SHATTUCK LABS INC STTK
COM · Common Stock · CUSIP 82024L103
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersAustin, TX
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 47.9m as of 2025-08-07, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $0.79. Options: 2 managers hold calls ($28.5k notional), 1 hold puts ($0).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 63 |
| Q4 2022 | 49 |
| Q1 2023 | 50 |
| Q2 2023 | 43 |
| Q3 2023 | 42 |
| Q4 2023 | 58 |
| Q1 2024 | 71 |
| Q2 2024 | 75 |
| Q3 2024 | 79 |
| Q4 2024 | 76 |
| Q1 2025 | 76 |
| Q2 2025 | 62 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 7 | 21 |
| Q4 2023 | 35 | 18 |
| Q1 2024 | 51 | 23 |
| Q2 2024 | 50 | 35 |
| Q3 2024 | 42 | 27 |
| Q4 2024 | 37 | 35 |
| Q1 2025 | 24 | 30 |
| Q2 2025 | 31 | 45 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $304.0k | $4.2k | 0.01 |
| Q4 2024 | $0 | $0 | — |
| Q1 2025 | $95 | $0 | 0.00 |
| Q2 2025 | $28.5k | $0 | 0.00 |
Biggest buyers
| MILLENNIUM MANAGEMENT LLC | Added | +540.7k |
| JANE STREET GROUP, LLC | Added | +278.6k |
| GOLDMAN SACHS GROUP INC | Added | +222.9k |
| Pathstone Holdings, LLC | Added | +157.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | +144.9k |
| Y-Intercept (Hong Kong) Ltd | New | +123.2k |
| UBS Group AG | Added | +117.2k |
| PINNACLE ASSOCIATES LTD | Added | +64.0k |
| Qube Research & Technologies Ltd | New | +55.4k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | Added | +55.0k |
Biggest sellers
| BlackRock, Inc. | Reduced | -1.7m |
| STATE STREET CORP | Reduced | -606.7k |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | -465.5k |
| VANGUARD GROUP INC | Reduced | -252.4k |
| NORTHERN TRUST CORP | Reduced | -236.2k |
| DEUTSCHE BANK AG\ | Sold out | -116.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | Reduced | -93.2k |
| Bank of New York Mellon Corp | Reduced | -82.6k |
| LBJ Family Wealth Advisors, Ltd. | Sold out | -82.2k |
| TWO SIGMA ADVISERS, LP | Reduced | -73.1k |
Biggest calls
| CITADEL ADVISORS LLC | New | $28.5k36.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| T. Rowe Price Investment Management, Inc. 13G · institution +1.5 pts · filed 2026-08-14 | 15.3% |
ORBIMED ADVISORS LLC
13D · may seek influence
no change · filed 2026-06-15
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer either… Full filing |
10.0% |
| Redmile Group, LLC 13D · may seek influence no change · filed 2026-07-17 | 9.9% |
| Prosight Management, LP 13G · passive investor filed 2025-11-13 | 9.9% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 13G · institution filed 2025-02-12 | 9.8% |
| BlackRock, Inc. 13G · institution +3.5 pts · filed 2026-10-27 | 5.3% |
| Deep Track Capital, LP 13G · passive investor new · filed 2026-06-17 | 5.2% |
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 2 | $418.5k | $418.5k |
| Q2 2024 | 2 | $82.7k | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 2 | $210.9k | 1 | $166.7k | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
None reported in Q2 2025.
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| Prosight Management, LP 1.28% of their portfolio | 6.6m $5.3m | Unchanged |
| Redmile Group, LLC 0.47% of their portfolio | 5.5m $4.4m | Unchanged |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 4.7m $3.7m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.1m $1.7m | Reduced -252.4k |
| CLARK ESTATES INC/NY 0.26% of their portfolio | 1.5m $1.2m | Unchanged |
| PINNACLE ASSOCIATES LTD 0.02% of their portfolio | 1.4m $1.1m | Added +64.0k |
| 683 Capital Management, LLC 0.09% of their portfolio | 1.1m $867.0k | Added +45.0k |
| BlackRock, Inc. 0.00% of their portfolio | 881.4k $697.9k | Reduced -1.7m |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 843.3k $667.7k | Added +540.7k |
| TAKEDA PHARMACEUTICAL CO LTD 2.09% of their portfolio | 515.6k $408.3k | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 468.0k $370.7k | Reduced -465.5k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 325.3k $257.5k | Added +222.9k |
| Pathstone Holdings, LLC 0.00% of their portfolio | 314.2k $205.9k | Added +157.1k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 289.7k $229.4k | Added +278.6k |
| UBS Group AG 0.00% of their portfolio | 268.4k $212.5k | Added +117.2k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 261.0k $205.0k | Added +3.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 196.3k $155.5k | Added +144.9k |
| STATE STREET CORP 0.00% of their portfolio | 176.7k $139.9k | Reduced -606.7k |
| Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio | 123.2k $97.5k | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 111.0k $87.9k | Reduced -236.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 110.4k $87.4k | Reduced -82.6k |
| ADAR1 Capital Management, LLC 0.01% of their portfolio | 102.9k $81.5k | Added +792 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 92.3k $73.1k | Added +55.0k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 76.9k $60.9k | Reduced -8.3k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 55.4k $43.9k | New |
| EP Wealth Advisors, LLC 0.00% of their portfolio | 41.2k $32.6k | Unchanged |
| PIPER SANDLER & CO. 0.02% of their portfolio | 39.5k $31.2k | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 38.1k $30.2k | Added +10.1k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 38.0k $30.1k | Reduced -5.2k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 36.9k $29.2k | Reduced -62.9k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 35.8k $28.3k | Reduced -49.9k |
| Jain Global LLC 0.00% of their portfolio | 34.5k $27.3k | New |
| Point72 Asia (Singapore) Pte. Ltd. 0.00% of their portfolio | 28.9k $22.9k | New |
| CHOREO, LLC 0.00% of their portfolio | 27.3k $23.4k | Added +8.4k |
| RITHOLTZ WEALTH MANAGEMENT 0.00% of their portfolio | 26.0k $20.6k | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 24.1k $19.1k | Reduced -56.3k |
| Summit Trail Advisors, LLC 0.00% of their portfolio | 23.6k $18.7k | Added +1.6k |
| Mallini Complete Financial Planning LLC 0.00% of their portfolio | 22.6k $1.8k | Added +3.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 20.9k $16.6k | Reduced -93.2k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 16.9k $13.4k | Added +8.5k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 16.1k $12.9k | New |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 14.0k $11.1k | Reduced -73.1k |
| Engineers Gate Manager LP 0.00% of their portfolio | 13.8k $10.9k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 8.6k $6.8k | Reduced -20.0k |
| FMR LLC 0.00% of their portfolio | 8.4k $6.7k | Reduced -1.8k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 4.9k $4.0k | Added +255 |
| Cubist Systematic Strategies, LLC 0.00% of their portfolio | 3.8k $3.0k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 3.2k $2.5k | Added +456 |
| CWM, LLC 0.00% of their portfolio | 3.0k $2.0k | Reduced -268 |
| Briaud Financial Planning Inc 0.00% of their portfolio | 2.2k $1.0k | New |
| BARCLAYS PLC 0.00% of their portfolio | 2.1k $1.7k | Reduced -48.8k |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 1.2k $0 | New |
| Point72 (DIFC) Ltd 0.00% of their portfolio | 1.1k $863 | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 871 $690 | Reduced -35.7k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 851 $674 | Reduced -19.4k |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 686 $543 | Reduced -88 |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 250 $198 | New |
| Clearstead Advisors, LLC 0.00% of their portfolio | 155 $123 | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 142 $112 | Unchanged |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 112 $89 | Added +104 |
| True Wealth Design, LLC 0.00% of their portfolio | 46 $37 | Added +30 |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. — of their portfolio | 0 $0 | Unchanged |