ALX ONCOLOGY HLDGS INC ALXO
COM · Common Stock · CUSIP 00166B105
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.2m this quarter). Holder counts are more reliable. Shares outstanding: 52.7m as of 2024-08-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $6.03. Options: 9 managers hold calls ($3.4m notional), 6 hold puts ($1.9m).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 99 |
| Q4 2022 | 88 |
| Q1 2023 | 87 |
| Q2 2023 | 76 |
| Q3 2023 | 77 |
| Q4 2023 | 94 |
| Q1 2024 | 107 |
| Q2 2024 | 114 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 24 | 50 |
| Q1 2023 | 42 | 37 |
| Q2 2023 | 36 | 41 |
| Q3 2023 | 35 | 32 |
| Q4 2023 | 62 | 30 |
| Q1 2024 | 51 | 40 |
| Q2 2024 | 66 | 50 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $1.0m | $61.4k | 0.06 |
| Q4 2023 | $4.1m | $1.3m | 0.31 |
| Q1 2024 | $1.6m | $399.9k | 0.25 |
| Q2 2024 | $3.4m | $1.9m | 0.55 |
Biggest buyers
| Paradigm Biocapital Advisors LP | New | +1.6m |
| MILLENNIUM MANAGEMENT LLC | Added | +1.3m |
| Vestal Point Capital, LP | Added | +990.0k |
| MPM BIOIMPACT LLC | Added | +912.4k |
| MARSHALL WACE, LLP | Added | +514.1k |
| BlackRock Inc. | Added | +466.1k |
| Privium Fund Management B.V. | New | +397.0k |
| KENNEDY CAPITAL MANAGEMENT LLC | New | +307.5k |
| Point72 Asset Management, L.P. | New | +304.1k |
| FMR LLC | Added | +292.2k |
Biggest sellers
| Cormorant Asset Management, LP | Sold out | -3.1m |
| CITADEL ADVISORS LLC | Reduced | -1.2m |
| ORBIMED ADVISORS LLC | Reduced | -823.5k |
| MORGAN STANLEY | Reduced | -356.1k |
| Redmile Group, LLC | Reduced | -290.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -222.1k |
| FEDERATED HERMES, INC. | Reduced | -199.0k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Sold out | -160.0k |
| Squarepoint Ops LLC | Sold out | -106.4k |
| LOS ANGELES CAPITAL MANAGEMENT LLC | Sold out | -99.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $979.3k162.4k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $783.9k130.0k shares |
| Affinity Asset Advisors, LLC | New | $603.0k100.0k shares |
| Caption Management, LLC | New | $452.2k75.0k shares |
| CITADEL ADVISORS LLC | Added | $209.8k34.8k shares |
| TORNO CAPITAL, LLC | New | $193.0k32.0k shares |
| SIMPLEX TRADING, LLC | Added | $157.0k26.2k shares |
| GROUP ONE TRADING LLC | Added | $51.3k8.5k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SILVERARC CAPITAL MANAGEMENT, LLC | New | $1.0m167.9k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $633.1k105.0k shares |
| CITADEL ADVISORS LLC | Added | $220.7k36.6k shares |
| SIMPLEX TRADING, LLC | Reduced | $28.0k4.8k shares |
| GROUP ONE TRADING LLC | Reduced | $8.4k1.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
venBio Global Strategic Fund, L.P.
13D · may seek influence
no change · filed 2026-10-16
Stated purposeItem 4 of the Schedule 13D is hereby amended and supplemented as follows: The responses to Items 3 and 6 of this Amendment No. 2 are incorporated by reference herein. Mr. Goodman resigned from the Issuer's board of directors effective June 29, 2026. Full filing |
10.0% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor new · filed 2026-02-09 | 9.9% |
| HBM Healthcare Investments (Cayman) Ltd. 13G · passive investor -1.9 pts · filed 2026-05-15 | 6.5% |
| TANG CAPITAL PARTNERS LP 13G · passive investor filed 2025-02-14 | 6.3% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-27 | 5.4% |
Fell to 5% or below in the last year: TCG Crossover GP II, LLC (4.2%, 2026-08-14), LSV Associates, LLC (2.2%, 2026-05-27), Redmile Group, LLC (6.8%, 2026-05-15), MILLENNIUM MANAGEMENT LLC (1.5%, 2026-04-28), TANG CAPITAL MANAGEMENT LLC (0.0%, 2025-11-14)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 4 | $68.9k | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 4 | $45.3k | — |
| Q3 2023 | 0 | — | 1 | $47.9k | — |
| Q4 2023 | 0 | — | 4 | $208.0k | — |
| Q1 2024 | 1 | $49.8k | 1 | $37.0k | — |
| Q2 2024 | 1 | $102.4k | 2 | $1.6m | $1.6m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-06-13 | GARCIA PETER S CHIEF FINANCIAL OFFICER | Bought | $102.4k12.0k shares |
| 2024-06-04 | Pons Jaume PRESIDENT & CSO, director | Sold plan | $168.6k20.0k shares |
| 2024-05-13 | Randolph Sophia CHIEF MEDICAL OFFICER, director | Sold plan | $191.4k12.0k shares |
| 2024-05-06 | Pons Jaume PRESIDENT & CSO, director | Sold plan | $318.4k20.0k shares |
| 2024-04-16 | Pons Jaume PRESIDENT & CSO, director | Sold plan | $710.0k50.0k shares |
| 2024-04-04 | Pons Jaume PRESIDENT & CSO, director | Sold plan | $223.0k20.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| venBio Partners LLC 25.26% of their portfolio | 9.7m $58.5m | Unchanged |
| FMR LLC 0.00% of their portfolio | 7.8m $47.1m | Added +292.2k |
| Vivo Capital, LLC 2.35% of their portfolio | 4.2m $25.4m | Unchanged |
| Redmile Group, LLC 1.47% of their portfolio | 4.0m $24.3m | Reduced -290.1k |
| Vestal Point Capital, LP 1.62% of their portfolio | 3.6m $21.7m | Added +990.0k |
| BlackRock Inc. 0.00% of their portfolio | 2.7m $16.2m | Added +466.1k |
| MPM BIOIMPACT LLC 2.04% of their portfolio | 2.2m $13.2m | Added +912.4k |
| ORBIMED ADVISORS LLC 0.23% of their portfolio | 1.9m $11.4m | Reduced -823.5k |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.7m $10.4m | Added +160.8k |
| Paradigm Biocapital Advisors LP 0.36% of their portfolio | 1.6m $9.5m | New |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 1.3m $8.0m | Added +1.3m |
| STATE STREET CORP 0.00% of their portfolio | 705.5k $4.3m | Added +151.7k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 700.4k $4.2m | Added +95.7k |
| MORGAN STANLEY 0.00% of their portfolio | 673.4k $4.1m | Reduced -356.1k |
| MARSHALL WACE, LLP 0.01% of their portfolio | 635.7k $3.8m | Added +514.1k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 438.2k $2.6m | Added +204.1k |
| Privium Fund Management B.V. 0.58% of their portfolio | 397.0k $2.3m | New |
| KENNEDY CAPITAL MANAGEMENT LLC 0.04% of their portfolio | 307.5k $1.9m | New |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 304.1k $1.8m | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 292.2k $1.8m | Added +226.8k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 244.6k $1.5m | Reduced -661 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 236.0k $1.4m | Added +26.3k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.01% of their portfolio | 232.0k $1.4m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 215.3k $1.3m | Added +58.2k |
| Cubist Systematic Strategies, LLC 0.02% of their portfolio | 199.4k $1.2m | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 145.7k $878.7k | Added +18.7k |
| Jump Financial, LLC 0.02% of their portfolio | 140.0k $844.2k | Added +115.2k |
| Walleye Capital LLC 0.01% of their portfolio | 109.8k $661.9k | Added +71.5k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 105.9k $638.5k | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 105.0k $632.9k | Added +25.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 80.8k $487.5k | Reduced -2.9k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 78.1k $470.9k | Added +18.9k |
| EntryPoint Capital, LLC 0.21% of their portfolio | 76.4k $460.8k | Added +73.6k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 75.1k $453.0k | Added +20.8k |
| Susquehanna Portfolio Strategies, LLC 0.02% of their portfolio | 73.5k $443.0k | Reduced -17.5k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 71.7k $432.5k | Added +32.9k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 68.5k $413.1k | Reduced -1.2m |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 67.6k $407.6k | Added +57.6k |
| Aberdeen Group plc 0.00% of their portfolio | 66.2k $399.3k | Unchanged |
| Inspire Investing, LLC 0.04% of their portfolio | 58.7k $354.0k | Added +25.6k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 55.2k $333.0k | Added +5.4k |
| Swiss National Bank 0.00% of their portfolio | 49.4k $297.9k | Added +5.2k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 44.1k $266.2k | New |
| Nan Fung Group Holdings Ltd 0.27% of their portfolio | 42.0k $253.0k | Unchanged |
| ALGERT GLOBAL LLC 0.01% of their portfolio | 41.2k $248.5k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 41.0k $247.3k | Reduced -6.1k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 41.0k $468.0k | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 34.5k $207.9k | Reduced -15.8k |
| Verition Fund Management LLC 0.00% of their portfolio | 32.6k $196.4k | New |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 31.4k $189.5k | New |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 27.0k $162.9k | Reduced -2.1k |
| Legal & General Group Plc 0.00% of their portfolio | 25.9k $156.1k | Added +8.7k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 25.3k $152.3k | Added +2.5k |
| LMR Partners LLP 0.00% of their portfolio | 25.0k $150.8k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 24.6k $148.1k | Added +859 |
| Graham Capital Management, L.P. 0.00% of their portfolio | 23.9k $144.4k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 23.7k $142.8k | Reduced -6.0k |
| SHERBROOKE PARK ADVISERS LLC 0.02% of their portfolio | 22.2k $133.7k | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 21.8k $131.6k | New |
| AlphaQuest LLC 0.02% of their portfolio | 20.8k $125.3k | Reduced -4.3k |
| SG Americas Securities, LLC 0.00% of their portfolio | 20.5k $124.0k | Reduced -3.4k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 18.9k $114.2k | New |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 18.1k $109.0k | Added +6.1k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 17.8k $107.2k | First filing |
| BARCLAYS PLC 0.00% of their portfolio | 17.3k $104.4k | Reduced -11.3k |
| OCCUDO QUANTITATIVE STRATEGIES LP 0.02% of their portfolio | 16.4k $98.9k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 16.1k $97.3k | Added +1.6k |
| UBS Group AG 0.00% of their portfolio | 15.5k $93.2k | Reduced -13.6k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 13.7k $82.4k | Reduced -46.5k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 13.0k $78.5k | First filing |
| Engineers Gate Manager LP 0.00% of their portfolio | 12.6k $76.0k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 12.5k $75.5k | Reduced -124 |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 11.2k $67.6k | New |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 10.8k $62.6k | New |
| VIRTUS ADVISERS, LLC 0.03% of their portfolio | 10.7k $64.7k | Added +4.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 10.6k $65.0k | Reduced -222.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 10.6k $63.8k | Added +1.3k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 10.4k $62.9k | Reduced -1.1k |
| CORNERCAP INVESTMENT COUNSEL INC 0.01% of their portfolio | 10.3k $62.1k | Reduced -148 |
| Invesco Ltd. 0.00% of their portfolio | 10.3k $62.0k | New |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 10.1k $60.9k | Reduced -10.1k |
| DANSKE BANK A/S 0.00% of their portfolio | 8.5k $51.3k | New |
| CITIGROUP INC 0.00% of their portfolio | 8.3k $50.0k | Reduced -35.2k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 7.6k $45.7k | Added +2.8k |
| Caption Management, LLC 0.00% of their portfolio | 6.6k $39.8k | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 6.5k $39.3k | Added +5.2k |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 6.1k $36.9k | Reduced -3.5k |
| STRS OHIO 0.00% of their portfolio | 4.1k $24.7k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 3.1k $19.0k | Added +2.5k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 2.8k $16.8k | Unchanged |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 2.4k $14.0k | Unchanged |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 2.3k $14.1k | New |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 2.3k $14.0k | Reduced -199.0k |
| Point72 (DIFC) Ltd 0.00% of their portfolio | 2.0k $11.8k | New |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 1.6k $9.1k | Reduced -9.4k |
| Bradley & Co. Private Wealth Management, LLC 0.00% of their portfolio | 1.0k $6.0k | Unchanged |
| AMALGAMATED BANK 0.00% of their portfolio | 897 $5.0k | Unchanged |
| Smartleaf Asset Management LLC 0.00% of their portfolio | 631 $3.7k | New |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 606 $3.7k | Added +204 |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 571 $3.4k | New |