Vault-13

SHATTUCK LABS INC STTK

COM · Common Stock · CUSIP 82024L103

56 institutional holders -6 vs Q2 2025
36,388,14736.4m shares reported held*
57.5% of all shares outstanding*
$87.0mreported value*
14 new 11 added 23 reduced 18 sold out net bought ≈ $18.7m (+7.7m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 63.3m as of 2025-10-23, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.39. Options: 3 managers hold calls ($223.6k notional), 0 hold puts (—).

Trends to Q3 2025

Institutional holders

Managers reporting a position, each quarter

050100Q3 22: 63Q4 22: 49Q1 23: 50Q2 23: 43Q3 23: 42Q4 23: 58Q1 24: 71Q2 24: 75Q3 24: 79Q4 24: 76Q1 25: 76Q2 25: 62Q3 25: 5656Q3 22Q2 23Q1 24Q4 24Q3 25
Numbers
QuarterHolders
Q3 202263
Q4 202249
Q1 202350
Q2 202343
Q3 202342
Q4 202358
Q1 202471
Q2 202475
Q3 202479
Q4 202476
Q1 202576
Q2 202562
Q3 202556

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 23: 35 bought or addedQ4 23: 18 cut or sold outQ1 24: 51 bought or addedQ1 24: 23 cut or sold outQ1 24Q2 24: 50 bought or addedQ2 24: 35 cut or sold outQ3 24: 42 bought or addedQ3 24: 27 cut or sold outQ3 24Q4 24: 37 bought or addedQ4 24: 35 cut or sold outQ1 25: 24 bought or addedQ1 25: 30 cut or sold outQ1 25Q2 25: 31 bought or addedQ2 25: 45 cut or sold outQ3 25: 25 bought or addedQ3 25: 41 cut or sold outQ3 25
Numbers
QuarterBought or addedCut or sold out
Q4 20233518
Q1 20245123
Q2 20245035
Q3 20244227
Q4 20243735
Q1 20252430
Q2 20253145
Q3 20252541

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$100k$200k$300kQ4 24 calls: $0Q4 24 puts: $0Q4 24P/C —Q1 25 calls: $95Q1 25 puts: $0Q1 25P/C 0.00Q2 25 calls: $28.5kQ2 25 puts: $0Q2 25P/C 0.00Q3 25 calls: $223.6kQ3 25 puts: $0Q3 25P/C 0.00
Numbers
QuarterCallsPutsP/C
Q4 2024$0$0—
Q1 2025$95$00.00
Q2 2025$28.5k$00.00
Q3 2025$223.6k$00.00

Biggest buyers

ORBIMED ADVISORS LLC New +6,306,127+6.3m
ADAGE CAPITAL PARTNERS GP, L.L.C. Added +1,631,127+1.6m
BANK OF AMERICA CORP /DE/ Added +1,094,997+1.1m
MARSHALL WACE, LLP New +656,653+656.7k
683 Capital Management, LLC Added +437,216+437.2k
TWO SIGMA INVESTMENTS, LP Added +331,664+331.7k
RENAISSANCE TECHNOLOGIES LLC Added +178,767+178.8k
TWO SIGMA ADVISERS, LP Added +98,677+98.7k
Aberdeen Group plc New +94,504+94.5k
LBJ Family Wealth Advisors, Ltd. New +82,177+82.2k

Biggest sellers

Prosight Management, LP Reduced -1,187,740-1.2m
BlackRock, Inc. Reduced -470,096-470.1k
GOLDMAN SACHS GROUP INC Reduced -308,454-308.5k
UBS Group AG Reduced -266,938-266.9k
JANE STREET GROUP, LLC Reduced -190,624-190.6k
Pathstone Holdings, LLC Reduced -157,083-157.1k
MILLENNIUM MANAGEMENT LLC Reduced -152,355-152.4k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced -128,212-128.2k
Y-Intercept (Hong Kong) Ltd Sold out -123,172-123.2k
ADAR1 Capital Management, LLC Sold out -102,948-102.9k

Biggest calls

GROUP ONE TRADING LLC New $119.5k50.0k shares
CITADEL ADVISORS LLC Reduced $53.1k22.2k shares
SIMPLEX TRADING, LLC New $51.0k21.6k shares

Biggest puts

None

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
T. Rowe Price Investment Management, Inc. 13G · institution +1.5 pts · filed 2026-08-14 15.3% +1.5 pts 13.4m≈ $93.2m 2026-08-14
ORBIMED ADVISORS LLC 13D · may seek influence no change · filed 2026-06-15
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer either… Full filing
10.0% no change 9.0m≈ $62.6m 2026-06-15
Redmile Group, LLC 13D · may seek influence no change · filed 2026-07-17 9.9% no change 10.0m≈ $69.5m 2026-07-17
Prosight Management, LP 13G · passive investor filed 2025-11-13 9.9% 6.5m≈ $45.4m 2025-11-13
ADAGE CAPITAL PARTNERS GP, L.L.C. 13G · institution filed 2025-02-12 9.8% 4.7m≈ $32.4m 2025-02-12
BlackRock, Inc. 13G · institution +3.5 pts · filed 2026-10-27 5.3% +3.5 pts 5.3m≈ $37.1m 2026-10-27
Deep Track Capital, LP 13G · passive investor new · filed 2026-06-17 5.2% new 5.0m≈ $34.7m 2026-06-17

Insider purchases and sales in Q3 2025

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
202Q4 23: 0 buyingQ4 23: 0 sellingQ1 24: 0 buyingQ1 24: 2 sellingQ1 24Q2 24: 2 buyingQ2 24: 0 sellingQ3 24: 0 buyingQ3 24: 0 sellingQ3 24Q4 24: 2 buyingQ4 24: 1 sellingQ1 25: 0 buyingQ1 25: 0 sellingQ1 25Q2 25: 0 buyingQ2 25: 0 sellingQ3 25: 2 buyingQ3 25: 0 sellingQ3 25
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20230—0——
Q1 20240—2$418.5k$418.5k
Q2 20242$82.7k0——
Q3 20240—0——
Q4 20242$210.9k1$166.7k—
Q1 20250—0——
Q2 20250—0——
Q3 20252$5.5m0——
DateInsiderTradeSharesPrice ValueTheir holding
2025-08-25 Ashiya Mona Director · See Footnote Bought 6,306,127 $0.87 $5.5m6.3m shares new
2025-08-25 ORBIMED ADVISORS LLC +2 Director · See Footnote Bought 6,306,127 $0.87 $5.5m6.3m shares new

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q3 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 ORBIMED ADVISORS LLC 0.36% of their portfolio New York, NY 6,306,1276.3m $15.1m $15.1m 0.36% New
2 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio Boston, MA 6,306,1276.3m $15.1m $15.1m 0.02% Added +1.6m +1,631,127
3 Redmile Group, LLC 1.29% of their portfolio LARKSPUR, CA 5,539,7245.5m $13.2m $13.2m 1.29% Unchanged
4 Prosight Management, LP 3.13% of their portfolio DALLAS, TX 5,451,1955.5m $13.0m $13.0m 3.13% Reduced -1.2m -1,187,740
5 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 2,128,4012.1m $5.1m $5.1m 0.00% Reduced -19.8k -19,773
6 683 Capital Management, LLC 0.33% of their portfolio NEW YORK, NY 1,532,2161.5m $3.7m $3.7m 0.33% Added +437.2k +437,216
7 CLARK ESTATES INC/NY 0.81% of their portfolio NEW YORK, NY 1,475,6481.5m $3.5m $3.5m 0.81% Unchanged
8 PINNACLE ASSOCIATES LTD 0.04% of their portfolio NEW YORK, NY 1,388,7231.4m $3.3m $3.3m 0.04% Added +25.0k +25,000
9 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 1,131,8881.1m $2.7m $2.7m 0.00% Added +1.1m +1,094,997
10 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 690,901690.9k $1.7m $1.7m 0.00% Reduced -152.4k -152,355
11 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 656,653656.7k $1.6m $1.6m 0.00% New
12 TAKEDA PHARMACEUTICAL CO LTD 7.53% of their portfolio Tokyo, M0 515,619515.6k $1.2m $1.2m 7.53% Unchanged
13 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 467,959468.0k $1.1m $1.1m 0.00% Unchanged
14 BlackRock, Inc. 0.00% of their portfolio New York, NY 411,292411.3k $983.0k $983.0k 0.00% Reduced -470.1k -470,096
15 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 408,598408.6k $976.5k $976.5k 0.00% Added +331.7k +331,664
16 ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio Boston, MA 329,288329.3k $785.0k $785.0k 0.00% Added +68.3k +68,330
17 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 216,867216.9k $518.3k $518.3k 0.00% Added +178.8k +178,767
18 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 176,718176.7k $422.4k $422.4k 0.00% Unchanged
19 Pathstone Holdings, LLC 0.00% of their portfolio ENGLEWOOD, NJ 157,083157.1k $375.4k $375.4k 0.00% Reduced -157.1k -157,083
20 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 112,677112.7k $269.3k $269.3k 0.00% Added +98.7k +98,677
21 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 110,394110.4k $263.8k $263.8k 0.00% Unchanged
22 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 99,04799.0k $236.7k $236.7k 0.00% Reduced -190.6k -190,624
23 Aberdeen Group plc 0.00% of their portfolio EDINBURGH, X0 94,50494.5k $225.9k $225.9k 0.00% New
24 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 91,27291.3k $218.1k $218.1k 0.00% Reduced -19.7k -19,711
25 LBJ Family Wealth Advisors, Ltd. 0.11% of their portfolio AUSTIN, TX 82,17782.2k $196.0k $196.0k 0.11% New
26 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 68,11668.1k $162.8k $162.8k 0.00% Reduced -128.2k -128,212
27 Keel Point, LLC 0.01% of their portfolio HUNTSVILLE, AL 46,17346.2k $110.4k $110.4k 0.01% New
28 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio HOUSTON, TX 42,30042.3k $101.1k $101.1k 0.00% Reduced -50.0k -50,000
29 PIPER SANDLER & CO. 0.07% of their portfolio MINNEAPOLIS, MN 39,46739.5k $94.3k $94.3k 0.07% Unchanged
30 CHOREO, LLC 0.00% of their portfolio ROCKFORD, IL 27,25127.3k $53.6k $53.6k 0.00% Reduced -68 -68
31 XTX Topco Ltd 0.00% of their portfolio LONDON, X0 26,22626.2k $62.7k $62.7k 0.00% New
32 RITHOLTZ WEALTH MANAGEMENT 0.00% of their portfolio NEW YORK, NY 26,00026.0k $62.1k $62.1k 0.00% Unchanged
33 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 20,88120.9k $49.9k $49.9k 0.00% Reduced -25 -25
34 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 19,26019.3k $46.0k $46.0k 0.00% New
35 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 17,70017.7k $42.3k $42.3k 0.00% New
36 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 16,80016.8k $40.2k $40.2k 0.00% Reduced -308.5k -308,454
37 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 16,65116.7k $39.8k $39.8k 0.00% Reduced -7.4k -7,437
38 Virtu Financial LLC 0.00% of their portfolio New York, NY 16,05416.1k $38.0k $38.0k 0.00% New
39 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 15,95116.0k $38.1k $38.1k 0.00% Reduced -39.4k -39,429
40 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 15,10815.1k $36.1k $36.1k 0.00% Added +6.5k +6,520
41 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 14,52114.5k $34.0k $34.0k 0.00% Added +9.7k +9,665
42 Point72 Asia (Singapore) Pte. Ltd. 0.01% of their portfolio SINGAPORE, U0 14,45414.5k $34.5k $34.5k 0.01% Reduced -14.5k -14,454
43 Engineers Gate Manager LP 0.00% of their portfolio NEW YORK, NY 13,67013.7k $32.7k $32.7k 0.00% Reduced -156 -156
44 Creative Planning 0.00% of their portfolio OVERLAND PARK, KS 12,33512.3k $29.5k $29.5k 0.00% New
45 Turtle Creek Wealth Advisors, LLC 0.00% of their portfolio DALLAS, TX 12,23512.2k $29.2k $29.2k 0.00% New
46 AssuredPartners Investment Advisors, LLC 0.01% of their portfolio Tampa, FL 10,00010.0k $23.9k $23.9k 0.01% New
47 Cubist Systematic Strategies, LLC 0.00% of their portfolio STAMFORD, CT 8,8638.9k $21.2k $21.2k 0.00% Added +5.1k +5,051
48 FMR LLC 0.00% of their portfolio BOSTON, MA 3,3673.4k $8.0k $8.0k 0.00% Reduced -5.1k -5,071
49 UBS Group AG 0.00% of their portfolio ZURICH, V8 1,4331.4k $3.4k $3.4k 0.00% Reduced -266.9k -266,938
50 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 958958 $2.3k $2.3k 0.00% Reduced -2.2k -2,213
51 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 606606 $1.4k $1.4k 0.00% Reduced -265 -265
52 Point72 (DIFC) Ltd 0.00% of their portfolio DUBAI, C0 370370 $884 $884 0.00% Reduced -720 -720
53 CWM, LLC 0.00% of their portfolio OMAHA, NE 127127 $0 $0 0.00% Reduced -2.9k -2,862
54 SBI Securities Co., Ltd. 0.00% of their portfolio TOKYO, M0 9292 $220 $220 0.00% Reduced -50 -50
55 Optiver Holding B.V. 0.00% of their portfolio AMSTERDAM, P7 6666 $158 $158 0.00% New
56 Arax Advisory Partners 0.00% of their portfolio NEW YORK, NY 1414 $33 $33 0.00% New