TREVI THERAPEUTICS INC TRVI
COM · Common Stock · CUSIP 89532M101
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersNew Haven, CT
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($596.0k this quarter). Holder counts are more reliable. Shares outstanding: 72.6m as of 2024-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.98. Options: 2 managers hold calls ($46.5k notional), 1 hold puts ($0).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 41 |
| Q4 2022 | 38 |
| Q1 2023 | 37 |
| Q2 2023 | 54 |
| Q3 2023 | 56 |
| Q4 2023 | 64 |
| Q1 2024 | 81 |
| Q2 2024 | 78 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 17 | 21 |
| Q1 2023 | 14 | 12 |
| Q2 2023 | 38 | 13 |
| Q3 2023 | 18 | 21 |
| Q4 2023 | 37 | 17 |
| Q1 2024 | 38 | 32 |
| Q2 2024 | 40 | 25 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $0 | $0 | — |
| Q4 2023 | $2.4k | $4.0k | 1.67 |
| Q1 2024 | $7.6k | $2.1k | 0.27 |
| Q2 2024 | $46.5k | $0 | 0.00 |
Biggest buyers
| Logos Global Management LP | Added | +3.4m |
| Ally Bridge Group (NY) LLC | New | +1.5m |
| BlackRock Inc. | Added | +759.4k |
| Rosalind Advisors, Inc. | Added | +465.6k |
| Tejara Capital Ltd | Added | +368.5k |
| ACUTA CAPITAL PARTNERS, LLC | New | +260.0k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +248.8k |
| MAI Capital Management | Added | +186.7k |
| MPM BIOIMPACT LLC | Added | +169.2k |
| VANGUARD GROUP INC | Added | +133.8k |
Biggest sellers
| Rubric Capital Management LP | Reduced | -537.2k |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | Reduced | -134.7k |
| MORGAN STANLEY | Reduced | -115.7k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -64.9k |
| Atom Investors LP | Sold out | -45.7k |
| CITADEL ADVISORS LLC | Sold out | -28.7k |
| Shay Capital LLC | Reduced | -25.2k |
| UBS Group AG | Reduced | -24.1k |
| AMERICAN INTERNATIONAL GROUP, INC. | Sold out | -20.8k |
| PFS Partners, LLC | Reduced | -20.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $46.5k15.6k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
New Enterprise Associates 16, L.P.
13D · may seek influence
-1.1 pts · filed 2026-05-07
Stated purposeThe Funds acquired the Firm Shares for investment purposes. Depending on market conditions, its continuing evaluation of the business and prospects of the Issuer and other factors, the Funds and other Reporting Persons may dispose of or acquire additional shares of the Issuer, including shares that may be acquired upon exercise of the NEA 16 Warrants prior to expiration. Except as set forth above, none of the Reporting Persons has any present plans which relate to or would result in: (a) The acquisition by any person of additional securities of the Issuer, or the disposition of securities of the Issuer; (b) An extraordinary corporate transaction, such as a merger, reorganization or liquidation, involving the Issuer or any of its subsidiaries; (c) A sale or transfer of a material amount … Full filing |
10.5% |
| FMR LLC 13G · institution +2.5 pts · filed 2026-08-06 | 8.8% |
| Frazier Life Sciences Public Fund, L.P. 13G · passive investor -3.6 pts · filed 2025-11-14 | 7.0% |
| BlackRock, Inc. 13G · institution +1.3 pts · filed 2026-10-27 | 6.9% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), Rubric Capital Management LP (2.9%, 2026-02-13), VIKING GLOBAL INVESTORS LP (4.2%, 2025-11-14)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 0 | — | — |
| Q1 2023 | 0 | — | 1 | $22.3k | — |
| Q2 2023 | 0 | — | 1 | $4.8k | $4.8k |
| Q3 2023 | 0 | — | 1 | $4.8k | $4.8k |
| Q4 2023 | 0 | — | 1 | $1.6k | $1.6k |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 3 | $232.5k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-05-29 | SCIASCIA THOMAS Chief Scientific Officer | Sold | $136.1k53.4k shares |
| 2024-05-22 | Delfini Lisa Chief Financial Officer | Sold | $11.5k4.3k shares |
| 2024-05-20 | GOOD JENNIFER L President & CEO, director | Sold | $71.6k25.0k shares |
| 2024-05-10 | GOOD JENNIFER L President & CEO, director | Sold | $13.3k4.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| NEA Management Company, LLC 2.55% of their portfolio | 11.4m $33.9m | Unchanged |
| Frazier Life Sciences Management, L.P. 1.03% of their portfolio | 7.4m $22.0m | Unchanged |
| Logos Global Management LP 0.97% of their portfolio | 5.6m $16.7m | Added +3.4m |
| Rubric Capital Management LP 0.40% of their portfolio | 5.0m $15.0m | Reduced -537.2k |
| VIKING GLOBAL INVESTORS LP 0.05% of their portfolio | 4.4m $13.1m | Unchanged |
| Venrock Adviser, LLC 0.65% of their portfolio | 3.4m $10.2m | Reduced -38 |
| BlackRock Inc. 0.00% of their portfolio | 3.1m $9.3m | Added +759.4k |
| Opaleye Management Inc. 1.80% of their portfolio | 2.6m $7.9m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.4m $7.3m | Added +133.8k |
| MPM BIOIMPACT LLC 0.70% of their portfolio | 1.5m $4.5m | Added +169.2k |
| Ally Bridge Group (NY) LLC 2.62% of their portfolio | 1.5m $4.4m | New |
| Rosalind Advisors, Inc. 3.28% of their portfolio | 1.4m $4.1m | Added +465.6k |
| MAI Capital Management 0.04% of their portfolio | 1.3m $3.9m | Added +186.7k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.1m $3.4m | Added +248.8k |
| STATE STREET CORP 0.00% of their portfolio | 899.9k $2.7m | Added +101.6k |
| SILVERARC CAPITAL MANAGEMENT, LLC 0.62% of their portfolio | 844.2k $2.5m | Unchanged |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 0.15% of their portfolio | 605.4k $1.8m | Reduced -134.7k |
| Checkpoint Capital L.P. 0.90% of their portfolio | 500.1k $1.5m | Reduced -6.0k |
| Tejara Capital Ltd 0.44% of their portfolio | 406.0k $1.2m | Added +368.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 321.1k $956.9k | Reduced -6.6k |
| ACUTA CAPITAL PARTNERS, LLC 0.65% of their portfolio | 260.0k $774.8k | New |
| Propel Bio Management, LLC 0.50% of their portfolio | 260.0k $774.8k | Unchanged |
| Simplify Asset Management Inc. 0.05% of their portfolio | 200.0k $596.0k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 185.5k $552.7k | Added +89.0k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 178.5k $532.0k | Added +49.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 150.9k $449.7k | Added +43.2k |
| J. Goldman & Co LP 0.02% of their portfolio | 148.9k $443.8k | Added +11.0k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 96.3k $287.1k | Added +21.5k |
| MORGAN STANLEY 0.00% of their portfolio | 89.0k $265.2k | Reduced -115.7k |
| Shay Capital LLC 0.07% of their portfolio | 88.5k $263.6k | Reduced -25.2k |
| PFS Partners, LLC 0.15% of their portfolio | 79.0k $235.4k | Reduced -20.0k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 75.2k $224.1k | Added +23.3k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 73.2k $218.1k | Added +35.2k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 72.2k $215.0k | Added +49.5k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 66.4k $197.8k | Added +49.3k |
| WealthTrust Axiom LLC 0.06% of their portfolio | 63.5k $189.2k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 62.7k $186.8k | Added +11.8k |
| OPPENHEIMER & CO INC 0.00% of their portfolio | 60.8k $181.2k | Added +404 |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 54.1k $161.2k | Added +7.9k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 51.9k $154.7k | Reduced -64.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 44.3k $132.0k | Added +22.3k |
| BAILARD, INC. 0.00% of their portfolio | 40.9k $121.9k | Unchanged |
| TRUST CO OF TOLEDO NA /OH/ 0.02% of their portfolio | 36.5k $108.8k | Unchanged |
| LPL Financial LLC 0.00% of their portfolio | 36.0k $107.3k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 33.9k $101.1k | Reduced -1.3k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 31.6k $94.2k | First filing |
| UNITED BANK 0.01% of their portfolio | 31.2k $93.0k | Added +2.8k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 24.5k $73.1k | Added +11.4k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 23.5k $70.0k | Added +6.6k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 22.4k $66.9k | Added +9.2k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 21.2k $63.0k | First filing |
| Invesco Ltd. 0.00% of their portfolio | 19.7k $58.8k | Reduced -165 |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 19.6k $60.8k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 19.0k $57.0k | Added +5.5k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 18.9k $56.3k | Reduced -3.8k |
| UBS Group AG 0.00% of their portfolio | 18.0k $53.7k | Reduced -24.1k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 15.4k $46.0k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 15.3k $45.5k | Added +207 |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 14.9k $44.5k | Reduced -6.7k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 13.9k $41.5k | Reduced -3.9k |
| CITIGROUP INC 0.00% of their portfolio | 13.0k $38.7k | Added +4.3k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 12.3k $36.7k | Added +2.2k |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 10.0k $29.8k | Unchanged |
| STRS OHIO 0.00% of their portfolio | 8.2k $24.4k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 7.1k $21.0k | Added +6.5k |
| Legal & General Group Plc 0.00% of their portfolio | 6.5k $19.5k | Added +2.6k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 5.5k $16.0k | Added +4.1k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 5.2k $15.4k | Reduced -15.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 4.3k $12.7k | Added +18 |
| FMR LLC 0.00% of their portfolio | 3.6k $10.7k | Added +69 |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.4k $10.2k | Unchanged |
| LANARK FINANCIAL, INC. 0.00% of their portfolio | 2.0k $5.0k | Unchanged |
| AMALGAMATED BANK 0.00% of their portfolio | 1.4k $4.0k | Unchanged |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 773 $2.3k | Unchanged |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 55 $159 | Unchanged |
| CWM, LLC 0.00% of their portfolio | 33 $0 | Added +30 |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 3 $9 | Unchanged |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |