GH RESEARCH PLC GHRS
ORDINARY SHARES · Common Stock · CUSIP G3855L106
- SectorHealth care
- IndustryPharmaceutical Preparations
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $26.88. Options: 5 managers hold calls ($1.7m notional), 2 hold puts ($365.6k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 34 |
| Q4 2022 | 33 |
| Q1 2023 | 30 |
| Q2 2023 | 35 |
| Q3 2023 | 30 |
| Q4 2023 | 36 |
| Q1 2024 | 33 |
| Q2 2024 | 29 |
| Q3 2024 | 29 |
| Q4 2024 | 32 |
| Q1 2025 | 37 |
| Q2 2025 | 39 |
| Q3 2025 | 47 |
| Q4 2025 | 53 |
| Q1 2026 | 54 |
| Q2 2026 | 63 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 9 | 11 |
| Q4 2024 | 11 | 8 |
| Q1 2025 | 23 | 16 |
| Q2 2025 | 20 | 15 |
| Q3 2025 | 32 | 15 |
| Q4 2025 | 31 | 23 |
| Q1 2026 | 31 | 23 |
| Q2 2026 | 35 | 25 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $185.9k | $424.5k | 2.28 |
| Q4 2025 | $547.4k | $990.6k | 1.81 |
| Q1 2026 | $161.7k | $2.8k | 0.02 |
| Q2 2026 | $1.7m | $365.6k | 0.22 |
Biggest buyers
| Deep Track Capital, LP | New | +3.3m |
| Lynx1 Capital Management LP | Added | +2.5m |
| FMR LLC | Added | +841.0k |
| Foresite Capital Management VI LLC | Added | +625.0k |
| BRAIDWELL LP | New | +207.2k |
| JANE STREET GROUP, LLC | New | +170.0k |
| GOLDMAN SACHS GROUP INC | Added | +103.9k |
| Trexquant Investment LP | Added | +84.0k |
| HRT FINANCIAL LP | New | +65.4k |
| UBS Group AG | Added | +65.0k |
Biggest sellers
| TORONTO DOMINION BANK | Sold out | -1.4m |
| Troluce Capital Advisors LLC | Sold out | -990.5k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -614.5k |
| 5AM Venture Management, LLC | Sold out | -572.7k |
| Squadron Capital Management LLC | Sold out | -325.0k |
| CenterBook Partners LP | Reduced | -147.1k |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | -80.8k |
| Occam Crest Management LP | Sold out | -80.0k |
| HighVista Strategies LLC | Reduced | -54.4k |
| MARSHALL WACE, LLP | Reduced | -44.4k |
Biggest calls
| JANE STREET GROUP, LLC | New | $787.6k29.3k shares |
| CITADEL ADVISORS LLC | New | $532.2k19.8k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $360.2k13.4k shares |
| GROUP ONE TRADING LLC | Unchanged | $2.7k100 shares |
| SIMPLEX TRADING, LLC | Reduced | $2.7k100 shares |
Biggest puts
| JANE STREET GROUP, LLC | New | $360.2k13.4k shares |
| SIMPLEX TRADING, LLC | Added | $5.4k200 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Lynx1 Capital Management LP 13G · passive investor +1.9 pts · filed 2026-08-14 | 19.3% |
| BIOTECHNOLOGY VALUE FUND L P 13G · exempt (held before listing) filed 2025-05-15 | 14.2% |
| RTW INVESTMENTS, LP 13G · institution filed 2025-05-15 | 8.9% |
| FMR LLC 13G · institution +1.3 pts · filed 2025-08-06 | 8.2% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor -5.3 pts · filed 2026-08-14 | 7.1% |
Fell to 5% or below in the last year: Terwey Theis H (2.9%, 2025-11-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported since 1 Apr 2026.
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Lynx1 Capital Management LP 41.19% of their portfolio | 13.3m $356.5m | Added +2.5m |
| BVF INC/IL 5.95% of their portfolio | 8.7m $232.5m | Unchanged |
| RA CAPITAL MANAGEMENT, L.P. 1.78% of their portfolio | 7.6m $205.3m | Reduced -39.9k |
| FMR LLC 0.01% of their portfolio | 6.0m $160.7m | Added +841.0k |
| RTW INVESTMENTS, LP 1.36% of their portfolio | 5.9m $159.5m | Unchanged |
| Deep Track Capital, LP 1.32% of their portfolio | 3.3m $89.6m | New |
| Avoro Capital Advisors LLC 0.43% of their portfolio | 1.8m $48.4m | Unchanged |
| Foresite Capital Management VI LLC 3.93% of their portfolio | 940.5k $25.3m | Added +625.0k |
| Jefferies Financial Group Inc. 0.18% of their portfolio | 712.3k $19.1m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 480.3k $12.9m | Added +24.7k |
| UBS Group AG 0.00% of their portfolio | 477.4k $12.8m | Added +65.0k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 323.4k $8.7m | Reduced -614.5k |
| BRAIDWELL LP 0.21% of their portfolio | 207.2k $5.6m | New |
| BOOTHBAY FUND MANAGEMENT, LLC 0.10% of their portfolio | 202.1k $5.4m | Reduced -80.8k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 170.0k $4.6m | New |
| HighVista Strategies LLC 0.97% of their portfolio | 158.8k $4.3m | Reduced -54.4k |
| Trexquant Investment LP 0.03% of their portfolio | 153.8k $4.1m | Added +84.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 148.7k $4.0m | Added +103.9k |
| XTX Topco Ltd 0.03% of their portfolio | 87.0k $2.3m | Added +34.9k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 86.0k $2.3m | Added +20.5k |
| AdvisorShares Investments LLC 0.23% of their portfolio | 71.3k $1.9m | Added +4.2k |
| CenterBook Partners LP 0.09% of their portfolio | 69.4k $1.9m | Reduced -147.1k |
| HRT FINANCIAL LP 0.00% of their portfolio | 65.4k $1.8m | New |
| MORGAN STANLEY 0.00% of their portfolio | 52.2k $1.4m | Added +26.4k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 50.9k $1.4m | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 46.7k $1.3m | Reduced -44.4k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 43.9k $1.2m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 40.5k $1.1m | Unchanged |
| Axxion S.A. 0.07% of their portfolio | 36.2k $972.2k | First filing |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 34.3k $921.4k | Added +15.7k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 31.8k $856.0k | Reduced -841 |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 25.3k $681.3k | New |
| Quadrature Capital Ltd 0.00% of their portfolio | 21.1k $567.6k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 18.8k $535.0k | Reduced -75 |
| Squarepoint Ops LLC 0.00% of their portfolio | 18.4k $495.4k | New |
| Virtus Investment Advisers, LLC 0.10% of their portfolio | 15.5k $416.4k | Reduced -5.4k |
| LETKO, BROSSEAU & ASSOCIATES INC 0.01% of their portfolio | 15.4k $414.6k | New |
| China Universal Asset Management Co., Ltd. 0.02% of their portfolio | 13.4k $360.7k | Reduced -88 |
| HighTower Advisors, LLC 0.00% of their portfolio | 12.7k $341.4k | Reduced -2.9k |
| STATE STREET CORP 0.00% of their portfolio | 11.2k $300.1k | Added +114 |
| Lion Point Capital, LP 1.31% of their portfolio | 10.2k $274.2k | Unchanged |
| Eversept Partners, LP 0.01% of their portfolio | 8.7k $233.1k | New |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 7.8k $216.4k | New |
| BARCLAYS PLC 0.00% of their portfolio | 6.0k $160.7k | Added +1.6k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 5.9k $158.0k | Added +3.3k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 5.8k $155.2k | Reduced -150 |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 4.7k $127.4k | Added +4.7k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 3.1k $82.5k | Reduced -167 |
| North Star Investment Management Corp. 0.00% of their portfolio | 2.2k $59.1k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 1.7k $45.6k | Added +387 |
| CITIGROUP INC 0.00% of their portfolio | 1.6k $43.4k | Reduced -119 |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.3k $35.3k | Reduced -69 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 1.2k $33.6k | Unchanged |
| HARBOUR INVESTMENTS, INC. 0.00% of their portfolio | 800 $21.5k | New |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 775 $21.9k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 515 $13.8k | Reduced -150 |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 411 $11.0k | Added +391 |
| Ancora Advisors LLC 0.00% of their portfolio | 284 $7.6k | Unchanged |
| HOLLENCREST CAPITAL MANAGEMENT 0.00% of their portfolio | 250 $6.7k | New |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 205 $5.5k | New |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 100 $2.7k | Unchanged |
| Cornerstone Financial Management LLC 0.00% of their portfolio | 32 $860 | Unchanged |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 19 $511 | New |