ANAPTYSBIO INC ANAB
COM · Common Stock · CUSIP 032724106
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($515.0k this quarter). Holder counts are more reliable. Shares outstanding: 27.4m as of 2024-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $25.06. Options: 4 managers hold calls ($794.4k notional), 3 hold puts ($706.7k).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 114 |
| Q4 2022 | 119 |
| Q1 2023 | 114 |
| Q2 2023 | 117 |
| Q3 2023 | 117 |
| Q4 2023 | 120 |
| Q1 2024 | 134 |
| Q2 2024 | 136 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 46 | 47 |
| Q1 2023 | 50 | 56 |
| Q2 2023 | 52 | 47 |
| Q3 2023 | 48 | 52 |
| Q4 2023 | 45 | 56 |
| Q1 2024 | 65 | 52 |
| Q2 2024 | 66 | 68 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $1.0m | $1.1m | 1.06 |
| Q4 2023 | $1.3m | $1.2m | 0.93 |
| Q1 2024 | $1.5m | $1.4m | 0.96 |
| Q2 2024 | $794.4k | $706.7k | 0.89 |
Biggest buyers
| FMR LLC | Added | +2.7m |
| Frazier Life Sciences Management, L.P. | Added | +1.3m |
| Camber Capital Management LP | New | +500.0k |
| Parkman Healthcare Partners LLC | New | +256.3k |
| Schonfeld Strategic Advisors LLC | New | +171.6k |
| ADAR1 Capital Management, LLC | Added | +154.8k |
| EVENTIDE ASSET MANAGEMENT, LLC | Added | +141.3k |
| ExodusPoint Capital Management, LP | New | +140.5k |
| NORDEA INVESTMENT MANAGEMENT AB | New | +135.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +128.5k |
Biggest sellers
| MORGAN STANLEY | Reduced | -1.8m |
| GREAT POINT PARTNERS LLC | Reduced | -952.0k |
| Point72 Asset Management, L.P. | Reduced | -846.2k |
| Deep Track Capital, LP | Sold out | -529.5k |
| Saturn V Capital Management LP | Reduced | -336.4k |
| Blackstone Inc. | Sold out | -328.7k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -273.4k |
| STEMPOINT CAPITAL LP | Sold out | -269.5k |
| Woodline Partners LP | Reduced | -256.5k |
| CITADEL ADVISORS LLC | Reduced | -243.8k |
Biggest calls
| CITIGROUP INC | Reduced | $601.4k24.0k shares |
| CITADEL ADVISORS LLC | Added | $155.4k6.2k shares |
| ADAR1 Capital Management, LLC | Reduced | $37.6k1.5k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITIGROUP INC | Reduced | $601.4k24.0k shares |
| CITADEL ADVISORS LLC | Added | $105.3k4.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution -2.2 pts · filed 2025-04-17 | 6.2% |
| Sirenia Capital Management LP 13G · institution -1.7 pts · filed 2026-08-14 | 5.0% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.2%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26), MORGAN STANLEY (3.6%, 2026-02-11), MILLENNIUM MANAGEMENT LLC (2.9%, 2026-01-16)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 1 | $13.1k | — |
| Q4 2022 | 0 | — | 0 | — | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 3 | $116.3k | — |
| Q4 2023 | 0 | — | 1 | $12.5k | — |
| Q1 2024 | 0 | — | 4 | $3.9m | $125.0k |
| Q2 2024 | 0 | — | 3 | $125.9k | $80.8k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-06-21 | FENTON DENNIS M Director | Sold plan | $45.2k1.9k shares |
| 2024-06-18 | RENTON HOLLINGS Director | Sold | $45.2k1.9k shares |
| 2024-05-22 | MULROY DENNIS CHIEF FINANCIAL OFFICER | Sold plan | $35.6k1.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| EcoR1 Capital, LLC 5.77% of their portfolio | 7.5m $188.5m | Unchanged |
| FMR LLC 0.00% of their portfolio | 2.9m $71.9m | Added +2.7m |
| Frazier Life Sciences Management, L.P. 2.54% of their portfolio | 2.2m $54.3m | Added +1.3m |
| BlackRock Inc. 0.00% of their portfolio | 1.8m $44.4m | Added +49.9k |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.4m $35.7m | Added +70.4k |
| TANG CAPITAL MANAGEMENT LLC 3.40% of their portfolio | 1.3m $33.4m | Unchanged |
| Boxer Capital, LLC 1.72% of their portfolio | 1.3m $32.6m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 966.9k $24.2m | Reduced -240.6k |
| Palo Alto Investors LP 2.33% of their portfolio | 803.6k $20.1m | Added +3.7k |
| First Light Asset Management, LLC 1.71% of their portfolio | 779.2k $19.5m | Reduced -165.0k |
| MANGROVE PARTNERS IM, LLC 1.38% of their portfolio | 689.5k $17.3m | Unchanged |
| EVENTIDE ASSET MANAGEMENT, LLC 0.24% of their portfolio | 568.3k $14.2m | Added +141.3k |
| Camber Capital Management LP 0.48% of their portfolio | 500.0k $12.5m | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 465.4k $11.7m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 452.1k $11.3m | Added +30.4k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 373.8k $9.4m | Reduced -273.4k |
| 5AM Venture Management, LLC 2.01% of their portfolio | 357.7k $9.0m | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 335.9k $8.4m | Reduced -133.9k |
| Assenagon Asset Management S.A. 0.02% of their portfolio | 306.6k $7.7m | Added +84.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 300.2k $7.5m | Added +128.5k |
| Parkman Healthcare Partners LLC 0.87% of their portfolio | 256.3k $6.4m | New |
| Woodline Partners LP 0.06% of their portfolio | 252.4k $6.3m | Reduced -256.5k |
| Saturn V Capital Management LP 2.36% of their portfolio | 249.6k $6.3m | Reduced -336.4k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 194.5k $4.9m | Added +44.1k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 194.1k $4.9m | Reduced -7.0k |
| Schonfeld Strategic Advisors LLC 0.03% of their portfolio | 171.6k $4.3m | New |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 171.4k $4.3m | Reduced -15.4k |
| ADAR1 Capital Management, LLC 0.79% of their portfolio | 155.8k $3.9m | Added +154.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 155.3k $3.9m | Added +9.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 152.7k $3.8m | Added +52.5k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 140.5k $3.5m | Added +20.5k |
| ExodusPoint Capital Management, LP 0.04% of their portfolio | 140.5k $3.5m | New |
| NORDEA INVESTMENT MANAGEMENT AB 0.00% of their portfolio | 135.6k $3.4m | New |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 122.4k $3.1m | Reduced -9.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 104.0k $2.6m | Added +49.5k |
| MACQUARIE GROUP LTD 0.00% of their portfolio | 93.7k $2.3m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 91.8k $2.3m | Reduced -1.8m |
| PLATINUM INVESTMENT MANAGEMENT LTD 0.08% of their portfolio | 82.4k $2.1m | Added +16.2k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 81.0k $2.0m | Reduced -243.8k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.06% of their portfolio | 79.8k $2.0m | Reduced -3.2k |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 75.8k $1.9m | Added +32.3k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 74.5k $1.9m | Added +10.4k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.04% of their portfolio | 72.1k $1.8m | Added +17.9k |
| Fisher Asset Management, LLC 0.00% of their portfolio | 65.0k $1.6m | Reduced -5.7k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 62.9k $1.6m | Added +3.8k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 56.0k $1.4m | Reduced -8.2k |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 55.0k $1.4m | Reduced -77.5k |
| Cubist Systematic Strategies, LLC 0.02% of their portfolio | 54.3k $1.4m | New |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 49.7k $1.2m | Reduced -41.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 47.2k $1.2m | Reduced -2.2k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 43.4k $1.1m | Added +4.7k |
| TD Asset Management Inc 0.00% of their portfolio | 37.8k $947.3k | Added +15.2k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 36.1k $903.6k | Added +16 |
| Jump Financial, LLC 0.02% of their portfolio | 35.7k $894.6k | New |
| FMB WEALTH MANAGEMENT 0.68% of their portfolio | 35.6k $891.9k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 34.6k $866.5k | Reduced -29.6k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 30.5k $764.8k | Added +2.0k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 30.5k $764.3k | Reduced -6.2k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 29.7k $744.6k | Added +525 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 29.7k $743.3k | Added +12.7k |
| MARTINGALE ASSET MANAGEMENT L P 0.02% of their portfolio | 28.6k $717.6k | Unchanged |
| Trexquant Investment LP 0.01% of their portfolio | 26.7k $669.5k | Reduced -5.8k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 26.6k $665.7k | Added +20.7k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 25.3k $634.3k | Added +8.4k |
| GREAT POINT PARTNERS LLC 0.12% of their portfolio | 25.0k $626.5k | Reduced -952.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 23.2k $580.4k | Reduced -3.6k |
| ALPS ADVISORS INC 0.00% of their portfolio | 21.3k $534.5k | Added +2.6k |
| Swiss National Bank 0.00% of their portfolio | 21.0k $526.3k | Unchanged |
| Y-Intercept (Hong Kong) Ltd 0.03% of their portfolio | 20.5k $512.6k | New |
| BARCLAYS PLC 0.00% of their portfolio | 20.4k $510.6k | Reduced -8.9k |
| Invesco Ltd. 0.00% of their portfolio | 18.9k $473.9k | Reduced -1.2k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 17.9k $448.6k | Reduced -846.2k |
| Alpha DNA Investment Management LLC 0.23% of their portfolio | 15.9k $399.0k | New |
| Legal & General Group Plc 0.00% of their portfolio | 15.3k $384.6k | Added +1.5k |
| PDT Partners, LLC 0.03% of their portfolio | 13.8k $347.1k | Reduced -2.4k |
| XTX Topco Ltd 0.03% of their portfolio | 13.6k $340.9k | Reduced -2.1k |
| Tower Research Capital LLC (TRC) 0.01% of their portfolio | 13.3k $334.1k | Added +12.1k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 12.3k $307.1k | Added +1.2k |
| Engineers Gate Manager LP 0.01% of their portfolio | 12.1k $302.8k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 11.6k $291.0k | First filing |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 11.2k $280.5k | Reduced -254 |
| Squarepoint Ops LLC 0.00% of their portfolio | 11.2k $280.3k | Reduced -482 |
| Cresset Asset Management, LLC 0.00% of their portfolio | 11.0k $276.8k | New |
| CITIGROUP INC 0.00% of their portfolio | 10.6k $264.7k | Reduced -68.5k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 10.5k $263.8k | First filing |
| Corton Capital Inc. 0.14% of their portfolio | 10.5k $263.7k | New |
| ALGERT GLOBAL LLC 0.01% of their portfolio | 10.2k $255.1k | Added +1.1k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 9.3k $233.8k | New |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 9.2k $230.8k | Reduced -4.9k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 8.6k $214.9k | Reduced -914 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 8.2k $206.0k | Reduced -739 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 7.9k $198.6k | Added +10 |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 5.8k $145.1k | Reduced -2.4k |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 0.00% of their portfolio | 4.9k $122.0k | Reduced -1.0k |
| VIRTUS ADVISERS, LLC 0.05% of their portfolio | 3.7k $93.5k | Reduced -818 |
| Headlands Technologies LLC 0.01% of their portfolio | 3.6k $89.0k | Added +2.9k |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 3.2k $80.4k | Reduced -1.9k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 2.9k $72.0k | Reduced -21 |
| EntryPoint Capital, LLC 0.03% of their portfolio | 2.4k $59.9k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 2.1k $51.0k | Added +1.1k |