Vault-13

WAVE LIFE SCIENCES LTD 96663EUR

SHS · Common Stock · CUSIP Y95308105

145 institutional holders +12 vs Q1 2024
95,571,77395.6m shares reported held*
$476.9mreported value*
34 new 48 added 45 reduced 23 sold out net bought ≈ $2.4m (+484.8k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($45.1k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $4.99. Options: 4 managers hold calls ($164.7k notional), 4 hold puts ($325.4k).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 61Q4 22: 76Q1 23: 74Q2 23: 82Q3 23: 86Q4 23: 116Q1 24: 133Q2 24: 145145Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 202261
Q4 202276
Q1 202374
Q2 202382
Q3 202386
Q4 2023116
Q1 2024133
Q2 2024145

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 38 bought or addedQ4 22: 27 cut or sold outQ4 22Q1 23: 44 bought or addedQ1 23: 31 cut or sold outQ2 23: 46 bought or addedQ2 23: 37 cut or sold outQ2 23Q3 23: 39 bought or addedQ3 23: 35 cut or sold outQ4 23: 84 bought or addedQ4 23: 21 cut or sold outQ4 23Q1 24: 86 bought or addedQ1 24: 47 cut or sold outQ2 24: 82 bought or addedQ2 24: 68 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 20223827
Q1 20234431
Q2 20234637
Q3 20233935
Q4 20238421
Q1 20248647
Q2 20248268

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$500k$1m$1.5m$2mQ3 23 calls: $244.2kQ3 23 puts: $31.9kQ3 23P/C 0.13Q4 23 calls: $1.5mQ4 23 puts: $163.9kQ4 23P/C 0.11Q1 24 calls: $548.9kQ1 24 puts: $144.6kQ1 24P/C 0.26Q2 24 calls: $164.7kQ2 24 puts: $325.4kQ2 24P/C 1.98
Numbers
QuarterCallsPutsP/C
Q3 2023$244.2k$31.9k0.13
Q4 2023$1.5m$163.9k0.11
Q1 2024$548.9k$144.6k0.26
Q2 2024$164.7k$325.4k1.98

Biggest buyers

EMERALD ADVISERS, LLC New +2,493,230+2.5m
EMERALD MUTUAL FUND ADVISERS TRUST New +1,820,938+1.8m
STATE STREET CORP Added +749,007+749.0k
VANGUARD GROUP INC Added +583,600+583.6k
Artal Group S.A. Added +514,851+514.9k
Exome Asset Management LLC New +488,135+488.1k
BlackRock Inc. Added +363,485+363.5k
Avidity Partners Management LP New +350,000+350.0k
Driehaus Capital Management LLC Added +348,300+348.3k
Ghost Tree Capital, LLC New +200,000+200.0k

Biggest sellers

MORGAN STANLEY Reduced -1,998,346-2.0m
Point72 Asset Management, L.P. Reduced -1,859,259-1.9m
Woodline Partners LP Sold out -948,444-948.4k
M28 Capital Management LP Reduced -835,452-835.5k
FMR LLC Reduced -607,693-607.7k
PRICE T ROWE ASSOCIATES INC /MD/ Reduced -421,983-422.0k
Laurion Capital Management LP Reduced -355,027-355.0k
TWO SIGMA INVESTMENTS, LP Reduced -292,046-292.0k
MARSHALL WACE, LLP Reduced -251,303-251.3k
PRIMECAP MANAGEMENT CO/CA/ Reduced -212,224-212.2k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $93.8k18.8k shares
CITADEL ADVISORS LLC Reduced $70.9k14.2k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares
SIMPLEX TRADING, LLC Reduced $0200 shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $207.1k41.5k shares
CITADEL ADVISORS LLC Added $78.3k15.7k shares
SIMPLEX TRADING, LLC Added $40.0k8.1k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
RA CAPITAL MANAGEMENT, L.P. 13D · may seek influence -0.4 pts · filed 2026-04-17
Stated purposeItem 4 of the Statement is hereby amended and supplemented as follows: On April 15, 2026, the Issuer into an Implementation Agreement, dated as of April 15, 2026 (the "Implementation Agreement"), with a newly established Delaware corporation, Wave Life Sciences, Inc. ("Wave-Delaware"). The Implementation Agreement provides for a statutory procedure known as a Scheme of Arrangement (the "Scheme of Arrangement") to be implemented by the Issuer and Wave-Delaware under Singapore law, subject to approval of the High Court of the Republic of Singapore (the "Singapore Court"). Pursuant to the Scheme of Arrangement, all issued ordinary shares in the capital of the Issuer as of immediately prior to the effective time of the Scheme of Arrangement will be exchanged on a one-for-one basis for newly i… Full filing
 17.1% -0.4 pts 34.2m≈ $198.9m 2026-04-17
MAVERICK CAPITAL LTD 13G · passive investor filed 2025-02-14 5.4% 8.3m≈ $48.0m 2025-02-14

Fell to 5% or below in the last year: BlackRock, Inc. (0.0%, 2026-10-27), Adage Capital Management, L.P. (0.5%, 2026-05-13), FMR LLC (2.8%, 2026-05-06)

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 RA CAPITAL MANAGEMENT, L.P. 1.20% of their portfolio BOSTON, MA 18,202,00918.2m $90.8m $90.8m 1.20% Unchanged
2 MAVERICK CAPITAL LTD 0.73% of their portfolio DALLAS, TX 7,669,3617.7m $38.3m $38.3m 0.73% Reduced -18.7k -18,718
3 BlackRock Inc. 0.00% of their portfolio New York, NY 6,738,7356.7m $33.6m $33.6m 0.00% Added +363.5k +363,485
4 M28 Capital Management LP 39.88% of their portfolio STAMFORD, CT 6,164,5486.2m $30.8m $30.8m 39.88% Reduced -835.5k -835,452
5 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.05% of their portfolio Boston, MA 5,357,7195.4m $26.7m $26.7m 0.05% Added +156.3k +156,330
6 683 Capital Management, LLC 2.79% of their portfolio NEW YORK, NY 5,325,0005.3m $26.6m $26.6m 2.79% Reduced -25.0k -25,000
7 Artal Group S.A. 0.59% of their portfolio LUXEMBOURG, N4 4,566,2514.6m $22.8m $22.8m 0.59% Added +514.9k +514,851
8 Bellevue Group AG 0.33% of their portfolio ZURICH, V8 4,094,4584.1m $20.4m $20.4m 0.33% Unchanged
9 Kynam Capital Management, LP 2.08% of their portfolio PRINCETON, NJ 3,975,5214.0m $19.8m $19.8m 2.08% Added +43.4k +43,439
10 PRIMECAP MANAGEMENT CO/CA/ 0.01% of their portfolio PASADENA, CA 2,664,2162.7m $13.3m $13.3m 0.01% Reduced -212.2k -212,224
11 EMERALD ADVISERS, LLC 0.52% of their portfolio LEOLA, PA 2,493,2302.5m $12.4m $12.4m 0.52% New
12 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 2,417,6902.4m $12.1m $12.1m 0.00% Added +583.6k +583,600
13 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 2,263,4262.3m $11.3m $11.3m 0.00% Added +749.0k +749,007
14 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,986,2452.0m $9.9m $9.9m 0.00% Added +73.5k +73,503
15 EMERALD MUTUAL FUND ADVISERS TRUST 0.48% of their portfolio LEOLA, PA 1,820,9381.8m $9.1m $9.1m 0.48% New
16 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 1,664,3001.7m $8.3m $8.3m 0.01% Added +28.7k +28,690
17 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 1,439,2711.4m $7.2m $7.2m 0.00% Reduced -422.0k -421,983
18 TAKEDA PHARMACEUTICAL CO LTD 2.89% of their portfolio Tokyo, M0 1,346,8921.3m $6.7m $6.7m 2.89% Unchanged
19 Driehaus Capital Management LLC 0.04% of their portfolio Chicago, IL 908,096908.1k $4.5m $4.5m 0.04% Added +348.3k +348,300
20 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 837,014837.0k $4.2m $4.2m 0.00% Reduced -2.0m -1,998,346
21 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 784,098784.1k $3.9m $3.9m 0.00% Reduced -127.5k -127,524
22 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 751,725751.7k $3.8m $3.8m 0.00% Reduced -5.6k -5,566
23 Ikarian Capital, LLC 0.90% of their portfolio DALLAS, TX 575,088575.1k $2.9m $2.9m 0.90% Reduced -15.0k -15,000
24 FMR LLC 0.00% of their portfolio BOSTON, MA 561,080561.1k $2.8m $2.8m 0.00% Reduced -607.7k -607,693
25 PLATINUM INVESTMENT MANAGEMENT LTD 0.11% of their portfolio SYDNEY AUSTRALIA 2000, C3 537,345537.3k $2.7m $2.7m 0.11% Reduced -62.8k -62,810
26 Laurion Capital Management LP 0.08% of their portfolio NEW YORK, NY 516,473516.5k $2.6m $2.6m 0.08% Reduced -355.0k -355,027
27 SILVERARC CAPITAL MANAGEMENT, LLC 0.61% of their portfolio BOSTON, MA 495,471495.5k $2.5m $2.5m 0.61% Unchanged
28 Exome Asset Management LLC 2.17% of their portfolio NEW YORK, NY 488,135488.1k $2.4m $2.4m 2.17% New
29 Newtyn Management, LLC 0.44% of their portfolio NEW YORK, NY 475,000475.0k $2.4m $2.4m 0.44% Reduced -25.0k -25,000
30 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 428,311428.3k $2.1m $2.1m 0.00% Added +29.2k +29,212
31 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 403,984404.0k $2.0m $2.0m 0.00% Added +67.4k +67,395
32 Affinity Asset Advisors, LLC 0.29% of their portfolio NEW YORK, NY 375,000375.0k $1.9m $1.9m 0.29% Added +88.4k +88,415
33 JACOBS LEVY EQUITY MANAGEMENT, INC 0.01% of their portfolio FLORHAM PARK, NJ 366,601366.6k $1.8m $1.8m 0.01% Added +124.7k +124,741
34 Avidity Partners Management LP 0.07% of their portfolio DALLAS, TX 350,000350.0k $1.7m $1.7m 0.07% New
35 Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio VANCOUVER, A1 339,749339.7k $1.7m $1.7m 0.01% Reduced -122.8k -122,833
36 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 326,890326.9k $1.6m $1.6m 0.00% Added +103.5k +103,540
37 Trexquant Investment LP 0.02% of their portfolio STAMFORD, CT 281,060281.1k $1.4m $1.4m 0.02% Added +168.4k +168,428
38 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 273,272273.3k $1.4m $1.4m 0.00% Reduced -160.3k -160,305
39 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 234,931234.9k $1.2m $1.2m 0.00% Reduced -105.7k -105,747
40 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 225,402225.4k $1.1m $1.1m 0.00% Added +27.5k +27,524
41 Ghost Tree Capital, LLC 0.35% of their portfolio NEW YORK, NY 200,000200.0k $998.0k $998.0k 0.35% New
42 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 183,946183.9k $917.9k $917.9k 0.00% Reduced -68.0k -68,000
43 Moody Aldrich Partners LLC 0.17% of their portfolio MARBLEHEAD, MA 179,359179.4k $895.0k $895.0k 0.17% New
44 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 171,049171.0k $853.5k $853.5k 0.00% Added +96.0k +95,996
45 BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio NEW YORK, NY 167,556167.6k $836.1k $836.1k 0.03% Reduced -4.4k -4,370
46 Swiss National Bank 0.00% of their portfolio ZURICH, V8 156,500156.5k $780.9k $780.9k 0.00% Unchanged
47 a16z Perennial Management, L.P. 0.04% of their portfolio MENLO PARK, CA 155,238155.2k $774.6k $774.6k 0.04% Added +77.6k +77,619
48 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 139,790139.8k $697.6k $697.6k 0.00% Added +4.9k +4,914
49 PRELUDE CAPITAL MANAGEMENT, LLC 0.06% of their portfolio NEW YORK, NY 135,200135.2k $674.6k $674.6k 0.06% Reduced -9.1k -9,100
50 SG Americas Securities, LLC 0.00% of their portfolio NEW YORK, NY 133,827133.8k $668.0k $668.0k 0.00% New
51 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 125,834125.8k $627.9k $627.9k 0.00% Added +4.1k +4,092
52 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 124,679124.7k $622.1k $622.1k 0.00% Reduced -292.0k -292,046
53 UBS Group AG 0.00% of their portfolio ZURICH, V8 119,913119.9k $598.4k $598.4k 0.00% Added +37.6k +37,592
54 Point72 Asset Management, L.P. 0.00% of their portfolio STAMFORD, CT 115,478115.5k $576.2k $576.2k 0.00% Reduced -1.9m -1,859,259
55 D. E. Shaw & Co., Inc. 0.00% of their portfolio New York, NY 108,567108.6k $541.7k $541.7k 0.00% Reduced -176.5k -176,525
56 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 106,542106.5k $531.6k $531.6k 0.00% Added +69.2k +69,207
57 Schonfeld Strategic Advisors LLC 0.00% of their portfolio NEW YORK, NY 102,635102.6k $512.1k $512.1k 0.00% New
58 Cinctive Capital Management LP 0.03% of their portfolio New York, NY 100,162100.2k $499.8k $499.8k 0.03% Added +31.8k +31,756
59 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 95,35595.4k $475.8k $475.8k 0.00% Reduced -1.8k -1,787
60 James J. Burns & Company, LLC 0.09% of their portfolio MELVILLE, NY 90,00090.0k $449.0k $449.0k 0.09% New
61 PDT Partners, LLC 0.04% of their portfolio New York, NY 89,26789.3k $445.4k $445.4k 0.04% Added +76.0k +75,967
62 MARTINGALE ASSET MANAGEMENT L P 0.01% of their portfolio BOSTON, MA 88,54788.5k $441.9k $441.9k 0.01% Added +19.6k +19,643
63 STRS OHIO 0.00% of their portfolio COLUMBUS, OH 85,30085.3k $425.6k $425.6k 0.00% Added +14.0k +14,000
64 Legal & General Group Plc 0.00% of their portfolio London, X0 82,11182.1k $409.7k $409.7k 0.00% Added +11.0k +10,959
65 MACQUARIE GROUP LTD 0.00% of their portfolio Sydney, NSW 2000, C3 81,95582.0k $409.0k $409.0k 0.00% Unchanged
66 Birchview Capital, LP 0.18% of their portfolio BURLINGTON, VT 80,00080.0k $399.2k $399.2k 0.18% Unchanged
67 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 78,04878.0k $389.5k $389.5k 0.00% New
68 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 77,76877.8k $388.1k $388.1k 0.00% Reduced -907 -907
69 ADAR1 Capital Management, LLC 0.08% of their portfolio AUSTIN, TX 76,65176.7k $382.5k $382.5k 0.08% Added +46.7k +46,651
70 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 75,07375.1k $374.6k $374.6k 0.00% Reduced -18.4k -18,413
71 Engineers Gate Manager LP 0.01% of their portfolio NEW YORK, NY 70,07170.1k $349.7k $349.7k 0.01% Added +19.9k +19,903
72 Y-Intercept (Hong Kong) Ltd 0.02% of their portfolio HONG KONG, K3 68,80368.8k $343.3k $343.3k 0.02% New
73 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 62,10262.1k $309.9k $309.9k 0.00% Reduced -251.3k -251,303
74 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 58,74358.7k $293.1k $293.1k 0.00% Reduced -35.1k -35,051
75 GSA CAPITAL PARTNERS LLP 0.02% of their portfolio LONDON, X0 55,25855.3k $276.0k $276.0k 0.02% Reduced -39.8k -39,779
76 JANUS HENDERSON GROUP PLC 0.00% of their portfolio LONDON, X0 51,70051.7k $256.9k $256.9k 0.00% New
77 Mitsubishi UFJ Asset Management Co., Ltd. 0.00% of their portfolio TOKYO, M0 45,55745.6k $227.3k $227.3k 0.00% New
78 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 43,60143.6k $217.6k $217.6k 0.00% Added +5.5k +5,533
79 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 41,65641.7k $207.9k $207.9k 0.00% First filing
80 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 37,42137.4k $186.7k $186.7k 0.00% First filing
81 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 35,14235.1k $175.4k $175.4k 0.00% Reduced -8.9k -8,851
82 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 33,52933.5k $167.3k $167.3k 0.00% Added +7.0k +6,973
83 Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio ZURICH, V8 33,49133.5k $167.1k $167.1k 0.00% Added +14.4k +14,371
84 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 33,13133.1k $165.3k $165.3k 0.00% Added +4.9k +4,913
85 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 28,70028.7k $143.2k $143.2k 0.00% Reduced -57.4k -57,400
86 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 27,56927.6k $137.6k $137.6k 0.00% Added +1.5k +1,490
87 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 27,46327.5k $137.0k $137.0k 0.00% Added +13.4k +13,387
88 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 26,88026.9k $134.1k $134.1k 0.00% Added +4.0k +3,997
89 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 26,09526.1k $130.2k $130.2k 0.00% New
90 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 25,99426.0k $129.7k $129.7k 0.00% Reduced -350 -350
91 Verition Fund Management LLC 0.00% of their portfolio GREENWICH, CT 25,91725.9k $129.3k $129.3k 0.00% Reduced -7.0k -7,040
92 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 24,71624.7k $123.3k $123.3k 0.00% Reduced -59.9k -59,913
93 GLENMEDE TRUST CO NA 0.00% of their portfolio PHILADELPHIA, PA 22,84022.8k $114.0k $114.0k 0.00% New
94 ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio PHOENIX, AZ 22,25122.3k $111.0k $111.0k 0.00% Added +455 +455
95 HSBC HOLDINGS PLC 0.00% of their portfolio LONDON, X0 21,44421.4k $104.4k $104.4k 0.00% New
96 KRAEMATON INVESTMENT ADVISORS, INC 0.10% of their portfolio BRAINTREE, MA 19,00019.0k $94.8k $94.8k 0.10% Reduced -3.0k -3,000
97 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 18,82018.8k $93.9k $93.9k 0.00% Added +185 +185
98 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.00% of their portfolio BALA CYNWYD, PA 18,74418.7k $93.5k $93.5k 0.00% Reduced -46.8k -46,821
99 TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio AUSTIN, TX 17,45317.5k $87.0k $87.0k 0.00% Reduced -203 -203
100 ProShare Advisors LLC 0.00% of their portfolio BETHESDA, MD 17,41017.4k $86.9k $86.9k 0.00% Reduced -4.4k -4,354