Vault-13

ENLIVEN THERAPEUTICS INC ELVN

COM · Common Stock · CUSIP 29337E102

64 institutional holders +19 vs Q1 2023
39,126,39439.1m shares reported held*
95.1% of all shares outstanding*
$797.9mreported value*
26 new 18 added 11 reduced 7 sold out net bought ≈ $48.4m (+2.4m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 41.2m as of 2023-08-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $20.39. Options: 3 managers hold calls ($47.6k notional), 1 hold puts ($0).

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

0255075Q1 23: 45Q2 23: 6464Q1 23Q2 23
Numbers
QuarterHolders
Q1 202345
Q2 202364

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$2.5m$5m$7.5m$10mQ3 22 calls: $0Q3 22 puts: $0Q3 22P/C —Q4 22 calls: $0Q4 22 puts: $0Q4 22P/C —Q1 23 calls: $8.2mQ1 23 puts: $5.5kQ1 23P/C 0.00Q2 23 calls: $47.6kQ2 23 puts: $0Q2 23P/C 0.00
Numbers
QuarterCallsPutsP/C
Q3 2022$0$0—
Q4 2022$0$0—
Q1 2023$8.2m$5.5k0.00
Q2 2023$47.6k$00.00

Biggest buyers

BlackRock Inc. Added +1,512,680+1.5m
VANGUARD GROUP INC Added +990,590+990.6k
Commodore Capital LP Added +616,907+616.9k
STATE STREET CORP Added +456,827+456.8k
GEODE CAPITAL MANAGEMENT, LLC Added +379,056+379.1k
Fairmount Funds Management LLC Added +199,687+199.7k
NORTHERN TRUST CORP New +195,940+195.9k
BANK OF MONTREAL /CAN/ New +191,893+191.9k
HighVista Strategies LLC New +121,073+121.1k
ACUTA CAPITAL PARTNERS, LLC Added +73,521+73.5k

Biggest sellers

FMR LLC Reduced -2,325,353-2.3m
JANUS HENDERSON GROUP PLC Reduced -231,160-231.2k
BML Capital Management, LLC Reduced -137,947-137.9k
Logos Global Management LP Reduced -94,153-94.2k
MILLENNIUM MANAGEMENT LLC Sold out -46,874-46.9k
RENAISSANCE TECHNOLOGIES LLC Reduced -34,108-34.1k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Sold out -17,167-17.2k
GOLDMAN SACHS GROUP INC Reduced -14,125-14.1k
MIRABELLA FINANCIAL SERVICES LLP Sold out -11,670-11.7k
Cubist Systematic Strategies, LLC Sold out -8,986-9.0k

Biggest calls

SIMPLEX TRADING, LLC New $44.0k2.2k shares
CITADEL ADVISORS LLC Reduced $3.6k175 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. New $00 shares

Biggest puts

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
FMR LLC 13G · institution +1.7 pts · filed 2026-08-06 15.0% +1.7 pts 10.7m≈ $543.7m 2026-08-06
ORBIMED ADVISORS LLC 13D · may seek influence -1.4 pts · filed 2026-06-24
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer either… Full filing
9.5% -1.4 pts 6.8m≈ $343.8m 2026-06-24
Polar Capital Holdings Plc 13G · institution no change · filed 2026-06-22 8.5% no change 5.1m≈ $256.6m 2026-06-22
Commodore Capital LP 13G · passive investor -2.2 pts · filed 2026-05-15 7.7% -2.2 pts 4.8m≈ $243.6m 2026-05-15
BlackRock, Inc. 13G · institution +2.0 pts · filed 2026-10-27 7.1% +2.0 pts 5.2m≈ $264.2m 2026-10-27
Vestal Point Capital, LP 13G · institution -1.1 pts · filed 2026-05-15 5.4% -1.1 pts 3.2m≈ $164.9m 2026-05-15

Fell to 5% or below in the last year: Venrock Healthcare Capital Partners III, L.P. (2.8%, 2026-05-15), Fairmount Funds Management LLC (3.1%, 2026-05-15)

Insider purchases and sales in Q2 2023

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
202Q3 21: 0 buyingQ3 21: 0 sellingQ4 21: 0 buyingQ4 21: 1 sellingQ4 21Q1 22: 1 buyingQ1 22: 0 sellingQ2 22: 0 buyingQ2 22: 0 sellingQ2 22Q3 22: 0 buyingQ3 22: 0 sellingQ4 22: 0 buyingQ4 22: 0 sellingQ4 22Q1 23: 0 buyingQ1 23: 2 sellingQ2 23: 0 buyingQ2 23: 0 sellingQ2 23
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20210—0——
Q4 20210—1$159.4k—
Q1 20221$313.6k0——
Q2 20220—0——
Q3 20220—0——
Q4 20220—0——
Q1 20230—2$199.2k—
Q2 20230—0——

None reported in Q2 2023.

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 ORBIMED ADVISORS LLC 3.35% of their portfolio New York, NY 8,998,3389.0m $183.7m $183.7m 3.35% Added +2.1k +2,125
2 5AM Venture Management, LLC 29.48% of their portfolio SAN FRANCISCO, CA 5,798,4755.8m $118.3m $118.3m 29.48% Unchanged
3 FMR LLC 0.01% of their portfolio BOSTON, MA 4,001,6114.0m $81.7m $81.7m 0.01% Reduced -2.3m -2,325,353
4 Commodore Capital LP 5.39% of their portfolio NEW YORK, NY 2,348,2722.3m $47.9m $47.9m 5.39% Added +616.9k +616,907
5 CITADEL ADVISORS LLC 0.05% of their portfolio MIAMI, FL 2,296,2102.3m $46.9m $46.9m 0.05% Unchanged
6 Venrock Adviser, LLC 7.28% of their portfolio NEW YORK, NY 2,230,1272.2m $45.5m $45.5m 7.28% Added +16.0k +15,985
7 Fairmount Funds Management LLC 6.11% of their portfolio WEST CONSHOHOCKEN, PA 2,124,6252.1m $43.4m $43.4m 6.11% Added +199.7k +199,687
8 RA CAPITAL MANAGEMENT, L.P. 0.82% of their portfolio BOSTON, MA 2,122,4652.1m $43.3m $43.3m 0.82% Unchanged
9 Cormorant Asset Management, LP 2.25% of their portfolio BOSTON, MA 1,936,1331.9m $39.5m $39.5m 2.25% Unchanged
10 BlackRock Inc. 0.00% of their portfolio New York, NY 1,546,4751.5m $31.6m $31.6m 0.00% Added +1.5m +1,512,680
11 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 1,142,5041.1m $23.3m $23.3m 0.00% Added +990.6k +990,590
12 Frazier Life Sciences Management, L.P. 1.01% of their portfolio PALO ALTO, CA 830,983831.0k $17.0m $17.0m 1.01% Unchanged
13 Boxer Capital, LLC 0.67% of their portfolio San Diego, CA 710,644710.6k $14.5m $14.5m 0.67% Unchanged
14 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 466,251466.3k $9.5m $9.5m 0.00% Added +456.8k +456,827
15 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 414,444414.4k $8.5m $8.5m 0.00% Added +379.1k +379,056
16 JANUS HENDERSON GROUP PLC 0.00% of their portfolio LONDON, X0 370,994371.0k $7.6m $7.6m 0.00% Reduced -231.2k -231,160
17 Logos Global Management LP 0.87% of their portfolio San Francisco, CA 307,076307.1k $6.3m $6.3m 0.87% Reduced -94.2k -94,153
18 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 195,940195.9k $4.0m $4.0m 0.00% New
19 BANK OF MONTREAL /CAN/ 0.00% of their portfolio TORONTO, A6 191,893191.9k $3.9m $3.9m 0.00% New
20 HighVista Strategies LLC 1.13% of their portfolio BOSTON, MA 121,073121.1k $2.5m $2.5m 1.13% New
21 ACUTA CAPITAL PARTNERS, LLC 1.44% of their portfolio REDWOOD CITY, CA 104,500104.5k $2.1m $2.1m 1.44% Added +73.5k +73,521
22 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 80,92480.9k $1.7m $1.7m 0.00% Added +65.6k +65,629
23 BML Capital Management, LLC 1.36% of their portfolio ZIONSVILLE, IN 74,23274.2k $1.5m $1.5m 1.36% Reduced -137.9k -137,947
24 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 64,69564.7k $1.3m $1.3m 0.00% New
25 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 62,46262.5k $1.3m $1.3m 0.00% New
26 JBF Capital, Inc. 0.21% of their portfolio Aspen, CO 50,05050.0k $1.0m $1.0m 0.21% Unchanged
27 Swiss National Bank 0.00% of their portfolio ZURICH, V8 49,17349.2k $1.0m $1.0m 0.00% New
28 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 36,15036.1k $738.0k $738.0k 0.00% Reduced -34.1k -34,108
29 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 34,79634.8k $710.2k $710.2k 0.00% New
30 PRELUDE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio NEW YORK, NY 33,55033.5k $26.8k $26.8k 0.00% Reduced -512 -512
31 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 33,32133.3k $680.1k $680.1k 0.00% Added +15.9k +15,903
32 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 30,65530.7k $625.7k $625.7k 0.00% Added +30.6k +30,561
33 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 27,60627.6k $563.4k $563.4k 0.00% New
34 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 27,28627.3k $556.9k $556.9k 0.00% Reduced -14.1k -14,125
35 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 24,05524.1k $491.0k $491.0k 0.00% New
36 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 23,76223.8k $485.0k $485.0k 0.00% Added +13.8k +13,847
37 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 22,18222.2k $452.7k $452.7k 0.00% New
38 Legal & General Group Plc 0.00% of their portfolio London, X0 18,05518.1k $368.5k $368.5k 0.00% New
39 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio HOUSTON, TX 17,95017.9k $366.4k $366.4k 0.01% Unchanged
40 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 17,04317.0k $347.8k $347.8k 0.00% Added +10.5k +10,498
41 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 14,82714.8k $302.6k $302.6k 0.00% Added +7.6k +7,600
42 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 12,34512.3k $252.0k $252.0k 0.00% New
43 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 11,68511.7k $238.5k $238.5k 0.00% New
44 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 11,27611.3k $230.1k $230.1k 0.00% New
45 AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio New York, NY 11,23511.2k $229.3k $229.3k 0.00% New
46 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 10,82310.8k $220.9k $220.9k 0.00% Reduced -440 -440
47 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 10,53110.5k $214.9k $214.9k 0.00% Reduced -7.9k -7,913
48 DENALI ADVISORS LLC 0.07% of their portfolio SAN DIEGO, CA 9,9009.9k $202.1k $202.1k 0.07% New
49 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 9,3319.3k $190.4k $190.4k 0.00% New
50 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 9,2009.2k $187.8k $187.8k 0.00% New
51 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 8,8708.9k $181.0k $181.0k 0.00% Added +8.8k +8,846
52 EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio Oklahoma City, OK 6,9346.9k $141.5k $141.5k 0.00% New
53 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 3,0753.1k $63.0k $63.0k 0.00% Added +2.6k +2,589
54 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 2,2702.3k $46.0k $46.0k 0.00% New
55 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 1,9281.9k $39.4k $39.4k 0.00% New
56 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 1,3821.4k $28.2k $28.2k 0.00% Reduced -275 -275
57 Dorsey Wright & Associates 0.01% of their portfolio PASADENA, CA 1,3751.4k $28.1k $28.1k 0.01% Added +138 +138
58 Metropolitan Life Insurance Co/NY 0.00% of their portfolio New York, NY 1,2791.3k $26.1k $26.1k 0.00% New
59 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 1,0001.0k $20.4k $20.4k 0.00% New
60 UBS Group AG 0.00% of their portfolio ZURICH, V8 8181 $1.7k $1.7k 0.00% Reduced -253 -253
61 Mariner Managed Account Solutions, LLC 0.00% of their portfolio Boston, MA 5050 $1.0k $1.0k 0.00% Unchanged
62 NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio ST. LOUIS, MO 1616 $327 $327 0.00% New
63 Covestor Ltd 0.00% of their portfolio LONDON, X0 11 $0 $0 0.00% New
64 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% New