CRISPR THERAPEUTICS AG CRSP
NAMEN AKT · Common Stock · CUSIP H17182108
Company in Basel, Switzerland
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersZug, Switzerland
- Founded2013
- Websitecrisprtx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($180.9m this quarter). Holder counts are more reliable. Shares outstanding: 85.2m as of 2024-08-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $53.99. Options: 28 managers hold calls ($127.4m notional), 24 hold puts ($119.5m).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 437 |
| Q4 2022 | 398 |
| Q1 2023 | 381 |
| Q2 2023 | 419 |
| Q3 2023 | 409 |
| Q4 2023 | 473 |
| Q1 2024 | 484 |
| Q2 2024 | 450 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 159 | 206 |
| Q1 2023 | 149 | 175 |
| Q2 2023 | 155 | 161 |
| Q3 2023 | 195 | 152 |
| Q4 2023 | 232 | 170 |
| Q1 2024 | 229 | 194 |
| Q2 2024 | 202 | 204 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $80.5m | $91.5m | 1.14 |
| Q4 2023 | $316.7m | $301.2m | 0.95 |
| Q1 2024 | $258.3m | $214.0m | 0.83 |
| Q2 2024 | $127.4m | $119.5m | 0.94 |
Biggest buyers
| STATE STREET CORP | Added | +898.5k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Added | +583.5k |
| BlackRock Inc. | Added | +231.4k |
| TANG CAPITAL MANAGEMENT LLC | Added | +200.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | +187.6k |
| MARSHALL WACE, LLP | New | +186.6k |
| JANE STREET GROUP, LLC | Added | +174.9k |
| TWINBEECH CAPITAL LP | New | +146.5k |
| GOLDMAN SACHS GROUP INC | Added | +132.7k |
| FMR LLC | Added | +113.4k |
Biggest sellers
| MORGAN STANLEY | Reduced | -2.7m |
| Avoro Capital Advisors LLC | Sold out | -419.6k |
| ARK Investment Management LLC | Reduced | -378.5k |
| BARCLAYS PLC | Reduced | -190.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -179.5k |
| Mirae Asset Global Investments Co., Ltd. | Reduced | -164.0k |
| D. E. Shaw & Co., Inc. | Reduced | -146.1k |
| Pictet Asset Management Holding SA | Reduced | -130.1k |
| JPMORGAN CHASE & CO | Reduced | -127.4k |
| Sumitomo Mitsui Trust Group, Inc. | Reduced | -117.3k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $20.0m371.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $19.0m352.0k shares |
| JANE STREET GROUP, LLC | Reduced | $11.9m220.7k shares |
| SIMPLEX TRADING, LLC | Reduced | $10.3m190.9k shares |
| PEAK6 Investments LLC | Reduced | $10.0m185.8k shares |
| IMC-Chicago, LLC | Added | $8.1m149.1k shares |
| Caption Management, LLC | Reduced | $7.3m135.0k shares |
| BARCLAYS PLC | Added | $6.2m114.0k shares |
| GROUP ONE TRADING LLC | Reduced | $4.8m88.3k shares |
| CAPITAL FUND MANAGEMENT S.A. | Reduced | $4.6m85.4k shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $38.4m710.8k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $25.9m480.4k shares |
| Eagle Health Investments LP | Unchanged | $10.6m197.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $8.1m150.0k shares |
| GROUP ONE TRADING LLC | Reduced | $5.8m107.3k shares |
| IMC-Chicago, LLC | Reduced | $4.2m78.5k shares |
| GTS SECURITIES LLC | Added | $4.0m74.7k shares |
| CAPITAL FUND MANAGEMENT S.A. | Reduced | $4.0m74.2k shares |
| Caption Management, LLC | Reduced | $3.0m55.0k shares |
| JANE STREET GROUP, LLC | Reduced | $2.9m54.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARK Investment Management LLC 13G · institution +1.0 pts · filed 2026-04-30 | 11.8% |
| BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-07-27 | 8.3% |
| ORBIS INVESTMENT MANAGEMENT LTD 13G · institution -0.7 pts · filed 2026-08-14 | 5.6% |
| Capital World Investors 13G · institution new · filed 2026-05-14 | 5.1% |
Fell to 5% or below in the last year: Capital International Investors (1.2%, 2026-02-05)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 1 | $5.2m | — |
| Q4 2022 | 0 | — | 1 | $3.7m | — |
| Q1 2023 | 0 | — | 1 | $3.6m | — |
| Q2 2023 | 0 | — | 1 | $2.9m | $2.9m |
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 3 | $9.7m | $7.3m |
| Q2 2024 | 0 | — | 2 | $1.4m | $1.2m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-06-21 | Bruno Julianne Chief Operating Officer | Sold | $188.8k3.4k shares |
| 2024-04-15 | Kulkarni Samarth Chief Executive Officer, director | Sold plan | $1.2m19.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| Capital International Investors 0.09% of their portfolio | 7.9m $424.8m | Added +28.2k |
| ARK Investment Management LLC 3.73% of their portfolio | 7.8m $420.1m | Reduced -378.5k |
| Sumitomo Mitsui Trust Group, Inc. 0.13% of their portfolio | 3.2m $170.2m | Reduced -117.3k |
| Amova Asset Management Americas, Inc. 1.96% of their portfolio | 3.2m $170.0m | Reduced -117.3k |
| BlackRock Inc. 0.00% of their portfolio | 2.8m $150.0m | Added +231.4k |
| T. Rowe Price Investment Management, Inc. 0.09% of their portfolio | 2.7m $147.5m | Added +26.3k |
| STATE STREET CORP 0.01% of their portfolio | 2.4m $129.3m | Added +898.5k |
| FMR LLC 0.01% of their portfolio | 2.4m $127.1m | Added +113.4k |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.7m $94.4m | Added +111.7k |
| NEA Management Company, LLC 6.45% of their portfolio | 1.6m $85.8m | Unchanged |
| EcoR1 Capital, LLC 2.30% of their portfolio | 1.4m $75.0m | Unchanged |
| SR One Capital Management, LP 17.74% of their portfolio | 1.0m $56.7m | Unchanged |
| LOOMIS SAYLES & CO L P 0.07% of their portfolio | 1.0m $54.3m | Reduced -19.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 973.0k $52.6m | Added +63.7k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 950.1k $51.3m | Added +19.1k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 941.5k $50.9m | Added +78.3k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 717.6k $38.8m | Added +48.4k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 694.0k $37.5m | Added +583.5k |
| Contrarius Investment Management Ltd 2.32% of their portfolio | 685.7k $37.0m | Added +19.7k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 658.1k $35.5m | Reduced -127.4k |
| NORGES BANK 0.01% of their portfolio | 650.2k $35.1m | Added +59.9k |
| Bellevue Group AG 0.54% of their portfolio | 617.6k $33.4m | Reduced -2.3k |
| MORGAN STANLEY 0.00% of their portfolio | 597.7k $32.3m | Reduced -2.7m |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.17% of their portfolio | 530.0k $28.6m | Not comparable |
| Versant Venture Management, LLC 34.84% of their portfolio | 498.6k $26.9m | Unchanged |
| FEDERATED HERMES, INC. 0.06% of their portfolio | 447.6k $24.2m | Unchanged |
| UBS Group AG 0.01% of their portfolio | 424.2k $22.9m | Added +103.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 420.7k $22.7m | Reduced -179.5k |
| BAILLIE GIFFORD & CO 0.02% of their portfolio | 405.4k $21.9m | Added +9.5k |
| JANE STREET GROUP, LLC 0.02% of their portfolio | 349.9k $18.9m | Added +174.9k |
| TANG CAPITAL MANAGEMENT LLC 1.74% of their portfolio | 316.5k $17.1m | Added +200.0k |
| CAPITAL ADVISORS INC/OK 0.31% of their portfolio | 278.0k $15.0m | Added +14.0k |
| Squarepoint Ops LLC 0.05% of their portfolio | 268.8k $14.5m | Reduced -5.2k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 265.3k $14.3m | Added +132.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.02% of their portfolio | 260.8k $14.1m | Added +187.6k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 233.4k $12.6m | Reduced -9.9k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 227.6k $12.3m | Added +11.2k |
| Cutter Capital Management, LP 3.32% of their portfolio | 201.5k $10.9m | Reduced -38.9k |
| ARMISTICE CAPITAL, LLC 0.28% of their portfolio | 198.4k $10.7m | Added +6.4k |
| Vestmark Advisory Solutions, Inc. 0.45% of their portfolio | 197.6k $10.7m | Reduced -51.9k |
| Pictet Asset Management Holding SA 0.01% of their portfolio | 190.4k $10.3m | Reduced -130.1k |
| MARSHALL WACE, LLP 0.01% of their portfolio | 186.6k $10.1m | New |
| Rafferty Asset Management, LLC 0.04% of their portfolio | 182.6k $9.9m | Added +59.0k |
| Spear Holdings RSC Ltd 6.29% of their portfolio | 165.0k $8.9m | Unchanged |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 162.9k $8.8m | Added +6.1k |
| TD Asset Management Inc 0.01% of their portfolio | 159.6k $8.6m | Reduced -7.2k |
| Swiss National Bank 0.01% of their portfolio | 158.7k $8.6m | Added +9.8k |
| Integral Health Asset Management, LLC 0.81% of their portfolio | 150.0k $8.1m | Reduced -70.0k |
| CAPITAL INTERNATIONAL SARL 0.25% of their portfolio | 149.4k $8.1m | Added +7.5k |
| TWINBEECH CAPITAL LP 0.16% of their portfolio | 146.5k $7.9m | New |
| California Public Employees Retirement System 0.01% of their portfolio | 143.1k $7.7m | Added +35.4k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 142.6k $7.7m | Reduced -94.5k |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 136.3k $7.4m | Reduced -12.6k |
| BLAIR WILLIAM & CO/IL 0.02% of their portfolio | 135.0k $7.3m | Reduced -12.9k |
| NORDEA INVESTMENT MANAGEMENT AB 0.01% of their portfolio | 126.9k $6.9m | Reduced -21.8k |
| Woodline Partners LP 0.07% of their portfolio | 126.8k $6.9m | Reduced -36.7k |
| CAPITAL INTERNATIONAL LTD /CA/ 0.31% of their portfolio | 126.1k $6.8m | Reduced -639 |
| LPL Financial LLC 0.00% of their portfolio | 116.1k $6.3m | Added +10.2k |
| Reynders McVeigh Capital Management, LLC 0.35% of their portfolio | 114.7k $6.2m | Added +17.7k |
| Capital International, Inc./CA/ 0.07% of their portfolio | 102.2k $5.5m | Added +10.5k |
| Carnegie Investment Counsel 0.17% of their portfolio | 102.1k $5.5m | Added +34.5k |
| Handelsbanken Fonder AB 0.02% of their portfolio | 100.3k $5.4m | Added +83.6k |
| BAKER BROS. ADVISORS LP 0.07% of their portfolio | 100.0k $5.4m | New |
| Baker Chad R 1.11% of their portfolio | 98.5k $5.3m | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 94.1k $5.1m | Added +11.2k |
| Rockefeller Capital Management L.P. 0.01% of their portfolio | 94.0k $5.1m | Added +14.9k |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 90.7k $4.9m | New |
| OSAIC HOLDINGS, INC. 0.01% of their portfolio | 88.4k $4.8m | Reduced -2.6k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 86.4k $4.7m | Added +1.6k |
| VAN ECK ASSOCIATES CORP 0.01% of their portfolio | 79.8k $4.3m | Added +7.8k |
| Slow Capital, Inc. 0.69% of their portfolio | 79.2k $4.3m | Added +11.6k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 78.7k $4.3m | Added +3.4k |
| Private Advisor Group, LLC 0.03% of their portfolio | 77.6k $4.2m | Added +64.1k |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. 0.30% of their portfolio | 77.5k $4.2m | Added +8.5k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.01% of their portfolio | 77.0k $4.2m | First filing |
| LAZARD ASSET MANAGEMENT LLC 0.01% of their portfolio | 74.2k $4.0m | Reduced -11.9k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 72.9k $3.9m | Added +5.0k |
| GROUP ONE TRADING LLC 0.12% of their portfolio | 68.5k $3.7m | Added +44.9k |
| BARCLAYS PLC 0.00% of their portfolio | 65.6k $3.5m | Reduced -190.7k |
| CONGRESS ASSET MANAGEMENT CO 0.02% of their portfolio | 64.0k $3.5m | Reduced -625 |
| COMMONWEALTH EQUITY SERVICES, LLC 0.01% of their portfolio | 61.6k $3.3m | Added +7.6k |
| McGuire Investment Group, LLC 0.45% of their portfolio | 57.9k $3.1m | Reduced -118 |
| Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio | 57.4k $3.1m | Added +11.4k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 55.3k $3.0m | Added +550 |
| GUGGENHEIM CAPITAL LLC 0.02% of their portfolio | 53.4k $2.9m | Added +3.4k |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.03% of their portfolio | 53.3k $2.9m | Reduced -48.8k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 50.4k $2.7m | Reduced -9.0k |
| PDT Partners, LLC 0.26% of their portfolio | 50.1k $2.7m | Added +32.7k |
| Thrivent Financial for Lutherans 0.01% of their portfolio | 47.2k $2.6m | Added +16.1k |
| GTS SECURITIES LLC 0.05% of their portfolio | 41.2k $2.2m | Added +21.9k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 40.7k $2.3m | Unchanged |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 40.6k $2.2m | Reduced -671 |
| HighTower Advisors, LLC 0.00% of their portfolio | 39.7k $2.1m | Reduced -2.9k |
| Curi Capital, LLC 0.05% of their portfolio | 39.1k $2.1m | Added +4.8k |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 38.4k $2.1m | Added +3.5k |
| CITIGROUP INC 0.00% of their portfolio | 38.1k $2.1m | Reduced -63.4k |
| WESTWOOD HOLDINGS GROUP INC 0.01% of their portfolio | 37.4k $2.0m | Added +22.5k |
| Del-Sette Capital Management, LLC 1.63% of their portfolio | 36.8k $2.0m | New |
| B & T Capital Management DBA Alpha Capital Management 0.39% of their portfolio | 36.6k $2.0m | Reduced -7.6k |
| Asset Management One Co., Ltd. 0.01% of their portfolio | 36.0k $1.9m | Added +8.9k |