Vault-13

SOLENO THERAPEUTICS INC SLNO

COM · Common Stock · CUSIP 834203309

115 institutional holders +16 vs Q1 2024
46,407,90546.4m shares reported held*
$1.9bnreported value*
31 new 45 added 25 reduced 16 sold out net bought ≈ $455.9m (+11.2m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $40.81. Options: 5 managers hold calls ($2.1m notional), 7 hold puts ($15.7m).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 20Q4 22: 26Q1 23: 21Q2 23: 23Q3 23: 55Q4 23: 77Q1 24: 99Q2 24: 115115Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 202220
Q4 202226
Q1 202321
Q2 202323
Q3 202355
Q4 202377
Q1 202499
Q2 2024115

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 12 bought or addedQ4 22: 9 cut or sold outQ4 22Q1 23: 8 bought or addedQ1 23: 9 cut or sold outQ2 23: 6 bought or addedQ2 23: 9 cut or sold outQ2 23Q3 23: 41 bought or addedQ3 23: 12 cut or sold outQ4 23: 55 bought or addedQ4 23: 22 cut or sold outQ4 23Q1 24: 72 bought or addedQ1 24: 26 cut or sold outQ2 24: 76 bought or addedQ2 24: 41 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 2022129
Q1 202389
Q2 202369
Q3 20234112
Q4 20235522
Q1 20247226
Q2 20247641

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$5m$10m$15m$20mQ3 23 calls: $0Q3 23 puts: $0Q3 23P/C —Q4 23 calls: $2.5mQ4 23 puts: $4.0mQ4 23P/C 1.62Q1 24 calls: $17.1mQ1 24 puts: $4.1mQ1 24P/C 0.24Q2 24 calls: $2.1mQ2 24 puts: $15.7mQ2 24P/C 7.49
Numbers
QuarterCallsPutsP/C
Q3 2023$0$0—
Q4 2023$2.5m$4.0m1.62
Q1 2024$17.1m$4.1m0.24
Q2 2024$2.1m$15.7m7.49

Biggest buyers

Nantahala Capital Management, LLC Added +3,753,835+3.8m
BlackRock Inc. Added +1,537,156+1.5m
Commodore Capital LP Added +1,255,467+1.3m
ADAGE CAPITAL PARTNERS GP, L.L.C. Added +910,574+910.6k
Assenagon Asset Management S.A. New +729,841+729.8k
Holocene Advisors, LP New +536,451+536.5k
VANGUARD GROUP INC Added +533,098+533.1k
JANUS HENDERSON GROUP PLC Added +488,062+488.1k
Avoro Capital Advisors LLC Added +466,666+466.7k
Sofinnova Investments, Inc. Added +403,584+403.6k

Biggest sellers

Vivo Capital, LLC Reduced -1,101,242-1.1m
Invesco Ltd. Reduced -308,998-309.0k
MORGAN STANLEY Reduced -219,032-219.0k
MARSHALL WACE, LLP Sold out -176,237-176.2k
Ikarian Capital, LLC Reduced -119,960-120.0k
STEMPOINT CAPITAL LP Sold out -115,833-115.8k
CITIGROUP INC Reduced -86,806-86.8k
Informed Momentum Co LLC Sold out -64,411-64.4k
Rafferty Asset Management, LLC Reduced -52,207-52.2k
Ally Bridge Group (NY) LLC Reduced -50,324-50.3k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $1.0m25.5k shares
SIMPLEX TRADING, LLC Added $416.0k10.2k shares
JANE STREET GROUP, LLC New $379.4k9.3k shares
CITADEL ADVISORS LLC Reduced $257.0k6.3k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

Caption Management, LLC Added $8.8m215.2k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $4.6m112.4k shares
MILLENNIUM MANAGEMENT LLC New $816.0k20.0k shares
CITADEL ADVISORS LLC Added $754.8k18.5k shares
BOOTHBAY FUND MANAGEMENT, LLC New $648.7k15.9k shares
SIMPLEX TRADING, LLC Added $93.0k2.3k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-04-24 6.9% +1.4 pts 3.5m 2026-04-24
ADAGE CAPITAL PARTNERS GP, L.L.C. 13G · institution filed 2025-02-12 6.4% 2.8m 2025-02-12
STATE STREET CORP 13G · institution new · filed 2026-05-12 5.2% new 2.7m 2026-05-12

Fell to 5% or below in the last year: WELLINGTON MANAGEMENT GROUP LLP (0.0%, 2026-08-13), PRICE T ROWE ASSOCIATES INC /MD/ (2.0%, 2026-05-15), Avoro Capital Advisors LLC (4.5%, 2026-05-15), JANUS HENDERSON GROUP PLC (2.3%, 2026-05-07), FMR LLC (0.4%, 2026-05-07), VANGUARD GROUP INC (0.0%, 2026-03-27), Vivo Opportunity Fund Holdings, L.P. (4.2%, 2025-11-14), Adage Capital Management, L.P. (2.6%, 2025-11-13; now reported by ADAGE CAPITAL PARTNERS GP, L.L.C.)

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Vivo Capital, LLC 27.58% of their portfolio Palo Alto, CA 7,316,8517.3m $298.5m $298.5m 27.58% Reduced -1.1m -1,101,242
2 Nantahala Capital Management, LLC 12.70% of their portfolio NEW CANAAN, CT 6,164,2146.2m $251.5m $251.5m 12.70% Added +3.8m +3,753,835
3 Carlyle Group Inc. 15.80% of their portfolio WASHINGTON, DC 4,071,5624.1m $166.4m $166.4m 15.80% Unchanged
4 JANUS HENDERSON GROUP PLC 0.07% of their portfolio LONDON, X0 3,358,8733.4m $137.1m $137.1m 0.07% Added +488.1k +488,062
5 PERCEPTIVE ADVISORS LLC 3.16% of their portfolio NEW YORK, NY 3,204,9763.2m $130.8m $130.8m 3.16% Added +130.4k +130,434
6 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.22% of their portfolio Boston, MA 2,854,0942.9m $116.4m $116.4m 0.22% Added +910.6k +910,574
7 Avoro Capital Advisors LLC 1.14% of their portfolio NEW YORK, NY 2,091,6662.1m $85.3m $85.3m 1.14% Added +466.7k +466,666
8 BlackRock Inc. 0.00% of their portfolio New York, NY 1,863,4541.9m $76.0m $76.0m 0.00% Added +1.5m +1,537,156
9 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 1,502,7531.5m $61.3m $61.3m 0.00% Added +533.1k +533,098
10 Commodore Capital LP 3.97% of their portfolio NEW YORK, NY 1,425,0001.4m $58.1m $58.1m 3.97% Added +1.3m +1,255,467
11 Vestal Point Capital, LP 3.65% of their portfolio NEW YORK, NY 1,200,0001.2m $49.0m $49.0m 3.65% Reduced -50.0k -50,000
12 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,000,1361.0m $40.8m $40.8m 0.00% Added +29.6k +29,566
13 Frazier Life Sciences Management, L.P. 1.67% of their portfolio PALO ALTO, CA 875,667875.7k $35.7m $35.7m 1.67% Unchanged
14 Assenagon Asset Management S.A. 0.07% of their portfolio SENNINGERBERG, N4 729,841729.8k $29.8m $29.8m 0.07% New
15 Sofinnova Investments, Inc. 1.43% of their portfolio Menlo Park, CA 554,359554.4k $22.6m $22.6m 1.43% Added +403.6k +403,584
16 Holocene Advisors, LP 0.09% of their portfolio New York, NY 536,451536.5k $21.9m $21.9m 0.09% New
17 SAMLYN CAPITAL, LLC 0.35% of their portfolio New York, NY 501,049501.0k $20.4m $20.4m 0.35% Added +282.1k +282,122
18 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 489,107489.1k $20.0m $20.0m 0.00% Added +322.1k +322,086
19 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 477,852477.9k $19.5m $19.5m 0.00% Added +325.2k +325,232
20 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 458,520458.5k $18.7m $18.7m 0.02% Added +366.3k +366,295
21 Ikarian Capital, LLC 5.67% of their portfolio DALLAS, TX 445,451445.5k $18.2m $18.2m 5.67% Reduced -120.0k -119,960
22 Pictet Asset Management Holding SA 0.02% of their portfolio CAROUGE, V8 431,760431.8k $17.6m $17.6m 0.02% Added +97.9k +97,908
23 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 393,035393.0k $16.0m $16.0m 0.00% Added +39.6k +39,554
24 Woodline Partners LP 0.12% of their portfolio San Francisco, CA 319,205319.2k $13.0m $13.0m 0.12% Added +212.7k +212,745
25 Ghost Tree Capital, LLC 4.26% of their portfolio NEW YORK, NY 300,000300.0k $12.2m $12.2m 4.26% Added +100.0k +100,000
26 EMERALD ADVISERS, LLC 0.50% of their portfolio LEOLA, PA 293,328293.3k $12.0m $12.0m 0.50% Reduced -7.0k -7,048
27 Ally Bridge Group (NY) LLC 6.96% of their portfolio NEW YORK, NY 286,162286.2k $11.7m $11.7m 6.96% Reduced -50.3k -50,324
28 Balyasny Asset Management L.P. 0.03% of their portfolio Chicago, IL 247,214247.2k $10.1m $10.1m 0.03% Added +95.6k +95,596
29 EMERALD MUTUAL FUND ADVISERS TRUST 0.52% of their portfolio LEOLA, PA 241,099241.1k $9.8m $9.8m 0.52% Added +9.3k +9,338
30 Altium Capital Management LLC 3.59% of their portfolio NEW YORK, NY 212,909212.9k $8.7m $8.7m 3.59% Added +60.0k +60,000
31 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 201,038201.0k $8.2m $8.2m 0.00% Reduced -10.9k -10,879
32 Driehaus Capital Management LLC 0.06% of their portfolio Chicago, IL 145,110145.1k $5.9m $5.9m 0.06% New
33 Allspring Global Investments Holdings, LLC 0.01% of their portfolio CHARLOTTE, NC 133,584133.6k $5.5m $5.5m 0.01% Added +29.7k +29,745
34 SOROS FUND MANAGEMENT LLC 0.10% of their portfolio NEW YORK, NY 110,000110.0k $4.5m $4.5m 0.10% Added +10.0k +10,000
35 BOOTHBAY FUND MANAGEMENT, LLC 0.13% of their portfolio NEW YORK, NY 104,020104.0k $4.2m $4.2m 0.13% Reduced -28.0k -28,011
36 Artia Global Partners LP 0.99% of their portfolio MIAMI, FL 94,42494.4k $3.9m $3.9m 0.99% Added +53.5k +53,500
37 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 92,97793.0k $3.8m $3.8m 0.00% Reduced -219.0k -219,032
38 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 88,79988.8k $3.6m $3.6m 0.00% New
39 Caption Management, LLC 0.36% of their portfolio OKLAHOMA CITY, OK 83,72683.7k $3.4m $3.4m 0.36% Added +43.7k +43,726
40 Polar Asset Management Partners Inc. 0.08% of their portfolio TORONTO, A6 74,50074.5k $3.0m $3.0m 0.08% New
41 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 70,65570.7k $2.9m $2.9m 0.00% Reduced -2.2k -2,171
42 683 Capital Management, LLC 0.30% of their portfolio NEW YORK, NY 70,00070.0k $2.9m $2.9m 0.30% Reduced -8.0k -8,000
43 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 62,51762.5k $2.6m $2.6m 0.00% Added +55.3k +55,322
44 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 59,47859.5k $2.4m $2.4m 0.00% New
45 NORGES BANK 0.00% of their portfolio OSLO, Q8 57,77057.8k $2.4m $2.4m 0.00% Not comparable
46 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 57,53457.5k $2.3m $2.3m 0.00% Added +36.5k +36,534
47 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 56,39556.4k $2.3m $2.3m 0.00% Added +22.4k +22,427
48 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 56,31656.3k $2.3m $2.3m 0.00% Reduced -22.2k -22,184
49 Schonfeld Strategic Advisors LLC 0.02% of their portfolio NEW YORK, NY 54,01954.0k $2.2m $2.2m 0.02% Added +8.5k +8,547
50 Rafferty Asset Management, LLC 0.01% of their portfolio New York, NY 53,93753.9k $2.2m $2.2m 0.01% Reduced -52.2k -52,207
51 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 49,40849.4k $2.0m $2.0m 0.00% Added +27.0k +27,020
52 ADAR1 Capital Management, LLC 0.33% of their portfolio AUSTIN, TX 39,92939.9k $1.6m $1.6m 0.33% New
53 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 39,18439.2k $1.6m $1.6m 0.00% Added +30.2k +30,162
54 Jefferies Financial Group Inc. 0.03% of their portfolio NEW YORK, NY 35,09135.1k $1.4m $1.4m 0.03% Reduced -800 -800
55 UBS Group AG 0.00% of their portfolio ZURICH, V8 33,95034.0k $1.4m $1.4m 0.00% Reduced -19.9k -19,855
56 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 33,62433.6k $1.4m $1.4m 0.00% Added +2.5k +2,484
57 Hudson Bay Capital Management LP 0.01% of their portfolio STAMFORD, CT 30,00030.0k $1.2m $1.2m 0.01% New
58 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 29,14429.1k $1.2m $1.2m 0.00% New
59 Swiss National Bank 0.00% of their portfolio ZURICH, V8 28,80028.8k $1.2m $1.2m 0.00% Reduced -1.3k -1,300
60 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 28,40128.4k $1.2m $1.2m 0.01% Added +6.9k +6,887
61 J. Goldman & Co LP 0.04% of their portfolio NEW YORK, NY 26,93826.9k $1.1m $1.1m 0.04% New
62 MAPLELANE CAPITAL, LLC 0.08% of their portfolio New York, NY 25,00025.0k $1.0m $1.0m 0.08% Unchanged
63 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 24,61024.6k $1.0m $1.0m 0.00% New
64 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 23,53123.5k $960.1k $960.1k 0.00% Added +14.7k +14,707
65 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 21,07821.1k $860.0k $860.0k 0.00% Added +459 +459
66 Alpine Global Management, LLC 0.15% of their portfolio NEW YORK, NY 20,82420.8k $849.6k $849.6k 0.15% New
67 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 20,49820.5k $836.3k $836.3k 0.00% Added +18.6k +18,602
68 Checkpoint Capital L.P. 0.48% of their portfolio SAN FRANCISCO, CA 19,69519.7k $803.6k $803.6k 0.48% New
69 TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio STAMFORD, CT 17,70217.7k $722.2k $722.2k 0.01% Added +1.5k +1,508
70 Legal & General Group Plc 0.00% of their portfolio London, X0 16,01916.0k $653.6k $653.6k 0.00% Added +3.7k +3,736
71 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% of their portfolio CHICAGO, IL 15,00015.0k $612.0k $612.0k 0.02% Not comparable
72 SILVERARC CAPITAL MANAGEMENT, LLC 0.15% of their portfolio BOSTON, MA 15,00015.0k $612.0k $612.0k 0.15% New
73 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 14,82714.8k $604.9k $604.9k 0.00% Added +1.0k +1,047
74 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 14,07014.1k $574.1k $574.1k 0.00% Reduced -768 -768
75 SG Americas Securities, LLC 0.00% of their portfolio NEW YORK, NY 13,94113.9k $569.0k $569.0k 0.00% New
76 Cinctive Capital Management LP 0.03% of their portfolio New York, NY 13,19013.2k $538.2k $538.2k 0.03% New
77 NEOS Investment Management LLC 0.02% of their portfolio Westport, CT 12,95012.9k $528.4k $528.4k 0.02% New
78 ASPIRIANT, LLC 0.02% of their portfolio San Francisco, CA 12,12812.1k $494.8k $494.8k 0.02% Unchanged
79 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 11,83211.8k $482.9k $482.9k 0.00% First filing
80 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 11,03211.0k $450.1k $450.1k 0.00% Reduced -309.0k -308,998
81 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 10,94810.9k $446.7k $446.7k 0.00% Reduced -86.8k -86,806
82 VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio San Antonio, TX 10,72710.7k $437.7k $437.7k 0.00% Added +2.2k +2,236
83 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 10,60710.6k $432.8k $432.8k 0.00% Reduced -519 -519
84 PROFUND ADVISORS LLC 0.02% of their portfolio BETHESDA, MD 10,01510.0k $408.6k $408.6k 0.02% Reduced -6.1k -6,059
85 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 9,4699.5k $386.3k $386.3k 0.00% New
86 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 9,1179.1k $372.0k $372.0k 0.00% Added +9.0k +8,980
87 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 8,1278.1k $331.6k $331.6k 0.00% New
88 Tower Research Capital LLC (TRC) 0.01% of their portfolio NEW YORK, NY 8,0538.1k $328.6k $328.6k 0.01% Added +5.0k +4,981
89 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 7,6467.6k $312.0k $312.0k 0.00% Added +7.1k +7,082
90 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 7,3647.4k $300.5k $300.5k 0.00% New
91 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio TALLAHASSEE, FL 6,6306.6k $270.5k $270.5k 0.00% New
92 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 6,5606.6k $267.6k $267.6k 0.00% Reduced -6.0k -6,017
93 OMERS ADMINISTRATION Corp 0.00% of their portfolio TORONTO, A6 6,2006.2k $253.0k $253.0k 0.00% New
94 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 5,5765.6k $227.5k $227.5k 0.00% New
95 Ensign Peak Advisors, Inc 0.00% of their portfolio SALT LAKE CITY, UT 4,7014.7k $191.8k $191.8k 0.00% Unchanged
96 Bollard Group LLC 0.00% of their portfolio BOSTON, MA 2,2882.3k $93.0k $93.0k 0.00% Unchanged
97 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 2,1552.2k $87.9k $87.9k 0.00% New
98 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 2,0692.1k $84.0k $84.0k 0.00% Added +2.0k +1,979
99 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 2,0312.0k $84.8k $84.8k 0.00% First filing
100 AlphaQuest LLC 0.01% of their portfolio New York, NY 2,0222.0k $82.5k $82.5k 0.01% Reduced -574 -574