Vault-13

MIRATI THERAPEUTICS INC MRTX

COM · Common Stock · CUSIP 60468T105 · ISIN US60468T1051

223 institutional holders -10 vs Q4 2022
64,152,75464.2m shares reported held*
$2.4bnreported value*
31 new 88 added 65 reduced 39 sold out net sold ≈ $44.2m (-1.2m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($3.3m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $37.16. Options: 16 managers hold calls ($16.7m notional), 11 hold puts ($10.6m).

Trends to Q1 2023

Institutional holders

Managers reporting a position, each quarter

0100200300Q3 22: 244Q4 22: 233Q1 23: 223223Q3 22Q4 22Q1 23
Numbers
QuarterHolders
Q3 2022244
Q4 2022233
Q1 2023223

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 133 bought or addedQ4 22: 118 cut or sold outQ4 22Q1 23: 119 bought or addedQ1 23: 104 cut or sold outQ1 23
Numbers
QuarterBought or addedCut or sold out
Q4 2022133118
Q1 2023119104

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$25m$50m$75m$100mQ3 22 calls: $71.0mQ3 22 puts: $87.9mQ3 22P/C 1.24Q4 22 calls: $86.2mQ4 22 puts: $34.1mQ4 22P/C 0.40Q1 23 calls: $16.7mQ1 23 puts: $10.6mQ1 23P/C 0.64
Numbers
QuarterCallsPutsP/C
Q3 2022$71.0m$87.9m1.24
Q4 2022$86.2m$34.1m0.40
Q1 2023$16.7m$10.6m0.64

Biggest buyers

BlackRock Inc. Added +573,957+574.0k
MARSHALL WACE, LLP New +552,614+552.6k
VOLORIDGE INVESTMENT MANAGEMENT, LLC Added +524,038+524.0k
MORGAN STANLEY Added +361,742+361.7k
PRICE T ROWE ASSOCIATES INC /MD/ Added +354,213+354.2k
PFM Health Sciences, LP New +318,948+318.9k
Kynam Capital Management, LP Added +308,695+308.7k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added +294,921+294.9k
Rock Springs Capital Management LP Added +260,237+260.2k
ARMISTICE CAPITAL, LLC Added +204,000+204.0k

Biggest sellers

AMERIPRISE FINANCIAL INC Sold out -637,130-637.1k
PERCEPTIVE ADVISORS LLC Reduced -617,291-617.3k
California Public Employees Retirement System Reduced -583,165-583.2k
JANUS HENDERSON GROUP PLC Reduced -508,471-508.5k
Cormorant Asset Management, LP Sold out -400,000-400.0k
Woodline Partners LP Reduced -370,617-370.6k
ORBIMED ADVISORS LLC Reduced -370,042-370.0k
FMR LLC Reduced -329,862-329.9k
WELLINGTON MANAGEMENT GROUP LLP Reduced -320,243-320.2k
BANK OF NOVA SCOTIA Reduced -313,628-313.6k

Biggest calls

ORBIMED ADVISORS LLC New $5.6m150.0k shares
JANE STREET GROUP, LLC Added $2.4m65.6k shares
Islet Management, LP New $1.9m50.0k shares
GROUP ONE TRADING LLC Reduced $1.5m40.5k shares
MILLENNIUM MANAGEMENT LLC Added $1.5m40.4k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $1.5m39.1k shares
SIMPLEX TRADING, LLC Reduced $829.0k22.3k shares
NOMURA HOLDINGS INC New $524.2k14.1k shares
Corient Private Wealth LP New $371.8k10.0k shares
CITADEL ADVISORS LLC Reduced $308.6k8.3k shares

Biggest puts

CITADEL ADVISORS LLC Reduced $2.6m70.6k shares
GROUP ONE TRADING LLC Reduced $1.8m49.4k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $1.5m39.1k shares
SIMPLEX TRADING, LLC Reduced $1.4m37.3k shares
Jefferies Financial Group Inc. Reduced $1.0m27.2k shares
UBS Group AG New $951.8k25.6k shares
CITIGROUP INC New $929.5k25.0k shares
JANE STREET GROUP, LLC Reduced $211.9k5.7k shares
Walleye Trading LLC New $171.0k4.6k shares
Walleye Capital LLC New $63.2k1.7k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q1 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Avoro Capital Advisors LLC 3.06% of their portfolio NEW YORK, NY 5,555,5555.6m $206.6m $206.6m 3.06% Unchanged
2 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 5,049,3755.0m $187.7m $187.7m 0.00% Added +75.5k +75,487
3 ARMISTICE CAPITAL, LLC 3.19% of their portfolio NEW YORK, NY 3,692,0003.7m $137.3m $137.3m 3.19% Added +204.0k +204,000
4 RTW INVESTMENTS, LP 2.82% of their portfolio NEW YORK, NY 3,643,1143.6m $135.5m $135.5m 2.82% Unchanged
5 BlackRock Inc. 0.00% of their portfolio New York, NY 3,236,8793.2m $120.3m $120.3m 0.00% Added +574.0k +573,957
6 Aviva Holdings Ltd. 81.37% of their portfolio NEW PROVIDENCE, C5 3,135,9663.1m $116.6m $116.6m 81.37% Unchanged
7 WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio Boston, MA 2,696,0922.7m $100.2m $100.2m 0.02% Reduced -320.2k -320,243
8 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 2,309,8202.3m $85.9m $85.9m 0.00% Reduced -235.8k -235,756
9 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 2,051,4532.1m $76.3m $76.3m 0.01% Added +361.7k +361,742
10 Boxer Capital, LLC 3.65% of their portfolio San Diego, CA 2,000,0002.0m $74.4m $74.4m 3.65% Unchanged
11 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 1,770,9411.8m $65.8m $65.8m 0.01% Added +354.2k +354,213
12 PERCEPTIVE ADVISORS LLC 1.73% of their portfolio NEW YORK, NY 1,574,1341.6m $58.5m $58.5m 1.73% Reduced -617.3k -617,291
13 Artal Group S.A. 3.40% of their portfolio LUXEMBOURG, N4 1,537,7091.5m $57.2m $57.2m 3.40% Reduced -295.0k -295,049
14 BAKER BROS. ADVISORS LP 0.29% of their portfolio NEW YORK, NY 1,409,7841.4m $52.4m $52.4m 0.29% Unchanged
15 Camber Capital Management LP 1.78% of their portfolio BOSTON, MA 1,400,0001.4m $52.1m $52.1m 1.78% Unchanged
16 Paradigm Biocapital Advisors LP 4.92% of their portfolio NEW YORK, NY 1,396,7791.4m $51.9m $51.9m 4.92% Added +128.8k +128,809
17 Rock Springs Capital Management LP 0.95% of their portfolio Baltimore, MD 1,065,2611.1m $39.6m $39.6m 0.95% Added +260.2k +260,237
18 ORBIMED ADVISORS LLC 0.67% of their portfolio New York, NY 913,650913.6k $34.0m $34.0m 0.67% Reduced -370.0k -370,042
19 Candriam S.C.A. 0.18% of their portfolio STRASSEN, N4 764,265764.3k $26.2m $26.2m 0.18% Reduced -3.3k -3,331
20 Octagon Capital Advisors LP 4.02% of their portfolio NEW YORK, NY 750,000750.0k $27.9m $27.9m 4.02% Unchanged
21 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 735,288735.3k $27.3m $27.3m 0.00% Added +27.9k +27,943
22 Fiera Capital Corp 0.08% of their portfolio MONTREAL, A8 709,527709.5k $26.4m $26.4m 0.08% Added +16.9k +16,870
23 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.13% of their portfolio JUPITER, FL 678,658678.7k $25.2m $25.2m 0.13% Added +524.0k +524,038
24 NORGES BANK 0.01% of their portfolio OSLO, Q8 657,238657.2k $24.4m $24.4m 0.01% Added +181.2k +181,246
25 FRANKLIN RESOURCES INC 0.01% of their portfolio San Mateo, CA 652,368652.4k $24.3m $24.3m 0.01% Reduced -84.4k -84,400
26 Point72 Asset Management, L.P. 0.09% of their portfolio STAMFORD, CT 645,500645.5k $24.0m $24.0m 0.09% Reduced -108.1k -108,100
27 MARSHALL WACE, LLP 0.05% of their portfolio LONDON, X0 552,614552.6k $20.5m $20.5m 0.05% New
28 CREDIT SUISSE AG/ 0.02% of their portfolio ZURICH, V8 523,367523.4k $19.5m $19.5m 0.02% Added +2.3k +2,283
29 Casdin Capital, LLC 1.57% of their portfolio New York, NY 510,000510.0k $19.0m $19.0m 1.57% Added +35.0k +35,000
30 Kynam Capital Management, LP 2.40% of their portfolio PRINCETON, NJ 499,853499.9k $18.6m $18.6m 2.40% Added +308.7k +308,695
31 BRAIDWELL LP 0.55% of their portfolio STAMFORD, CT 452,000452.0k $16.8m $16.8m 0.55% Added +38.4k +38,400
32 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 430,494430.5k $16.0m $16.0m 0.00% Reduced -1.5k -1,469
33 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 386,250386.2k $14.4m $14.4m 0.00% Added +83.1k +83,132
34 EVENTIDE ASSET MANAGEMENT, LLC 0.25% of their portfolio Boston, MA 371,102371.1k $13.8m $13.8m 0.25% Added +167.5k +167,502
35 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.02% of their portfolio BALA CYNWYD, PA 362,612362.6k $13.5m $13.5m 0.02% Added +294.9k +294,921
36 FMR LLC 0.00% of their portfolio BOSTON, MA 356,166356.2k $13.2m $13.2m 0.00% Reduced -329.9k -329,862
37 NATIONAL BANK OF CANADA /FI/ 0.03% of their portfolio MONTREAL, A8 341,200341.2k $12.7m $12.7m 0.03% Reduced -26.1k -26,100
38 PFM Health Sciences, LP 0.55% of their portfolio SAN FRANCISCO, CA 318,948318.9k $11.9m $11.9m 0.55% New
39 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 304,594304.6k $11.3m $11.3m 0.00% Added +13.7k +13,735
40 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio NEW YORK, NY 302,821302.8k $11.3m $11.3m 0.01% Added +62.9k +62,919
41 Woodline Partners LP 0.14% of their portfolio San Francisco, CA 266,100266.1k $9.9m $9.9m 0.14% Reduced -370.6k -370,617
42 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 260,409260.4k $9.7m $9.7m 0.00% Added +23.1k +23,135
43 Assenagon Asset Management S.A. 0.04% of their portfolio SENNINGERBERG, N4 255,960256.0k $9.5m $9.5m 0.04% Added +86.2k +86,175
44 D. E. Shaw & Co., Inc. 0.01% of their portfolio New York, NY 245,586245.6k $9.1m $9.1m 0.01% Added +32.3k +32,285
45 INTERNATIONAL BIOTECHNOLOGY TRUST PLC 2.53% of their portfolio London, X0 244,000244.0k $9.1m $9.1m 2.53% Unchanged
46 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 238,855238.9k $8.9m $8.9m 0.00% Added +11.5k +11,534
47 Allspring Global Investments Holdings, LLC 0.01% of their portfolio CHARLOTTE, NC 233,039233.0k $8.7m $8.7m 0.01% Reduced -5.2k -5,243
48 NEW YORK STATE COMMON RETIREMENT FUND 0.01% of their portfolio ALBANY, NY 232,217232.2k $8.6m $8.6m 0.01% Added +835 +835
49 Rhenman & Partners Asset Management AB 0.87% of their portfolio Stockholm, V7 215,000215.0k $7.9m $7.9m 0.87% Reduced -85.0k -85,000
50 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 203,607203.6k $7.6m $7.6m 0.00% Added +9.6k +9,574
51 ORACLE INVESTMENT MANAGEMENT INC 7.38% of their portfolio GREENWICH, CT 201,400201.4k $7.5m $7.5m 7.38% Added +130.9k +130,947
52 JACOBS LEVY EQUITY MANAGEMENT, INC 0.04% of their portfolio FLORHAM PARK, NJ 184,716184.7k $6.9m $6.9m 0.04% Added +142.7k +142,694
53 EDMOND DE ROTHSCHILD HOLDING S.A. 0.16% of their portfolio CHAMBESY, V8 184,060184.1k $6.8m $6.8m 0.16% Added +15.0k +15,000
54 Walleye Capital LLC 0.14% of their portfolio NEW YORK, NY 182,480182.5k $6.8m $6.8m 0.14% Added +140.4k +140,382
55 Rafferty Asset Management, LLC 0.04% of their portfolio New York, NY 173,516173.5k $6.5m $6.5m 0.04% Reduced -19.6k -19,557
56 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 170,264170.3k $6.3m $6.3m 0.00% Added +1.3k +1,308
57 ExodusPoint Capital Management, LP 0.07% of their portfolio NEW YORK, NY 163,742163.7k $6.1m $6.1m 0.07% Added +144.3k +144,328
58 CITIGROUP INC 0.01% of their portfolio NEW YORK, NY 158,993159.0k $5.9m $5.9m 0.01% Added +36.3k +36,279
59 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 155,359155.4k $5.8m $5.8m 0.00% Reduced -278.2k -278,217
60 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 149,128149.1k $5.5m $5.5m 0.01% Reduced -41.1k -41,092
61 BARCLAYS PLC 0.01% of their portfolio LONDON, X0 141,860141.9k $5.3m $5.3m 0.01% Reduced -86.6k -86,565
62 Ghost Tree Capital, LLC 1.97% of their portfolio NEW YORK, NY 140,000140.0k $5.2m $5.2m 1.97% Reduced -60.0k -60,000
63 Connor, Clark & Lunn Investment Management Ltd. 0.03% of their portfolio VANCOUVER, A1 136,486136.5k $5.1m $5.1m 0.03% New
64 Granahan Investment Management, LLC 0.15% of their portfolio WALTHAM, MA 129,090129.1k $4.8m $4.8m 0.15% Added +37.2k +37,190
65 SECTORAL ASSET MANAGEMENT INC 0.92% of their portfolio MONTREAL, A8 128,406128.4k $4.8m $4.8m 0.92% Added +61.6k +61,560
66 TWINBEECH CAPITAL LP 0.10% of their portfolio PURCHASE, NY 126,758126.8k $4.7m $4.7m 0.10% Added +89.8k +89,808
67 Lombard Odier Asset Management (Switzerland) SA 0.37% of their portfolio PETIT-LANCY, V8 112,952113.0k $4.2m $4.2m 0.37% Added +43.0k +42,999
68 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 101,966102.0k $3.8m $3.8m 0.00% Added +28.3k +28,324
69 BANK OF NOVA SCOTIA 0.01% of their portfolio TORONTO, A6 99,70599.7k $3.7m $3.7m 0.01% Reduced -313.6k -313,628
70 NOMURA HOLDINGS INC 0.03% of their portfolio TOKYO, M0 95,62095.6k $3.6m $3.6m 0.03% Added +41.1k +41,070
71 Skandinaviska Enskilda Banken AB (publ) 0.02% of their portfolio STOCKHOLM, V7 94,91294.9k $3.5m $3.5m 0.02% Reduced -583 -583
72 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 90,64490.6k $3.4m $3.4m 0.00% Reduced -29.9k -29,859
73 Swiss National Bank 0.00% of their portfolio ZURICH, V8 87,00087.0k $3.2m $3.2m 0.00% Reduced -7.0k -7,000
74 UBS Group AG 0.00% of their portfolio ZURICH, V8 81,43281.4k $3.0m $3.0m 0.00% Reduced -58.3k -58,300
75 HRT FINANCIAL LP 0.04% of their portfolio NEW YORK, NY 81,30681.3k $3.0m $3.0m 0.04% New
76 Handelsbanken Fonder AB 0.02% of their portfolio STOCKHOLM, V7 75,60075.6k $2.8m $2.8m 0.02% Unchanged
77 DAFNA Capital Management LLC 0.82% of their portfolio LOS ANGELES, CA 73,60073.6k $2.7m $2.7m 0.82% Unchanged
78 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 71,64371.6k $2.7m $2.7m 0.00% Added +40.3k +40,275
79 Thrivent Financial for Lutherans 0.01% of their portfolio Minneapolis, MN 71,59971.6k $2.7m $2.7m 0.01% Reduced -61.7k -61,734
80 California Public Employees Retirement System 0.00% of their portfolio Sacramento, CA 69,45469.5k $2.6m $2.6m 0.00% Reduced -583.2k -583,165
81 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 67,40567.4k $2.5m $2.5m 0.00% Added +13.3k +13,300
82 Cubist Systematic Strategies, LLC 0.02% of their portfolio STAMFORD, CT 67,13267.1k $2.5m $2.5m 0.02% Added +56.9k +56,929
83 BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio PARIS, I0 65,63565.6k $2.4m $2.4m 0.01% Reduced -285.9k -285,912
84 Tekla Capital Management LLC 0.09% of their portfolio Boston, MA 65,49065.5k $2.4m $2.4m 0.09% Unchanged
85 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 64,27464.3k $2.4m $2.4m 0.00% Added +4.2k +4,248
86 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.01% of their portfolio TALLAHASSEE, FL 63,87263.9k $2.4m $2.4m 0.01% Unchanged
87 ALGERT GLOBAL LLC 0.11% of their portfolio SAN FRANCISCO, CA 63,22463.2k $2.4m $2.4m 0.11% Added +34.1k +34,079
88 Balyasny Asset Management L.P. 0.01% of their portfolio Chicago, IL 60,72460.7k $2.3m $2.3m 0.01% Added +15.2k +15,183
89 MACQUARIE GROUP LTD 0.00% of their portfolio Sydney, NSW 2000, C3 60,00060.0k $2.2m $2.2m 0.00% Unchanged
90 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 59,84859.8k $2.2m $2.2m 0.00% Added +16.8k +16,842
91 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 52,11752.1k $1.9m $1.9m 0.00% Added +348 +348
92 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 51,37951.4k $1.9m $1.9m 0.00% Added +13.6k +13,559
93 State of New Jersey Common Pension Fund D 0.01% of their portfolio TRENTON, NJ 50,43450.4k $1.9m $1.9m 0.01% Added +23.4k +23,446
94 Jefferies Financial Group Inc. 0.04% of their portfolio NEW YORK, NY 50,42050.4k $1.9m $1.9m 0.04% Added +18.3k +18,279
95 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 50,21450.2k $1.9m $1.9m 0.00% New
96 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 49,76249.8k $1.9m $1.9m 0.00% Added +18.4k +18,410
97 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 48,43748.4k $1.8m $1.8m 0.00% Reduced -817 -817
98 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 47,76247.8k $1.8m $1.8m 0.00% Reduced -244.9k -244,936
99 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.04% of their portfolio CHICAGO, IL 47,25047.2k $1.8m $1.8m 0.04% New
100 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 40,81940.8k $1.5m $1.5m 0.00% Added +2.9k +2,866