SHATTUCK LABS INC STTK
COM · Common Stock · CUSIP 82024L103
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersAustin, TX
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 76.7m as of 2026-04-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $6.43. Options: 1 managers hold calls ($16.1k notional), 0 hold puts (—).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 63 |
| Q4 2022 | 49 |
| Q1 2023 | 50 |
| Q2 2023 | 43 |
| Q3 2023 | 42 |
| Q4 2023 | 58 |
| Q1 2024 | 71 |
| Q2 2024 | 75 |
| Q3 2024 | 79 |
| Q4 2024 | 76 |
| Q1 2025 | 76 |
| Q2 2025 | 62 |
| Q3 2025 | 56 |
| Q4 2025 | 65 |
| Q1 2026 | 84 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 50 | 35 |
| Q3 2024 | 42 | 27 |
| Q4 2024 | 37 | 35 |
| Q1 2025 | 24 | 30 |
| Q2 2025 | 31 | 45 |
| Q3 2025 | 25 | 41 |
| Q4 2025 | 32 | 18 |
| Q1 2026 | 53 | 18 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $28.5k | $0 | 0.00 |
| Q3 2025 | $223.6k | $0 | 0.00 |
| Q4 2025 | $365 | $0 | 0.00 |
| Q1 2026 | $16.1k | $0 | 0.00 |
Biggest buyers
| T. Rowe Price Investment Management, Inc. | Added | +8.0m |
| Prosight Management, LP | Added | +2.6m |
| AMERIPRISE FINANCIAL INC | Added | +894.2k |
| Aberdeen Group plc | Added | +628.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | +567.5k |
| JANE STREET GROUP, LLC | Added | +361.9k |
| DIADEMA PARTNERS LP | New | +293.7k |
| MILLENNIUM MANAGEMENT LLC | Added | +286.3k |
| ALGERT GLOBAL LLC | New | +286.1k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +263.8k |
Biggest sellers
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -1.7m |
| BANK OF AMERICA CORP /DE/ | Reduced | -1.0m |
| 683 Capital Management, LLC | Reduced | -590.0k |
| TWO SIGMA ADVISERS, LP | Sold out | -170.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -143.4k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -121.7k |
| Pathstone Holdings, LLC | Reduced | -83.1k |
| Point72 Asset Management, L.P. | Reduced | -37.2k |
| Squarepoint Ops LLC | Reduced | -33.6k |
| Bank of New York Mellon Corp | Reduced | -20.6k |
Biggest calls
| SIMPLEX TRADING, LLC | Added | $16.1k2.5k shares |
Biggest puts
| None |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| T. Rowe Price Investment Management, Inc. 13G · institution +1.5 pts · filed 2026-08-14 | 15.3% |
ORBIMED ADVISORS LLC
13D · may seek influence
no change · filed 2026-06-15
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer either… Full filing |
10.0% |
| Redmile Group, LLC 13D · may seek influence no change · filed 2026-07-17 | 9.9% |
| Prosight Management, LP 13G · passive investor filed 2025-11-13 | 9.9% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 13G · institution filed 2025-02-12 | 9.8% |
| BlackRock, Inc. 13G · institution +3.5 pts · filed 2026-10-27 | 5.3% |
| Deep Track Capital, LP 13G · passive investor new · filed 2026-06-17 | 5.2% |
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 2 | $82.7k | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 2 | $210.9k | 1 | $166.7k | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 2 | $5.5m | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
None reported in Q1 2026.
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| T. Rowe Price Investment Management, Inc. 0.04% of their portfolio | 9.9m $63.4m | Added +8.0m |
| ORBIMED ADVISORS LLC 0.88% of their portfolio | 6.3m $40.5m | Unchanged |
| Redmile Group, LLC 2.36% of their portfolio | 5.5m $35.6m | Unchanged |
| Prosight Management, LP 5.28% of their portfolio | 5.0m $32.2m | Added +2.6m |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.05% of their portfolio | 4.6m $29.9m | Reduced -1.7m |
| NEXTBio Capital Management LP 9.40% of their portfolio | 3.1m $20.3m | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.3m $14.6m | First filing |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 1.8m $11.5m | Reduced -143.4k |
| CLARK ESTATES INC/NY 2.28% of their portfolio | 1.5m $9.5m | Unchanged |
| PINNACLE ASSOCIATES LTD 0.11% of their portfolio | 1.4m $8.8m | Added +17.6k |
| Aberdeen Group plc 0.01% of their portfolio | 1.2m $7.5m | Added +628.1k |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 1.0m $6.6m | Reduced -37.2k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 905.7k $5.8m | Added +894.2k |
| 683 Capital Management, LLC 0.48% of their portfolio | 800.0k $5.1m | Reduced -590.0k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 763.7k $4.9m | Added +286.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 716.0k $4.6m | Added +567.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 645.7k $4.2m | Added +27.4k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 604.5k $3.9m | Added +263.8k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 581.5k $3.7m | Added +91.6k |
| BlackRock, Inc. 0.00% of their portfolio | 510.8k $3.3m | Added +92.3k |
| S&G Foundation 0.15% of their portfolio | 435.7k $2.8m | First filing |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 415.9k $2.7m | Added +361.9k |
| FMR LLC 0.00% of their portfolio | 392.5k $2.5m | Reduced -100 |
| TD Asset Management Inc 0.00% of their portfolio | 382.6k $2.5m | Added +131.6k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 324.6k $2.1m | First filing |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 316.0k $2.0m | Reduced -121.7k |
| DIADEMA PARTNERS LP 0.78% of their portfolio | 293.7k $1.9m | New |
| ALGERT GLOBAL LLC 0.03% of their portfolio | 286.1k $1.8m | New |
| SPHERA FUNDS MANAGEMENT LTD. 0.31% of their portfolio | 280.8k $1.8m | Added +85.6k |
| STATE STREET CORP 0.00% of their portfolio | 263.8k $1.7m | Added +48.4k |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 228.8k $1.5m | New |
| MORGAN STANLEY 0.00% of their portfolio | 200.1k $1.3m | Added +182.0k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 194.8k $1.3m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 191.4k $1.2m | Added +63.3k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 183.2k $1.2m | Added +103.9k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 155.6k $1.0m | Added +132.4k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 148.0k $951.8k | Added +79.2k |
| XTX Topco Ltd 0.02% of their portfolio | 142.5k $916.1k | Added +117.6k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 142.3k $915.0k | Added +7.2k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 139.3k $895.7k | Added +73.6k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 126.8k $815.3k | Added +88.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 126.1k $810.6k | Reduced -19.4k |
| BARCLAYS PLC 0.00% of their portfolio | 119.9k $770.8k | New |
| HRT FINANCIAL LP 0.00% of their portfolio | 90.7k $583.0k | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 89.8k $577.2k | Reduced -20.6k |
| LBJ Family Wealth Advisors, Ltd. 0.29% of their portfolio | 82.2k $490.0k | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 79.9k $513.9k | Reduced -1.0m |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 79.5k $511.0k | New |
| CITIGROUP INC 0.00% of their portfolio | 75.0k $482.3k | Added +50.2k |
| Persistent Asset Partners Ltd 0.19% of their portfolio | 74.2k $477.3k | New |
| Pathstone Holdings, LLC 0.00% of their portfolio | 74.0k $475.5k | Reduced -83.1k |
| Hillsdale Investment Management Inc. 0.01% of their portfolio | 65.4k $420.5k | New |
| Davis Asset Management, L.P. 0.01% of their portfolio | 48.3k $310.4k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 48.1k $309.5k | Added +30.8k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 42.4k $268.7k | New |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 42.3k $272.0k | Unchanged |
| EP Wealth Advisors, LLC 0.00% of their portfolio | 41.2k $264.7k | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 40.9k $262.9k | Added +20.0k |
| PIPER SANDLER & CO. 0.25% of their portfolio | 39.5k $253.8k | Unchanged |
| Invesco Ltd. 0.00% of their portfolio | 36.9k $237.5k | Added +8.7k |
| UBS Group AG 0.00% of their portfolio | 36.3k $233.3k | Added +23.1k |
| OMERS ADMINISTRATION Corp 0.00% of their portfolio | 33.3k $214.1k | Added +6.8k |
| Squarepoint Ops LLC 0.00% of their portfolio | 31.2k $200.4k | Reduced -33.6k |
| Dynamic Technology Lab Private Ltd 0.03% of their portfolio | 29.6k $190.3k | New |
| CHOREO, LLC 0.00% of their portfolio | 27.3k $130.2k | Unchanged |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 26.3k $169.1k | First filing |
| RITHOLTZ WEALTH MANAGEMENT 0.00% of their portfolio | 26.0k $167.2k | Unchanged |
| Jump Financial, LLC 0.00% of their portfolio | 24.7k $158.7k | New |
| BENJAMIN EDWARDS INC 0.00% of their portfolio | 23.4k $150.5k | New |
| Mallini Complete Financial Planning LLC 0.12% of their portfolio | 22.6k $145.5k | Unchanged |
| Diametric Capital, LP 0.03% of their portfolio | 18.4k $118.5k | New |
| Catalyst Funds Management Pty Ltd 0.02% of their portfolio | 17.9k $115.1k | New |
| Engineers Gate Manager LP 0.00% of their portfolio | 16.1k $103.4k | Added +2.4k |
| Verdad Advisers, LP 0.10% of their portfolio | 13.4k $86.0k | New |
| Creative Planning 0.00% of their portfolio | 12.3k $79.3k | Unchanged |
| Quadrature Capital Ltd 0.00% of their portfolio | 12.1k $78.0k | New |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 11.5k $74.2k | New |
| US BANCORP \DE\ 0.00% of their portfolio | 8.0k $51.5k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 5.6k $36.3k | Added +5.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 248 $1.5k | Reduced -95 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 73 $0 | Added +9 |
| Optiver Holding B.V. 0.00% of their portfolio | 66 $424 | Unchanged |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 50 $322 | Reduced -42 |
| CWM, LLC 0.00% of their portfolio | 39 $251 | Reduced -4 |