 -330
71 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 32,94332.9k $96.5k $96.5k 0.00% Added +7.1k +7,082
72 XTX Topco Ltd 0.01% of their portfolio LONDON, X0 32,35632.4k $94.8k $94.8k 0.01% Reduced -56.5k -56,540
73 UBS Group AG 0.00% of their portfolio ZURICH, V8 31,35231.4k $91.9k $91.9k 0.00% Reduced -33.3k -33,287
74 Dynamic Technology Lab Private Ltd 0.01% of their portfolio SINGAPORE, U0 31,31131.3k $92.0k $92.0k 0.01% Reduced -6.0k -5,971
75 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 30,91330.9k $90.6k $90.6k 0.00% First filing
76 PRELUDE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio NEW YORK, NY 29,98930.0k $87.9k $87.9k 0.01% Added +19.1k +19,131
77 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 28,17728.2k $82.6k $82.6k 0.00% Reduced -5.6k -5,614
78 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 27,96628.0k $81.9k $81.9k 0.00% Added +7.9k +7,911
79 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 26,26126.3k $76.9k $76.9k 0.00% Added +61 +61
80 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 26,25526.3k $77.0k $77.0k 0.00% Added +8.2k +8,228
81 Pathstone Holdings, LLC 0.00% of their portfolio ENGLEWOOD, NJ 23,45923.5k $68.7k $68.7k 0.00% Added +646 +646
82 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 19,18919.2k $56.2k $56.2k 0.00% Added +7.6k +7,606
83 SHERBROOKE PARK ADVISERS LLC 0.01% of their portfolio WHITE PLAINS, NY 19,07319.1k $55.9k $55.9k 0.01% New
84 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio TALLAHASSEE, FL 17,27317.3k $50.6k $50.6k 0.00% Added +5.0k +4,980
85 Cubist Systematic Strategies, LLC 0.00% of their portfolio STAMFORD, CT 16,46316.5k $48.2k $48.2k 0.00% Reduced -177.2k -177,208
86 ProShare Advisors LLC 0.00% of their portfolio BETHESDA, MD 16,31616.3k $47.8k $47.8k 0.00% Added +5.4k +5,373
87 Vontobel Holding Ltd. 0.00% of their portfolio ZURICH, V8 15,00015.0k $44.0k $44.0k 0.00% Unchanged
88 SG Americas Securities, LLC 0.00% of their portfolio NEW YORK, NY 14,77214.8k $43.0k $43.0k 0.00% Reduced -6.4k -6,421
89 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.00% of their portfolio BOSTON, MA 13,66113.7k $40.0k $40.0k 0.00% New
90 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 13,62513.6k $39.9k $39.9k 0.00% Added +207 +207
91 DIVERSIFIED TRUST CO 0.00% of their portfolio MEMPHIS, TN 13,03113.0k $38.2k $38.2k 0.00% Unchanged
92 Forvis Mazars Wealth Advisors, LLC 0.00% of their portfolio Springfield, MO 12,84012.8k $37.6k $37.6k 0.00% New
93 ALGERT GLOBAL LLC 0.00% of their portfolio SAN FRANCISCO, CA 12,82912.8k $37.6k $37.6k 0.00% Reduced -10.9k -10,932
94 US BANCORP \DE\ 0.00% of their portfolio MINNEAPOLIS, MN 12,00012.0k $35.2k $35.2k 0.00% Reduced -5.0k -5,000
95 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 11,88111.9k $34.8k $34.8k 0.00% Added +7.3k +7,257
96 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 11,83611.8k $34.7k $34.7k 0.00% Added +986 +986
97 State of Wyoming 0.01% of their portfolio CHEYENNE, WY 11,72511.7k $34.4k $34.4k 0.01% New
98 PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio DES MOINES, IA 10,85310.9k $31.8k $31.8k 0.00% Reduced -7.8k -7,792
99 NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio ST. LOUIS, MO 8,9068.9k $26.1k $26.1k 0.00% Added +108 +108
100 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 7,6997.7k $23.0k $23.0k 0.00% Added +6.3k +6,278