INCYTE CORP INCY
COM · Common Stock · CUSIP 45337C102 · ISIN US45337C1027
American pharmaceutical company
- SectorHealth care
- IndustryServices-Commercial Physical & Biological Research
- HeadquartersWilmington, DE
- Founded2001
- Websiteincyte.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($23.6m this quarter). Holder counts are more reliable. Shares outstanding: 223.1m as of 2023-04-25, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $72.50. Options: 15 managers hold calls ($45.5m notional), 13 hold puts ($24.5m).
Trends to Q1 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 537 |
| Q4 2022 | 558 |
| Q1 2023 | 552 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 265 | 251 |
| Q1 2023 | 313 | 230 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $43.1m | $48.3m | 1.12 |
| Q4 2022 | $78.5m | $70.9m | 0.90 |
| Q1 2023 | $45.5m | $24.5m | 0.54 |
Biggest buyers
| ROYAL BANK OF CANADA | Added | +3.2m |
| PICTET ASSET MANAGEMENT SA | Added | +1.4m |
| FMR LLC | Added | +1.3m |
| Invesco Ltd. | Added | +1.3m |
| RENAISSANCE TECHNOLOGIES LLC | Added | +1.0m |
| Man Group plc | New | +820.2k |
| BlackRock Inc. | Added | +798.5k |
| Pacer Advisors, Inc. | Added | +761.8k |
| GOLDMAN SACHS GROUP INC | Added | +694.8k |
| HSBC HOLDINGS PLC | Added | +538.3k |
Biggest sellers
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -7.5m |
| Assenagon Asset Management S.A. | Reduced | -1.0m |
| Balyasny Asset Management L.P. | Sold out | -460.8k |
| APG Asset Management N.V. | Reduced | -371.0k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Reduced | -335.8k |
| Jefferies Financial Group Inc. | Sold out | -278.2k |
| Man Group plc | Sold out | -259.8k |
| UBS Group AG | Reduced | -251.8k |
| PGGM Investments | Sold out | -246.4k |
| ARK Investment Management LLC | Reduced | -222.4k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $13.6m188.7k shares |
| PEAK6 Investments LLC | Added | $6.4m87.9k shares |
| GOLDMAN SACHS GROUP INC | Added | $5.1m70.0k shares |
| SIMPLEX TRADING, LLC | Added | $4.9m67.2k shares |
| BANK OF AMERICA CORP /DE/ | New | $4.2m58.2k shares |
| JANE STREET GROUP, LLC | Reduced | $3.7m51.8k shares |
| CITADEL ADVISORS LLC | Reduced | $2.8m38.8k shares |
| NOMURA HOLDINGS INC | New | $2.6m36.5k shares |
| IMC-Chicago, LLC | Reduced | $787.7k10.9k shares |
| Walleye Trading LLC | Reduced | $411.9k5.7k shares |
Biggest puts
| PEAK6 Investments LLC | Reduced | $5.6m78.0k shares |
| GOLDMAN SACHS GROUP INC | Added | $5.1m70.0k shares |
| BANK OF AMERICA CORP /DE/ | Added | $4.3m59.0k shares |
| JANE STREET GROUP, LLC | Reduced | $2.9m40.4k shares |
| CITADEL ADVISORS LLC | Reduced | $2.1m29.5k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.5m21.0k shares |
| CAPSTONE INVESTMENT ADVISORS, LLC | Reduced | $1.4m18.8k shares |
| IMC-Chicago, LLC | Reduced | $1.0m13.9k shares |
| Walleye Capital LLC | New | $281.9k3.9k shares |
| Walleye Trading LLC | Reduced | $173.4k2.4k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
BAKER BROS. ADVISORS LP
13D · may seek influence
-0.1 pts · filed 2026-05-11
Stated purposeItem 4 of Schedule 13D is supplemented and superseded, as the case may be, as follows: On May 8, 2026 the Adviser acquired beneficial ownership of 15,000 shares of common stock ("Common Stock") of Incyte Corporation (the "Issuer"), as a result of the exercise of 15,000 options to purchase Common Stock at $84.53 per share (the "Exercised Stock Options") held directly by Julian C. Baker. Julian C. Baker currently serves on the Issuer's board of directors (the "Board") as a representative of the Funds. The policy of the Funds and the Adviser does not permit managing members of the Adviser GP or full-time employees of the Adviser to receive compensation for serving as directors of the Issuer, and the Funds are instead entitled to the pecuniary interest in the Exercised Stock Options. Julian C… Full filing |
15.6% |
| BlackRock, Inc. 13G · institution filed 2025-10-17 | 7.8% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 6.3% |
| DODGE & COX 13G · institution filed 2026-05-14 | 6.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q1 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 1 | $115.6m | 2 | $467.7k | — |
| Q1 2022 | 1 | $170.8m | 3 | $2.6m | — |
| Q2 2022 | 0 | — | 1 | $3.7m | — |
| Q3 2022 | 0 | — | 3 | $817.4k | — |
| Q4 2022 | 0 | — | 2 | $1.5m | — |
| Q1 2023 | 0 | — | 4 | $8.2m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-01-31 | Pasquale Maria E EVP & General Counsel | Sold | $67.4k802 shares |
| 2023-01-30 | Pasquale Maria E EVP & General Counsel | Sold | $5.1m60.0k shares |
| 2023-01-26 | Iyengar Vijay K EVP, GMAPPS | Sold | $595.0k7.0k shares |
| 2023-01-26 | Dhanak Dashyant EVP & Chief Scientific Officer | Sold | $205.6k2.4k shares |
| 2023-01-04 | Stein Steven H EVP & Chief Medical Officer | Sold | $2.3m28.4k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2023
| Manager | Shares | Change |
|---|---|---|
| BAKER BROS. ADVISORS LP 14.22% of their portfolio | 36.2m $2.6bn | Added +20.4k |
| VANGUARD GROUP INC 0.04% of their portfolio | 21.8m $1.6bn | Added +224.8k |
| BlackRock Inc. 0.04% of their portfolio | 20.6m $1.5bn | Added +798.5k |
| Dodge & Cox 0.95% of their portfolio | 19.3m $1.4bn | Reduced -30.6k |
| ROYAL BANK OF CANADA 0.27% of their portfolio | 12.7m $915.5m | Added +3.2m |
| STATE STREET CORP 0.04% of their portfolio | 9.3m $673.8m | Reduced -110.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.54% of their portfolio | 5.6m $404.9m | Added +1.0m |
| Invesco Ltd. 0.08% of their portfolio | 4.1m $293.7m | Added +1.3m |
| GEODE CAPITAL MANAGEMENT, LLC 0.04% of their portfolio | 4.0m $285.7m | Added +93.3k |
| FIRST TRUST ADVISORS LP 0.27% of their portfolio | 3.2m $234.2m | Reduced -135.0k |
| Bellevue Group AG 2.98% of their portfolio | 2.8m $205.3m | Reduced -116.5k |
| GOLDMAN SACHS GROUP INC 0.05% of their portfolio | 2.4m $175.3m | Added +694.8k |
| FMR LLC 0.01% of their portfolio | 2.4m $172.2m | Added +1.3m |
| PICTET ASSET MANAGEMENT SA 0.20% of their portfolio | 2.2m $160.2m | Added +1.4m |
| NORTHERN TRUST CORP 0.03% of their portfolio | 2.1m $150.4m | Added +85.5k |
| MORGAN STANLEY 0.01% of their portfolio | 1.9m $137.2m | Added +11.9k |
| ARMISTICE CAPITAL, LLC 3.15% of their portfolio | 1.9m $135.3m | Added +460.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio | 1.8m $131.4m | Reduced -101.9k |
| NORGES BANK 0.03% of their portfolio | 1.8m $131.2m | Added +256.6k |
| Amundi 0.07% of their portfolio | 1.7m $124.3m | Added +395.6k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.74% of their portfolio | 1.7m $120.6m | Added +338.3k |
| Legal & General Group Plc 0.04% of their portfolio | 1.6m $112.1m | Added +38.5k |
| ACADIAN ASSET MANAGEMENT LLC 0.45% of their portfolio | 1.4m $102.9m | Added +387.8k |
| Bank of New York Mellon Corp 0.02% of their portfolio | 1.4m $100.9m | Reduced -38.2k |
| Paradigm Biocapital Advisors LP 8.64% of their portfolio | 1.3m $91.2m | Added +408.9k |
| TWO SIGMA ADVISERS, LP 0.22% of their portfolio | 1.2m $86.4m | Added +316.8k |
| LSV ASSET MANAGEMENT 0.19% of their portfolio | 1.2m $86.2m | Reduced -6.5k |
| California Public Employees Retirement System 0.08% of their portfolio | 1.2m $85.0m | Reduced -58.2k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.04% of their portfolio | 1.2m $84.7m | Reduced -335.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.03% of their portfolio | 1.2m $83.6m | Added +51.7k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.05% of their portfolio | 1.1m $82.2m | Reduced -9.4k |
| Polar Capital Holdings Plc 0.58% of their portfolio | 1.1m $79.5m | Reduced -135.1k |
| CREDIT SUISSE AG/ 0.07% of their portfolio | 1.0m $73.3m | Reduced -14.8k |
| HSBC HOLDINGS PLC 0.09% of their portfolio | 991.8k $71.7m | Added +538.3k |
| APG Asset Management N.V. 0.13% of their portfolio | 924.2k $61.5m | Reduced -371.0k |
| Allspring Global Investments Holdings, LLC 0.11% of their portfolio | 889.0k $64.2m | Added +436.3k |
| DEUTSCHE BANK AG\ 0.04% of their portfolio | 888.4k $64.2m | Added +261.5k |
| D. E. Shaw & Co., Inc. 0.10% of their portfolio | 873.9k $63.2m | Added +73.0k |
| AQR CAPITAL MANAGEMENT LLC 0.13% of their portfolio | 846.4k $60.4m | Added +133.1k |
| Candriam S.C.A. 0.39% of their portfolio | 837.2k $55.7m | Reduced -30.6k |
| Man Group plc 0.21% of their portfolio | 820.2k $59.3m | New |
| Pacer Advisors, Inc. 0.24% of their portfolio | 762.4k $55.1m | Added +761.8k |
| DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio | 752.6k $54.4m | Added +44.8k |
| Sumitomo Mitsui Trust Group, Inc. 0.04% of their portfolio | 750.8k $54.3m | Added +5.4k |
| Swiss National Bank 0.04% of their portfolio | 750.5k $54.2m | Reduced -17.9k |
| ARK Investment Management LLC 0.36% of their portfolio | 728.0k $52.6m | Reduced -222.4k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 695.0k $50.2m | Added +325.0k |
| Russell Investments Group, Ltd. 0.10% of their portfolio | 683.4k $49.2m | Added +12.6k |
| AVIVA PLC 0.22% of their portfolio | 665.2k $48.1m | Added +277.7k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.21% of their portfolio | 647.4k $46.8m | Added +15.2k |
| Allianz Asset Management GmbH 0.10% of their portfolio | 644.7k $46.6m | Reduced -9.3k |
| Qube Research & Technologies Ltd 0.26% of their portfolio | 631.6k $45.6m | Added +277.4k |
| MILLENNIUM MANAGEMENT LLC 0.05% of their portfolio | 624.7k $45.1m | Added +329.3k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 608.9k $44.0m | Added +331.3k |
| BANK OF MONTREAL /CAN/ 0.02% of their portfolio | 601.9k $44.7m | Added +383.8k |
| Woodline Partners LP 0.61% of their portfolio | 592.8k $42.8m | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.13% of their portfolio | 591.3k $42.7m | Added +198.2k |
| Robeco Institutional Asset Management B.V. 0.11% of their portfolio | 577.0k $41.7m | Added +234.9k |
| Swedbank AB 0.08% of their portfolio | 564.1k $40.8m | Unchanged |
| AMERICAN CENTURY COMPANIES INC 0.03% of their portfolio | 555.9k $40.2m | Added +383.8k |
| RHUMBLINE ADVISERS 0.05% of their portfolio | 551.5k $39.9m | Added +9.0k |
| CITIGROUP INC 0.05% of their portfolio | 500.0k $36.1m | Added +181.5k |
| Caisse de depot et placement du Quebec 0.10% of their portfolio | 496.4k $35.9m | Added +60.9k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 495.6k $35.8m | Reduced -6.5k |
| AustralianSuper Pty Ltd 0.23% of their portfolio | 467.6k $33.8m | Added +9.1k |
| JUPITER ASSET MANAGEMENT LTD 0.47% of their portfolio | 467.3k $33.8m | Added +235.8k |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main 0.06% of their portfolio | 466.3k $33.7m | Added +16.5k |
| BARCLAYS PLC 0.03% of their portfolio | 465.3k $33.6m | Added +44.0k |
| ASHFORD CAPITAL MANAGEMENT INC 4.93% of their portfolio | 455.7k $32.9m | Added +3.6k |
| SECTOR GAMMA AS 7.57% of their portfolio | 432.2k $31.2m | Added +20.7k |
| Grantham, Mayo, Van Otterloo & Co. LLC 0.16% of their portfolio | 428.5k $31.0m | Reduced -1.5k |
| COUNTRY TRUST BANK 0.86% of their portfolio | 419.1k $30.3m | Reduced -52.7k |
| Skandinaviska Enskilda Banken AB (publ) 0.21% of their portfolio | 414.6k $30.0m | Added +123.7k |
| Korea Investment CORP 0.08% of their portfolio | 400.3k $28.9m | Added +167.8k |
| Capital World Investors 0.01% of their portfolio | 396.0k $28.6m | Unchanged |
| CANADA PENSION PLAN INVESTMENT BOARD 0.04% of their portfolio | 375.5k $27.1m | Added +121.4k |
| PANAGORA ASSET MANAGEMENT INC 0.16% of their portfolio | 356.9k $25.8m | Reduced -13.9k |
| Hudson Bay Capital Management LP 0.14% of their portfolio | 320.4k $23.2m | Added +200.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.03% of their portfolio | 316.9k $22.9m | Reduced -2.8k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 313.8k $22.7m | Added +20.5k |
| ADAMS DIVERSIFIED EQUITY FUND, INC. 0.99% of their portfolio | 304.3k $22.0m | Unchanged |
| National Pension Service 0.04% of their portfolio | 299.0k $21.2m | Unchanged |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC 5.63% of their portfolio | 279.0k $20.2m | Added +50.0k |
| Bridgewater Associates, LP 0.12% of their portfolio | 276.5k $20.0m | Added +5.1k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 269.1k $19.4m | Reduced -7.5m |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 268.6k $19.4m | Added +1.2k |
| BNP PARIBAS FINANCIAL MARKETS 0.04% of their portfolio | 254.3k $18.4m | Reduced -152.6k |
| INTECH INVESTMENT MANAGEMENT LLC 0.14% of their portfolio | 244.4k $17.7m | Added +75.3k |
| Summit Global Investments 1.36% of their portfolio | 243.0k $17.6m | Added +3.1k |
| MACKENZIE FINANCIAL CORP 0.03% of their portfolio | 242.8k $17.5m | Added +1.4k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 240.7k $17.4m | Reduced -70.5k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.04% of their portfolio | 239.1k $17.3m | Unchanged |
| Squarepoint Ops LLC 0.12% of their portfolio | 231.4k $16.7m | New |
| Mitsubishi UFJ Trust & Banking Corp 0.04% of their portfolio | 230.8k $16.7m | Added +18.6k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.04% of their portfolio | 222.1k $16.1m | Reduced -3.9k |
| UBS Group AG 0.01% of their portfolio | 216.1k $15.6m | Reduced -251.8k |
| Baird Financial Group, Inc. 0.04% of their portfolio | 216.0k $15.6m | Reduced -19.9k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 211.7k $15.3m | Added +4.2k |
| WORLDQUANT MILLENNIUM ADVISORS LLC 0.27% of their portfolio | 203.2k $14.7m | Added +123.5k |
| South Dakota Investment Council 0.31% of their portfolio | 201.9k $14.6m | Added +10.1k |