TWIST BIOSCIENCE CORP TWST
COM · Common Stock · CUSIP 90184D100 · ISIN US90184D1000
Biotechnology company
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSouth San Francisco, CA
- Founded2013
- Websitetwistbioscience.com
- FilingsSEC EDGAR
222
institutional holders
58.1m
shares reported held*
103.0%
of all shares outstanding*
$2.0bnreported value*
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($5.3m this quarter). Holder counts are more reliable. Shares outstanding: 56.4m as of 2022-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $35.04. Options: 9 managers hold calls ($5.5m notional), 8 hold puts ($3.7m).
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $2.4m67.9k shares |
| NOMURA HOLDINGS INC | — | $1.2m32.7k shares |
| JANE STREET GROUP, LLC | — | $987.0k28.0k shares |
| CITADEL ADVISORS LLC | — | $694.0k19.7k shares |
| SIMPLEX TRADING, LLC | — | $112.0k3.2k shares |
| GROUP ONE TRADING LLC | — | $109.0k3.1k shares |
| Walleye Trading LLC | — | $85.0k2.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | — | $00 shares |
| Cutler Group LLC / CA | — | $0100 shares |
Biggest puts
| FRED ALGER MANAGEMENT, LLC | — | $2.3m64.0k shares |
| D. E. Shaw & Co., Inc. | — | $705.0k20.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $338.0k9.6k shares |
| CITADEL ADVISORS LLC | — | $226.0k6.4k shares |
| Walleye Trading LLC | — | $159.0k4.5k shares |
| SIMPLEX TRADING, LLC | — | $42.0k1.2k shares |
| GROUP ONE TRADING LLC | — | $4.0k100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | — | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +5.6 pts · filed 2026-09-08 | 13.2% |
| BlackRock, Inc. 13G · institution filed 2025-04-17 | 8.3% |
| Artisan Partners Limited Partnership 13G · institution -2.4 pts · filed 2026-08-13 | 7.7% |
| PRICE T ROWE ASSOCIATES INC /MD/ 13G · institution new · filed 2026-08-14 | 5.8% |
| ARK Investment Management LLC 13G · institution -2.2 pts · filed 2026-09-08 | 5.1% |
| STATE STREET CORP 13G · institution +0.8 pts · filed 2025-11-10 | 5.1% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.0% |
Fell to 5% or below in the last year: EdgePoint Investment Group Inc. (4.2%, 2026-08-14), WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC (3.5%, 2026-08-11), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q3 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
BuyingSelling
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2020 | 0 | — | 0 | — | — |
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 7 | $20.2m | — |
| Q1 2022 | 0 | — | 6 | $909.2k | — |
| Q2 2022 | 1 | $250.1k | 3 | $940.0k | — |
| Q3 2022 | 0 | — | 3 | $1.1m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-09-16 | Green Paula SVP of Human Resources | Sold | $318.7k8.5k shares |
| 2022-08-22 | Banyai William Officer, director | Sold | $53.5k1.3k shares |
| 2022-08-17 | THORBURN JAMES M Chief Financial Officer | Sold | $436.6k9.0k shares |
| 2022-08-16 | THORBURN JAMES M Chief Financial Officer | Sold | $251.0k4.9k shares |
| 2022-07-25 | Banyai William Officer, director | Sold | $16.3k378 shares |
| 2022-07-05 | Banyai William Officer, director | Sold | $11.7k318 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2022
| Manager | Shares | Change |
|---|---|---|
| ARK Investment Management LLC 1.64% of their portfolio | 6.7m $235.3m | — |
| VANGUARD GROUP INC 0.01% of their portfolio | 4.9m $173.3m | — |
| BlackRock Inc. 0.01% of their portfolio | 4.9m $172.8m | — |
| FMR LLC 0.01% of their portfolio | 3.3m $115.4m | — |
| JPMORGAN CHASE & CO 0.02% of their portfolio | 3.3m $115.2m | — |
| STATE STREET CORP 0.01% of their portfolio | 2.9m $100.9m | — |
| Sumitomo Mitsui Trust Group, Inc. 0.08% of their portfolio | 2.8m $99.4m | — |
| Amova Asset Management Americas, Inc. 1.12% of their portfolio | 2.8m $87.4m | — |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.27% of their portfolio | 2.0m $69.6m | — |
| VOYA INVESTMENT MANAGEMENT LLC 0.07% of their portfolio | 1.6m $54.9m | — |
| Jackson Square Partners, LLC 1.32% of their portfolio | 1.4m $50.2m | — |
| CREDIT SUISSE AG/ 0.06% of their portfolio | 1.4m $49.9m | — |
| MARSHALL WACE, LLP 0.11% of their portfolio | 1.2m $42.1m | — |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 1.0m $36.0m | — |
| BAILLIE GIFFORD & CO 0.03% of their portfolio | 891.0k $31.4m | — |
| MORGAN STANLEY 0.00% of their portfolio | 848.4k $29.9m | — |
| Tao Capital Management LP 19.15% of their portfolio | 828.8k $29.2m | — |
| Bank of New York Mellon Corp 0.01% of their portfolio | 821.2k $28.9m | — |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 811.2k $28.6m | — |
| Blue Water Life Science Advisors, LP 11.45% of their portfolio | 805.0k $28.4m | — |
| MILLENNIUM MANAGEMENT LLC 0.03% of their portfolio | 769.2k $27.1m | — |
| Capital World Investors 0.01% of their portfolio | 704.0k $24.8m | — |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 687.3k $24.2m | — |
| Fisher Asset Management, LLC 0.02% of their portfolio | 573.2k $20.2m | — |
| NORTHERN TRUST CORP 0.00% of their portfolio | 513.6k $18.1m | — |
| T. Rowe Price Investment Management, Inc. 0.01% of their portfolio | 472.3k $16.6m | — |
| NORGES BANK 0.00% of their portfolio | 461.5k $16.3m | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 410.0k $14.4m | — |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 378.6k $13.3m | — |
| Casdin Capital, LLC 0.85% of their portfolio | 365.0k $12.9m | — |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 342.8k $12.1m | — |
| Nicholas Investment Partners, LP 1.05% of their portfolio | 320.2k $11.3m | — |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 307.8k $10.8m | — |
| NanoDimension, Inc. 43.99% of their portfolio | 307.7k $10.8m | — |
| VICTORY CAPITAL MANAGEMENT INC 0.01% of their portfolio | 301.4k $10.6m | — |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.05% of their portfolio | 273.8k $9.6m | — |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 266.3k $9.4m | — |
| SEI INVESTMENTS CO 0.02% of their portfolio | 259.9k $9.2m | — |
| Balyasny Asset Management L.P. 0.03% of their portfolio | 234.6k $8.3m | — |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 207.5k $7.3m | — |
| Stanley-Laman Group, Ltd. 1.34% of their portfolio | 200.9k $7.1m | — |
| Cubist Systematic Strategies, LLC 0.04% of their portfolio | 160.8k $5.7m | — |
| Rafferty Asset Management, LLC 0.06% of their portfolio | 157.2k $5.5m | — |
| STATE OF MICHIGAN RETIREMENT SYSTEM 0.04% of their portfolio | 153.2k $5.4m | — |
| Lombard Odier Asset Management (Switzerland) SA 0.45% of their portfolio | 151.3k $5.3m | — |
| Invesco Ltd. 0.00% of their portfolio | 148.0k $5.2m | — |
| CITIGROUP INC 0.01% of their portfolio | 147.9k $5.2m | — |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 140.5k $5.0m | — |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 132.1k $4.7m | — |
| Swiss National Bank 0.00% of their portfolio | 126.7k $4.5m | — |
| California Public Employees Retirement System 0.00% of their portfolio | 120.2k $4.2m | — |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.05% of their portfolio | 119.6k $4.2m | — |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 118.5k $4.2m | — |
| Candriam S.C.A. 0.03% of their portfolio | 103.4k $3.6m | — |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 89.2k $3.1m | — |
| BANQUE PICTET & CIE SA 0.03% of their portfolio | 89.0k $3.1m | — |
| Legal & General Group Plc 0.00% of their portfolio | 86.9k $3.1m | — |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 85.0k $3.0m | — |
| NATIXIS 0.01% of their portfolio | 82.1k $2.9m | — |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 78.0k $2.7m | — |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 77.5k $2.7m | — |
| PUTNAM INVESTMENTS LLC 0.01% of their portfolio | 75.5k $2.7m | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 74.6k $2.6m | — |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 68.2k $2.4m | — |
| Altium Capital Management LLC 0.90% of their portfolio | 68.0k $2.4m | — |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 67.9k $2.4m | — |
| ROCKLAND TRUST CO 0.17% of their portfolio | 67.7k $2.4m | — |
| Slow Capital, Inc. 0.51% of their portfolio | 67.3k $2.4m | — |
| Homestead Advisers Corp 0.07% of their portfolio | 62.0k $2.2m | — |
| HRT FINANCIAL LP 0.02% of their portfolio | 59.5k $2.1m | — |
| Thrivent Financial for Lutherans 0.01% of their portfolio | 56.1k $2.0m | — |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 55.8k $2.0m | — |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 54.4k $1.9m | — |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 54.3k $1.9m | — |
| State of New Jersey Common Pension Fund D 0.01% of their portfolio | 52.8k $1.9m | — |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 49.9k $1.8m | — |
| Clarius Group, LLC 0.17% of their portfolio | 49.6k $1.7m | — |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 49.2k $1.7m | — |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 47.1k $1.7m | — |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 45.0k $1.6m | — |
| Trexquant Investment LP 0.05% of their portfolio | 44.2k $1.6m | — |
| Squarepoint Ops LLC 0.01% of their portfolio | 36.5k $1.3m | — |
| TD Asset Management Inc 0.00% of their portfolio | 36.0k $1.3m | — |
| Freemont Management S.A. 0.22% of their portfolio | 34.5k $1.2m | — |
| EXCHANGE TRADED CONCEPTS, LLC 0.04% of their portfolio | 34.3k $1.2m | — |
| Tower Research Capital LLC (TRC) 0.02% of their portfolio | 33.4k $1.2m | — |
| GUGGENHEIM CAPITAL LLC 0.01% of their portfolio | 29.9k $1.1m | — |
| MetLife Investment Management, LLC 0.01% of their portfolio | 29.7k $1.0m | — |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 28.5k $1.0m | — |
| ESSEX INVESTMENT MANAGEMENT CO LLC 0.16% of their portfolio | 28.2k $993.0k | — |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 27.1k $956.0k | — |
| Moody Aldrich Partners LLC 0.19% of their portfolio | 26.9k $946.0k | — |
| AMERICAN INTERNATIONAL GROUP, INC. 0.01% of their portfolio | 26.6k $939.0k | — |
| Comprehensive Financial Management LLC 0.02% of their portfolio | 26.3k $926.0k | — |
| UBS Group AG 0.00% of their portfolio | 25.7k $907.0k | — |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 25.0k $877.0k | — |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 25.0k $881.0k | — |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 24.5k $864.0k | — |
| SIT INVESTMENT ASSOCIATES INC 0.02% of their portfolio | 23.6k $830.0k | — |
| OCCUDO QUANTITATIVE STRATEGIES LP 0.06% of their portfolio | 22.4k $790.0k | — |